thiophenes has been researched along with Ocular Hypertension in 207 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (1.45) | 18.7374 |
| 1990's | 59 (28.50) | 18.2507 |
| 2000's | 98 (47.34) | 29.6817 |
| 2010's | 43 (20.77) | 24.3611 |
| 2020's | 4 (1.93) | 2.80 |
| Authors | Studies |
|---|---|
| Çakmak, K; Erbil, H; Korkmaz, Ş; Mesci, C | 1 |
| Huang, S; Xing, Y; Zhang, K; Zhu, L | 1 |
| Abe, F; Higuchi, T; Mitsuyama, S | 1 |
| Holló, G; Hutnik, CML; Katsanos, A; Katz, LJ; Konstas, AG; Pfeiffer, N; Quaranta, L; Schmetterer, L; Teus, MA; Uusitalo, H | 1 |
| Adachi, M; Aihara, M; Fukuchi, T; Matsuo, H; Sasaki, N; Togano, T | 1 |
| Andishmand, L; Bavarsad, N; Kouchak, M; Malekahmadi, M; Saki Malehi, A | 1 |
| Biagioli, E; Galli, F; Katsanos, A; Longo, A; Poli, D; Quaranta, L; Riva, I; Rulli, E; Torri, V; Uva, MG; Weinreb, RN | 1 |
| Kim, YY; Na, KH; Park, JH; Yoo, C | 1 |
| Arciniegas-Perasso, CA; Clemente-Tomás, R; Duch-Samper, AM; García-Ibor, F; Hervás-Hernandis, JM; Ruiz-Del Río, N | 1 |
| Biagioli, E; Galli, F; Katsanos, A; Longo, A; Oddone, F; Poli, D; Quaranta, L; Riva, I; Rulli, E; Torri, V; Uva, MG; Weinreb, RN | 1 |
| Bobic-Radovanovic, A; Bozic, M; Knezevic, M; Marjanovic, I; Stojkovic, M | 1 |
| Chung, IY; Han, YS; Kim, GN; Park, JM; Seo, SW; Yoo, JM | 1 |
| Aliyeva, S; Cunha-Vaz, J; Floriani, I; Hoffmann, EM; Miglior, S; Pfeiffer, N; Rulli, E; Torri, V; Zeyen, T | 1 |
| Baser, EF; Gülhan, C; Öztürk, B; Seymenoğlu, G | 1 |
| Akçali, G; Bozkurt, KT; Güney, E; Sezgin Akçay, Bİ; Unlü, C | 1 |
| Campagna, O; Colica, C; Cruciani, F; De Vico, U; Gharbiya, M | 1 |
| Bernardo, FP; Gomes, B; Marques, FP; Portes, AL; Safady, MV; Santhiago, MR; Turiel, PR | 1 |
| He, M; Huang, W; Wang, W | 1 |
| Ghahari, E; Pakravan, M; Rad, SS; Yaseri, M; Yazdani, S | 1 |
| Freeman, K; Jayson, S; Maggs, DJ; Petritz, O; Sanchez-Migallon Guzman, D | 1 |
| Cong, X; Molloy, B | 1 |
| Ahmad, FJ; Anwar, M; Garg, V; Jain, GK; Khar, RK; Talegaonkar, S; Warsi, MH | 1 |
| Agarwal, P; Agarwal, R; Ismail, NM; Kannan Kutty, M; Kapitonova, MY; Razali, N; Salmah Bakar, N; Smirnov, A | 1 |
| García-López, A; Hartleben, C; Jiménez-Román, J; Paczka, JA | 1 |
| Ha, SJ; Seo, du R | 1 |
| Abramson, J; Allbaugh, RA; Alter, H; Amano, C; Amicarella, F; Ara, N; Armengou, L; Asano, N; Bai, SJ; Ben-Shlomo, G; Benoit, E; Bhatnagar, A; Bolli, R; Boulanger, F; Brohawn, P; Brouchkov, A; Buckner, JD; Bukh, J; Buysschaert, C; Carlson, M; Cesarini, C; Cheng, L; Chipinda, I; Cogle, CR; Cooke, JP; Costa, DB; Damotte, D; Das, S; Däster, S; De Chatterjee, A; De Leon, J; Delko, T; Devi, P; Dieu-Nosjean, MC; Droeser, RA; Duarte, T; Ebert, RF; Ecker, AH; Ellis, SG; Eppenberger-Castori, S; Farhoudi, A; Folch, E; Foster, DW; Frasson, D; Fujishima, F; Gangadharan, SP; Gao, W; Germain, C; Glanemann, M; Governa, V; Grant, MB; Hammond, SA; Han, CX; Haspel, RL; He, X; Heberer, M; Henry, TD; Hettick, J; Higgs, BW; Hirt, C; Huang, Y; Huberman, MS; Iezzi, G; Iijima, K; Imatani, A; Ishikawa, N; Izumi, H; Jeon, CO; Jessell, L; Joblin, C; Johnstone, BH; Jose-Cunilleras, E; Joseph, LJ; Jung, WY; Kanazawa, I; Kang, N; Kawaguchi, K; Kawai, K; Kent, MS; Kettelhack, C; Khurshid, SS; Kinney, KA; Kitajima, S; Knockaert, S; Koike, T; Kubo, M; Kuroda, E; Lai, D; Laschke, MW; Lassiter, T; Le, X; Lee, HJ; Lehmann, K; Li, D; Li, F; Li, J; Li, XX; Liu, J; Liu, Y; Liu, YY; Liu, Z; Ma, J; Maejima, R; Majid, A; Makielski, KM; Man, S; Mao, M; Margesin, R; Martincigh, BS; Maruyama, R; Mele, V; Mendez, TL; Menger, MD; Meuleman, P; Miyake, H; Morakinyo, MK; Morimoto, Y; Moussavian, MR; Moyé, L; Myojo, T; Nebiker, CA; Nejad, SA; Nestor, B; Noguchi, T; Oertli, D; Onaka, T; Orozco, A; Oyabu, T; Padovan, E; Pepine, CJ; Perin, EC; Pilleri, P; Prentoe, J; Qiu, P; Rangachari, D; Resende, M; Ríos, J; Robles-Martinez, L; Safarzadeh, MA; Sahraei, E; Salehi, MM; Sasaki, T; Sayre, SL; Schlachtenberger, G; Schutt, RC; Sconocchia, G; Sebastian, Y; Shimada, M; Shimosegawa, T; Siegel, JA; Siegel, PD; Simari, RD; Simoyi, RH; Song, YH; Soysal, SD; Spagnoli, GC; Strongin, R; Sugimoto, T; Tanaka, KI; Tang, XD; Tao, Y; Taylor, DA; Terracciano, L; Thiessen, CE; Tofflemire, KL; Tomonaga, T; Tornillo, L; Traverse, JH; Uno, K; Valge-Archer, V; Validire, P; VanderLaan, PA; Velázquez Moctezuma, R; Verhoye, L; Viu, J; von Heesen, M; von Holzen, U; Wagner, M; Wang, FY; Wang, R; Weixler, B; Whitley, RD; Willerson, JT; Windsor, LC; Wise, E; Wu, FZ; Wu, ZY; Yamamoto, K; Yano, S; Yao, Y; Yatera, K; Yin, Q; Yoshiura, Y; Zhang, DC; Zhang, L; Zhao, DX; Zhou, Y; Zhu, W; Zhu, X; Zierold, C; Zvolensky, MJ | 1 |
