thioridazine has been researched along with American Trypanosomiasis in 5 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thioridazine (TDZ) is a phenothiazine that has been shown to be one of the most potent phenothiazines to inhibit trypanothione reductase irreversibly." | 6.52 | Trypanothione reductase inhibitors: Overview of the action of thioridazine in different stages of Chagas disease. ( Báez, AL; Bazán, PC; Lo Presti, MS; Paglini-Oliva, PA; Rivarola, HW; Strauss, M, 2015) |
| "Thioridazine (TDZ) is a phenothiazine that has been shown to be one of the most potent phenothiazines to inhibit trypanothione reductase irreversibly." | 2.52 | Trypanothione reductase inhibitors: Overview of the action of thioridazine in different stages of Chagas disease. ( Báez, AL; Bazán, PC; Lo Presti, MS; Paglini-Oliva, PA; Rivarola, HW; Strauss, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mendonça, AAS | 1 |
| Gonçalves-Santos, E | 1 |
| Souza-Silva, TG | 1 |
| González-Lozano, KJ | 1 |
| Caldas, IS | 1 |
| Gonçalves, RV | 1 |
| Diniz, LF | 1 |
| Novaes, RD | 1 |
| Lo Presti, MS | 2 |
| Bazán, PC | 1 |
| Strauss, M | 1 |
| Báez, AL | 1 |
| Rivarola, HW | 4 |
| Paglini-Oliva, PA | 2 |
| Bustamante, JM | 2 |
| Fernández, AR | 3 |
| Enders, JE | 3 |
| Fretes, R | 2 |
| Gea, S | 2 |
| Presti, MS | 1 |
| Fretes, RE | 1 |
| Paglini-Oliva, P | 2 |
| Suligoy, M | 1 |
| Palma, JA | 1 |
1 review available for thioridazine and American Trypanosomiasis
| Article | Year |
|---|---|
Trypanothione reductase inhibitors: Overview of the action of thioridazine in different stages of Chagas disease.
Topics: Animals; Chagas Disease; Dose-Response Relationship, Drug; Enzyme Inhibitors; Mice; NADH, NADPH Oxid | 2015 |
4 other studies available for thioridazine and American Trypanosomiasis
| Article | Year |
|---|---|
Thioridazine aggravates skeletal myositis, systemic and liver inflammation in Trypanosoma cruzi-infected and benznidazole-treated mice.
Topics: Acetylglucosaminidase; Animals; Chagas Disease; Cytokines; Disease Models, Animal; Drug Combinations | 2020 |
Thioridazine treatment prevents cardiopathy in Trypanosoma cruzi infected mice.
Topics: Animals; Antibodies, Protozoan; Chagas Cardiomyopathy; Chagas Disease; Disease Models, Animal; Elect | 2004 |
Treatment with benznidazole or thioridazine in the chronic phase of experimental Chagas disease improves cardiopathy.
Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Models, Animal; Drug Evalua | 2007 |
Thioridazine treatment modifies the evolution of Trypanosoma cruzi infection in mice.
Topics: Animals; Chagas Disease; Drug Evaluation, Preclinical; Mice; Thioridazine; Trypanocidal Agents; Tryp | 1999 |