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thioridazine and Neuroleptic Malignant Syndrome

thioridazine has been researched along with Neuroleptic Malignant Syndrome in 20 studies

Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)

Research Excerpts

ExcerptRelevanceReference
"We report a fulminant case of Neuroleptic Malignant Syndrome in a 31-year-old male schizophrenic on haloperidol, thioridazine, benzhexol and flurazepam who presented with rigidity, fever, stupor and autonomic instability."3.69A fulminant case of neuroleptic malignant syndrome. ( Chew, WL; Lam, KN; Teo, SK, 1994)
" He developed neuroleptic malignant syndrome (NMS) which was treated successfully with intravenous diazepam."3.69Catatonic syndrome following recovery from neuroleptic malignant syndrome. ( Dent, J, 1995)
"Two cases are presented in which psychotic patients with neuroleptic malignant syndrome were treated with bromocriptine and thioridazine simultaneously, with a resulting control of both problems."3.67Concomitant treatment of neuroleptic malignant syndrome and psychosis. ( Goldwasser, HD; Hooper, JF; Spears, NM, 1989)
"To report a case of neuroleptic malignant syndrome (NMS) in a child, and review reports of 11 other paediatric cases of NMS."1.28Neuroleptic malignant syndrome in children. ( Numa, A, 1991)
"Two patients with primary hypothyroidism who developed neuroleptic malignant syndrome (NMS) are described."1.28Neuroleptic malignant syndrome and hypothyroidism. ( Blumhardt, LD; Macfarlane, IA; Moore, AP, 1990)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's11 (55.00)18.2507
2000's2 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Imbach, M1
Hess, Ch1
Froesch, T1
Yildiz, A1
Alkin, T1
Ozerdem, A1
Sagduyu, K1
Demopulos, CM1
Nimmo, SM1
Kennedy, BW1
Tullett, WM1
Blyth, AS1
Dougall, JR1
Teo, SK1
Lam, KN1
Chew, WL1
Dent, J1
Freedman, MD1
Rao, KA1
Adlakha, A1
Meloy, T1
Numa, A1
Lazarus, A1
Rosenberg, H1
Teglia, MQ1
Hopkins, TT1
Cunha, BA1
Kassirer, JP1
Kopelman, RI1
Kasckow, J1
Dolor, R1
Lipper, S1
Moore, AP1
Macfarlane, IA1
Blumhardt, LD1
Moysa, GD1
Anisete, LV1
Goldwasser, HD1
Hooper, JF1
Spears, NM1
Aizenberg, D1
Shalev, A1
Munitz, H1
Corrigan, FM1
Coulter, F1
Merriam, AE1
Zammit, GK1
Sullivan, TB1
Chin, CN1

Reviews

1 review available for thioridazine and Neuroleptic Malignant Syndrome

ArticleYear
Neuroleptic malignant syndrome and acute myocardial infarction: case report and review.
    Maryland medical journal (Baltimore, Md. : 1985), 1997, Volume: 46, Issue:7

    Topics: Antipsychotic Agents; Bromocriptine; Dopamine Agonists; Humans; Male; Middle Aged; Myocardial Infarc

1997

Other Studies

19 other studies available for thioridazine and Neuroleptic Malignant Syndrome

ArticleYear
[Uncertain neurological status in a depressed patient].
    Praxis, 2002, Jun-19, Volume: 91, Issue:25-26

    Topics: Aged; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder; Drug Therapy, Combination; H

2002
Neuroleptic malignant syndrome: a case that may shed new light into the etiology and treatment.
    The Australian and New Zealand journal of psychiatry, 2003, Volume: 37, Issue:4

    Topics: Acute-Phase Proteins; Adult; Antipsychotic Agents; Bromocriptine; Clopenthixol; Dopamine Agonists; E

2003
Drug-induced hyperthermia.
    Anaesthesia, 1993, Volume: 48, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Female; Fluoxetine; Humans; Male; Middle Aged;

