Page last updated: 2024-11-05

thioridazine and Aggression

thioridazine has been researched along with Aggression in 29 studies

Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
"As part of a pilot study to assess the efficacy of propranolol in the treatment of aggression in psychiatric patients, drug interactions of propranolol with other agents were estimated by blood level monitoring."3.67Elevation of thioridazine plasma levels by propranolol. ( Katz, BL; Kogan, M; Silver, JM; Yudofsky, SC, 1986)
"Molindone is a relatively safe neuroleptic for child and adolescent inpatients because of its short half-life and minimal prolonged tissue accumulation."2.66Molindone hydrochloride treatment of hospitalized children with conduct disorder. ( Ambrosini, P; Greenhill, LL; Pleak, R; Solomon, M, 1985)
"The results suggest that, in mental retardation, physical restraint of hyperactivity might induce aggressivity and that one should be cautious in using neuroleptics in nonpsychotic patients."2.65Comparison of SCH-12679 and thioridazine in aggressive mental retardates. ( Albert, JM; Cooper, SF; Elie, R; Gravel, G; Langlois, Y, 1980)
"Those disorders discussed are attention deficit disorder, conduct disorders, anxiety disorders, sleep disorders, schizophrenia, autism, Tourette's syndrome, mental retardation, depressive illness, manic depressive illness, eating disorders, and enuresis."2.37Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1). ( McDaniel, KD, 1986)
"Thioridazine was variable across clients, settings, behaviors, and dosages."1.27Clinical behavioral pharmacology: methods for evaluating medications and contingency management. ( Burgio, LD; Capriotti, RM; Page, TJ, 1985)
"Apomorphine was found to induce either a "sniffing/burrowing" or a "fighting" stereotypy."1.26Behavioural effects of chronic treatment with apomorphine in combination with neuroleptic drugs. ( Kenny, M; Leonard, BE, 1980)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199028 (96.55)18.7374
1990's1 (3.45)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SANCHEZ LONGO, LP1
IFARRAGUERRI, A1
STABENAU, JR1
GRINOLS, DR1
ALDERTON, HR1
HODDINOTT, BA1
STILSON, DW1
KOPELL, BS1
HINDLEY, JP1
KERIN, MT1
THOMPSON, M1
Kenny, M1
Leonard, BE1
Breuning, SE2
Ferguson, DG1
Davidson, NA1
Poling, AD1
Adams, W1
Elie, R1
Langlois, Y1
Cooper, SF1
Gravel, G1
Albert, JM1
Kumar, BB1
Wong, SE1
Floyd, J1
Innocent, AJ1
Woolsey, JE1
McDaniel, KD1
von Hafften, AH1
Jensen, CF1
Aman, MG1
Singh, NN1
Smeraski, PJ1
Cohen-Mansfield, J1
Silver, JM1
Yudofsky, SC1
Kogan, M1
Katz, BL1
Greenhill, LL1
Solomon, M1
Pleak, R1
Ambrosini, P1
Burgio, LD1
Page, TJ1
Capriotti, RM1
Donlon, PT1
Blacker, KH1
Montanini, R1
Mastruzzo, A1
Giovannucci, M1
Alexandris, A1
Lundell, FW1
Ferris, GN1
Cwynar, S1
Rydzyński, Z1
Weychert, A1
Simińska, S1
Madej, A1
Grzelak, L1
Wohlfarth-Ribbentrop, A1
Schaumann, W1
Senault, B1
Nievoll, A1
Sofia, RD1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Can Virtual Reality Reduce Depression and Agitation in Older Adults With Moderate to Severe Dementia? A Randomized Controlled Trial.[NCT04347668]266 participants (Anticipated)Interventional2019-04-01Recruiting
Low Dose Ionizing Radiation Using CT Scans as a Potential Therapy for Alzheimer's Dementia (LDIR-CT-AD) Trial: A Pilot Study[NCT03597360]4 participants (Actual)Interventional2019-01-08Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for thioridazine and Aggression

ArticleYear
Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1).
    Clinical pediatrics, 1986, Volume: 25, Issue:2

    Topics: Adolescent; Aggression; Antidepressive Agents; Antipsychotic Agents; Anxiety, Separation; Attention

1986

Trials

4 trials available for thioridazine and Aggression

ArticleYear
Effects of thioridazine on the intellectual performance of mentally retarded drug responders and nonresponders.
    Archives of general psychiatry, 1983, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Aggression; Child; Double-Blind Method; Female; Humans; Intellectual Disability;