| Konstantinidis, A; Kozobolis, V; Labiris, G; Panos, GD | 1 |
| Cong, X; Molloy, BL; Watson, C | 1 |
| Henao-Guerrero, N; Herring, IP; Matusow, RB; Pickett, JP; Werre, SR | 1 |
| Boboridis, KG; Haidich, AB; Kapis, P; Katsanos, A; Konstas, AG; Marinopoulos, K; Mikropoulos, DG; Pagkalidou, E; Panayiotou, D; Quaranta, L; Voudouragkaki, IC | 1 |
| Armour, MD; Dees, DD; Greller, A; Madsen, R; Paglia, D; Spahn, KJ; Wagner, LS | 1 |
| Bell, K; Keicher, A; Lorenz, K; Pfeiffer, N; Renieri, G; Ruckes, C; Thieme, H; Wasielica-Poslednik, J | 1 |
| Besada, E; Frauens, BJ; Shechtman, D | 1 |
| Boyer, S; Gay, D | 1 |
| Kim, JH; Lee, NY; Park, CK; Park, HY | 1 |
| Evans, RM; Mallick, S; Stewart, RH; Vold, SD; Walters, T | 1 |
| Barbosa, WL; Grigera, DE; Hatanaka, M; Jordao, M; Susanna, R | 1 |
| Chalkidou, S; Georgopoulos, G; Halkiadakis, I; Kostakou, A; Markomichelakis, NN; Papakonstantinou, D | 1 |
| Cai, JP; Cheng, JW; Li, Y; Wei, RL; Xi, GL | 1 |
| Eysteinsson, T; Gottfredsdottir, MS; Hardarson, SH; Harris, A; Karlsson, RA; Stefánsson, E; Traustason, S | 1 |
| Galet, VA; Jia, G; Olander, KW; Smugar, SS; Stewart, WC | 1 |
| Chartrand, JP; Hollander, DA; Nixon, DR; Piemontesi, RL; Simonyi, S; Yan, DB | 1 |
| Jamshidian-Tehrani, M; Mehdizadeh, M; Nowroozzadeh, MH | 1 |
| Laxmana Rao, HB; Sekhar, GC | 1 |
| Bournias, TE; Lai, J | 1 |
| Anderson, S; Fortner, J; Luu, KT; Prasanna, G; Vicini, P; Xiang, C; Zhang, EY | 1 |
| Fuchsjäger-Mayrl, G; Garhöfer, G; Georgopoulos, M; Hommer, A; Pemp, B; Schmetterer, L; Vass, C; Weigert, G | 1 |
| Grunden, JW; Kwok, K; Miglior, S | 1 |
| Civiale, C; Cunsolo, V; Foti, S; Muccilli, V; Saletti, R; Zammataro, A | 1 |
| Gugleta, K | 1 |
| Calvo-González, C; Fernández-Vidal, A; García-Feijoó, J; García-Sánchez, J; Martínez-de-la-Casa, JM; Méndez-Hernández, C; Sáenz-Francés, F | 1 |
| Beaver, Y; Borchardt, AJ; Cayanan, CS; Clark, AF; Cook, TG; Cramp, J; Davis, RL; Gardiner, EM; Hellberg, MR; Kahraman, M; McLaughlin, MA; Noble, SA; Prins, TJ; Shiau, AK | 1 |
| Adamsons, IA; Getson, AJ; Hewitt, DJ; Ho, TW; Laurence, JK; Lines, CR; Shedden, A | 1 |
| Bastien, NR; Behki, R; Boucher, S; Crichton, AC; Harasymowycz, P; Hutnik, CM; Ibrahim, F; Liao, C; Rifkind, AW; Sampalis, JS; Solomon, L | 1 |
| Hendrikse, F; Peeters, A; Prins, MH; Schouten, JS; Webers, CA | 1 |
| David, R; Kurtz, S; Newman, H | 1 |
| Benedini, F; Biondi, S; Cecchi, A; Formicola, G; Masini, E; Mincione, F; Pacileo, I; Scozzafava, A; Supuran, CT; Temperini, C | 1 |
| Araie, M; Kitazawa, Y | 1 |
| Fan, S; Gangahar, C; Gulati, V; Maslonka, MA; Toris, CB; Zhao, M | 1 |
| Dot, C; El Chehab, H; Giraud, JM; Le Corre, A; Ract-Madoux, G; Swalduz, B | 1 |
| Inoue, K; Shiokawa, M; Soeda, S; Sugahara, M; Tomita, G; Wakakura, M | 1 |
| Larsson, LI; Mishima, HK; Orzalesi, N; Rossetti, L; Takamatsu, M | 1 |
| Bron, AM; Emmerich, KH | 1 |
| Adamsons, I; Cunha-Vaz, J; Miglior, S; Pfeiffer, N; Torri, V; Zeyen, T | 4 |
| Bron, A | 1 |
| Bottoli, A; Fogagnolo, P; Fumagalli, E; Invernizzi, T; Orzalesi, N; Rossetti, I | 1 |
| Davani, S; Delbosc, B; Kantelip, JP; Royer, B | 1 |
| Berdeaux, G; Berto, P; Gouveia Pinto, C; Le Pen, C; Rouland, JF | 1 |
| Day, DG; Leech, J; Schacknow, PN; Sharpe, ED; Stewart, JA; Stewart, WC; Wand, M | 1 |
| Boyle, DR; Cassel, DA; DeLucca, PT; Fletcher, CA; Greff, LJ; Johnson-Pratt, LR; Kolodny, AH; Polis, AB; Sall, KN; Skobieranda, F | 1 |
| Amaral, M; Arieta, C; Crosta, C; de Carvalho Moreira Filho, D; José, N; Matuda, E | 1 |
| Bottoli, A; Fogagnolo, P; Fumagalli, E; Orzalesi, N; Rossetti, L | 1 |
| Brignoli, R; Mermoud, A; Ravinet, E | 1 |
| Hommer, A; Kapik, B; Shams, N | 1 |
| Flammer, J; Gugleta, K; Orgül, S | 1 |
| Czechowicz-Janicka, K; Kałuzny, J; Kałuzny, JJ; Krajewska, M; Leech, JN; Orzalkiewicz, A; Stewart, JA; Stewart, WC; Szaflik, J; Zaleska, A | 1 |
| Houliara, D; Konstas, AG; Papapanos, P; Stewart, WC; Tersis, I | 1 |
| Mozaffari, E; Reardon, G; Schwartz, GF | 1 |
| Nesher, R; Ticho, U | 1 |
| Chen, YF; Hung, PT; Yang, CH | 1 |
| Bernstein, P; Coleman, AL; Lerner, F; Whitcup, SM | 1 |
| Adamsons, IA; Airaksinen, PJ; Fechtner, RD; Getson, AJ; Lines, CR | 1 |
