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thioridazine and Substance Withdrawal Syndrome

thioridazine has been researched along with Substance Withdrawal Syndrome in 51 studies

Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.

Research Excerpts

ExcerptRelevanceReference
"These three patients developed delirium with psychotic symptoms that resolved rapidly and completely upon resumption of low doses of clozapine."8.79Clozapine withdrawal resulting in delirium with psychosis: a report of three cases. ( de Leon, J; Simpson, GM; Stanilla, JK, 1997)
"These three patients developed delirium with psychotic symptoms that resolved rapidly and completely upon resumption of low doses of clozapine."4.79Clozapine withdrawal resulting in delirium with psychosis: a report of three cases. ( de Leon, J; Simpson, GM; Stanilla, JK, 1997)
"Thioridazine has little antiemetic action but perphenazine is prescribed for vomiting; hence it seems unlikely that the reported symptoms are due to a rebound action on the vomiting centre."1.24GASTROINTESTINAL DISTURBANCES ASSOCIATED WITH WITHDRAWAL OF ATARACTIC DRUGS. ( HADEN, P, 1964)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199043 (84.31)18.7374
1990's4 (7.84)18.2507
2000's3 (5.88)29.6817
2010's1 (1.96)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bastiampillai, T1
Fantasia, R1
Nelson, A1
Smith, C1
Felce, D1
Ahmed, Z1
Fraser, WI1
Kerr, M1
Kiernan, C1
Emerson, E1
Robertson, J1
Allen, D1
Baxter, H1
Thomas, J1
CAFFEY, EM1
DIAMOND, LS1
FRANK, TV1
GRASBERGER, JC1
HERMAN, L1
KLETT, CJ1
ROTHSTEIN, C1
HADEN, P1
PETERSEN, PB1
GANTZ, RS1
BIRKETT, DP1
Alevizos, B1
Ewart, RB1
Priest, RG1
Clow, A2
Theodorou, A2
Jenner, P2
Marsden, CD2
Faheem, AD1
Brightwell, DR1
Burton, GC1
Struss, A1
Breuning, SE1
Davis, VJ1
Matson, JL1
Ferguson, DG1
De Veaugh-Geiss, J1
Devanand, DP1
Carey, RJ1
Malas, KL1
van Kammen, DP1
Inoue, F1
Janikowski, AM1
Sovner, R1
May, P1
London, EB1
Zimmerman, T1
Thompson, R1
Mento, T1
Spreat, S1
Stanislav, SW1
Stanilla, JK1
de Leon, J1
Simpson, GM1
Davies, SJ1
Cooke, LB1
Moore, AG1
Potokar, J1
Davis, JM1
Gosenfeld, L1
Tsai, CC1
Baldino, F1
Cowan, A1
Geller, EB1
Adler, MW1
Kissin, B1
Gardos, G1
Pena-Ramos, A2
Hornberger, R1
Kumar, BB1
Thornton, WE1
Lacoursiere, R1
Laughren, TP1
Brown, WA1
Williams, BW1
Hague, WH1
Wilson, LG1
Dudley, DL1
Cannon, DS1
Yepes, LE1
Winsberg, BG1
Aman, MG1
Singh, NN1
Corrigan, FM1
Coulter, F1
Merriam, AE1
Böker, W1
Thaker, GK1
Alphs, L1
Tamminga, CA1
Klawans, HL1
Bergen, D1
Bruyn, GW1
Greenblatt, DJ1
Shader, RI1
Jus, A1
Pineau, R1
Jus, K1
Villeneuve, A1
Gautier, J1
Pires, P1
Drolet, A1
Cote, M1
Villeneuve, R1
Pozuelo, J1
Kerr, FW1
Oge, V1
McClelland, HA1
Blessed, G1
Bhate, S1
Ali, N1
Clarke, PA1
Masarik, J1
Mamoli, B1
Sydney, MA1
Newton, RW1
Crane, GE1
Naranjo, ER1
Krystof, J1
Zyg, J1
Mitkiewicz, S1
Kaczyński, J1
Gastager, H1
Abenson, MH1
Mulvaney, RB1

Reviews

4 reviews available for thioridazine and Substance Withdrawal Syndrome

ArticleYear
Clozapine withdrawal resulting in delirium with psychosis: a report of three cases.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:6

    Topics: Adult; Clozapine; Delirium; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule

1997
Discontinuation of thioridazine in patients with learning disabilities: balancing cardiovascular toxicity with adverse consequences of changing drugs.
    BMJ (Clinical research ed.), 2002, Jun-22, Volume: 324, Issue:7352

