thioridazine has been researched along with Arrhythmias, Cardiac in 41 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thioridazine is an antipsychotic that can still be used for schizophrenia although it is associated with the cardiac arrhythmia, torsades de pointe." | 8.84 | Thioridazine for schizophrenia. ( Fenton, M; Rathbone, J; Reilly, J; Sultana, A, 2007) |
| "All cases of arrhythmias associated with thioridazine were reviewed (177 cases)." | 7.68 | Transient cardiac pacing is insufficiently used to treat arrhythmia associated with thioridazine. ( Donatini, B; Krupp, P; Le Blaye, I, 1992) |
| " Physostigmine only caused temporary improvement and the arrhythmias only resolved completely after additional administration of NaCl." | 7.66 | [Arrhythmias in poisoning with tricyclic antidepressive agents. Successful treatment with physostigmine and sodium]. ( Pallmert, N; Seitz, R; Wehr, M, 1982) |
| "No protection against drug-induced arrhythmia or death was afforded by this procedure." | 5.27 | Does chlorpromazine produce cardiac arrhythmia via the central nervous system? ( Lathers, CM; Lipka, LJ; Roberts, J, 1988) |
| "Thioridazine is an antipsychotic that can still be used for schizophrenia although it is associated with the cardiac arrhythmia, torsades de pointe." | 4.84 | Thioridazine for schizophrenia. ( Fenton, M; Rathbone, J; Reilly, J; Sultana, A, 2007) |
| "To compare the rate of ventricular arrhythmia, sudden death and unexplained or unattended death among users of thioridazine and haloperidol." | 3.72 | Comparative cardiac safety of low-dose thioridazine and low-dose haloperidol. ( Bilker, WB; Glasser, DB; Hennessy, S; Kimmel, SE; Knauss, JS; Margolis, DJ; Morrison, MF; Reynolds, RF; Strom, BL, 2004) |
| "Patients with schizophrenia treated with clozapine, haloperidol, risperidone, or thioridazine; a control group of patients with glaucoma; and a control group of patients with psoriasis." | 3.71 | Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative data. ( Bilker, WB; Glasser, DB; Hennessy, S; Kimmel, SE; Knauss, JS; Margolis, DJ; Morrison, MF; Reynolds, RF; Strom, BL, 2002) |
| "All cases of arrhythmias associated with thioridazine were reviewed (177 cases)." | 3.68 | Transient cardiac pacing is insufficiently used to treat arrhythmia associated with thioridazine. ( Donatini, B; Krupp, P; Le Blaye, I, 1992) |
| " Physostigmine only caused temporary improvement and the arrhythmias only resolved completely after additional administration of NaCl." | 3.66 | [Arrhythmias in poisoning with tricyclic antidepressive agents. Successful treatment with physostigmine and sodium]. ( Pallmert, N; Seitz, R; Wehr, M, 1982) |
| " In 4 of the 11 patients, when thioridazine, diuretic drugs and antiarrhythmic agents were withdrawn and hypokalemia or hypocalcemia corrected, ventricular tachyarrhythmias did not recur." | 3.66 | Management of recurrent ventricular tachyarrhythmias associated with Q-T prolongation. ( Adgey, AA; Khan, MM; Logan, KR; McComb, JM, 1981) |
| "Treatment with thioridazine has been associated with electrocardiographic abnormalities, and there are individual case reports of fatal cardiac arrhythmias in patients taking thioridazine." | 3.66 | Electrocardiographic changes following intravenous administration of thioridazine to macaque monkeys. ( Moore, RH; Rainey, JM, 1982) |
