thiorphan has been researched along with Airway Obstruction in 2 studies
Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Male Hartley guinea pigs were treated with the enkephalinase inhibitor thiorphan by inhaled or intravenous administration routes and potentiation of substance P-induced airway obstruction examined." | 7.68 | Effects of inhaled or intravenous thiorphan on substance P-induced airway obstruction. ( Cockerham, SL; Silbaugh, SA; Stengel, PW, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patterson, R | 1 |
| Harris, KE | 1 |
| Silbaugh, SA | 1 |
| Cockerham, SL | 1 |
| Stengel, PW | 1 |
2 other studies available for thiorphan and Airway Obstruction
| Article | Year |
|---|---|
Rhesus monkey airway responses to substance P.
Topics: Administration, Inhalation; Airway Obstruction; Animals; Antigens, Helminth; Ascaris; Asthma; Female | 1990 |
Effects of inhaled or intravenous thiorphan on substance P-induced airway obstruction.
Topics: Aerosols; Airway Obstruction; Animals; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs | 1991 |