thioridazine has been researched along with Alzheimer Disease in 14 studies
Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlormethiazole treatment also resulted in significant reductions in physical disability as assessed by the Clifton Behaviour Rating Scale." | 2.66 | A comparison of chlormethiazole and thioridazine in agitated confusional states of the elderly. ( Ather, SA; Shaw, SH; Stoker, MJ, 1986) |
| "Unlike the more common causes of dysphagia, especially in the elderly, drug-induced dysphagia may be reversible." | 1.30 | Neuroleptic-induced dysphagia. ( Pavlakovic, R; Sokoloff, LG, 1997) |
| "Monozygotic twins with Alzheimer's disease of 8 years duration were studied." | 1.30 | Monozygotic twins with Alzheimer's disease treated with melatonin: Case report. ( Brusco, LI; Cardinali, DP; Márquez, M, 1998) |
| "Two agitated patients with Alzheimer's disease who either failed to respond or worsened with conventional low-dose neuroleptic and other pharmacologic treatment are described." | 1.27 | Very low-dose neuroleptic treatment in two patients with agitation associated with Alzheimer's disease. ( Cubberley, L; Lampe, TH; Risse, SC, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tyler, KL | 1 |
| Tyler, HR | 1 |
| Reisberg, B | 3 |
| Ferris, SH | 2 |
| Gershon, S | 1 |
| Devanand, DP | 1 |
| Auer, SR | 1 |
| Monteiro, IM | 1 |
| Sokoloff, LG | 1 |
| Pavlakovic, R | 1 |
| Caligiuri, MP | 1 |
| Rockwell, E | 1 |
| Jeste, DV | 1 |
| Brusco, LI | 1 |
| Márquez, M | 1 |
| Cardinali, DP | 1 |
| Tune, LE | 1 |
| Steele, C | 2 |
| Cooper, T | 1 |
| Risse, SC | 2 |
| Lampe, TH | 2 |
| Cubberley, L | 1 |
| Raskind, MA | 1 |
| Ather, SA | 1 |
| Shaw, SH | 1 |
| Stoker, MJ | 1 |
| Borenstein, J | 1 |
| Salob, SP | 1 |
| Franssen, E | 1 |
| Georgotas, A | 1 |
| Lucas, MJ | 1 |
| Tune, L | 1 |
| Asnes, DP | 1 |
1 review available for thioridazine and Alzheimer Disease
| Article | Year |
|---|---|
Pharmacotherapy of senile dementia.
Topics: Adult; Age Factors; Aged; Alzheimer Disease; Amphetamine; Antidepressive Agents, Tricyclic; Dementia | 1980 |
6 trials available for thioridazine and Alzheimer Disease
| Article | Year |
|---|---|
Behavioral symptoms in dementia: community-based research.
Topics: Aged; Alzheimer Disease; Ambulatory Care; Antipsychotic Agents; Dementia; Double-Blind Method; Femal | 1996 |
Neuroleptic drugs in the management of behavioral symptoms of Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Behavior; Double-Blind Method; Female; Haloperidol; H | 1991 |
Dementia and antipsychotic drugs.
Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Clinical Trials as Topic; Cognition Disorders; Dement | 1987 |
A comparison of chlormethiazole and thioridazine in agitated confusional states of the elderly.
Topics: Aged; Alzheimer Disease; Chlormethiazole; Clinical Trials as Topic; Cognition Disorders; Confusion; | 1986 |
Behavioral symptoms in Alzheimer's disease: phenomenology and treatment.
Topics: Aged; Alzheimer Disease; Circadian Rhythm; Clinical Trials as Topic; Delusions; Female; Humans; Male | 1987 |
Haloperidol versus thioridazine in the treatment of behavioral symptoms in senile dementia of the Alzheimer's type: preliminary findings.
Topics: Aged; Alzheimer Disease; Basal Ganglia Diseases; Drug Evaluation; Fatigue; Female; Haloperidol; Huma | 1986 |
7 other studies available for thioridazine and Alzheimer Disease
| Article | Year |
|---|---|
Differentiating organic dementia.
Topics: Adult; Aged; Aging; Alzheimer Disease; Dementia; Diagnosis, Differential; Female; Humans; Male; Meta | 1984 |
Antipsychotic treatment in outpatients with dementia.
Topics: Aged; Alzheimer Disease; Ambulatory Care; Antipsychotic Agents; Chlorpromazine; Dementia; Dose-Respo | 1996 |
Neuroleptic-induced dysphagia.
Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Deglutition Disorders; Fluoroscopy; Haloperidol; Huma | 1997 |
Extrapyramidal side effects in patients with Alzheimer's disease treated with low-dose neuroleptic medication.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Antipsychotic Agents; Basal Gangli | 1998 |
Monozygotic twins with Alzheimer's disease treated with melatonin: Case report.
Topics: Aged; Alzheimer Disease; Antioxidants; Brain; Diseases in Twins; Humans; Magnetic Resonance Imaging; | 1998 |
Very low-dose neuroleptic treatment in two patients with agitation associated with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Haloperidol; Humans; Male; Middle | 1987 |
Psychopharmacology in the aged. Use of major psychotropic medications in treatment of the elderly: case examples.
Topics: Adjustment Disorders; Aged; Alzheimer Disease; Amitriptyline; Benztropine; Bipolar Disorder; Cataton | 1974 |