| " The ventricular arrhythmias responded to intravenous administration of lidocaine and to direct current electric shock; ventricular pacing was required in some instances and intravenous administration of propranolol combined with ventricular pacing in one." | 3.65 | Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs. ( Chou, TC; Fowler, NO; Hanenson, IB; Holmes, JC; McCall, D, 1976) |
| "Torsades de pointes was originally seen in patients with pre-existing heart disease or with intoxication." | 2.42 | [Psychopharmaceuticals and arrhythmias]. ( Binggeli, C; Brunckhorst, C; Candinas, R, 2004) |
| "Arrhythmia was the most frequently reported serious toxic effect." | 1.29 | Acute overdosage with thioridazine: a review of the available clinical exposure. ( Donatini, B; Hall, M; Krupp, P; Le Blaye, I, 1993) |
| "Mild thioridazine poisoning was characterized by somnolence, tremor, ataxia and dysarthria." | 1.29 | [Acute poisoning with thioridazine]. ( Meier, PJ; Schürch, F; Wyss, PA, 1996) |
| "No protection against drug-induced arrhythmia or death was afforded by this procedure." | 1.27 | Does chlorpromazine produce cardiac arrhythmia via the central nervous system? ( Lathers, CM; Lipka, LJ; Roberts, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (68.29) | 18.7374 |
| 1990's | 4 (9.76) | 18.2507 |
| 2000's | 9 (21.95) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, L | 1 |
| Sun, H | 1 |
| Hennessy, S | 2 |
| Bilker, WB | 2 |
| Knauss, JS | 2 |
| Margolis, DJ | 2 |
| Kimmel, SE | 2 |
| Reynolds, RF | 2 |
| Glasser, DB | 2 |
| Morrison, MF | 2 |
| Strom, BL | 2 |
| KELLY, HG | 1 |
| FAY, JE | 1 |
| LAVERTY, SG | 1 |
| Binggeli, C | 1 |
| Candinas, R | 1 |
| Brunckhorst, C | 1 |
| Bateman, DN | 1 |
| Fenton, M | 1 |
| Rathbone, J | 1 |
| Reilly, J | 1 |
| Sultana, A | 1 |
| Lingjaerde, O | 1 |
| Seitz, R | 1 |
| Wehr, M | 1 |
| Pallmert, N | 1 |
| Khan, MM | 1 |
| Logan, KR | 1 |
| McComb, JM | 1 |
| Adgey, AA | 1 |
| Gould, RJ | 1 |
| Murphy, KM | 1 |
| Reynolds, IJ | 1 |
| Snyder, SH | 1 |
| Moore, RH | 1 |
| Rainey, JM | 1 |
| Forycki, Z | 1 |
| Swica, P | 1 |
| Lipscomb, PA | 1 |
| Le Blaye, I | 2 |
| Donatini, B | 2 |
| Hall, M | 1 |
| Krupp, P | 2 |
| Schürch, F | 1 |
| Meier, PJ | 1 |
| Wyss, PA | 1 |
| Annane, D | 1 |
| Girard, F | 1 |
| Fabre, JE | 1 |
| Raphael, JC | 1 |
| Gajdos, P | 1 |
| Timell, AM | 1 |
| Dallaire, S | 1 |
| Fowler, NO | 1 |
| McCall, D | 1 |
| Chou, TC | 1 |
| Holmes, JC | 1 |
| Hanenson, IB | 1 |
| Levine, DF | 1 |
| Marshall, AJ | 1 |
| Yoon, MS | 1 |
| Han, J | 1 |
| Dersham, GH | 1 |
| Jones, SA | 1 |
| Thornton, WE | 2 |
| Gelenberg, AJ | 1 |
| Urbano Márquez, A | 1 |
| Rubio, M | 1 |
| Fernández-Huerta, JM | 1 |
| Aranalde, JM | 1 |
| Navarro López, F | 1 |
| Pray, BJ | 1 |
| Lipka, LJ | 1 |
| Lathers, CM | 1 |
| Roberts, J | 1 |
| Vertrees, JE | 1 |
| Siebel, G | 1 |
| Flugelman, MY | 1 |
| Tal, A | 1 |
| Pollack, S | 1 |
| Hefez, A | 1 |
| Weisstub, EB | 1 |
| Gotsman, MS | 1 |
| Lewis, BS | 1 |
| Hollow, VM | 1 |
| Clarke, GM | 1 |
| Weekes, JW | 1 |
| Newton, RW | 1 |
| Shamsi, MA | 1 |
| Kulshrestha, VK | 1 |
| Dhawan, KN | 1 |
| Bhargava, KP | 1 |
| Landmark, K | 1 |
| Hollander, PB | 1 |
| Cain, RM | 1 |
| Kalbian, VV | 1 |
| Burda, CD | 1 |
| Tranum, BL | 1 |
| Murphy, ML | 1 |
| Fletcher, GF | 1 |
| Kazamias, TM | 1 |
| Schoonmaker, FW | 1 |
| Osteen, RT | 1 |
| Greenfield, JC | 1 |
2 reviews available for thioridazine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
[Psychopharmaceuticals and arrhythmias].
