Page last updated: 2024-11-05

thioridazine and Latent Tuberculosis

thioridazine has been researched along with Latent Tuberculosis in 3 studies

Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

Latent Tuberculosis: The dormant form of TUBERCULOSIS where the person shows no obvious symptoms and no sign of the causative agent (Mycobacterium tuberculosis) in the SPUTUM despite being positive for tuberculosis infection skin test.

Research Excerpts

ExcerptRelevanceReference
"Models have been developed to study latent tuberculosis with the two most prominent being the in vivo murine model and the in vitro Wayne model."6.47Latent tuberculosis: is there a role for thioridazine? ( Sohaskey, C, 2011)
"Further, a murine model of latent tuberculosis was used and the standard 9-month isoniazid and 4-month rifampicin regimen along with thioridazine as an adjunct drug were evaluated."5.40Chemotherapeutic efficacy of thioridazine as an adjunct drug in a murine model of latent tuberculosis. ( Sharma, S; Singh, A, 2014)
"Further, a murine model of latent tuberculosis was used and the standard 9-month isoniazid and 4-month rifampicin regimen along with thioridazine as an adjunct drug were evaluated."1.40Chemotherapeutic efficacy of thioridazine as an adjunct drug in a murine model of latent tuberculosis. ( Sharma, S; Singh, A, 2014)
"This thioridazine exposure was calculated to extinguish all three M."1.39Thioridazine pharmacokinetic-pharmacodynamic parameters "Wobble" during treatment of tuberculosis: a theoretical basis for shorter-duration curative monotherapy with congeners. ( Gumbo, T; Leff, R; Meek, C; Musuka, S; Pasipanodya, J; Siyambalapitiyage Dona, CW; Srivastava, S, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Musuka, S1
Srivastava, S1
Siyambalapitiyage Dona, CW1
Meek, C1
Leff, R1
Pasipanodya, J1
Gumbo, T1
Singh, A1
Sharma, S1
Sohaskey, C1

Reviews

1 review available for thioridazine and Latent Tuberculosis

ArticleYear
Latent tuberculosis: is there a role for thioridazine?
    Recent patents on anti-infective drug discovery, 2011, Volume: 6, Issue:2

    Topics: Animals; Antitubercular Agents; Drug Discovery; Drug Resistance, Multiple, Bacterial; Drug Therapy,

2011

Other Studies

2 other studies available for thioridazine and Latent Tuberculosis

ArticleYear
Thioridazine pharmacokinetic-pharmacodynamic parameters "Wobble" during treatment of tuberculosis: a theoretical basis for shorter-duration curative monotherapy with congeners.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12

    Topics: Antipsychotic Agents; Antitubercular Agents; Colony Count, Microbial; Computer Simulation; Drug Admi

2013
Chemotherapeutic efficacy of thioridazine as an adjunct drug in a murine model of latent tuberculosis.
    Tuberculosis (Edinburgh, Scotland), 2014, Volume: 94, Issue:6

    Topics: Animals; Antitubercular Agents; Colony Count, Microbial; Disease Models, Animal; Dose-Response Relat

2014