thioridazine and Child Behavior Disorders studies

Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

Child Behavior Disorders: Disturbances considered to be pathological based on age and stage appropriateness, e.g., conduct disturbances and anaclitic depression. This concept does not include psychoneuroses, psychoses, or personality disorders with fixed patterns.

Research Excerpts

Excerpt	Relevance	Reference
"Molindone is a relatively safe neuroleptic for child and adolescent inpatients because of its short half-life and minimal prolonged tissue accumulation."	2.66	Molindone hydrochloride treatment of hospitalized children with conduct disorder. ( Ambrosini, P; Greenhill, LL; Pleak, R; Solomon, M, 1985)
"Thioridazine was dispensed in phases I and III in tablet form and in phases II and IV in suspension, in the same amount of milligrams per subject throughout all four phases."	2.65	Short-term effect of thioridazine tablets versus suspension on emotionally disturbed/retarded children. ( Jakab, I, 1984)
"Those disorders discussed are attention deficit disorder, conduct disorders, anxiety disorders, sleep disorders, schizophrenia, autism, Tourette's syndrome, mental retardation, depressive illness, manic depressive illness, eating disorders, and enuresis."	2.37	Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1). ( McDaniel, KD, 1986)

Timeframe	Studies, this research(%)	All Research%
pre-1990	38 (95.00)	18.7374
1990's	2 (5.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
ALLEN, M	1
SHANNON, G	1
ROSE, D	1
COTLENKO, M	1
PIUCK, CL	1
SHAW, CR	1
LOCKETT, HJ	1
LUCAS, AR	1
LAMONTAGNE, CH	1
GRIMM, F	1
JUDE, JP	1
GATINEAUX, JM	1
MAUPOME, JJ	1
ALDERTON, HR	1
HODDINOTT, BA	1
NOREN, CE	1
Pregelj, S	1
Barkauskas, A	1
Abdou, FA	1
Michaux, L	1
Duche, D	1
Koupernik, C	1
Lelord, G	1
Rolland, M	1
Jakab, I	1
Adams, W	1
Aman, MG	2
Singh, NN	1
Chabot, RJ	1
Orgill, AA	1
Crawford, G	1
Harris, MJ	1
Serfontein, G	1
Heath, A	1
Codd, JA	1
Remschmidt, H	1
Mewe, Fu	1
Dauner, I	1
Merschmann, W	1
Marks, RE	1
Turbott, SH	1
Wilsher, CP	1
Merry, SN	1
McDaniel, KD	1
Greenhill, LL	1
Solomon, M	1
Pleak, R	1
Ambrosini, P	1
Hutt, C	1
Jackson, PM	1
Level, M	1
Krager, JM	1
Safer, DJ	1
Erenberg, G	1
Itil, TM	1
Simeon, J	1
Alexandris, A	1
Lundell, FW	1
Ojeda, PA	1
Baldwin, RW	1
Kenny, TJ	1
Ucer, E	1
Kreger, KC	1
Doyle, JA	1
Maloney, PJ	1
Adams, BR	1
Guillemette, M	1
Marion, G	1
Whillans, J	1
Gordon, AS	1
Simo, J	1
Morrice, P	1
Fletcher, JF	1
Jeffrey, F	1
Vaglum, P	1
Whitehead, PL	1
Clark, LD	1
Grieder, HR	1
Worrell, JB	1
Bell, WE	1
Bos, P	1
Borniche, P	1
Connolly, JR	1
Claveau, JC	1
Tremblay, M	1
Larochelle, J	1
Aubin, G	1
Majdecka, A	1
Vialatte, J	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
The Effects of Methylphenidate (MPH) and Non-invasive Brain Stimulation (tDCS) on Inhibitory Control Children With Attention-Deficit/Hyperactivity Disorder (ADHD)[NCT04964427]		26 participants (Actual)	Interventional	2021-02-08	Completed
Pediatric Attention Deficit Hyperactivity Disorder: Predicting Clinical Response to Stimulant Medication From Single-dose Changes in Event Related Potentials[NCT02695355]	Phase 2	87 participants (Actual)	Interventional	2006-10-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
The usefulness of thioridazine for treating childhood disorders--fact or folklore? American journal of mental deficiency, 1980, Volume: 84, Issue:4 Topics: Child Behavior Disorders; Cognition Disorders; Drug Evaluation; Humans; Intellectual Disability; Lea	1980
Psychiatric drug treatment in children. The Journal of the Maine Medical Association, 1979, Volume: 70, Issue:5 Topics: Adolescent; Amphetamines; Antipsychotic Agents; Anxiety; Autistic Disorder; Behavior Therapy; Child;	1979
Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1). Clinical pediatrics, 1986, Volume: 25, Issue:2 Topics: Adolescent; Aggression; Antidepressive Agents; Antipsychotic Agents; Anxiety, Separation; Attention	1986
Drug therapy in minimal brain dysfunction: a commentary. The Journal of pediatrics, 1972, Volume: 81, Issue:2 Topics: Amphetamine; Anticonvulsants; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity;	1972