| Amoako-Mensah, T; Buehl, W; Eichler, HG; Fuchsjäger-Mayrl, G; Georgopoulos, M; Kircher, K; Rainer, G; Schmetterer, L; Vass, C; Wally, B | 1 |
| Hara, A; Maeda, K; Matsubara, M; Nakai, Y; Sawada, A; Yamamoto, T | 1 |
| Day, DG; Holmes, KT; Jenkins, JN; Stewart, JA; Stewart, WC | 1 |
| Feldman, RM; Sheu, WP; Shin, DH | 1 |
| Cassel, DA; DeLucca, PT; Hustad, CM; Kolodny, AH; Skobieranda, F; Solish, AM | 1 |
| Fechtner, RD; Henry, C; Hughes, B; Lee, DA; Terry, S; Whitson, JT | 1 |
| Camras, CB; Toris, CB; Yablonski, ME; Zhan, GL | 1 |
| Arias Puente, A; Carrasco Font, C; García Sáenz, MC; Villarejo Díaz-Maroto, I | 1 |
| Beischel, CJ; Day, DG; Rhodes, JS; Sharpe, ED; Stewart, JA; Stewart, WC | 1 |
| Christodoulakis, E; Konstas, AG; Kozobolis, VP; Lallos, N; Stewart, JA; Stewart, WC | 1 |
| Sheu, WP; Susanna, R; Sussana, R | 1 |
| Călugăru, D; Călugăru, M | 1 |
| Langenbucher, A; Mardin, CY; Martus, P; Schlötzer-Schrehardt, U; Viestenz, A | 1 |
| Tressler, CS | 1 |
| Kaiserman, I; Kaiserman, N; Nakar, S; Vinker, S | 1 |
| Lanzl, I; Nagel, E; Vilser, W | 1 |
| Adamsons, IA; Fechtner, RD; Lines, CR; McCarroll, KA | 1 |
| Quigley, HA | 1 |
| Adamsons, IA; Arango, S; Assaid, CA; Getson, AJ; Mills, MD; Ott, EZ | 1 |
| Aggermann, T; Buehl, W; Eichler, HG; Fuchsjäger-Mayrl, G; Kolodjaschna, J; Polska, E; Rainer, G; Schmetterer, L; Vass, C; Wally, B; Weigert, G | 1 |
| Antohi, I; Chiseliţă, D; Danielescu, C; Medvichi, R | 1 |
| Batista, WD; da Silva, LJ; Figueiredo, CR; Franklin, LM; Netto, JA; Suzuki, ER | 1 |
| Goñi, FJ | 1 |
| Frampton, JE; Perry, CM | 1 |
| Ermis, SS; Inan, UU; Ozturk, F | 1 |
| Andreo, EG; Arcieri, ES; Arcieri, RS; Finotti, IG; Pereira, AC; Sá Filho, WF | 1 |
| Buehl, W; Georgopoulos, M; Heinzl, H; Menapace, R; Rainer, G; Wirtitsch, MG | 1 |
| Craven, ER; Katz, LJ; Simmons, ST | 1 |
| Henry, JC; Nelson, LA; Sharpe, ED; Sonty, S; Stewart, JA; Stewart, WC; Weiss, MJ | 1 |
| Konstas, AG; Kruft, B; Nelson, LA; Stewart, WC | 1 |
| Efremova, R; Konstas, AG; Kozobolis, VP; Makridaki, I; Stewart, WC; Tsironi, S | 1 |
| Comez, A; Dogan, OK; Karacan, O; Oral, Y; Ozkurt, Y | 1 |
| Cvenkel, B; Nelson, LA; Stewart, JA; Stewart, WC | 1 |
| Bastien, NR; Koulis, T; Lesk, MR; Sampalis, F; Sampalis, JS | 1 |
| Evans, D; Fung, KH; Lupinacci, AP; Netland, PA; Zhao, Y | 1 |
| Strahlman, E; Tipping, R; Vogel, R | 2 |
| Palmberg, P | 1 |
| Cyrlin, M; Deasy, D; Esposito, D; Fazio, R; Lippa, EA; Panebianco, D; Shields, MB; Wilkerson, M; Yablonski, M | 1 |
| Brechue, WF; Maren, TH | 1 |
| Bosc, JM; Bron, AM; George, JL; Greve, EL; Gunning, FP; Lesure, P; Royer, JG; Sirbat, D | 1 |
| Barber, BL; Santanello, NC | 1 |
| Ballantyne, C; Gray, TB; Simpson, AJ | 1 |
| Clineschmidt, CM; Strahlman, ER; Tipping, R; Vogel, R | 1 |
| Brinchman-Hansen, O; Heijl, A; Puustjärvi, T; Strahlman, E; Sverrisson, T; Tipping, R | 1 |
| Conroy, CW; Levy, NS; Maren, TH; Wynns, GC | 1 |
| Balfour, JA; Wilde, MI | 1 |
| Brooks, AM; Gillies, WE | 1 |
| Allingham, RR; Choudhri, SA; Cox, T; Damji, KF; Herndon, LW; Shields, MB | 1 |
| Baltatzis, S; Kokolakis, SN; Ladas, ID; Panagiotidis, D; Theodossiadis, GP; Zafirakis, P | 1 |
| Hong, PH; Krupin, T; Rosenberg, LF; Ruderman, JM; Tang, LQ | 1 |
| Barisani, T; Baumgartner, I; Biowski, R; Hommer, A; Kaminski, S; Koyuncu, D | 1 |
| Adamsons, I; Snyder, E; Strohmaier, K | 1 |
| Adamsons, I; Clineschmidt, C; Laibovitz, R; Polis, A; Shedden, A; Taylor, J | 1 |
| Adamsons, I; Ghosh, K; Horwitz, B; Khosrof, SA; Lass, JH; Laurence, JK | 1 |
| Silver, LH | 2 |
| Hustead, JD | 1 |
| Adamsons, IA; Boyle, JE; Ghosh, K; Gieser, DK | 2 |
| Adamsons, I; DuBiner, H; Snyder, E; Strohmaier, K | 2 |
| Adamsons, IA; Clineschmidt, CM; Snyder, E; Williams, RD | 2 |
| Lukaris, A; Roberts-Harry, TJ; Rogers, ZA; Sells, M; Zohdy, GA | 1 |
| Brubaker, RF; Larsson, LI; Maus, TL; Wayman, LL | 1 |
| Gerdtham, U; Jönsson, L; Kobelt, G; Krieglstein, GK | 1 |
| Adamsons, IA; Boyle, JE; Ostrov, CS; Polis, A | 1 |
| Adamsons, IA; Hutzelmann, JE; Michael, AJ; Polis, AB | 1 |
| Adamsons, I; Hutzelmann, J; Owens, S; Shedden, A; Vargas, E | 1 |
| Jörg, KM; Lachmann, C; Trinkmann, R | 1 |
| Güler, C; Kimal Arici, M; Topalkara, A | 1 |
| Bron, A; Chapard, J; Creuzot-Garcher, C; D'Athis, P; Guerzider, V | 1 |
| Hartenbaum, D; Maloney, S; Orillac, R; Sharpe, E; Vacarelli, L; Wilson, H | 1 |
| Gormley, GJ; Hartenbaum, D; Liss, C; Maloney, S; Vaccarelli, L; Wilson, H | 1 |
