Page last updated: 2024-11-05

thioridazine and Basal Ganglia Diseases

thioridazine has been researched along with Basal Ganglia Diseases in 23 studies

Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"This study compared the therapeutic efficacy of thioridazine, loxapine, and a placebo in the treatment of behavioral disturbances in nursing home patients with dementia."3.66Efficacy of antipsychotic medications in behaviorally disturbed dementia patients. ( Barnes, R; Gumbrecht, G; Okimoto, J; Raskind, M; Veith, R, 1982)
"Pimozide was also shown to be effective in a single oral dose not exceeding 16 mg."2.64Pimozide in chronic schizophrenic outpatients. ( Clark, ML; Costiloe, JP; Hill, D; Huber, WK; Wood, F, 1975)
" It is suggested that additional studies, carefully designed, on dosage and plasma levels could help in achieving the lowest possible therapeutic dosage and thus in minimizing side effects."2.37Blood levels of neuroleptics: state of the art. ( Simpson, GM; Yadalam, K, 1985)
"The effect of various antipsychotic drugs on the blockade of dopaminergic receptors in striatum and limbic forebrain was examined by establishing dose-response curves for the increase in HVA and for the antagonism of d-amphetamine-induced rotation in rats with unilateral lesions of the substantia nigra."1.25On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain. ( Dingell, JV; Hill, H; Robinson, SE; Setler, P; Stawarz, RJ; Sulser, F, 1975)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199020 (86.96)18.7374
1990's2 (8.70)18.2507
2000's1 (4.35)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Costentin, J1
Miglets, AW1
Racey, G1
Hoffer, JL1
Barnes, R1
Veith, R1
Okimoto, J1
Raskind, M1
Gumbrecht, G1
Inoue, F1
Janikowski, AM1
Caligiuri, MP1
Rockwell, E1
Jeste, DV1
Trevitt, J1
Atherton, A1
Aberman, J1
Salamone, JD1
Gabriel, E1
Karobath, M1
Lenz, G1
Obukhov, GA1
Stawarz, RJ1
Hill, H1
Robinson, SE1
Setler, P1
Dingell, JV1
Sulser, F1
Clark, ML1
Huber, WK1
Hill, D1
Wood, F1
Costiloe, JP1
Swett, C1
Chouinard, G1
Fontaine, R1
Simpson, GM1
Yadalam, K1
Ananth, J1
Edelmuth, E1
Dargan, B1
Aizenberg, D1
Shalev, A1
Munitz, H1
Steele, C1
Lucas, MJ1
Tune, L1
Beckers, W1
Carlsson, A1
Snyder, SH1
Greenberg, D1
Yamumura, HI1
Jus, A1
Pineau, R1
Jus, K1
Villeneuve, A1
Gautier, J1
Pires, P1
Drolet, A1
Cote, M1
Villeneuve, R1
Bullock, RJ1
McClelland, HA1
Blessed, G1
Bhate, S1
Ali, N1
Clarke, PA1
Diebold, K1

Reviews

1 review available for thioridazine and Basal Ganglia Diseases

ArticleYear
Blood levels of neuroleptics: state of the art.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:5 Pt 2

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Dose-Response Relationship, Drug; Drug

1985

Trials

4 trials available for thioridazine and Basal Ganglia Diseases

ArticleYear
Pimozide in chronic schizophrenic outpatients.
    Diseases of the nervous system, 1975, Volume: 36, Issue:3

    Topics: Adult; Ambulatory Care; Basal Ganglia Diseases; Chronic Disease; Consciousness Disorders; Drug Evalu

1975
Haloperidol versus thioridazine in the treatment of behavioral symptoms in senile dementia of the Alzheimer's type: preliminary findings.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:6

    Topics: Aged; Alzheimer Disease; Basal Ganglia Diseases; Drug Evaluation; Fatigue; Female; Haloperidol; Huma

1986
Penfluridol: a long-acting oral neuroleptic as therapeutic agent in chronic schizophrenia.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:10

    Topics: Adult; Analysis of Variance; Basal Ganglia Diseases; Body Weight; Chlorpromazine; Chronic Disease; C

1974
The abrupt withdrawal of antiparkinsonian drugs in schizophrenic patients.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 124, Issue:579

    Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Behavior; Chlorpromazine; Clinical Trials