    Topics: Antipsychotic Agents; Humans; Learning Disabilities; Legislation, Drug; Risk Factors; Substance With

2002
Maintenance antipsychotic drugs do prevent relapse: a reply to Tobias and MacDonald.
    Psychological bulletin, 1976, Volume: 83, Issue:3

    Topics: Antipsychotic Agents; Chlorpromazine; Chronic Disease; Drug Evaluation; Fluphenazine; Humans; Perphe

1976
Drug therapy reviews: rational use of psychotropic drugs. III. Major tranquilizers.
    The Journal of the Maine Medical Association, 1974, Volume: 65, Issue:10

    Topics: Adrenergic alpha-Agonists; Adult; Alcoholism; Amphetamine; Antiemetics; Antipsychotic Agents; Body T

1974

Trials

5 trials available for thioridazine and Substance Withdrawal Syndrome

ArticleYear
MMPI and drug treatment in alcohol withdrawal.
    The Journal of clinical psychiatry, 1979, Volume: 40, Issue:8

    Topics: Adult; Alcoholism; Chlordiazepoxide; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Mid

1979
Post-detoxification drug treatment of anxiety and depression in alcohol addicts.
    The Journal of nervous and mental disease, 1976, Volume: 162, Issue:5

    Topics: Adult; Alcoholism; Anxiety; Clinical Trials as Topic; Depression; Humans; Male; Middle Aged; Psychia

1976
Penfluridol: a long-acting oral neuroleptic as therapeutic agent in chronic schizophrenia.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:10

    Topics: Adult; Analysis of Variance; Basal Ganglia Diseases; Body Weight; Chlorpromazine; Chronic Disease; C

1974
The abrupt withdrawal of antiparkinsonian drugs in schizophrenic patients.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 124, Issue:579

    Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Behavior; Chlorpromazine; Clinical Trials

1974
Motor disorders induced by neuroleptics: a proposed new classification.
    Archives of general psychiatry, 1971, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Dystonia Musculorum Deformans; Factor A

1971

Other Studies

42 other studies available for thioridazine and Substance Withdrawal Syndrome

ArticleYear
De novo treatment-resistant psychosis following thioridazine withdrawal.
    The Australian and New Zealand journal of psychiatry, 2014, Volume: 48, Issue:6

    Topics: Adult; Antipsychotic Agents; Humans; Male; Psychotic Disorders; Substance Withdrawal Syndrome; Thior

2014
Sedation effects on responsiveness: evaluating the reduction of antipsychotic medication in people with intellectual disability using a conditional probability approach.
    Journal of intellectual disability research : JIDR, 2002, Volume: 46, Issue:Pt 6

    Topics: Adult; Aged; Antipsychotic Agents; Behavior Therapy; Combined Modality Therapy; Drug Administration

2002
DISCONTINUATION OR REDUCTION OF CHEMOTHERAPY IN CHRONIC SCHIZOPHRENICS.
    Journal of chronic diseases, 1964, Volume: 17

    Topics: Behavior; Biomedical Research; Chlorpromazine; Humans; Placebos; Psychological Tests; Schizophrenia;

1964
GASTROINTESTINAL DISTURBANCES ASSOCIATED WITH WITHDRAWAL OF ATARACTIC DRUGS.
    Canadian Medical Association journal, 1964, Oct-31, Volume: 91

    Topics: Chlorpromazine; Chlorprothixene; Drug Therapy; Gastrointestinal Diseases; Mental Disorders; Perphena

1964
[WITHDRAWAL OF PSYCHOPHARMACA AND RELAPSE IN SCHIZOPHRENICS].
    Ugeskrift for laeger, 1964, Oct-08, Volume: 126

    Topics: Chlorprothixene; Chronic Disease; Humans; Paranoid Disorders; Perphenazine; Recurrence; Schizophreni

1964
PHENOTHIAZINE REDUCTION AS A CAUSE OF REHOSPITALIZATION.
    Archives of general psychiatry, 1965, Volume: 12

    Topics: Chlorpromazine; Drug Therapy; Fluphenazine; Hospitalization; Humans; Perphenazine; Phenothiazines; P

1965
Dependence and chronic psychosis with D-nor-pseudoephedrine.
    European psychiatry : the journal of the Association of European Psychiatrists, 2003, Volume: 18, Issue:8

    Topics: Antipsychotic Agents; Appetite; Appetite Depressants; Benzodiazepines; Central Nervous System Stimul

2003
Methaqualone addiction and delirium tremens.
    British medical journal, 1967, Jul-08, Volume: 3, Issue:5557

    Topics: Humans; Male; Methaqualone; Middle Aged; Paraldehyde; Phenobarbital; Promazine; Psychoses, Alcoholic

