thioridazine has been researched along with Torsade de Pointes in 20 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of 82 year-old female with schizophrenia treated with thioridazine with a long QT syndrome and polymorphic ventricular tachycardia of torsade de pointes type was presented." | 7.73 | [Polymorphic ventricular tachycardia of torsade de pointes type in patient with schizophrenia treated with thioridazine]. ( Balak, W; Fares, I; Karasek, D; Małyszka, P; Papke, M; Sinkiewicz, W, 2006) |
| "Traditionally, torsade de pointes has been described in association with a congenital or acquired (including drug and metabolic) causes of QT prolongation." | 5.28 | [Iatrogenic torsade de pointes induced by thioridazine]. ( Blasi, N; Capone, P; Ciliberti, D; Paoloni, P, 1992) |
| "A case of 82 year-old female with schizophrenia treated with thioridazine with a long QT syndrome and polymorphic ventricular tachycardia of torsade de pointes type was presented." | 3.73 | [Polymorphic ventricular tachycardia of torsade de pointes type in patient with schizophrenia treated with thioridazine]. ( Balak, W; Fares, I; Karasek, D; Małyszka, P; Papke, M; Sinkiewicz, W, 2006) |
| "Torsades de pointes was originally seen in patients with pre-existing heart disease or with intoxication." | 2.42 | [Psychopharmaceuticals and arrhythmias]. ( Binggeli, C; Brunckhorst, C; Candinas, R, 2004) |
| "There was 1 case of torsade de pointes in a thioridazine overdose." | 1.42 | Prolonged QT Risk Assessment in Antipsychotic Overdose Using the QT Nomogram. ( Berling, I; Isbister, GK, 2015) |
| "Traditionally, torsade de pointes has been described in association with a congenital or acquired (including drug and metabolic) causes of QT prolongation." | 1.28 | [Iatrogenic torsade de pointes induced by thioridazine]. ( Blasi, N; Capone, P; Ciliberti, D; Paoloni, P, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (35.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pearlstein, R | 1 |
| Vaz, R | 1 |
| Rampe, D | 1 |
| Mirams, GR | 1 |
| Cui, Y | 1 |
| Sher, A | 1 |
| Fink, M | 1 |
| Cooper, J | 1 |
| Heath, BM | 1 |
| McMahon, NC | 1 |
| Gavaghan, DJ | 1 |
| Noble, D | 1 |
| Wiśniowska, B | 1 |
| Mendyk, A | 1 |
| Fijorek, K | 1 |
| Glinka, A | 1 |
| Polak, S | 1 |
| Kramer, J | 1 |
| Obejero-Paz, CA | 1 |
| Myatt, G | 1 |
| Kuryshev, YA | 1 |
| Bruening-Wright, A | 1 |
| Verducci, JS | 1 |
| Brown, AM | 1 |
| Berling, I | 1 |
| Isbister, GK | 1 |
| Sinkiewicz, W | 1 |
| Balak, W | 1 |
| Fares, I | 1 |
| Karasek, D | 1 |
| Małyszka, P | 1 |
| Papke, M | 1 |
| Roman, M | 1 |
| Farmer, SY | 1 |
| Zareba, W | 1 |
| Lin, DA | 1 |
| Binggeli, C | 1 |
| Candinas, R | 1 |
| Brunckhorst, C | 1 |
| Justo, D | 1 |
| Prokhorov, V | 1 |
| Heller, K | 1 |
| Zeltser, D | 1 |
| Schoenbaum, M | 1 |
| Näsh, O | 1 |
| Rydenhag, A | 1 |
| Liao, WB | 1 |
| Bullard, MJ | 1 |
| Kuo, CT | 1 |
| Hsiao, CT | 1 |
| Chu, PH | 1 |
| Chiang, CW | 1 |
| Denvir, MA | 1 |
| Sood, A | 1 |
| Dow, R | 1 |
| Brady, AJ | 1 |
| Rankin, AC | 1 |
| Su, KP | 1 |
| Chang, HC | 1 |
| Shen, WW | 1 |
| Paoloni, P | 1 |
| Ciliberti, D | 1 |
| Blasi, N | 1 |
| Capone, P | 1 |
| Quieffin, J | 1 |
| Brochet, E | 1 |
| Gamerman, G | 1 |
| Assayag, P | 1 |
| Antony, I | 1 |
| Valère, PE | 1 |
| Bastecký, J | 1 |
| Kvasnicka, J | 1 |
| Vortel, J | 1 |
| Zapletálek, M | 1 |
| Hanus, M | 1 |
| Kasparová, V | 1 |
| Wasylisová, V | 1 |
4 reviews available for thioridazine and Torsade de Pointes
| Article | Year |
|---|---|
Understanding the structure-activity relationship of the human ether-a-go-go-related gene cardiac K+ channel. A model for bad behavior.