| Adamsons, I; Gross, R; Pearson, J; Rusk, C; Sverrisson, T | 1 |
| Herbort, CP; Mermoud, A; Schnyder, CC; Tran, VT | 1 |
| Findl, O; Georgopoulos, M; Menapace, R; Rainer, G; Schmetterer, K; Vass, C | 1 |
| Apatachioae, I; Chiselita, D; Poiata, I | 1 |
| Emmerich, KH | 1 |
| Sall, K | 1 |
| Amyot, M; Boisjoly, HM; Charest, M; Giasson, CJ; Lesk, MR; Nguyen, TQ | 1 |
| Connor, TB; Dev, S; Han, DP; Mieler, WF; Mittra, RA; Pollack, JS; Pulido, JS | 1 |
| Samuelson, TW; Simmons, ST | 1 |
| O'Donoghue, EP | 1 |
| Chopra, H; Day, DG; Holmes, KT; Kolker, AE; Konstas, AG; Lee, WH; Rieser, JC; Sharpe, ED; Stewart, WC | 1 |
| Day, DG; Harbin, TS; Holmes, KT; Pastor, SA; Sharpe, ED; Stewart, JA; Stewart, WC | 1 |
| Autelitano, A; Bottoli, A; Invernizzi, T; Orzalesi, N; Rossetti, L | 1 |
| Kobayashi, M; Naito, K | 1 |
| Bjarnadóttir, G; Gudmundsdóttir, E; Gudmundsdóttir, G; Loftsson, T; Masson, M; Sigurjónsdóttir, JF; Stefánsson, E | 1 |
| Bergua, A; Horn, FK; Jünemann, A; Korth, M; Velten, IM | 1 |
| Findl, O; Georgopoulos, M; Heinze, G; Kiss, B; Menapace, R; Rainer, G | 1 |
| Aurilia, P; Boles Carenini, B; Durante, A; Guarnaccia, G | 1 |
| Simmons, ST | 1 |
| Findl, O; Georgopoulos, M; Kiss, B; Menapace, R; Petternel, V; Rainer, G | 1 |
| Friren, B; Michaud, JE | 1 |
| Krueger, RR; Nagy, ZZ; Süveges, I; Szabó, A | 1 |
| Andreanos, D; Dimitrakoulias, N; Kandarakis, A; Mylopoulos, N; Petounis, A | 1 |
| Jurkowska-Dudzińska, J; Kawa, P; Zagórski, Z; Zarnowski, T | 1 |
| Chang, HW; Tsai, JC | 1 |
| Easthope, SE; Perry, CM | 1 |
| Halper, LK; Hartenbaum, D; Johnson-Pratt, L; Polis, A; Stewart, WC | 1 |
| Béchetoille, A; Brunner-Ferber, FL; Buntinx, A; Clineschmidt, C; Gerling, J; Grehn, F; Gunning, F; Holder, D; Lippa, EA; Pfeiffer, N | 1 |
| Camras, CB; Deasy, D; Framm, L; Lippa, EA; Lustgarten, J; Payne, JE; Podos, SM; Serle, JB | 1 |
| Halczenko, W; Hartman, GD; Mallorga, PJ; Michelson, SR; Randall, WC; Schwam, H; Smith, RL; Sondey, JM; Sugŕue, MF | 1 |
| Carlson, LE; Ehinger, B; Eriksson, LO; Finnström, K; Holmin, C; Lippa, EA; Nilsson, SE; Nyman, K; Raitta, C; Ringvold, A | 1 |
| Béchetoille, A; Gerling, J; Grehn, F; Greve, E; Gunning, F; Jaquet-Müller, F; Lippa, EA; Pfeiffer, N | 1 |
| Graham, SL; Hudcosky, RJ; Michelson, SR; Scholz, TH; Schwam, H; Shepard, KL; Smith, AM; Smith, RL; Sondey, JM; Strohmaier, KM | 1 |
| Aasved, H; Airaksinen, PJ; Alm, A; Bertelsen, T; Calissendorff, B; Dithmer, O; Eriksson, LO; Gustad, L; Høvding, G; Lippa, EA | 1 |
| Bénichou, C; Bron, A; Clineschmidt, C; Flament, J; Gunning, F; Lesure, P; Lippa, EA; Panebianco, D; Royer, J; Sirbat, D | 1 |
| Deasy, DA; Epstein, DL; Higginbotham, EJ; Holder, DJ; Kass, MA; Lippa, EA; Schuman, JS; Shaw, B; Skuta, GL; Weinreb, RN | 1 |
| Baldwin, JJ; Mallorga, P; Ponticello, GS; Schwam, H; Sugrue, MF | 1 |
| Camras, CB; Lippa, EA; Lustgarten, JS; Panebianco, DL; Podos, SM; Serle, JB | 1 |
| Garus, H; Grehn, F; Hennekes, R; Pfeiffer, N | 1 |
| Brunner-Ferber, FL; Garus, H; Grehn, F; Hennekes, R; Lippa, EA; Pfeiffer, N | 1 |
| Bechetoille, A; Brunner-Ferber, F; Diestelhorst, M; Krieglstein, GK; Lippa, E | 1 |
| Baldwin, JJ; Christy, ME; Gautheron, P; Grove, J; Mallorga, P; Ponticello, GS; Schwam, H; Sugrue, MF; Viader, MP | 1 |
| Batenhorst, RL; Higginbotham, EJ; Kass, MA; Lippa, EA; Panebianco, DL; Wilensky, JT | 1 |
| Anderson, PS; Baldwin, JJ; Best, DB; Christy, ME; Freedman, MB; Gautheron, P; Graham, SL; Habecker, CN; Hoffman, JM; Shepard, KL | 1 |
| Bron, AM; Brunner-Ferber, FL; Feicht, BI; Hofmann, HM; Lippa, EA; Panebianco, DL; Royer, JG; Von Denffer, HA | 1 |
| Kass, MA | 1 |
17 review(s) available for thiophenes and Ocular Hypertension
| Article | Year |
|---|---|
The efficacy of the fixed combination of latanoprost and timolol versus other fixed combinations for primary open-angle glaucoma and ocular hypertension: A systematic review and meta-analysis.
Topics: Antihypertensive Agents; Bimatoprost; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2020 |
Dorzolamide/Timolol Fixed Combination: Learning from the Past and Looking Toward the Future.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2021 |
Efficacy and tolerability of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure: a meta-analysis of randomized controlled trials.
Topics: Antihypertensive Agents; Drug Tolerance; Female; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2013 |