1967
Cerebral dopamine function in rats following withdrawal from one year of continuous neuroleptic administration.
    European journal of pharmacology, 1980, May-02, Volume: 63, Issue:2-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Bindi

1980
Respiratory dyskinesia and dysarthria from prolonged neuroleptic use: tardive dyskinesia?
    The American journal of psychiatry, 1982, Volume: 139, Issue:4

    Topics: Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dysarthria

1982
Effects of thioridazine and withdrawal dyskinesias on workshop performance of mentally retarded young adults.
    The American journal of psychiatry, 1982, Volume: 139, Issue:11

    Topics: Adolescent; Adult; Dyskinesia, Drug-Induced; Female; Humans; Intellectual Disability; Male; Motor Sk

1982
Differential liabilities of haloperidol and thioridazine for inducing apomorphine hypersensitivity.
    Biological psychiatry, 1982, Volume: 17, Issue:11

    Topics: Animals; Apomorphine; Benztropine; Corpus Striatum; Dose-Response Relationship, Drug; Haloperidol; H

1982
Markedly elevated creatine phosphokinase levels after neuroleptic withdrawal.
    The American journal of psychiatry, 1982, Volume: 139, Issue:2

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Creatine Kinase; Double-Blind Method; Dysk

1982
Changes in cerebral dopamine function induced by a year's administration of trifluoperazine or thioridazine and their subsequent withdrawal.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Brain; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced;

1980
Withdrawal akinesia.
    Journal of neurology, neurosurgery, and psychiatry, 1981, Volume: 44, Issue:10

    Topics: Basal Ganglia Diseases; Chlorpromazine; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; Th

1981
Thioridazine withdrawal-induced behavioral deterioration treated with clonidine: two case reports.
    Mental retardation, 1995, Volume: 33, Issue:4

    Topics: Administration, Cutaneous; Anxiety Disorders; Bipolar Disorder; Clonidine; Dose-Response Relationshi

1995
A study of the clinical outcome of patients with profound mental retardation gradually withdrawn from chronic neuroleptic medication.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1995, Volume: 7, Issue:4

    Topics: Adult; Antipsychotic Agents; Diagnosis, Differential; Dose-Response Relationship, Drug; Epilepsy; Hu

1995
Cognitive effects of antipsychotic agents in persons with traumatic brain injury.
    Brain injury, 1997, Volume: 11, Issue:5

    Topics: Adult; Antipsychotic Agents; Brain Damage, Chronic; Brain Injuries; Cognition Disorders; Haloperidol

1997
Effects of antipsychotic and antianxiety drugs on the morphine abstinence syndrome in rats.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Body Weight; Chlordiazepoxide;

1979
The use of psychoactive drugs in the long-term treatment of chronic alcoholics.
    Annals of the New York Academy of Sciences, 1975, Apr-25, Volume: 252

    Topics: Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Ch

1975
A case of withdrawal dyskinesia.
    The American journal of psychiatry, 1979, Volume: 136, Issue:8

    Topics: Benztropine; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Imipramine; Middle Aged; S

1979
Thioridazine, drug holidays, and incidence of vomiting.
    JAMA, 1978, Jan-02, Volume: 239, Issue:1

    Topics: Humans; Mental Disorders; Substance Withdrawal Syndrome; Thioridazine

1978
Alcohol withdrawal and thioridazine.
    Diseases of the nervous system, 1977, Volume: 38, Issue:12

    Topics: Alcoholism; Arrhythmias, Cardiac; Humans; Substance Withdrawal Syndrome; Thioridazine

1977
Medical effects of abrupt withdrawal of neuroleptic therapy.
    JAMA, 1978, Jul-14, Volume: 240, Issue:2

    Topics: Humans; Nausea; Substance Withdrawal Syndrome; Thioridazine; Vomiting

1978
Serum prolactin and clinical state during neuroleptic treatment and withdrawal.
    The American journal of psychiatry, 1979, Volume: 136, Issue:1

    Topics: Adult; Alcoholism; Haloperidol; Humans; Hysteria; Male; Middle Aged; Prolactin; Psychiatric Status R

1979
Thioridazine HC1 Vs. chlordiazepoxide HC1 in controlling symptoms attributable to alcohol withdrawal.
    Diseases of the nervous system, 1977, Volume: 38, Issue:3

    Topics: Adult; Aged; Alcoholism; Chlordiazepoxide; Drug Evaluation; Female; Humans; Male; Middle Aged; Psych

1977
Vomiting during neuroleptic withdrawal in children.
    The American journal of psychiatry, 1977, Volume: 134, Issue:5