1983
Comparison of SCH-12679 and thioridazine in aggressive mental retardates.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1980, Volume: 25, Issue:6

    Topics: Aggression; Benzazepines; Humans; Intellectual Disability; Motor Activity; Psychiatric Status Rating

1980
Molindone hydrochloride treatment of hospitalized children with conduct disorder.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:8 Pt 2

    Topics: Adolescent; Age Factors; Aggression; Child; Child Behavior Disorders; Clinical Trials as Topic; Doub

1985
Effect of thioridazine, amphetamine and placebo on the hyperkinetic syndrome and cognitive area in mentally deficient children.
    Canadian Medical Association journal, 1968, Jan-13, Volume: 98, Issue:2

    Topics: Aggression; Amphetamine; Attention; Child; Child Behavior Disorders; Clinical Trials as Topic; Human

1968

Other Studies

24 other studies available for thioridazine and Aggression

ArticleYear
The control of aggressive behavior in organic brain syndromes with the use of thioridazine.
    Boletin de la Asociacion Medica de Puerto Rico, 1961, Volume: 53

    Topics: Aggression; Brain; Brain Injuries; Psychotic Disorders; Syndrome; Thioridazine; Tranquilizing Agents

1961
A DOUBLE-BLIND COMPARISON OF THIORIDAZINE AND CHLORPROMAZINE.
    The Psychiatric quarterly, 1964, Volume: 38

    Topics: Aggression; Anxiety; Biomedical Research; Chlorpromazine; Depression; Double-Blind Method; Guilt; Hu

1964
A CONTROLLED STUDY OF THE USE OF THIORIDAZINE IN THE TREATMENT OF HYPERACTIVE AND AGGRESSIVE CHILDREN IN A CHILDREN'S PSYCHIATRIC HOSPITAL.
    Canadian Psychiatric Association journal, 1964, Volume: 9

    Topics: Aggression; Biomedical Research; Child; Child Behavior Disorders; Hospitals, Pediatric; Hospitals, P

1964
THE RECOGNITION OF VISUAL SIGNALS IN THE PRESENCE OF VISUAL NOISE BY PSYCHIATRIC PATIENTS.
    The Journal of nervous and mental disease, 1964, Volume: 139

    Topics: Aggression; Bipolar Disorder; Chlorpromazine; Depression; Depressive Disorder; Form Perception; Huma

1964
COMPARISON OF THREE PHENOTHIAZINES ON CHRONIC PSYCHOTIC BEHAVIOR.
    Diseases of the nervous system, 1965, Volume: 26

    Topics: Aggression; Anxiety; Chlorpromazine; Drug Therapy; Fluphenazine; Mental Disorders; Muscle Relaxants,

1965
Behavioural effects of chronic treatment with apomorphine in combination with neuroleptic drugs.
    Journal of neuroscience research, 1980, Volume: 5, Issue:4

    Topics: Aggression; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Chlorpromazine; Drug Thera

1980
Treatment of assaultive hair pulling in a multihandicapped youth.
    Journal of autism and developmental disorders, 1980, Volume: 10, Issue:3

    Topics: Aggression; Ammonia; Aversive Therapy; Behavior Therapy; Blindness; Child; Child Behavior Disorders;

1980
An applied dose-response curve of thioridazine with the mentally retarded: aggressive, self-stimulatory, intellectual, and workshop behaviors--a preliminary report.
    Psychopharmacology bulletin, 1982, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aggression; Behavior; Dose-Response Relationship, Drug; Female; Humans; Intellect

1982
An unusual case of akathisia.
    The American journal of psychiatry, 1979, Volume: 136, Issue:8

    Topics: Adult; Aggression; Akathisia, Drug-Induced; Benztropine; Humans; Intellectual Disability; Male; Psyc

1979
Applying a DRO schedule and compliance training to reduce aggressive and self-injurious behavior in an autistic man: a case report.
    Journal of behavior therapy and experimental psychiatry, 1991, Volume: 22, Issue:4

    Topics: Adult; Aggression; Autistic Disorder; Behavior Therapy; Carbamazepine; Combined Modality Therapy; Ha

1991
Paradoxical response to pindolol treatment for aggression in a patient with Huntington's disease.
    The Journal of clinical psychiatry, 1989, Volume: 50, Issue:6

    Topics: Aggression; Drug Therapy, Combination; Humans; Huntington Disease; Male; Middle Aged; Pindolol; Thio