Efficacy and tolerability of latanoprost compared to dorzolamide combined with timolol in the treatment of patients with elevated intraocular pressure: a meta-analysis of randomized, controlled trials.
Topics: Antihypertensive Agents; Drug Combinations; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2009 |
Topical carbonic anhydrase inhibitors and visual function in glaucoma and ocular hypertension.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Ocular Hypertension; Sulfonamides; Thiazines; Thiophenes; Visual Fields | 2010 |
The effect of latanoprost on circadian intraocular pressure.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2002 |
Latanoprost versus combined timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2002 |
[Comparison of latanoprost monotherapy with timolol-dorzolamide combination in patients with open-angle glaucoma or ocular hypertension].
Topics: Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2002 |
Four years later: a clinical update on latanoprost.
Topics: Antihypertensive Agents; Aqueous Humor; Blood Flow Velocity; Circadian Rhythm; Clinical Trials as Topic; Drug Therapy, Combination; Eye; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol | 2003 |
[Timolol topical ophthalmic combination].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Topical dorzolamide 2%/timolol 0.5% ophthalmic solution: a review of its use in the treatment of glaucoma and ocular hypertension.
Topics: Drug Combinations; Glaucoma; Humans; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Vision, Ocular | 2006 |
Efficacy and safety of brimonidine and dorzolamide for intraocular pressure lowering in glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Clinical Trials as Topic; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 2007 |
Meta-analysis of 24-hour intraocular pressure studies evaluating the efficacy of glaucoma medicines.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2008 |
A topical carbonic anhydrase inhibitor finally arrives.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1995 |
Dorzolamide. A review of its pharmacology and therapeutic potential in the management of glaucoma and ocular hypertension.
Topics: Absorption; Aging; Animals; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Controlled Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Quality of Life; Regional Blood Flow; Retina; Sulfonamides; Thiophenes; Tissue Distribution | 1997 |
[Pharmacological profiles of the potent carbonic anhydrase inhibitor dorzolamide hydrochloride, a topical antiglaucoma agent].
Topics: Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Eye; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes | 2000 |
Topical bimatoprost: a review of its use in open-angle glaucoma and ocular hypertension.
Topics: Administration, Topical; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Conjunctival Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma, Open-Angle; Intraocular Pressure; Latanoprost; Lipids; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2002 |
140 trial(s) available for thiophenes and Ocular Hypertension
| Article | Year |
|---|---|
Comparing the effects and safety of dorzolamide hydrochloride + timolol maleate versus brimonidine after neodymium-doped yttrium aluminium garnet laser capsulotomy posterior capsule opacification.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Capsule Opacification; Glaucoma; Humans; Intraocular Pressure; Lasers, Solid-State; Neodymium; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Yttrium | 2022 |
Additive effects and safety of fixed combination therapy with 1% brinzolamide and 0.5% timolol versus 1% dorzolamide and 0.5% timolol in prostaglandin-treated glaucoma patients.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Follow-Up Studies; Glaucoma, Open-Angle; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins, Synthetic; Sulfonamides; Thiazines; Thiophenes; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Dorzolamide nanoliposome as a long action ophthalmic delivery system in open angle glaucoma and ocular hypertension patients.
Topics: Antihypertensive Agents; Cornea; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Liposomes; Nanoparticles; Ocular Hypertension; Ophthalmic Solutions; Permeability; Sulfonamides; Thiophenes; Time Factors | 2018 |
The Glaucoma Italian Pediatric Study (GIPSy): 1-Year Results.
