thioridazine has been researched along with Chromosomal Translocation in 2 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In pediatric acute myeloid leukemia (AML), intensive chemotherapy and allogeneic hematopoietic stem cell transplantation are the cornerstones of treatment in high-risk cases, with severe late effects and a still high risk of disease recurrence as the main drawbacks." | 1.56 | Thioridazine requires calcium influx to induce MLL-AF6-rearranged AML cell death. ( Benetton, M; Borella, G; Borile, G; Buldini, B; Campello, S; Cogo, P; Da Ros, A; Locatelli, F; Massi, A; Minuzzo, S; Pigazzi, M; Polato, K; Porcù, E; Romagnoli, R; Simonato, M; Simula, L; Tregnago, C, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tregnago, C | 1 |
| Da Ros, A | 1 |
| Porcù, E | 1 |
| Benetton, M | 1 |
| Simonato, M | 1 |
| Simula, L | 1 |
| Borella, G | 1 |
| Polato, K | 1 |
| Minuzzo, S | 1 |
| Borile, G | 1 |
| Cogo, P | 1 |
| Campello, S | 1 |
| Massi, A | 1 |
| Romagnoli, R | 1 |
| Buldini, B | 1 |
| Locatelli, F | 1 |
| Pigazzi, M | 1 |
| Legator, M | 1 |
| Zimmering, S | 1 |
1 review available for thioridazine and Chromosomal Translocation
| Article | Year |
|---|---|
Genetic toxicology.
Topics: Animals; Captan; Chromosomes; Cytogenetics; Drosophila; Drug Evaluation, Preclinical; Genes, Lethal; | 1975 |
1 other study available for thioridazine and Chromosomal Translocation
| Article | Year |
|---|---|
Thioridazine requires calcium influx to induce MLL-AF6-rearranged AML cell death.
Topics: Calcium; Cell Death; Child; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; My | 2020 |