1974

Other Studies

18 other studies available for thioridazine and Basal Ganglia Diseases

ArticleYear
[Seeing a new classification of active medications in psychoses].
    L'Encephale, 2007, Volume: 33, Issue:5

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Dopamine D2 Receptor Antagonists; Huma

2007
Phenothiazine induced lingual trauma.
    The Laryngoscope, 1983, Volume: 93, Issue:1

    Topics: Adult; Basal Ganglia Diseases; Diphenhydramine; Edema; Female; Humans; Thioridazine; Tongue

1983
Efficacy of antipsychotic medications in behaviorally disturbed dementia patients.
    The American journal of psychiatry, 1982, Volume: 139, Issue:9

    Topics: Aged; Basal Ganglia Diseases; Dementia; Dibenzoxazepines; Double-Blind Method; Female; Humans; Hypot

1982
Withdrawal akinesia.
    Journal of neurology, neurosurgery, and psychiatry, 1981, Volume: 44, Issue:10

    Topics: Basal Ganglia Diseases; Chlorpromazine; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; Th

1981
Extrapyramidal side effects in patients with Alzheimer's disease treated with low-dose neuroleptic medication.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1998,Winter, Volume: 6, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Antipsychotic Agents; Basal Gangli

1998
Effects of subchronic administration of clozapine, thioridazine and haloperidol on tests related to extrapyramidal motor function in the rat.
    Psychopharmacology, 1998, Volume: 137, Issue:1

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Conditioning, Operant; Haloperidol

1998
[The extrapyramidal symptoms in the combination of lithium long-term lithium therapy with nortriptyline. A case report on the formation of a pathogenesis hypothesis].
    Der Nervenarzt, 1976, Volume: 47, Issue:1

    Topics: Adult; Basal Ganglia Diseases; Bipolar Disorder; Chlorprothixene; Clopenthixol; Dibenzazepines; Drug

1976
[Prolonged action neuroleptics (review of the foreign literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:2

    Topics: Acute Disease; Antipsychotic Agents; Basal Ganglia Diseases; Bipolar Disorder; Child; Chronic Diseas

1975
On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain.
    Psychopharmacologia, 1975, Aug-21, Volume: 43, Issue:2

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Clozapine; Corpus Striatum; D

1975
Drug-induced dystonia.
    The American journal of psychiatry, 1975, Volume: 132, Issue:5

    Topics: Adjustment Disorders; Adult; Basal Ganglia Diseases; Chlorpromazine; Chlorprothixene; Female; Fluphe

1975
Letter: Fluphenazine with other antipsychotic drugs.
    The American journal of psychiatry, 1975, Volume: 132, Issue:7

    Topics: Basal Ganglia Diseases; Chlorpromazine; Drug Administration Schedule; Drug Therapy, Combination; Flu

1975
Meige's syndrome associated with neuroleptic treatment.
    The American journal of psychiatry, 1988, Volume: 145, Issue:4

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Female; Haloperidol; Humans; Male; Meige Syndro

1988
The aftercare of the patient with the neuroleptic malignant syndrome.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 146

    Topics: Adult; Aftercare; Basal Ganglia Diseases; Electroconvulsive Therapy; Humans; Male; Methotrimeprazine

1985
[Gilles de la Tourette's disease based on five own observations].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1973, May-30, Volume: 217, Issue:2

    Topics: Adolescent; Adult; Basal Ganglia Diseases; Compulsive Behavior; Diazepam; Dibenzocycloheptenes; Echo

1973
Antipsychotic drugs and catecholamine synapses.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Binding, Competitive; Brain; Catecholamines; Chlorprom

1974
Antischizophrenic drugs: affinity for muscarinic cholinergic receptor sites in the brain predicts extrapyramidal effects.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Binding, Competitive; Brain; Chlorpromazine;

1974
Efficacy of thiopropazate dihydrochloride (Dartalan) in treating persisting phenothiazine-induced choreo-athetosis and akathisia.
    The Medical journal of Australia, 1972, Aug-05, Volume: 2, Issue:6

    Topics: Aged; Antipsychotic Agents; Athetosis; Basal Ganglia Diseases; Chlorpromazine; Chorea; Female; Human

1972
[Polythymolepsy (combined use of thymoleptics) in cases of endogenous depression].
    International pharmacopsychiatry, 1971, Volume: 6, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Basal Ganglia Diseases; Depression; Dibenzazepines; Drug Thera

1971