Topics: Antihypertensive Agents; Child; Child, Preschool; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Italy; Latanoprost; Male; Ocular Hypertension; Prognosis; Prospective Studies; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome | 2017 |
The Glaucoma Italian Pediatric Study (GIPSy): 3-Year Results.
Topics: Antihypertensive Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Italy; Latanoprost; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome | 2018 |
The Heidelberg retina tomograph ancillary study to the European glaucoma prevention study: study design and baseline factors.
Topics: Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmoscopy; Optic Disk; Optic Nerve Diseases; Research Design; Sulfonamides; Thiophenes; Tomography; Tonometry, Ocular; Visual Acuity; Visual Fields | 2013 |
Comparison of dorzolamide/timolol versus brimonidine/timolol fixed combination therapy in the management of steroid-induced ocular hypertension.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Diabetic Retinopathy; Drug Combinations; Female; Glucocorticoids; Humans; Intraocular Pressure; Intravitreal Injections; Macular Edema; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Triamcinolone Acetonide | 2015 |
The safety and efficacy of brinzolamide 1%/timolol 0.5% fixed combination versus dorzolamide 2%/timolol 0.5% in patients with open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Preference; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 2013 |
Effect of early treatment with aqueous suppressants on Ahmed glaucoma valve implantation outcomes.
Topics: Adult; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma; Glaucoma Drainage Implants; Humans; Intraocular Pressure; Logistic Models; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Acuity | 2014 |
Efficacy and tolerability of fixed-combination bimatoprost/timolol versus fixed-combination dorzolamide/brimonidine/timolol in patients with primary open-angle glaucoma or ocular hypertension: a multicenter, prospective, crossover study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Circadian Rhythm; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2014 |
Comparison of dorzolamide/timolol vs brinzolamide/brimonidine fixed combination therapy in the management of primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Preventive Dorzolamide-Timolol for Rising Intraocular Pressure During Steep Trendelenburg Position Surgery.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Combinations; Eye; Female; Head-Down Tilt; Humans; Intraocular Pressure; Intraoperative Complications; Laparoscopy; Male; Middle Aged; Monitoring, Intraoperative; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2016 |
Effects of perioperative topical dorzolamide hydrochloride-timolol maleate administration on incidence and severity of postoperative ocular hypertension in dogs undergoing cataract extraction by phacoemulsification.
Topics: Animals; Antihypertensive Agents; Cataract Extraction; Dog Diseases; Dogs; Drug Combinations; Ocular Hypertension; Perioperative Care; Postoperative Complications; Sulfonamides; Thiophenes; Timolol | 2016 |
24-Hour Efficacy and Ocular Surface Health with Preservative-Free Tafluprost Alone and in Conjunction with Preservative-Free Dorzolamide/Timolol Fixed Combination in Open-Angle Glaucoma Patients Insufficiently Controlled with Preserved Latanoprost Monothe
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Prostaglandins F; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma.
Topics: Acetazolamide; Aged; Antihypertensive Agents; Dexamethasone; Drug Combinations; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preoperative Care; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Treatment Outcome | 2017 |
A one-week comfort study of BID-dosed brinzolamide 1%/timolol 0.5% ophthalmic suspension fixed combination compared to BID-dosed dorzolamide 2%/timolol 0.5% ophthalmic solution in patients with open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol | 2008 |
An eight-week, multicentric, randomized, interventional, open-label, phase 4, parallel comparison of the efficacy and tolerability of the fixed combination of timolol maleate 0.5%/brimonidine tartrate 0.2% versus fixed combination of timolol maleate 0.5%/
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult | 2008 |
Efficacy and safety of latanoprost in eyes with uveitic glaucoma.
Topics: Adult; Antihypertensive Agents; Drug Combinations; Female; Follow-Up Studies; Glaucoma; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Recurrence; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Uveitis, Anterior; Uveitis, Intermediate; Visual Acuity | 2009 |
Dorzolamide-timolol combination and retinal vessel oxygen saturation in patients with glaucoma or ocular hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Oximetry; Oxygen; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Young Adult | 2009 |
Three-month, randomized, parallel-group comparison of brimonidine-timolol versus dorzolamide-timolol fixed-combination therapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Osmolar Concentration; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol | 2009 |
Brimonidine tartrate 0.15%, dorzolamide hydrochloride 2%, and brinzolamide 1% compared as adjunctive therapy to prostaglandin analogs.
Topics: Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Single-Blind Method; Sulfonamides; Thiazines; Thiophenes; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Effect of dorzolamide and timolol on ocular pressure: blood flow relationship in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Interferometry; Intraocular Pressure; Laser-Doppler Flowmetry; Lasers; Male; Middle Aged; Ocular Hypertension; Optic Disk; Optic Nerve Diseases; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2010 |
Efficacy and safety of fixed combinations of latanoprost/timolol and dorzolamide/timolol in open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 2010 |
Comparison of ocular hypotensive actions of fixed combinations of brimonidine/timolol and dorzolamide/timolol.
Topics: Aged; Aged, 80 and over; Algorithms; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Dosage Forms; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2010 |
Comparison of the efficacy and tolerability of preservative-free and preservative-containing formulations of the dorzolamide/timolol fixed combination (COSOPT™) in patients with elevated intraocular pressure in a randomized clinical trial.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2010 |
Intraocular pressure changes in the contralateral eye after topical treatment: does an "ophthalmotonic consensual reaction" exist?
Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cohort Studies; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins, Synthetic; Sulfonamides; Thiophenes; Timolol | 2010 |
[Double-masked, phase III comparative study of the combination ophthalmic solution of the 1% dorzolamide hydrochloride/0.5% timolol maleate (MK-0507A) in patients with glaucoma and ocular hypertension].
Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2011 |
Diurnal and nocturnal variations in aqueous humor dynamics of patients with ocular hypertension undergoing medical therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cornea; Cross-Over Studies; Double-Blind Method; Female; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sphygmomanometers; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography | 2012 |
[Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections].
