thioridazine has been researched along with Anochlesia in 21 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Muscle rigidity was assessed quantitatively and objectively as increases in electromyographic (EMG) activity (muscle rigidity) in the hindlimb muscles of the rat following subcutaneous administration of haloperidol, fluphenazine and thioridazine." | 3.71 | An animal model of extrapyramidal side effects induced by antipsychotic drugs: relationship with D2 dopamine receptor occupancy. ( Crocker, AD; Hemsley, KM, 2001) |
| " The compound was essentially inactive in binding to dopamine D2 receptors and its chronic administration to rats did not result in dopamine receptor supersensitivity." | 1.28 | Synthesis and biological characterization of alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanol and analogues as potential atypical antipsychotic agents. ( Bernstein, E; Dextraze, P; Eison, MS; Lobeck, WG; New, JS; Taylor, DP; Temple, DL; Yevich, JP; Yocca, FD, 1992) |
| " The compound's lack of typical neuroleptic-like effects in the rat catalepsy test and its failure to produce dopamine receptor supersensitivity following chronic administration indicate that it should not cause the movement disorders commonly associated with antipsychotic therapy." | 1.27 | Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents. ( Catt, JD; Eison, MS; Lobeck, WG; Minielli, JL; New, JS; Riblet, LA; Smith, DW; Taylor, DP; Temple, DL; Yevich, JP, 1986) |
| "At doses known to elicit catalepsy in rats, haloperidol (1." | 1.27 | Cataleptogenic potency of the antipsychotic drugs is inversely correlated with neuronal activity in the amygdaloid complex of the rat. ( Alloway, KD; Bashore, TR; Gelman, J; Rebec, GV, 1983) |
| "Remoxipride was shown to be a selective dopamine D2 receptor antagonist since it displaced [3H]spiperone (IC50 = 1570 nM) but not [3H]flupentixol (IC50 greater than 100 000 nM) in rat striatum, and did not inhibit striatal DA-sensitive adenylate cyclase in vitro (IC50 greater than 100 000 nM)." | 1.27 | Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain. ( Angeby, K; Florvall, L; Hall, H; Köhler, C; Lindbom, LO; Magnusson, O; Ogren, SO, 1984) |
| "(+)-Thioridazine was shown to have 2." | 1.27 | Receptor affinity, neurochemistry and behavioral characteristics of the enantiomers of thioridazine: evidence for different stereoselectivities at D1 and D2 receptors in rat brain. ( Babb, S; Baldessarini, RJ; Bird, ED; Campbell, A; Cohen, BM; Froimowitz, M; Hrbek, C; Kula, N; Svendsen, CN; Teicher, MH, 1988) |
| "Initial catalepsy and inhibition of spontaneous locomotion disappeared by 3 months and thereafter." | 1.26 | Changes in dopamine-mediated behaviour during one year's neuroleptic administration. ( Clow, A; Jenner, P; Marsden, CD, 1979) |
| " SHPGE2, PGE2, and C did not cause catalepsy and did not show statistically significant dose-response antagonism of rotational behavior at less than toxic doses." | 1.26 | Neuropharmacological and behavioral evaluation of prostaglandin E2 and 11-thiol-11-desoxy prostaglandin E2 in the mouse and rat. ( Bloss, JL; Singer, GH, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (90.48) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Voith, K | 1 |
| Bruderlein, FT | 1 |
| Humber, LG | 1 |
| Yevich, JP | 2 |
| New, JS | 2 |
| Lobeck, WG | 2 |
| Dextraze, P | 1 |
| Bernstein, E | 1 |
| Taylor, DP | 2 |
| Yocca, FD | 1 |
| Eison, MS | 2 |
| Temple, DL | 2 |
| Smith, DW | 1 |
| Catt, JD | 1 |
| Minielli, JL | 1 |
| Riblet, LA | 1 |
| Chakrabarti, JK | 2 |
| Horsman, L | 2 |
| Hotten, TM | 1 |
| Pullar, IA | 2 |
| Tupper, DE | 2 |
| Wright, FC | 2 |
| Fairhurst, J | 1 |
| Gutteridge, NJ | 1 |
| Smith, CW | 1 |
| Steggles, DJ | 1 |
| NAKAJIMA, H | 1 |
| GRANDJEAN, JL | 1 |
| LHUILLIER, J | 1 |
| THUILLIER, J | 1 |
| Barghon, R | 1 |
| Protais, P | 1 |
| Colboc, O | 1 |
| Costentin, J | 1 |
| Rebec, GV | 1 |
| Gelman, J | 1 |
| Alloway, KD | 1 |
| Bashore, TR | 1 |
| Ogren, SO | 1 |
| Hall, H | 1 |
| Köhler, C | 1 |
| Magnusson, O | 1 |
| Lindbom, LO | 1 |
| Angeby, K | 1 |
| Florvall, L | 1 |
| Crocker, AD | 1 |
| Hemsley, KM | 1 |
| Clow, A | 1 |
| Jenner, P | 1 |
| Marsden, CD | 1 |
| Bloss, JL | 1 |
| Singer, GH | 1 |
| Honma, T | 1 |
| Fukushima, H | 1 |
| Wójciakowa, Z | 1 |
| Kozaryn, I | 1 |
| Costall, B | 2 |
| Naylor, RJ | 2 |
| Svendsen, CN | 1 |
| Froimowitz, M | 1 |
| Hrbek, C | 1 |
| Campbell, A | 1 |
| Kula, N | 1 |
| Baldessarini, RJ | 1 |
| Cohen, BM | 1 |
| Babb, S | 1 |
| Teicher, MH | 1 |
| Bird, ED | 1 |
| Muller, P | 1 |
| Seeman, P | 1 |
| Theobald, W | 1 |
| Büch, O | 1 |
| Delini-Stula, A | 1 |
| Eigenmann, R | 1 |
