thioridazine has been researched along with B16 Melanoma in 2 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated here the effect of four different calmodulin antagonists: thioridazine (10-[2-(1-methyl-2-piperidyl) ethyl]-2-methylthiophenothiazine), CGS 9343B (1,3-dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a] [4,1]-benzoxazepin-4-yl)methyl]-4-piperidinyl]-2 H-benzimidazol-2-one (1:1) maleate), clotrimazole (1-(alpha-2-chlorotrityl)imidazole) and bifonazole (1-(alpha-biphenyl-4-ylbenzyl)imidazole), on the levels of glucose 1,6-bisphosphate and fructose 1,6-bisphosphate, the two stimulatory signal molecules of glycolysis, and on ATP content and cell viability in B16 melanoma cells." | 3.69 | Calmodulin antagonists decrease glucose 1,6-bisphosphate, fructose 1,6-bisphosphate, ATP and viability of melanoma cells. ( Beitner, R; Glass-Marmor, L; Morgenstern, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, X | 1 |
| Chen, Z | 1 |
| Shen, G | 1 |
| Jiang, Y | 1 |
| Wu, L | 1 |
| Li, X | 1 |
| Wang, G | 1 |
| Yin, T | 1 |
| Glass-Marmor, L | 1 |
| Morgenstern, H | 1 |
| Beitner, R | 1 |
2 other studies available for thioridazine and B16 Melanoma
| Article | Year |
|---|---|
Psychotropic agent thioridazine elicits potent in vitro and in vivo anti-melanoma effects.
Topics: Animals; Antineoplastic Agents; Antipsychotic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell P | 2018 |
Calmodulin antagonists decrease glucose 1,6-bisphosphate, fructose 1,6-bisphosphate, ATP and viability of melanoma cells.
Topics: Adenosine Triphosphate; Animals; Benzimidazoles; Calmodulin; Cell Survival; Clotrimazole; Fructosedi | 1996 |