Topics: Acetazolamide; Aged; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Brimonidine Tartrate; Chemoprevention; Clonidine; Drug Combinations; Female; Humans; Hypotonic Solutions; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2012 |
Three-month evaluation of dorzolamide hydrochloride/timolol maleate fixed-combination eye drops versus the separate use of both drugs.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Medication Adherence; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Tonometry, Ocular | 2012 |
The European glaucoma prevention study design and baseline description of the participants.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Research Design; Safety; Sulfonamides; Thiophenes; Visual Acuity; Visual Field Tests; Visual Fields | 2002 |
Comparison of latanoprost, brimonidine and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2002 |
Cost-minimisation study of dorzolamide versus brinzolamide in the treatment of ocular hypertension and primary open-angle glaucoma: in four European countries.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Economics, Pharmaceutical; Europe; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes | 2003 |
Timolol 0.5%/dorzolamide 2% fixed combination vs timolol maleate 0.5% and unoprostone 0.15% given twice daily to patients with primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cross-Over Studies; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Acuity | 2003 |
Dorzolamide/timolol combination versus concomitant administration of brimonidine and timolol: six-month comparison of efficacy and tolerability.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 2003 |
Dorzolamide X apraclonidine in the prevention of the intraocular pressure spike after Nd : YAG laser posterior capsulotomy.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Clonidine; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Time Factors | 2002 |
The effect of latanoprost, brimonidine, and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2003 |
Unoprostone as adjunctive therapy to timolol: a double masked randomised study versus brimonidine and dorzolamide.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Chemotherapy, Adjuvant; Dinoprost; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2003 |
Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pilocarpine; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Twenty-four-hour diurnal curve comparison of commercially available latanoprost 0.005% versus the timolol and dorzolamide fixed combination.
Topics: Adult; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
A six-week, parallel, randomized, double-blind study comparing the efficacy and safety of the 0.5% timolol/2.0% MK-507 combination b.i.d. to the concomitant administration of 0.5% timolol b.i.d. and 2.0% MK-507 b.i.d.
Topics: Adult; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Statistics, Nonparametric; Sulfonamides; Thiophenes; Timolol | 2003 |
A 3-month randomized controlled trial of bimatoprost (LUMIGAN) versus combined timolol and dorzolamide (Cosopt) in patients with glaucoma or ocular hypertension.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol | 2003 |
Efficacy and tolerability of the dorzolamide 2%/timolol 0.5% combination (COSOPT) versus 0.005% (XALATAN) in the treatment of ocular hypertension or glaucoma: results from two randomized clinical trials.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Short-term ocular tolerability of dorzolamide 2% and brinzolamide 1% vs placebo in primary open-angle glaucoma and ocular hypertension subjects.
Topics: Adult; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pain; Pain Measurement; Prospective Studies; Severity of Illness Index; Sulfonamides; Thiazines; Thiophenes | 2004 |
Efficacy and safety of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Dorzolamide/Timolol fixed combination versus concomitant administration of brimonidine and timolol in patients with elevated intraocular pressure: a 3-month comparison of efficacy, tolerability, and patient-reported measures.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Comparison of the safety and efficacy of dorzolamide 2% and brimonidine 0.2% in patients with glaucoma or ocular hypertension.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 2004 |
Effects on aqueous flow of dorzolamide combined with either timolol or acetazolamide.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Antihypertensive Agents; Aqueous Humor; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Manometry; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2004 |
[Efficiency of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers].
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quality of Life; Quinoxalines; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome | 2004 |
Brimonidine purite 0.15% versus dorzolamide 2% each given twice daily to reduce intraocular pressure in subjects with open angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes | 2004 |
Daytime diurnal curve comparison between the fixed combinations of latanoprost 0.005%/timolol maleate 0.5% and dorzolamide 2%/timolol maleate 0.5%.
Topics: Adult; Aged; Antihypertensive Agents; Chronotherapy; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2004 |
Comparison of latanoprost with fixed-combination dorzolamide and timolol in adult patients with elevated intraocular pressure: an eight-week, randomized, open-label, parallel-group, multicenter study in Latin America.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2004 |
[Impact of prostaglandin-F(2alpha)-analogues and carbonic anhydrase inhibitors on central corneal thickness -- a cross-sectional study on 403 eyes].
Topics: Acetazolamide; Administration, Topical; Adult; Aged; Carbonic Anhydrase Inhibitors; Cloprostenol; Collagen; Cornea; Corneal Topography; Cross-Sectional Studies; Dinoprost; Drug Therapy, Combination; Extracellular Matrix; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Travoprost; Ultrasonography | 2004 |
Results of the European Glaucoma Prevention Study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Disease Progression; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quality Assurance, Health Care; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 2005 |
Dorzolamide influences the autoregulation of major retinal vessels caused by artificial intraocular pressure elevation in patients with POAG: a clinical study.
Topics: Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Female; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Muscle, Smooth, Vascular; Ocular Hypertension; Ophthalmic Solutions; Retinal Artery; Sulfonamides; Thiophenes; Vasodilation | 2005 |
Efficacy of the dorzolamide/timolol fixed combination versus latanoprost in the treatment of ocular hypertension or glaucoma: combined analysis of pooled data from two large randomized observer and patient-masked studies.
Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
A randomized trial assessing dorzolamide in patients with glaucoma who are younger than 6 years.
Topics: Antihypertensive Agents; Child, Preschool; Double-Blind Method; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
Effect of dorzolamide and timolol on ocular blood flow in patients with primary open angle glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Choroid; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Regional Blood Flow; Regression Analysis; Retinal Vessels; Sulfonamides; Thiophenes; Timolol | 2005 |
Comparative analysis of the efficacy and safety of latanoprost, travoprost and the fixed combination timolol-dorzolamide; a prospective, randomized, masked, cross-over design study.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Latanoprost; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2005 |
Comparison of the efficacy and safety of travoprost with a fixed-combination of dorzolamide and timolol in patients with open-angle glaucoma or ocular hypertension.
Topics: Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Travoprost | 2006 |
Predictive factors for open-angle glaucoma among patients with ocular hypertension in the European Glaucoma Prevention Study.
Topics: Antihypertensive Agents; Disease Progression; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prognosis; Proportional Hazards Models; Risk Factors; Sulfonamides; Thiophenes; Visual Acuity | 2007 |
Central corneal thickness in the European Glaucoma Prevention Study.
Topics: Adult; Age Factors; Aged; Cornea; Diabetes Complications; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sex Factors; Sulfonamides; Thiophenes; Ultrasonography | 2007 |
Comparison of the ocular hypotensive effects of bimatoprost and timolol-dorzolamide combination in patients with elevated intraocular pressure: a 6-month study.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes; Timolol | 2007 |
Comparing the fixed combination brimonidine-timolol versus fixed combination dorzolamide-timolol in patients with elevated intraocular pressure.