| Levin, P | 1 |
| Loew, DM | 1 |
| Niemegeers, CJ | 1 |
| Verbruggen, FJ | 1 |
| Janssen, PA | 1 |
21 other studies available for thioridazine and Anochlesia
| Article | Year |
|---|---|
Neuroleptics related to butaclamol. Synthesis and some psychopharmacological effects of a series of 3-aryl analogues.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Butaclamol; Catalepsy; Conditioning, Psychologica | 1978 |
Synthesis and biological characterization of alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanol and analogues as potential atypical antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Catalepsy; Molecular Structure; Piperazines; Pyri | 1992 |
Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Binding, Competitive; Catalepsy; Cerebral Cortex; | 1986 |
4-Piperazinyl-10H-thieno[2,3-b][1,5]benzodiazepines as potential neuroleptics.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Body Temperature; Catalepsy; Hum | 1980 |
10-Piperazinyl-4H-theino[3,2-b][1,5]- and -[3,4-b][1,5]benzodiazepines as potential neuroleptics.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Body Temperature; Catalepsy; Hum | 1980 |
[EXPERIMENTAL ANTAGONISM OF CHLORPROMAZINE AND THIORIDAZINE IN RELATION TO CERTAIN EFFECTS OF LYSERGIDE].
Topics: 5-Hydroxytryptophan; Catalepsy; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hypothermia; Lysergi | 1964 |
Hypokinesia in mice and catalepsy in rats elicited by morphine associated with antidopaminergic agents, including atypical neuroleptics.
Topics: alpha-Methyltyrosine; Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Clozapine; Haloperidol; | 1981 |
Cataleptogenic potency of the antipsychotic drugs is inversely correlated with neuronal activity in the amygdaloid complex of the rat.
Topics: Action Potentials; Amygdala; Animals; Antipsychotic Agents; Catalepsy; Chlorpromazine; Clozapine; Do | 1983 |
Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzamides; Binding | 1984 |
An animal model of extrapyramidal side effects induced by antipsychotic drugs: relationship with D2 dopamine receptor occupancy.
Topics: Animals; Antipsychotic Agents; Catalepsy; Corpus Striatum; Disease Models, Animal; Dose-Response Rel | 2001 |
Changes in dopamine-mediated behaviour during one year's neuroleptic administration.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Catalepsy; Dopamine; Dyskinesia, Drug-Induced; Huma | 1979 |
Neuropharmacological and behavioral evaluation of prostaglandin E2 and 11-thiol-11-desoxy prostaglandin E2 in the mouse and rat.
Topics: Animals; Avoidance Learning; Behavior, Animal; Catalepsy; Clozapine; Dextroamphetamine; Fluphenazine | 1978 |
Correlation between catalepsy and dopamine decrease in the rat striatum induced by neuroleptics.
Topics: Animals; Butyrophenones; Catalepsy; Chlorpromazine; Clozapine; Corpus Striatum; Dopamine; Dose-Respo | 1976 |
The influence of cystamine on pharmacokinetics and pharmacodynamics of thioridazine.
Topics: Animals; Bile; Brain; Catalepsy; Cystamine; Glucuronidase; Humans; Kinetics; Male; Movement; Rats; T | 1976 |
Detection of the nueroleptic properties of clozapine, sulpiride and thioridazine.
Topics: Animals; Apomorphine; Behavior, Animal; Catalepsy; Clozapine; Dextroamphetamine; Dibenzazepines; Dos | 1975 |
Receptor affinity, neurochemistry and behavioral characteristics of the enantiomers of thioridazine: evidence for different stereoselectivities at D1 and D2 receptors in rat brain.
Topics: Animals; Benzazepines; Brain Chemistry; Catalepsy; Dopamine Antagonists; Male; Norepinephrine; Prazo | 1988 |
Neuroleptics: relation between cataleptic and anti-turning actions, and role of the cholinergic system.
Topics: Amphetamine; Animals; Behavior; Catalepsy; Chlorpromazine; Humans; Parasympathetic Nervous System; P | 1974 |
[Pharmacological studies on the effect of neuroleptics in animals after single and repeated application].
Topics: Amphetamine; Animals; Apomorphine; Body Temperature; Catalepsy; Cats; Chlorpromazine; Conditioning, | 1968 |
Is there a relationship between the involvement of extrapyramidal and mesolimbic brain areas with the cataleptic action of neuroleptic agents and their clinical antipsychotic effect?
Topics: Animals; Aporphines; Benzoates; Butyrophenones; Catalepsy; Dioxoles; Extrapyramidal Tracts; Humans; | 1973 |
The prediction of sedative potency of neuroleptics.
Topics: Animals; Ataxia; Avoidance Learning; Catalepsy; Chlorpromazine; Haloperidol; Humans; Hypnotics and S | 1970 |
The influence of various neuroleptic drugs on noise escape response in rats.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Benperidol; Blepharoptosis; Butyrophenones; Cata | 1970 |