1993
A fulminant case of neuroleptic malignant syndrome.
    Singapore medical journal, 1994, Volume: 35, Issue:1

    Topics: Adult; Drug Therapy, Combination; Fatal Outcome; Haloperidol; Humans; Male; Neuroleptic Malignant Sy

1994
Catatonic syndrome following recovery from neuroleptic malignant syndrome.
    Journal of intellectual disability research : JIDR, 1995, Volume: 39 ( Pt 5)

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Catatonia; Chlorpromazine; Diazepam; Dose-Response Relati

1995
Tremor, confusion, and autonomic dysfunction in Down syndrome.
    Hospital practice (Office ed.), 1992, Aug-15, Volume: 27, Issue:8

    Topics: Adult; Autonomic Nervous System Diseases; Confusion; Diagnosis, Differential; Down Syndrome; Haloper

1992
Neuroleptic malignant syndrome in children.
    The Medical journal of Australia, 1991, Sep-16, Volume: 155, Issue:6

    Topics: Child; Humans; Male; Neuroleptic Malignant Syndrome; Thioridazine

1991
Treatment of rehospitalized NMS patients.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:2

    Topics: Adult; Antipsychotic Agents; Fluphenazine; Follow-Up Studies; Humans; Male; Neuroleptic Malignant Sy

1990
Neuroleptic malignant syndrome and Escherichia coli urosepsis.
    Heart & lung : the journal of critical care, 1991, Volume: 20, Issue:2

    Topics: Aged; Aged, 80 and over; Escherichia coli Infections; Humans; Incidence; Male; Neuroleptic Malignant

1991
The accuracy of clinical information. 1. The history.
    Hospital practice (Office ed.), 1991, Apr-15, Volume: 26, Issue:4

    Topics: Adult; Female; Humans; Kidney Tubular Necrosis, Acute; Medical History Taking; Neuroleptic Malignant

1991
Delayed onset of neuroleptic malignant syndrome after discontinuation of thioridazine.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:2

    Topics: Humans; Male; Middle Aged; Neuroleptic Malignant Syndrome; Thioridazine; Time Factors

1990
Neuroleptic malignant syndrome and hypothyroidism.
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:6

    Topics: Adult; Brain; Female; Humans; Hypothyroidism; Middle Aged; Neuroleptic Malignant Syndrome; Obsessive

1990
Neuroleptic malignant syndrome: successful rechallenge with thioridazine.
    DICP : the annals of pharmacotherapy, 1989, Volume: 23, Issue:9

    Topics: Adult; Antipsychotic Agents; Humans; Male; Neuroleptic Malignant Syndrome; Schizophrenia; Thioridazi

1989
Concomitant treatment of neuroleptic malignant syndrome and psychosis.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 154

    Topics: Adult; Bromocriptine; Creatine Kinase; Humans; Male; Neuroleptic Malignant Syndrome; Psychotic Disor

1989
The aftercare of the patient with the neuroleptic malignant syndrome.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 146

    Topics: Adult; Aftercare; Basal Ganglia Diseases; Electroconvulsive Therapy; Humans; Male; Methotrimeprazine

1985
Neuroleptic malignant syndrome, amitriptyline, and thioridazine.
    Biological psychiatry, 1988, Feb-01, Volume: 23, Issue:3

    Topics: Amitriptyline; Humans; Male; Middle Aged; Neuroleptic Malignant Syndrome; Substance Withdrawal Syndr

1988
Withdrawal NMS after drug treatment.
    Biological psychiatry, 1988, Volume: 24, Issue:3

    Topics: Amitriptyline; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Neuroleptic Malignant Syn

1988
Thioridazine and neuroleptic malignant syndrome.
    Biological psychiatry, 1987, Volume: 22, Issue:10

    Topics: Female; Humans; Neuroleptic Malignant Syndrome; Thioridazine

1987
Neuroleptic malignant syndrome: a case report.
    The Medical journal of Malaysia, 1986, Volume: 41, Issue:2

    Topics: Aged; Dementia; Drug Therapy, Combination; Female; Humans; Neuroleptic Malignant Syndrome; Thioridaz

1986