thioridazine has been researched along with Muscle Rigidity in 3 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A paranoid schizophrenic patient developed the neuroleptic malignant syndrome after receiving three doses of fluphenazine HCl and two doses of thioridazine while he was recovering from major trauma." | 7.66 | A case of neuroleptic malignant syndrome successfully treated with amantadine. ( Boettger, ML; McCarron, MM; Peck, JJ, 1982) |
| " Muscle rigidity was assessed quantitatively and objectively as increases in electromyographic (EMG) activity (muscle rigidity) in the hindlimb muscles of the rat following subcutaneous administration of haloperidol, fluphenazine and thioridazine." | 3.71 | An animal model of extrapyramidal side effects induced by antipsychotic drugs: relationship with D2 dopamine receptor occupancy. ( Crocker, AD; Hemsley, KM, 2001) |
| "A paranoid schizophrenic patient developed the neuroleptic malignant syndrome after receiving three doses of fluphenazine HCl and two doses of thioridazine while he was recovering from major trauma." | 3.66 | A case of neuroleptic malignant syndrome successfully treated with amantadine. ( Boettger, ML; McCarron, MM; Peck, JJ, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCarron, MM | 1 |
| Boettger, ML | 1 |
| Peck, JJ | 1 |
| Crocker, AD | 1 |
| Hemsley, KM | 1 |
| McClelland, HA | 1 |
| Blessed, G | 1 |
| Bhate, S | 1 |
| Ali, N | 1 |
| Clarke, PA | 1 |
1 trial available for thioridazine and Muscle Rigidity
| Article | Year |
|---|---|
The abrupt withdrawal of antiparkinsonian drugs in schizophrenic patients.
Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Behavior; Chlorpromazine; Clinical Trials | 1974 |
2 other studies available for thioridazine and Muscle Rigidity
| Article | Year |
|---|---|
A case of neuroleptic malignant syndrome successfully treated with amantadine.
Topics: Adult; Amantadine; Consciousness Disorders; Fluphenazine; Humans; Male; Malignant Hyperthermia; Musc | 1982 |
An animal model of extrapyramidal side effects induced by antipsychotic drugs: relationship with D2 dopamine receptor occupancy.
Topics: Animals; Antipsychotic Agents; Catalepsy; Corpus Striatum; Disease Models, Animal; Dose-Response Rel | 2001 |