thiorphan and Aging studies

Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

Excerpt	Relevance	Reference
"Our aim was to compare the efficacy and tolerability of loperamide and racecadotril in elderly patients with acute diarrhea."	9.14	Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes. ( Colosimo, M; Cucchiara, S; Curto, LS; De Sarro, G; Falcone, D; Gallelli, L; Luberto, L; Marigliano, NM; Mazzei, F; Rende, P; Tolotta, GA, 2010)
"Our aim was to compare the efficacy and tolerability of loperamide and racecadotril in elderly patients with acute diarrhea."	5.14	Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes. ( Colosimo, M; Cucchiara, S; Curto, LS; De Sarro, G; Falcone, D; Gallelli, L; Luberto, L; Marigliano, NM; Mazzei, F; Rende, P; Tolotta, GA, 2010)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

thiorphan and Aging

Research Excerpts

Research

Studies (1)

Authors

Trials

Authors	Studies
Gallelli, L	1
Colosimo, M	1
Tolotta, GA	1
Falcone, D	1
Luberto, L	1
Curto, LS	1
Rende, P	1
Mazzei, F	1
Marigliano, NM	1
De Sarro, G	1
Cucchiara, S	1