Article	Year
Short-term effect of thioridazine tablets versus suspension on emotionally disturbed/retarded children. Journal of clinical psychopharmacology, 1984, Volume: 4, Issue:4 Topics: Adolescent; Child; Child Behavior Disorders; Child, Preschool; Female; Humans; Intellectual Disabili	1984
Behavioral and electrophysiologic predictors of treatment response to stimulants in children with attention disorders. Journal of child neurology, 1999, Volume: 14, Issue:6 Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants;	1999
Behavioral and electrophysiologic predictors of treatment response to stimulants in children with attention disorders. Journal of child neurology, 1999, Volume: 14, Issue:6 Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants;	1999
Behavioral and electrophysiologic predictors of treatment response to stimulants in children with attention disorders. Journal of child neurology, 1999, Volume: 14, Issue:6 Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants;	1999
Behavioral and electrophysiologic predictors of treatment response to stimulants in children with attention disorders. Journal of child neurology, 1999, Volume: 14, Issue:6 Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants;	1999
[The influence of thioridazin (Melleril-Sandoz) on psychomotor functions, concentration power and reactivity in children with behaviour disturbances (author's transl)]. Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1977, Volume: 10, Issue:1 Topics: Adolescent; Child; Child Behavior Disorders; Epilepsy; Female; Humans; Male; Psychomotor Disorders;	1977
Clinical effects of methylphenidate and thioridazine in intellectually subaverage children. Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:2 Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorder	1991
Molindone hydrochloride treatment of hospitalized children with conduct disorder. The Journal of clinical psychiatry, 1985, Volume: 46, Issue:8 Pt 2 Topics: Adolescent; Age Factors; Aggression; Child; Child Behavior Disorders; Clinical Trials as Topic; Doub	1985
Proceedings: Computerized EEG in the prediction of outcome of drug treatment in hyperactive childhood behavior disorders. Psychopharmacology bulletin, 1974, Volume: 10, Issue:4 Topics: Child; Child Behavior Disorders; Clinical Trials as Topic; Computers; Dextroamphetamine; Electroence	1974
Effect of thioridazine, amphetamine and placebo on the hyperkinetic syndrome and cognitive area in mentally deficient children. Canadian Medical Association journal, 1968, Jan-13, Volume: 98, Issue:2 Topics: Aggression; Amphetamine; Attention; Child; Child Behavior Disorders; Clinical Trials as Topic; Human	1968
Treatment with thioridazine of emotionally disturbed children in a day hospital. Michigan medicine, 1970, Volume: 69, Issue:5 Topics: Child; Child Behavior Disorders; Clinical Trials as Topic; Day Care, Medical; Female; Humans; Male;	1970
A double-blind study comparing haloperidol with thioridazine in emotionally disturbed, mentally retarded children. Current therapeutic research, clinical and experimental, 1969, Volume: 11, Issue:5 Topics: Child; Child Behavior Disorders; Clinical Trials as Topic; Female; Haloperidol; Humans; Intellectual	1969
Thioridazine suspension in paediatric practice--a cooperative study. Current therapeutic research, clinical and experimental, 1969, Volume: 11, Issue:7 Topics: Affective Symptoms; Age Factors; Child; Child Behavior Disorders; Child, Preschool; Clinical Trials	1969
Effect of lithium carbonate, placebo, and thioridazine on hyperactive children. The American journal of psychiatry, 1970, Volume: 127, Issue:6 Topics: Carbonates; Child; Child Behavior Disorders; Child, Preschool; Female; Humans; Hyperkinesis; Lithium	1970

