thioridazine has been researched along with Electrocardiogram QT Prolonged in 21 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Torsades de pointes was originally seen in patients with pre-existing heart disease or with intoxication." | 2.42 | [Psychopharmaceuticals and arrhythmias]. ( Binggeli, C; Brunckhorst, C; Candinas, R, 2004) |
| "There was 1 case of torsade de pointes in a thioridazine overdose." | 1.42 | Prolonged QT Risk Assessment in Antipsychotic Overdose Using the QT Nomogram. ( Berling, I; Isbister, GK, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 19 (90.48) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kongsamut, S | 1 |
| Kang, J | 1 |
| Chen, XL | 1 |
| Roehr, J | 1 |
| Rampe, D | 2 |
| Cavalli, A | 1 |
| Poluzzi, E | 1 |
| De Ponti, F | 1 |
| Recanatini, M | 1 |
| Pearlstein, R | 1 |
| Vaz, R | 1 |
| Berling, I | 1 |
| Isbister, GK | 1 |
| Roman, M | 1 |
| Farmer, SY | 1 |
| Menkes, DB | 1 |
| Knight, JC | 1 |
| LLerena, A | 1 |
| Berecz, R | 1 |
| de la Rubia, A | 1 |
| Dorado, P | 1 |
| Laisalmi, M | 1 |
| Brahm, NC | 1 |
| Buswell, A | 1 |
| Christensen, D | 1 |
| Brown, RD | 1 |
| Zareba, W | 1 |
| Lin, DA | 1 |
| Timell, AM | 1 |
| Harrigan, EP | 1 |
| Miceli, JJ | 1 |
| Anziano, R | 1 |
| Watsky, E | 1 |
| Reeves, KR | 1 |
| Cutler, NR | 1 |
| Sramek, J | 1 |
| Shiovitz, T | 1 |
| Middle, M | 1 |
| Wright, NM | 1 |
| Roberts, AJ | 1 |
| Allgar, VL | 1 |
| Tompkins, CN | 1 |
| Greenwood, DC | 1 |
| Laurence, G | 1 |
| Binggeli, C | 1 |
| Candinas, R | 1 |
| Brunckhorst, C | 1 |
| Shiotani, M | 1 |
| Harada, T | 1 |
| Abe, J | 1 |
| Sawada, Y | 1 |
| Hashimoto, K | 1 |
| Hamada, Y | 1 |
| Horii, I | 1 |
| Salih, IS | 1 |
| Thanacoody, RH | 2 |
| McKay, GA | 1 |
| Thomas, SH | 2 |
| Daly, AK | 1 |
| Reilly, JG | 1 |
| Ferrier, IN | 1 |
| Hancox, JC | 1 |
| Witchel, HJ | 1 |
| Dallaire, S | 1 |
| Sachdev, P | 1 |
| Su, KP | 1 |
| Chang, HC | 1 |
| Shen, WW | 1 |
4 reviews available for thioridazine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Understanding the structure-activity relationship of the human ether-a-go-go-related gene cardiac K+ channel. A model for bad behavior.
Topics: Cation Transport Proteins; DNA-Binding Proteins; Drug-Related Side Effects and Adverse Reactions; ER | 2003 |
Cardiotoxicity and prescription of thioridazine in New Zealand.
Topics: Antipsychotic Agents; Dose-Response Relationship, Drug; Humans; Long QT Syndrome; New Zealand; Psych | 2002 |
Antipsychotic drugs and QT interval prolongation.
Topics: Age Factors; Algorithms; Antipsychotic Agents; Benzodiazepines; Death, Sudden, Cardiac; Dopamine Ant | 2003 |
[Psychopharmaceuticals and arrhythmias].
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Arrhythmias, Cardiac; Dopamine Antagonists; | 2004 |
3 trials available for thioridazine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
QTc interval lengthening is related to CYP2D6 hydroxylation capacity and plasma concentration of thioridazine in patients.
Topics: Adrenergic Agents; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Biotransformation; Cytochro | 2002 |
A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition.
Topics: Adolescent; Adult; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Benzodiazepines; Biotransfor | 2004 |
Comparison of the effects of thioridazine and mesoridazine on the QT interval in healthy adults after single oral doses.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Area Under Curve; Cross-Over Studies; Dopamine An | 2007 |
14 other studies available for thioridazine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Cation Transport Proteins; Cell Line; Clinical Trials as Topic; Crice | 2002 |
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go- | 2002 |
Prolonged QT Risk Assessment in Antipsychotic Overdose Using the QT Nomogram.
Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Drug Overdose; Electrocardiography; Fema | 2015 |
Antipsychotic medications and cardiac conduction risks.
Topics: Antipsychotic Agents; Comorbidity; Death, Sudden, Cardiac; Electrocardiography; Heart Conduction Sys | 2010 |
[Thioridazine and the warning about prolonged QT time].
Topics: Antipsychotic Agents; Humans; Long QT Syndrome; Psychotic Disorders; Thioridazine | 2002 |
Assessment of QTc prolongation following thioridazine withdrawal in a developmentally disabled population.
Topics: Adult; Child; Developmental Disabilities; Electrocardiography; Female; Humans; Long QT Syndrome; Mal | 2003 |
Re: Thioridazine: re-evaluating the risk/benefit equation.
Topics: Antipsychotic Agents; Data Collection; Death, Sudden; Electrocardiography; Female; Humans; Long QT S | 2003 |
Impact of the CSM advice on thioridazine on general practitioner prescribing behaviour in Leeds: time series analysis.
Topics: Antipsychotic Agents; Drug Approval; England; Family Practice; Humans; Long QT Syndrome; Practice Gu | 2004 |
Practical application of guinea pig telemetry system for QT evaluation.
Topics: Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Bepridil; Cisapride; Disease Models, Animal; | 2005 |
Factors affecting drug concentrations and QT interval during thioridazine therapy.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Antipsychotic Agents; Aryl Hydrocarbon Hydroxy | 2007 |
Psychotropic drugs, HERG, and the heart.
Topics: Antipsychotic Agents; Cation Transport Proteins; DNA-Binding Proteins; ERG1 Potassium Channel; Ether | 2000 |
Thioridazine (Mellaril) and mesoridazine (Serentil): prolongation of the QTc interval.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Contraindications; Heart Conduction System; Humans; Long | 2001 |
The prolongation of QTc-interval by thioridazine.
Topics: Antipsychotic Agents; Humans; Long QT Syndrome; Psychotic Disorders; Thioridazine | 2001 |
Prolongation of QTc interval and antipsychotics.
Topics: Antipsychotic Agents; Death, Sudden, Cardiac; Haloperidol; Humans; Long QT Syndrome; Thioridazine; T | 2002 |