thioridazine has been researched along with Tuberculosis, Drug-Resistant in 15 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clarithromycin was not associated with excess SAEs in eight controlled trials in HIV-infected patients (RD 0." | 2.52 | Efficacy and safety of World Health Organization group 5 drugs for multidrug-resistant tuberculosis treatment. ( Butler-Laporte, G; Menzies, D; Winters, N, 2015) |
| "Thioridazine treatment resulted in a significant reduction of colony-forming-units of the susceptible (-4." | 1.36 | The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis. ( Aguilar, D; Amaral, L; Boeree, MJ; Hernandez-Pando, R; Magis-Escurra, C; Orozco, H; van Ingen, J; van Soolingen, D, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 12 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amaral, L | 8 |
| Martins, A | 1 |
| Spengler, G | 1 |
| Hunyadi, A | 1 |
| Molnar, J | 2 |
| Koutsouki, E | 1 |
| Dutta, NK | 2 |
| Pinn, ML | 1 |
| Karakousis, PC | 2 |
| Winters, N | 1 |
| Butler-Laporte, G | 1 |
| Menzies, D | 1 |
| Kristiansen, JE | 4 |
| Dastidar, SG | 2 |
| Palchoudhuri, S | 1 |
| Roy, DS | 1 |
| Das, S | 1 |
| Hendricks, O | 1 |
| Christensen, JB | 1 |
| Martins, M | 2 |
| Viveiros, M | 4 |
| van Soolingen, D | 1 |
| Hernandez-Pando, R | 1 |
| Orozco, H | 1 |
| Aguilar, D | 1 |
| Magis-Escurra, C | 1 |
| van Ingen, J | 2 |
| Boeree, MJ | 2 |
| Mazumdar, K | 1 |
| Machado, D | 1 |
| Couto, I | 1 |
| Perdigão, J | 1 |
| Rodrigues, L | 1 |
| Portugal, I | 1 |
| Baptista, P | 1 |
| Veigas, B | 1 |
10 reviews available for thioridazine and Tuberculosis, Drug-Resistant
| Article | Year |
|---|---|
The mechanism by which the phenothiazine thioridazine contributes to cure problematic drug-resistant forms of pulmonary tuberculosis: recent patents for "new use".
Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Humans; Mycobacterium tuberculosis; | 2013 |
Efficacy and safety of World Health Organization group 5 drugs for multidrug-resistant tuberculosis treatment.
Topics: Amoxicillin; Antitubercular Agents; Azithromycin; Cilastatin; Clarithromycin; Clavulanic Acid; HIV I | 2015 |
Phenothiazines as a solution for multidrug resistant tuberculosis: From the origin to present.
Topics: Antipsychotic Agents; Antitubercular Agents; Chlorpromazine; Humans; Mycobacterium tuberculosis; Phe | 2015 |
Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps.
Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Extensively Drug-Re | 2008 |
The broad-spectrum antimycobacterial activities of phenothiazines, InVitro: somewhere in all of this there may be patentable potentials.
Topics: Animals; Antitubercular Agents; Drug Discovery; Drug Resistance, Multiple, Bacterial; Drug Therapy, | 2011 |
New patentable use of an old neuroleptic compound thioridazine to combat tuberculosis: a gene regulation perspective.
Topics: Animals; Antitubercular Agents; Drug Discovery; Drug Resistance, Multiple, Bacterial; Drug Therapy, | 2011 |
Targeting the human macrophage with combinations of drugs and inhibitors of Ca2+ and K+ transport to enhance the killing of intracellular multi-drug resistant Mycobacterium tuberculosis (MDR-TB)--a novel, patentable approach to limit the emergence of XDR-
Topics: Animals; Antitubercular Agents; Calcium Signaling; Drug Discovery; Drug Resistance, Multiple, Bacter | 2011 |
Global clinical trials for the treatment of TB with thioridazine.
Topics: Antitubercular Agents; Clinical Trials as Topic; Drug Discovery; Drug Resistance, Multiple, Bacteria | 2011 |
"Non-Antibiotics": alternative therapy for the management of MDRTB and MRSA in economically disadvantaged countries.
Topics: Developing Countries; Humans; Methicillin Resistance; Staphylococcal Infections; Staphylococcus aure | 2006 |
Phenothiazines: potential alternatives for the management of antibiotic resistant infections of tuberculosis and malaria in developing countries.
Topics: Animals; Antimalarials; Antitubercular Agents; Developing Countries; Drug Resistance; Drug Resistanc | 2001 |
5 other studies available for thioridazine and Tuberculosis, Drug-Resistant
| Article | Year |
|---|---|
New US patent for potential treatment of multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Humans; Membrane Transport Proteins; Mycobacterium tuberc | 2014 |
Reduced emergence of isoniazid resistance with concurrent use of thioridazine against acute murine tuberculosis.
Topics: Animals; Antipsychotic Agents; Antitubercular Agents; Disease Models, Animal; Drug Repositioning; Dr | 2014 |
The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis.
Topics: Animals; Antipsychotic Agents; Antitubercular Agents; Disease Models, Animal; Drug Resistance, Bacte | 2010 |
It is anticipated that as is usually the case, financial motivation will move TZ from its current status “potential anti-MDR/XDR agent,” to one that will cure MDR and XDR TB. Foreword.
Topics: Animals; Antitubercular Agents; Drug Discovery; Drug Resistance, Multiple, Bacterial; Drug Therapy, | 2011 |
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Biological Transport, Active; Carrier Proteins; Catalase; | 2012 |