1989
A critical appraisal of recent drug research in mental retardation: the Coldwater studies.
    Journal of mental deficiency research, 1986, Volume: 30 ( Pt 3)

    Topics: Aggression; Antipsychotic Agents; Attitude of Health Personnel; Discrimination Learning; Humans; Ins

1986
Clonazepam treatment of multi-infarct dementia.
    Journal of geriatric psychiatry and neurology, 1988, Volume: 1, Issue:1

    Topics: Aged; Aggression; Clonazepam; Dementia, Multi-Infarct; Drug Therapy, Combination; Humans; Male; Psyc

1988
Agitated behaviors in the elderly. II. Preliminary results in the cognitively deteriorated.
    Journal of the American Geriatrics Society, 1986, Volume: 34, Issue:10

    Topics: Activities of Daily Living; Aged; Aggression; Cognition Disorders; Confusion; Female; Haloperidol; H

1986
Agitated behaviors in the elderly. II. Preliminary results in the cognitively deteriorated.
    Journal of the American Geriatrics Society, 1986, Volume: 34, Issue:10

    Topics: Activities of Daily Living; Aged; Aggression; Cognition Disorders; Confusion; Female; Haloperidol; H

1986
Agitated behaviors in the elderly. II. Preliminary results in the cognitively deteriorated.
    Journal of the American Geriatrics Society, 1986, Volume: 34, Issue:10

    Topics: Activities of Daily Living; Aged; Aggression; Cognition Disorders; Confusion; Female; Haloperidol; H

1986
Agitated behaviors in the elderly. II. Preliminary results in the cognitively deteriorated.
    Journal of the American Geriatrics Society, 1986, Volume: 34, Issue:10

    Topics: Activities of Daily Living; Aged; Aggression; Cognition Disorders; Confusion; Female; Haloperidol; H

1986
Elevation of thioridazine plasma levels by propranolol.
    The American journal of psychiatry, 1986, Volume: 143, Issue:10

    Topics: Adult; Aggression; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Mental Disord

1986
Clinical behavioral pharmacology: methods for evaluating medications and contingency management.
    Journal of applied behavior analysis, 1985,Spring, Volume: 18, Issue:1

    Topics: Achievement; Adult; Aggression; Attention; Behavior Therapy; Child; Dextroamphetamine; Humans; Intel

1985
Stages of schizophrenic decompensation and reintegration.
    The Journal of nervous and mental disease, 1973, Volume: 157, Issue:3

    Topics: Adult; Affect; Aggression; Antipsychotic Agents; Anxiety; Depression; Desipramine; Fear; Female; Flu

1973
[Clinical expressions of aggressive behavior and their treatment].
    Giornale di psichiatria e di neuropatologia, 1968, Volume: 96, Issue:3

    Topics: Aggression; Carbamazepine; Dibenzazepines; Humans; Mental Disorders; Nitriles; Phenothiazines; Piper

1968
Simultaneous occurrence of renal allograft rejection in one patient and psychosis in another.
    Southern medical journal, 1971, Volume: 64, Issue:5

    Topics: Adult; Aggression; Anxiety; Blood Urea Nitrogen; Depression; Female; Graft Rejection; Hallucinations

1971
[Results of studies on the use of psychotropic drugs in the treatment of encephalopathies following early childhood brain damage].
    Psychiatrie, Neurologie und medizinische Psychologie. Beihefte, 1968, Volume: 8-9

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chronic; Child;

1968
[Animal experimental comparison of tranquilizing effect of doxepine with known psychopharmaceuticals].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:12

    Topics: Aggression; Animals; Anticonvulsants; Behavior, Animal; Chlordiazepoxide; Chlorpromazine; Conditioni

1969
[Intraspecific aggressive behavior induced by apomorphine in the rat].
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Anim

1970
[Therapeutic experiences with oxazepam--a derivative of the benzodiazepine series--in child and adolescent psychiatry].
    Wiener klinische Wochenschrift, 1971, Apr-09, Volume: 83, Issue:14

    Topics: Adolescent; Adolescent Psychiatry; Adult; Aggression; Amitriptyline; Anticonvulsants; Brain Damage,

1971
Effects of centrally active drugs on four models of experimentally-induced aggregession in rodents.
    Life sciences, 1969, Jul-01, Volume: 8, Issue:13

    Topics: Acridines; Aggression; Animals; Antidepressive Agents; Azepines; Chlordiazepoxide; Desipramine; Diaz

1969