thioridazine has been researched along with Colorectal Cancer in 4 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the effect of thioridazine on the proliferation and apoptosis of human colorectal cancer SW480 cells." | 7.81 | [Mechanism of thioridazine-induced apoptosis of human colorectal cancer SW480 cells]. ( Cai, HB; Hao, YJ; Huang, JW; Li, X; Liu, JK; Peng, K, 2015) |
| " The aim of this study was to evaluate the therapeutic efficiency of immunotherapy with thioridazine and loratadine in combination with resiqumiod (R848), a small-molecule TLR7 agonist, in suppressing CRC growth in a mouse model." | 5.56 | Pre-activation with TLR7 in combination with thioridazine and loratadine promotes tumoricidal T-cell activity in colorectal cancer. ( Chen, T; Lin, G; Lin, X; Wang, X; Zhang, J, 2020) |
| "However, the effect of THIO on colorectal cancer stem cells (CSCs) has not been investigated." | 5.46 | Thioridazine elicits potent antitumor effects in colorectal cancer stem cells. ( Gong, P; Liu, P; Wang, Y; Zhang, C; Zhou, N; Zhou, Y, 2017) |
| "To study the effect of thioridazine on the proliferation and apoptosis of human colorectal cancer SW480 cells." | 3.81 | [Mechanism of thioridazine-induced apoptosis of human colorectal cancer SW480 cells]. ( Cai, HB; Hao, YJ; Huang, JW; Li, X; Liu, JK; Peng, K, 2015) |
| " The aim of this study was to evaluate the therapeutic efficiency of immunotherapy with thioridazine and loratadine in combination with resiqumiod (R848), a small-molecule TLR7 agonist, in suppressing CRC growth in a mouse model." | 1.56 | Pre-activation with TLR7 in combination with thioridazine and loratadine promotes tumoricidal T-cell activity in colorectal cancer. ( Chen, T; Lin, G; Lin, X; Wang, X; Zhang, J, 2020) |
| "However, the effect of THIO on colorectal cancer stem cells (CSCs) has not been investigated." | 1.46 | Thioridazine elicits potent antitumor effects in colorectal cancer stem cells. ( Gong, P; Liu, P; Wang, Y; Zhang, C; Zhou, N; Zhou, Y, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tran, TH | 1 |
| Kao, M | 1 |
| Liu, HS | 1 |
| Hong, YR | 1 |
| Su, Y | 1 |
| Huang, CF | 1 |
| Lin, X | 1 |
| Zhang, J | 1 |
| Wang, X | 1 |
| Lin, G | 1 |
| Chen, T | 1 |
| Liu, JK | 1 |
| Hao, YJ | 1 |
| Huang, JW | 1 |
| Li, X | 1 |
| Cai, HB | 1 |
| Peng, K | 1 |
| Zhang, C | 1 |
| Gong, P | 1 |
| Liu, P | 1 |
| Zhou, N | 1 |
| Zhou, Y | 1 |
| Wang, Y | 1 |
4 other studies available for thioridazine and Colorectal Cancer
| Article | Year |
|---|---|
Repurposing thioridazine for inducing immunogenic cell death in colorectal cancer via eIF2α/ATF4/CHOP and secretory autophagy pathways.
Topics: Animals; Apoptosis; Autophagy; Cell Line, Tumor; Colorectal Neoplasms; Drug Repositioning; Eukaryoti | 2023 |
Pre-activation with TLR7 in combination with thioridazine and loratadine promotes tumoricidal T-cell activity in colorectal cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colorectal Neoplasms; Cyt | 2020 |
[Mechanism of thioridazine-induced apoptosis of human colorectal cancer SW480 cells].
Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferati | 2015 |
Thioridazine elicits potent antitumor effects in colorectal cancer stem cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Gene Expr | 2017 |