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Arrhythmias, Cardiac; Dopamine Antagonists; | 2004 |
Thioridazine for schizophrenia.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Humans; Outcome Assessment, Health Care; Randomized Cont | 2007 |
39 other studies available for thioridazine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant | 2008 |
Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative data.
Topics: Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Clozapine; Cohort Studies; Confidence Inter | 2002 |
THIORIDAZINE HYDROCHLORIDE (MELLARIL): ITS EFFECT ON THE ELECTROCARDIOGRAM AND A REPORT OF TWO FATALITIES WITH ELECTROCARDIOGRAPHIC ABNORMALITIES.
Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Electrocardiography; Hear | 1963 |
Comparative cardiac safety of low-dose thioridazine and low-dose haloperidol.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Child; Child, Preschool; Cohort | 2004 |
Clinical toxicology: clinical science to public health.
Topics: Analgesics, Opioid; Antipsychotic Agents; Arrhythmias, Cardiac; Dextropropoxyphene; Drug Information | 2005 |
[Electrocardiographic changes, disturbances of cardiac rhythm, and sudden deaths during treatment with phenothiazine drugs].
Topics: Arrhythmias, Cardiac; Death, Sudden; Female; Heart Arrest; Humans; Middle Aged; Quinidine; Tachycard | 1967 |
[Arrhythmias in poisoning with tricyclic antidepressive agents. Successful treatment with physostigmine and sodium].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Dibenzazepines; Female; Human | 1982 |
Management of recurrent ventricular tachyarrhythmias associated with Q-T prolongation.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Gluconate; Cardiac Pacing, Artifi | 1981 |
Calcium channel blockade: possible explanation for thioridazine's peripheral side effects.
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Ejaculation; Female; Ion Channels; Male; Mu | 1984 |
Electrocardiographic changes following intravenous administration of thioridazine to macaque monkeys.
Topics: Animals; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Electrocardiography; Heart Conducti | 1982 |
[Recurrent ventricular flutter after thioridazine poisoning].
Topics: Adult; Arrhythmias, Cardiac; Female; Heart Ventricles; Humans; Recurrence; Thioridazine | 1982 |
Cardiovascular side effects of phenothiazines and tricyclic antidepressants. A review with precautionary measures.
Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular System; Death, Sudden; Drug I | 1980 |
Acute overdosage with thioridazine: a review of the available clinical exposure.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Child; Child, Preschool; Drug Over | 1993 |
[Acute poisoning with thioridazine].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Arrhythmias, Cardiac; Case-Control | 1996 |
Near fatal case of self-poisoning with thioridazine.
Topics: Adult; Antipsychotic Agents; Arrhythmias, Cardiac; Coma; Electrocardiography; Female; Humans; Thiori | 1996 |
Thioridazine: re-evaluating the risk/benefit equation.
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Arrhythmias, Cardiac; Cause of Death; Female; | 2000 |
Thioridazine (Mellaril) and mesoridazine (Serentil): prolongation of the QTc interval.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Contraindications; Heart Conduction System; Humans; Long | 2001 |
Thioridazine and severe cardiac arrhythmia.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Contraindications; Drug Interactions; France; Schizophre | 2001 |
Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs.
Topics: Adrenergic Agonists; Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovasc | 1976 |
Letter: Cardiac arrhythmia induced by phenothiazine.
