thiorphan has been researched along with Anesthesia in 3 studies
Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A maximally effective dose of LY53857 (1 mg/kg) produced larger shifts of the dose-response curves to serotonin, 5-methoxytryptamine and alpha-methyl-serotonin than did a maximally effective dose of ketanserin (1 mg/kg)." | 1.28 | A pharmacologic examination of receptors mediating serotonin-induced bronchoconstriction in the anesthetized guinea pig. ( Buckner, CK; Dea, D; Krell, RD; Liberati, N, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baum, T | 1 |
| Becker, FT | 1 |
| Sybertz, EJ | 1 |
| Sabin, C | 1 |
| Desiderio, DM | 1 |
| Buckner, CK | 1 |
| Dea, D | 1 |
| Liberati, N | 1 |
| Krell, RD | 1 |
| Suh, HH | 1 |
| Tseng, LL | 1 |
3 other studies available for thiorphan and Anesthesia
| Article | Year |
|---|---|
Enkephalinase 'A' inhibition by thiorphan: central and peripheral cardiovascular effects.
Topics: Amino Acids, Sulfur; Anesthesia; Animals; Hemodynamics; Injections, Intraventricular; Male; Neprilys | 1983 |
A pharmacologic examination of receptors mediating serotonin-induced bronchoconstriction in the anesthetized guinea pig.
Topics: Anesthesia; Animals; Atropine; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Het | 1991 |
Intrathecal administration of thiorphan and bestatin enhances the antinociception and release of Met-enkephalin induced by beta-endorphin intraventricularly in anesthetized rats.
Topics: Aminopeptidases; Anesthesia; Animals; beta-Endorphin; Enkephalin, Methionine; Injections, Intraventr | 1990 |