Topics: Cation Transport Proteins; DNA-Binding Proteins; Drug-Related Side Effects and Adverse Reactions; ER | 2003 |
Antipsychotic drugs and QT interval prolongation.
Topics: Age Factors; Algorithms; Antipsychotic Agents; Benzodiazepines; Death, Sudden, Cardiac; Dopamine Ant | 2003 |
[Psychopharmaceuticals and arrhythmias].
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Arrhythmias, Cardiac; Dopamine Antagonists; | 2004 |
Torsade de pointes induced by psychotropic drugs and the prevalence of its risk factors.
Topics: Female; Haloperidol; Humans; Hypokalemia; Male; Mental Disorders; Prevalence; Psychotropic Drugs; Ri | 2005 |
16 other studies available for thioridazine and Torsade de Pointes
| Article | Year |
|---|---|
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; | 2011 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computationa | 2012 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp T | 2013 |
Prolonged QT Risk Assessment in Antipsychotic Overdose Using the QT Nomogram.
Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Drug Overdose; Electrocardiography; Fema | 2015 |
[Polymorphic ventricular tachycardia of torsade de pointes type in patient with schizophrenia treated with thioridazine].
Topics: Aged, 80 and over; Antipsychotic Agents; Electrocardiography; Female; Humans; Hypokalemia; Schizophr | 2006 |
Antipsychotic medications and cardiac conduction risks.
Topics: Antipsychotic Agents; Comorbidity; Death, Sudden, Cardiac; Electrocardiography; Heart Conduction Sys | 2010 |
Emergency: recognizing torsade de pointes.
Topics: Adult; Emergencies; Female; Humans; Thioridazine; Torsades de Pointes | 1995 |
[A case report. Torsades de pointes caused by overdose of thioridazine].
Topics: Diagnosis, Differential; Drug Overdose; Electrocardiography; Female; Humans; Middle Aged; Suicide, A | 1993 |
Anticholinergic overdose induced torsade de pointes successfully treated with verapamil.
Topics: Adolescent; Antidepressive Agents; Antipsychotic Agents; Cholinergic Antagonists; Drug Overdose; Fem | 1996 |
Thioridazine, diarrhoea and torsades de pointe.
Topics: Adult; Antipsychotic Agents; Diarrhea; Electrocardiography; Female; Humans; Middle Aged; Thioridazin | 1998 |
Warning on Mellaril.
Topics: Antipsychotic Agents; Humans; Thioridazine; Torsades de Pointes | 2000 |
Thioridazine and severe cardiac arrhythmia.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Contraindications; Drug Interactions; France; Schizophre | 2001 |
Prolongation of QTc interval and antipsychotics.
Topics: Antipsychotic Agents; Death, Sudden, Cardiac; Haloperidol; Humans; Long QT Syndrome; Thioridazine; T | 2002 |
[Iatrogenic torsade de pointes induced by thioridazine].
Topics: Cardiac Pacing, Artificial; Electrocardiography; Female; Humans; Iatrogenic Disease; Magnesium Sulfa | 1992 |
[Ventricular arrhythmia following thioridazine poisoning].
Topics: Amiodarone; Female; Humans; Middle Aged; Tachycardia; Thioridazine; Torsades de Pointes; Ventricular | 1991 |
[Suicidal ingestion of thioridazine as a cause of severe impairment of heart rhythm--polymorphic ventricular tachycardia].
Topics: Adult; Electrocardiography; Female; Humans; Suicide; Thioridazine; Torsades de Pointes | 1990 |