thioridazine and Child Behavior Disorders

Research Excerpts

Research

Studies (40)

Authors

Clinical Trials (2)

Trial Overview

Reviews

Trials

Other Studies

Article	Year
Thioridazine hydrochloride in the behavior disturbance of retarded children. American journal of mental deficiency, 1963, Volume: 68 Topics: Attention Deficit and Disruptive Behavior Disorders; Child; Child Behavior Disorders; Humans; Intell	1963
[Treatment of behavior disorders and anxiety states in children with thioridazine drops]. Cahiers R. M. F.: bulletin medical-guide du praticien-revue medicale francaise, 1963, Volume: 77 Topics: Anxiety; Anxiety Disorders; Child; Child Behavior Disorders; Conduct Disorder; Humans; Mental Disord	1963
CLINICAL IMPRESSIONS OF HYDROXYZINE AND OTHER TRANQUILIZERS IN A CHILD GUIDANCE CLINIC. Diseases of the nervous system, 1963, Volume: 24 Topics: Adolescent; Child; Child Behavior Disorders; Child Guidance Clinics; Chlordiazepoxide; Chlorpromazin	1963
TRANQUILIZER DRUGS IN THE TREATMENT OF EMOTIONALLY DISTURBED CHILDREN. I. INPATIENTS IN A RESIDENTIAL TREATMENT CENTER. Journal of the American Academy of Child Psychiatry, 1963, Volume: 2 Topics: Antidepressive Agents; Antisocial Personality Disorder; Benactyzine; Brain; Brain Damage, Chronic; C	1963
[DOMINAL IN CHILD CHARACTER DISORDERS]. Annales medico-psychologiques, 1963, Volume: 121 Topics: Barbiturates; Child; Child Behavior Disorders; Chlorpromazine; Chlorprothixene; Humans; Personality	1963
A CONTROLLED STUDY OF THE USE OF THIORIDAZINE IN THE TREATMENT OF HYPERACTIVE AND AGGRESSIVE CHILDREN IN A CHILDREN'S PSYCHIATRIC HOSPITAL. Canadian Psychiatric Association journal, 1964, Volume: 9 Topics: Aggression; Biomedical Research; Child; Child Behavior Disorders; Hospitals, Pediatric; Hospitals, P	1964
[MALLOROL, A DRUG FOR TREATMENT IN CHILD PSYCHIATRY]. Svenska lakartidningen, 1964, Aug-19, Volume: 61 Topics: Adaptation, Psychological; Biomedical Research; Child; Child Behavior Disorders; Child Psychiatry; C	1964
Thioridazine in the treatment of mentally retarded children. (A four-year retroactive evaluation). Canadian Psychiatric Association journal, 1967, Volume: 12, Issue:2 Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child Behavior Disorders; Child, Preschool; Evaluat	1967
Psychotropic drug therapy in children and adolescents. Virginia medical monthly, 1967, Volume: 94, Issue:8 Topics: Adolescent; Antidepressive Agents; Child; Child Behavior Disorders; Chlorpromazine; Dextroamphetamin	1967
[Results contributed by electroencephalographic conditioning to sound and light to the study of the mechanism of action of psychotrophic drugs]. Annales medico-psychologiques, 1967, Volume: 125, Issue:3 Topics: Adolescent; Adult; Child; Child Behavior Disorders; Chlordiazepoxide; Chlorpromazine; Conditioning,	1967
Treatment of assaultive hair pulling in a multihandicapped youth. Journal of autism and developmental disorders, 1980, Volume: 10, Issue:3 Topics: Aggression; Ammonia; Aversive Therapy; Behavior Therapy; Blindness; Child; Child Behavior Disorders;	1980
Hyperactive children: problems, issues and approaches. The New Zealand medical journal, 1978, Oct-25, Volume: 88, Issue:622 Topics: Amphetamines; Behavior Therapy; Child; Child Behavior Disorders; Counseling; Dextroamphetamine; Fami	1978
