thioridazine has been researched along with Chagas Cardiomyopathy in 3 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
Chagas Cardiomyopathy: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thioridazine (THI) is a tricyclic drug that belongs to the phenothiazine series." | 1.30 | Structural, ultrastructural studies and evolution of Trypanosoma cruzi-infected mice treated with thioridazine. ( Fernández, AR; Fretes, R; Paglini-Oliva, P; Peslman, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lo Presti, MS | 1 |
| Rivarola, HW | 2 |
| Bustamante, JM | 2 |
| Fernández, AR | 3 |
| Enders, JE | 2 |
| Fretes, R | 2 |
| Gea, S | 1 |
| Paglini-Oliva, PA | 1 |
| Presti, MS | 1 |
| Fretes, RE | 1 |
| Paglini-Oliva, P | 2 |
| Peslman, A | 1 |
3 other studies available for thioridazine and Chagas Cardiomyopathy
| Article | Year |
|---|---|
Thioridazine treatment prevents cardiopathy in Trypanosoma cruzi infected mice.
Topics: Animals; Antibodies, Protozoan; Chagas Cardiomyopathy; Chagas Disease; Disease Models, Animal; Elect | 2004 |
Treatment with benznidazole or thioridazine in the chronic phase of experimental Chagas disease improves cardiopathy.
Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Models, Animal; Drug Evalua | 2007 |
Structural, ultrastructural studies and evolution of Trypanosoma cruzi-infected mice treated with thioridazine.
Topics: Animals; Antipsychotic Agents; Chagas Cardiomyopathy; Dose-Response Relationship, Drug; Heart; Male; | 1998 |