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thioridazine and Astrocytoma, Grade IV

thioridazine has been researched along with Astrocytoma, Grade IV in 2 studies

Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

Research Excerpts

ExcerptRelevanceReference
"Glioblastoma multiforme (GBM) has a poor prognosis with an overall survival of 14-15 months after surgery, radiation and chemotherapy using temozolomide (TMZ)."7.91Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide. ( Bjerkvig, R; Denisova, O; Grudic, A; Hasan-Olive, MM; Janji, B; Johannessen, TC; Latif, MA; Lund-Johansen, M; Nordal, A; Prestegarden, L; Røsland, GV; Saed, H; Simonsen, A; Sundstrøm, T; Tronstad, KJ; Varughese, JK; Wang, J; Westermarck, J; Yang, N; Zhu, H, 2019)
"Glioblastoma multiforme (GBM) has a poor prognosis with an overall survival of 14-15 months after surgery, radiation and chemotherapy using temozolomide (TMZ)."3.91Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide. ( Bjerkvig, R; Denisova, O; Grudic, A; Hasan-Olive, MM; Janji, B; Johannessen, TC; Latif, MA; Lund-Johansen, M; Nordal, A; Prestegarden, L; Røsland, GV; Saed, H; Simonsen, A; Sundstrøm, T; Tronstad, KJ; Varughese, JK; Wang, J; Westermarck, J; Yang, N; Zhu, H, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johannessen, TC1
Hasan-Olive, MM1
Zhu, H1
Denisova, O1
Grudic, A1
Latif, MA1
Saed, H1
Varughese, JK1
Røsland, GV1
Yang, N1
Sundstrøm, T1
Nordal, A1
Tronstad, KJ1
Wang, J1
Lund-Johansen, M1
Simonsen, A1
Janji, B1
Westermarck, J1
Bjerkvig, R1
Prestegarden, L1
Cheng, HW1
Liang, YH1
Kuo, YL1
Chuu, CP1
Lin, CY1
Lee, MH1
Wu, AT1
Yeh, CT1
Chen, EI1
Whang-Peng, J1
Su, CL1
Huang, CY1

Other Studies

2 other studies available for thioridazine and Astrocytoma, Grade IV

ArticleYear
Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide.
    International journal of cancer, 2019, 04-01, Volume: 144, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagosomes; Autophagy; Brain Neoplasms;

2019
Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data.
    Cell death & disease, 2015, May-07, Volume: 6

    Topics: Animals; Antipsychotic Agents; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Drug Scr

2015