thiophenes has been researched along with Osteosarcoma in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bogado, RF; Brassesco, MS; de Oliveira, HF; Pezuk, JA; Tone, LG | 1 |
| Baranski, Z; Booij, TH; Bovée, JV; Cleton-Jansen, AM; Danen, EH; Hogendoorn, PC; Price, LS; van de Water, B | 1 |
| Chen, TH; Chen, WM; Chou, YS; Ke, WT; Lin, YC; Liu, CL; Liu, CY; Wang, JY; Wen, YS; Yang, MH; Yen, CC | 1 |
| Botchkina, G; Formentini, A; Ju, J; Kornmann, M; Song, B; Titmus, MA; Wang, Y | 1 |
| Cooper, RD; Daniel-Issakani, S; Goff, D; Goldstein, E; Gururaja, TL; Hitoshi, Y; Huang, J; Kinoshita, T; McLaughlin, J; Pali, E; Payan, DG; Singh, R; Yung, S | 1 |
| Bertino, JR; Fan, J; Hochhauser, D; Li, WW | 1 |
6 other study(ies) available for thiophenes and Osteosarcoma
| Article | Year |
|---|---|
BI 6727 and GSK461364 suppress growth and radiosensitize osteosarcoma cells, but show limited cytotoxic effects when combined with conventional treatments.
Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Bone Neoplasms; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Osteosarcoma; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Radiation Tolerance; Radiation-Sensitizing Agents; Thiophenes | 2015 |
Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.
Topics: Adaptor Proteins, Signal Transducing; Antibiotics, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Ataxia Telangiectasia Mutated Proteins; Bone Neoplasms; Cell Line, Tumor; Checkpoint Kinase 1; DNA Damage; Doxorubicin; G2 Phase Cell Cycle Checkpoints; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Oligonucleotide Array Sequence Analysis; Osteosarcoma; Phosphorylation; Protein Kinases; RNA Interference; Signal Transduction; Thiophenes; Urea | 2015 |
Cytotoxic mechanism of PLK1 inhibitor GSK461364 against osteosarcoma: Mitotic arrest, apoptosis, cellular senescence, and synergistic effect with paclitaxel.
Topics: Adenosine Triphosphate; Apoptosis; Benzimidazoles; beta-Galactosidase; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Senescence; Computational Biology; Drug Synergism; Enzyme Inhibitors; Flow Cytometry; Humans; Mitosis; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteosarcoma; Paclitaxel; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Small Interfering; Thiophenes | 2016 |
Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Male; Methotrexate; MicroRNAs; Middle Aged; Nuclear Proteins; Osteosarcoma; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetrahydrofolate Dehydrogenase; Thiophenes; Thymidylate Synthase; Transfection; Ubiquitin-Protein Ligases | 2010 |
R-253 disrupts microtubule networks in multiple tumor cell lines.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Flow Cytometry; HeLa Cells; Humans; Lung Neoplasms; Microtubules; Molecular Weight; Osteosarcoma; Pyrimidines; Thiophenes; Thiourea | 2006 |
Overexpression of p21waf1 leads to increased inhibition of E2F-1 phosphorylation and sensitivity to anticancer drugs in retinoblastoma-negative human sarcoma cells.
Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA-Binding Proteins; Doxorubicin; E2F Transcription Factors; E2F1 Transcription Factor; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Methotrexate; Osteosarcoma; Phosphorylation; Quinazolines; Retinoblastoma Protein; Retinoblastoma-Binding Protein 1; Tetracycline; Tetrahydrofolate Dehydrogenase; Thiophenes; Thymidylate Synthase; Transcription Factor DP1; Transcription Factors; Tumor Cells, Cultured | 1997 |