Behavioral parameters and drug effects. A study of a hyperkinetic epileptic child. Epilepsia, 1966, Volume: 7, Issue:3 Topics: Anticonvulsants; Child; Child Behavior Disorders; Child, Preschool; Epilepsy; Female; Humans; Infant	1966
Type and prevalence of medication used in the treatment of hyperactive children. The New England journal of medicine, 1974, Nov-21, Volume: 291, Issue:21 Topics: Child; Child Behavior Disorders; Chlorpromazine; Dextroamphetamine; Diphenhydramine; Education, Spec	1974
Thioridazine in the management of organic behavior disturbances in children. Current therapeutic research, clinical and experimental, 1966, Volume: 8, Issue:8 Topics: Adolescent; Brain Damage, Chronic; Child; Child Behavior Disorders; Child, Preschool; Epilepsy; Huma	1966
Thioridazine suspension in pediatric practice: a co-operative study. Applied therapeutics, 1969, Volume: 11, Issue:12 Topics: Child; Child Behavior Disorders; Child, Preschool; Female; Humans; Male; Suspensions; Thioridazine	1969
[Therapeutic utilization of the ego-control-weakening effect of benzodiazepines. New viewpoint on the mechanism of action and indications for use]. Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1969, Volume: 23, Issue:2 Topics: Child; Child Behavior Disorders; Chlordiazepoxide; Diazepam; Ego; Humans; Male; Milieu Therapy; Psyc	1969
[Melleril in pediatrics]. Therapeutische Umschau. Revue therapeutique, 1970, Volume: 27, Issue:2 Topics: Child; Child Behavior Disorders; Child, Preschool; Delayed-Action Preparations; Humans; Sleep Wake D	1970
Management of hyperactive behavior in children. Northwest medicine, 1971, Volume: 70, Issue:1 Topics: Child; Child Behavior Disorders; Child, Preschool; Dextroamphetamine; Humans; Methylphenidate; Thior	1971
[Sudden accident following the administration of Helmirazin in a patient treated with ataraxics]. Ceskoslovenska pediatrie, 1967, Volume: 22, Issue:9 Topics: Adolescent; Anthelmintics; Child Behavior Disorders; Coma; Humans; Male; Thioridazine	1967
[2 percent melleril suspension in pediatric practice]. Semaine therapeutique, 1967, Volume: 43, Issue:2 Topics: Adolescent; Child; Child Behavior Disorders; Child, Preschool; Humans; Infant; Thioridazine	1967
Behavior disorders in mental retardates. Treatment with thioridazine has proved to be an important part of the management of these patients. Pennsylvania medicine, 1968, Volume: 71, Issue:6 Topics: Adolescent; Adult; Behavior; Child; Child Behavior Disorders; Child, Preschool; Emotions; Epilepsy;	1968
[Thioridazine in nervous children]. L'union medicale du Canada, 1968, Volume: 97, Issue:6 Topics: Anorexia Nervosa; Child; Child Behavior Disorders; Child, Preschool; Female; Humans; Infant; Male; T	1968
[The effects of Melleril in the outpatient treatment of children]. Series paedopsychiatrica, 1965, Issue:1 Topics: Adolescent; Child; Child Behavior Disorders; Child, Preschool; Humans; Mental Disorders; Thioridazin	1965
[Behavior disorders in children. Value of symptomatic treatment by a psycholeptic]. Annales de pediatrie, 1966, Nov-02, Volume: 13, Issue:11 Topics: Child; Child Behavior Disorders; Child, Preschool; Female; Humans; Male; Thioridazine	1966