Topics: Adult; Arrhythmias, Cardiac; Humans; Male; Thioridazine | 1975 |
Effects of thioridazine (Mellaril) on ventricular electrophysiologic properties.
Topics: Animals; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Dogs; Dose-Response Relationship, Drug; H | 1979 |
Alcohol withdrawal and thioridazine.
Topics: Alcoholism; Arrhythmias, Cardiac; Humans; Substance Withdrawal Syndrome; Thioridazine | 1977 |
Cardiac arrhythmias after psychotropic drugs.
Topics: Arrhythmias, Cardiac; Humans; Psychotropic Drugs; Thioridazine | 1977 |
[Electrocardiographic disorders induced by thioridazine poisoning. Apropos of 2 cases of acute poisoning].
Topics: Acute Disease; Adult; Arrhythmias, Cardiac; Depression; Electrocardiography; Female; Humans; Middle | 1976 |
Ventricular arrhythmia and thioridazine: a case report.
Topics: Adult; Arrhythmias, Cardiac; Female; Heart Ventricles; Humans; Hypokalemia; Thioridazine | 1976 |
Transient cardiac pacing is insufficiently used to treat arrhythmia associated with thioridazine.
Topics: Adult; Arrhythmias, Cardiac; Bundle-Branch Block; Cardiac Pacing, Artificial; Child; Dose-Response R | 1992 |
Does chlorpromazine produce cardiac arrhythmia via the central nervous system?
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Central Nervous System; Chlorpromazine; Decereb | 1988 |
Rapid death resulting from mesoridazine overdose.
Topics: Adult; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Male; Mesoridazine; Middle Aged; T | 1987 |
Psychotropic drugs and long QT syndromes: case reports.
Topics: Aged; Arrhythmias, Cardiac; Depressive Disorder; Electrocardiography; Female; Humans; Middle Aged; P | 1985 |
Case report: thioridazine overdose.
Topics: Arrhythmias, Cardiac; Atropine; Electrocardiography; Female; Humans; Lidocaine; Middle Aged; Procain | 1974 |
Letter: Ventricular dysrhythmias and thioridazine in alcohol withdrawal.
Topics: Alcoholism; Arrhythmias, Cardiac; Electrocardiography; Humans; Hypokalemia; Substance Withdrawal Syn | 1973 |
Correlation of chemical structure of phenothiazines with their coronary dilator and antiarrhythmic activities.
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chlorpromazine; Coronary Vessels; | 1971 |
The action of promazine and thioridazine in isolated rat atria. 1. Effects on automaticity, mechanical performance, refractoriness and excitability.
Topics: Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Electric Stimulation; Female; Heart Arrest; Hear | 1971 |
Effects of thioridazine on transmembrane potential and contractile characteristics of guinea pig hearts.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Electric Stimulation; Electrophysiology; Guinea Pi | 1971 |
Electrocardiogram of the month. Q-T prolongation associated with the use of thioridazine hydrochloride (Mellaril).
Topics: Arrhythmias, Cardiac; Electrocardiography; Humans; Male; Middle Aged; Schizophrenia; Thioridazine | 1971 |
Electrocardiographic abnormalities induced by thioridazine (Mellaril).
Topics: Arrhythmias, Cardiac; Child; Electrocardiography; Humans; Male; Suicide; Tachycardia; Thioridazine | 1968 |
Case report: successful treatment of ventricular tachycardia associated with thioridazine (Mellaril).
Topics: Arrhythmias, Cardiac; Aspartate Aminotransferases; Electric Countershock; Electrocardiography; Human | 1969 |
Cardiotoxic effects of Mellaril: conduction disturbances and supraventricular arrhythmias.
Topics: Adult; Arrhythmias, Cardiac; Electrocardiography; Female; Heart Conduction System; Humans; Male; Mid | 1969 |
Thioridazine (mellaril)-induced ventricular tachycardia controlled with an artificial pacemaker.
Topics: Arrhythmias, Cardiac; Electrocardiography; Humans; Male; Middle Aged; Pacemaker, Artificial; Thiorid | 1966 |