thioridazine has been researched along with Glial Cell Tumors in 5 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " screen phenothiazines for cytotoxic activity in glioma, neuroblastoma, and primary mouse brain tissue; and (2)." | 7.72 | Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors. ( Dayag, M; Gil-Ad, I; Levkovitz, Y; Shtaif, B; Weizman, A; Zeldich, E, 2004) |
| "Thioridazine (THD) is a common phenothiazine antipsychotic drug reported to suppress growth in several types of cancer cells." | 5.51 | Thioridazine Enhances P62-Mediated Autophagy and Apoptosis Through Wnt/β-Catenin Signaling Pathway in Glioma Cells. ( Cheng, HW; Cheng, JT; Cheng, TS; Chiou, SJ; Chou, CH; Chu, CW; Hong, YR; Huang, CF; Ko, HJ; Lai, YL; Liang, YH; Lin, CY; Loh, JK; Su, CL; Wang, C, 2019) |
| " screen phenothiazines for cytotoxic activity in glioma, neuroblastoma, and primary mouse brain tissue; and (2)." | 3.72 | Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors. ( Dayag, M; Gil-Ad, I; Levkovitz, Y; Shtaif, B; Weizman, A; Zeldich, E, 2004) |
| "Thioridazine (THD) is a common phenothiazine antipsychotic drug reported to suppress growth in several types of cancer cells." | 1.51 | Thioridazine Enhances P62-Mediated Autophagy and Apoptosis Through Wnt/β-Catenin Signaling Pathway in Glioma Cells. ( Cheng, HW; Cheng, JT; Cheng, TS; Chiou, SJ; Chou, CH; Chu, CW; Hong, YR; Huang, CF; Ko, HJ; Lai, YL; Liang, YH; Lin, CY; Loh, JK; Su, CL; Wang, C, 2019) |
| "Thioridazine has been known as an antipsychotic agent, but it also has anticancer activity." | 1.40 | Antipsychotic agent thioridazine sensitizes renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated inhibition of Akt signaling and downregulation of Mcl-1 and c-FLIP(L). ( Bae, YC; Kwon, TK; Min, KJ; Seo, BR; Yoo, YH, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chu, CW | 1 |
| Ko, HJ | 1 |
| Chou, CH | 1 |
| Cheng, TS | 1 |
| Cheng, HW | 1 |
| Liang, YH | 1 |
| Lai, YL | 1 |
| Lin, CY | 1 |
| Wang, C | 1 |
| Loh, JK | 1 |
| Cheng, JT | 1 |
| Chiou, SJ | 1 |
| Su, CL | 1 |
| Huang, CF | 1 |
| Hong, YR | 1 |
| Min, KJ | 2 |
| Seo, BR | 1 |
| Bae, YC | 1 |
| Yoo, YH | 1 |
| Kwon, TK | 2 |
| Seo, SU | 1 |
| Cho, HK | 1 |
| Woo, SM | 1 |
| Kim, S | 1 |
| Park, JW | 1 |
| Kim, SH | 1 |
| Choi, YH | 1 |
| Keum, YS | 1 |
| Hyun, JW | 1 |
| Park, HH | 1 |
| Lee, SH | 1 |
| Kim, DE | 1 |
| Gil-Ad, I | 1 |
| Shtaif, B | 1 |
| Levkovitz, Y | 1 |
| Dayag, M | 1 |
| Zeldich, E | 1 |
| Weizman, A | 1 |
| Sundberg, AL | 1 |
| Steffen, AC | 1 |
5 other studies available for thioridazine and Glial Cell Tumors
| Article | Year |
|---|---|
Thioridazine Enhances P62-Mediated Autophagy and Apoptosis Through Wnt/β-Catenin Signaling Pathway in Glioma Cells.
Topics: Apoptosis; Autophagy; Beclin-1; Blotting, Western; Catenins; Cell Cycle; Cell Line, Tumor; Cell Surv | 2019 |
Antipsychotic agent thioridazine sensitizes renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated inhibition of Akt signaling and downregulation of Mcl-1 and c-FLIP(L).
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antipsychotic Agents; Apoptos | 2014 |
Thioridazine enhances sensitivity to carboplatin in human head and neck cancer cells through downregulation of c-FLIP and Mcl-1 expression.
Topics: Breast Neoplasms; Carboplatin; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line; Cell Lin | 2017 |
Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Calmodulin; Caspase 3; Caspases; Cell Di | 2004 |
Enhancing the effect of radionuclide tumor targeting, using lysosomotropic weak bases.
Topics: Amantadine; Ammonium Chloride; Antimalarials; Antipsychotic Agents; Antiviral Agents; Astatine; Carc | 2007 |