    Topics: Child; Chlorprothixene; Dyskinesia, Drug-Induced; Humans; Male; Substance Withdrawal Syndrome; Thior

1977
A critical appraisal of recent drug research in mental retardation: the Coldwater studies.
    Journal of mental deficiency research, 1986, Volume: 30 ( Pt 3)

    Topics: Aggression; Antipsychotic Agents; Attitude of Health Personnel; Discrimination Learning; Humans; Ins

1986
Neuroleptic malignant syndrome, amitriptyline, and thioridazine.
    Biological psychiatry, 1988, Feb-01, Volume: 23, Issue:3

    Topics: Amitriptyline; Humans; Male; Middle Aged; Neuroleptic Malignant Syndrome; Substance Withdrawal Syndr

1988
Withdrawal NMS after drug treatment.
    Biological psychiatry, 1988, Volume: 24, Issue:3

    Topics: Amitriptyline; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Neuroleptic Malignant Syn

1988
[Steps in the recovery from severe depression. On the psychosomatic aspects of a convalescent process].
    Psychiatrische Praxis, 1986, Volume: 13, Issue:2

    Topics: Adaptation, Psychological; Adjustment Disorders; Anxiety Disorders; Convalescence; Depressive Disord

1986
Labile hypertension after antipsychotic drug withdrawal: a case report.
    Biological psychiatry, 1985, Volume: 20, Issue:11

    Topics: Humans; Hypertension; Male; Middle Aged; Substance Withdrawal Syndrome; Thioridazine

1985
Prolonged drug-induced Parkinsonism.
    Confinia neurologica, 1973, Volume: 35, Issue:6

    Topics: Adult; Antipsychotic Agents; Female; Humans; Middle Aged; Parkinson Disease, Secondary; Prochlorpera

1973
Suppression of craving and other signs of dependence in morphine-addicted monkeys by administration of alpha-methyl-para-tyrosine.
    Mayo Clinic proceedings, 1972, Volume: 47, Issue:9

    Topics: Animals; Female; Fenclonine; Haloperidol; Haplorhini; Humans; Hypothalamus; Injections, Intravenous;

1972
Drug therapy in alcoholism. It is especially important in the prevention of such complications as seizures, DT's, Wernicke's encephalopathy, or polyneuritis.
    IMJ. Illinois medical journal, 1971, Volume: 139, Issue:6

    Topics: Alcoholism; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Diazepam; Disulfiram; Humans; Hydroxy

1971
[Experiences with thioridazine in the treatment of withdrawal symptoms in alcoholics].
    Wiener medizinische Wochenschrift (1946), 1973, Aug-04, Volume: 123, Issue:31

    Topics: Alcoholism; Ambulatory Care; Chronic Disease; Humans; Substance Withdrawal Syndrome; Thioridazine

1973
Ventricular arrhythmias associated with use of thioridazine hydrochloride in alcohol withdrawal.
    British medical journal, 1973, Nov-24, Volume: 4, Issue:5890

    Topics: Adult; Alcoholism; Electrocardiography; Female; Humans; Male; Potassium; Potassium Deficiency; Subst

1973
Letter: Ventricular dysrhythmias and thioridazine in alcohol withdrawal.
    British medical journal, 1973, Dec-22, Volume: 4, Issue:5894

    Topics: Alcoholism; Arrhythmias, Cardiac; Electrocardiography; Humans; Hypokalemia; Substance Withdrawal Syn

1973
Withdrawal symptoms after long-term treatment with neuroleptics.
    Polish medical journal, 1972, Volume: 11, Issue:1

    Topics: Adult; Aged; Blood Circulation; Chlorpromazine; Fever; Humans; Hyperkinesis; Hypotension; Hypothermi

1972
Chlormethiazole treatment of abstinence symptoms after drug withdrawal. Preliminary reports. 3.
    Acta psychiatrica Scandinavica. Supplementum, 1966, Volume: 192

    Topics: Alcoholism; Barbiturates; Chlormethiazole; Humans; Hypnotics and Sedatives; Male; Meprobamate; Subst

1966
Drug withdrawal in male and female chronic schizophrenics.
    The British journal of psychiatry : the journal of mental science, 1969, Volume: 115, Issue:525

    Topics: Chlorpromazine; Chronic Disease; Cognition Disorders; Female; Humans; Male; Paranoid Disorders; Phen

1969
Treatment of narcotic withdrawal symptoms with thioridazine.
    Diseases of the nervous system, 1966, Volume: 27, Issue:5

    Topics: Adult; Humans; Male; Narcotics; Substance Withdrawal Syndrome; Substance-Related Disorders; Thiorida

1966