Page last updated: 2024-11-05

thioridazine and Muscle Contraction

thioridazine has been researched along with Muscle Contraction in 15 studies

Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Thioridazine did not inhibit the lengthening response."1.28Effects of thioridazine on mechanical responses of human vas deferens induced by noradrenaline or potassium. ( Amobi, NI; Smith, IC, 1992)
" Dose-response curves were established for the blockade of ICSS by the antipsychotic drugs chlorpromazine, thioridazine, clozapine, and pimozide and the alpha-antagonist phenoxybenzamine."1.26Blockade of intracranial self-stimulation by antipsychotic drugs: failure to correlate with central alpha-noradrenergic blockade. ( Setler, P; Weidley, E; Zarevics, P, 1977)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199012 (80.00)18.7374
1990's2 (13.33)18.2507
2000's1 (6.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mousavizadeh, K1
Ghafourifar, P1
Sadeghi-Nejad, H1
Feigen, GA1
Sanz, E1
Alender, CB1
Gould, RJ1
Murphy, KM1
Reynolds, IJ1
Snyder, SH1
Downes, H1
Gourley, LA1
Kloka, AC1
Zarevics, P1
Weidley, E1
Setler, P1
Nakanishi, H1
Kaneko, M1
Latimer, PR1
Braden, DH1
Amobi, NI1
Smith, IC2
Amobi, N1
Landmark, K5
Haffner, JF2
Setekleiv, J2
Hollander, PB1
Cain, RM1

Other Studies

15 other studies available for thioridazine and Muscle Contraction

ArticleYear
Calcium channel blocking activity of thioridazine, clomipramine and fluoxetine in isolated rat vas deferens: a relative potency measurement study.
    The Journal of urology, 2002, Volume: 168, Issue:6

    Topics: Animals; Antidepressive Agents; Calcium; Calcium Channel Blockers; Clomipramine; Dose-Response Relat

2002
Studies on the mode of action of sea urchin toxin. I. Conditions affecting release of hiamine and other agents from isolated tissues.
    Toxicon : official journal of the International Society on Toxinology, 1966, Volume: 4, Issue:3

    Topics: Animals; Atropine; Blood Flow Velocity; Carbon; Chemical Precipitation; Chemistry Techniques, Analyt

1966
Calcium channel blockade: possible explanation for thioridazine's peripheral side effects.
    The American journal of psychiatry, 1984, Volume: 141, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Ejaculation; Female; Ion Channels; Male; Mu

1984
Influence of extracellular calcium on extent of thioridazine induced alpha-adrenergic block in rabbit aortic strips.
    Proceedings of the Western Pharmacology Society, 1977, Volume: 20

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Blood Vessels; Calcium; Drug Interactions; In Vitro Te

1977
Blockade of intracranial self-stimulation by antipsychotic drugs: failure to correlate with central alpha-noradrenergic blockade.
    Psychopharmacology, 1977, Aug-16, Volume: 53, Issue:3

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Depression, Chemical; Electric Stimulation

1977
Is thioridazine-induced ejaculation failure peripheral in origin?
    Research communications in chemical pathology and pharmacology, 1978, Volume: 19, Issue:3

    Topics: Animals; Chlorpromazine; Depression, Chemical; Ejaculation; Electric Stimulation; In Vitro Technique

1978
Roussy-Levy Syndrome with psychosis.
    Canadian Psychiatric Association journal, 1975, Volume: 20, Issue:4

    Topics: Adult; Female; Humans; Movement Disorders; Muscle Contraction; Paranoid Disorders; Perceptual Disord

1975
Effects of thioridazine on mechanical responses of human vas deferens induced by noradrenaline or potassium.
    Journal of reproduction and fertility, 1992, Volume: 95, Issue:1

    Topics: Culture Techniques; Diltiazem; Humans; Male; Muscle Contraction; Norepinephrine; Phentolamine; Potas

1992
Paradoxical effects of thioridazine on electromechanical coupling in the human and rat vas deferens.
    European journal of pharmacology, 1991, Jan-17, Volume: 192, Issue:3

    Topics: Animals; Biomechanical Phenomena; Caffeine; Calcimycin; Calcium Channel Blockers; Humans; In Vitro T

1991
The action of promazine and thioridazine in isolated rat atria. 2. Effects of varying concentrations of potassium and sodium on automaticity, mechanical performance, refractoriness and excitability.
    European journal of pharmacology, 1972, Volume: 17, Issue:1

    Topics: Animals; Atropine; Depression, Chemical; Electric Stimulation; Female; Heart Atria; In Vitro Techniq

1972
The action of promazine and thioridazine in isolated rat atria. 3. Effects of varying concentrations of calcium and different frequencies and strengths of stimulation on contractile force and excitability.
    European journal of pharmacology, 1972, Volume: 17, Issue:3

    Topics: Acetanilides; Amino Alcohols; Animals; Atropine; Calcium; Electric Stimulation; Heart Atria; In Vitr

1972
Reduction in 42 K-efflux from rat atria by promazine and thioridazine.
    Acta pharmacologica et toxicologica, 1972, Volume: 31, Issue:1

    Topics: Acid-Base Equilibrium; Animals; Cell Membrane; Cell Membrane Permeability; Electric Stimulation; Ele

1972
The action of promazine and thioridazine in isolated rat atria. 1. Effects on automaticity, mechanical performance, refractoriness and excitability.
    European journal of pharmacology, 1971, Volume: 16, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Electric Stimulation; Female; Heart Arrest; Hear

1971
Effects of thioridazine on transmembrane potential and contractile characteristics of guinea pig hearts.
    European journal of pharmacology, 1971, Volume: 16, Issue:2

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Electric Stimulation; Electrophysiology; Guinea Pi

1971
Phenothiazine-induced reduction in 42-K efflux from isolated, electrically stimulated rat atria.
    Acta pharmacologica et toxicologica, 1970, Volume: 28, Issue:1

    Topics: Animals; Heart Atria; In Vitro Techniques; Muscle Contraction; Myocardium; Potassium; Potassium Isot

1970