Topics: Aged; Brimonidine Tartrate; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2007 |
Intraocular pressure rise after primary posterior continuous curvilinear capsulorhexis with a fixed dorzolamide-timolol combination: randomized safety study with intraindividual comparison using an angulated and a nonangulated intraocular lens.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Capsulorhexis; Cataract; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Middle Aged; Ocular Hypertension; Postoperative Complications; Prospective Studies; Prosthesis Design; Sulfonamides; Thiophenes; Timolol | 2007 |
Success rates for switching to dorzolamide/timolol fixed combination in timolol responders who are insufficiently controlled by latanoprost monotherapy.
Topics: Aged; Antihypertensive Agents; Cohort Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Satisfaction; Prospective Studies; Quality of Life; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Treatment Outcome | 2008 |
Comparison of the 24-hour intraocular pressure-lowering effects of latanoprost and dorzolamide/timolol fixed combination after 2 and 6 months of treatment.
Topics: Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Therapeutic Equivalency; Thiophenes; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2008 |
Comparison of the effects of dorzolamide-timolol fixed combination and brimonidine on intraocular pressure after phacoemulsification surgery.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Postoperative Care; Postoperative Complications; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
Dorzolamide/timolol fixed combination versus latanoprost/timolol fixed combination in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2008 |
Effectiveness and safety of dorzolamide-timolol alone or combined with latanoprost in open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Canada; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
Comparison of twice-daily and three-times-daily dosing of dorzolamide in ocular hypertension and primary open-angle glaucoma patients treated with latanoprost.
Topics: Antihypertensive Agents; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 2008 |
A double-masked, randomized 1-year study comparing dorzolamide (Trusopt), timolol, and betaxolol. International Dorzolamide Study Group.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1995 |
Four-week safety and efficacy study of dorzolamide, a novel, active topical carbonic anhydrase inhibitor.
Topics: Administration, Topical; Adult; Aged; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Count; Cornea; Double-Blind Method; Drug Tolerance; Endothelium, Corneal; Erythrocytes; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes | 1993 |
Two topical carbonic anhydrase inhibitors sezolamide and dorzolamide in Gelrite vehicle: a multiple-dose efficacy study.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Delivery Systems; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Polysaccharides, Bacterial; Sulfonamides; Thiophenes | 1993 |
Relating spontaneous adverse experience reports to scores on a questionnaire querying tolerability.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol | 1995 |
A six-week dose-response study of the ocular hypotensive effect of dorzolamide with a one-year extension. Dorzolamide Dose-Response Study Group.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 1996 |
A controlled clinical trial of dorzolamide: a single-centre subset of a multicentre study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1996 |
The use of dorzolamide and pilocarpine as adjunctive therapy to timolol in patients with elevated intraocular pressure. The Dorzolamide Additivity Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Muscarinic Agonists; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Pilot Projects; Safety; Sulfonamides; Thiophenes; Timolol | 1996 |
A comparison of dorzolamide and timolol in patients with pseudoexfoliation and glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1997 |
A clinical trial of MK-507, Trusopt, for raised intraocular pressure--the Australian experience.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Australia; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1996 |
Central corneal thickness in normal, glaucomatous, and ocular hypertensive eyes.
Topics: Aged; Carbonic Anhydrase Inhibitors; Cornea; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular | 1997 |
Topical 2.0% dorzolamide vs oral acetazolamide for prevention of intraocular pressure rise after neodymium:YAG laser posterior capsulotomy.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cataract Extraction; Double-Blind Method; Female; Follow-Up Studies; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Prospective Studies; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 1997 |
Combination of systemic acetazolamide and topical dorzolamide in reducing intraocular pressure and aqueous humor formation.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular | 1998 |
A multicenter study comparing dorzolamide and pilocarpine as adjunctive therapy to timolol: patient preference and impact on daily life.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Quality of Life; Sulfonamides; Thiophenes; Timolol; Visual Fields | 1998 |
The efficacy and safety of dorzolamide as adjunctive therapy to timolol maleate gellan solution in patients with elevated intraocular pressure. Additivity Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Gels; Humans; Male; Middle Aged; Ocular Hypertension; Solutions; Sulfonamides; Thiophenes; Timolol | 1998 |
A double-masked, randomized, 1-year study comparing the corneal effects of dorzolamide, timolol, and betaxolol. Dorzolamide Corneal Effects Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Cell Count; Double-Blind Method; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1998 |
Clinical efficacy and safety of brinzolamide (Azopt), a new topical carbonic anhydrase inhibitor for primary open-angle glaucoma and ocular hypertension. Brinzolamide Primary Therapy Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 1998 |
Central corneal thickness.
Topics: Carbonic Anhydrase Inhibitors; Cornea; Glaucoma; Humans; Ocular Hypertension; Sulfonamides; Thiophenes | 1998 |
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide. Dorzolamide-Timolol Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components. Dorzolamide-Timolol Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide. Dorzolamide-Timolol Combination Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A comparison of the effectiveness of dorzolamide and acetazolamide in preventing post-operative intraocular pressure rise following phacoemulsification surgery.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Care; Prospective Studies; Sulfonamides; Thiophenes | 1998 |
Additive effect of dorzolamide on aqueous humor flow in patients receiving long-term treatment with timolol.
Topics: Adrenergic beta-Antagonists; Aged; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cohort Studies; Drug Synergism; Female; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 1998 |
Direct costs of glaucoma management following initiation of medical therapy. A simulation model based on an observational study of glaucoma treatment in Germany.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Germany; Glaucoma, Open-Angle; Humans; Insurance, Health, Reimbursement; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 1998 |
Two-year safety study of dorzolamide as monotherapy and with timolol and pilocarpine. Dorzolamide Safety Study Group.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A comparison of the efficacy and tolerability of dorzolamide and acetazolamide as adjunctive therapy to timolol. Oral to Topical CAI Study Group.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
Comparison of the safety and efficacy of the fixed combination of dorzolamide/timolol and the concomitant administration of dorzolamide and timolol: a clinical equivalence study. International Clinical Equivalence Study Group.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
[Postoperative behavior of intraocular pressure after posterior Nd:YAG laser capsulotomy--critical evaluation in preventive administration of local carbonic anhydrase II inhibitor dorzolamide hydrochloride (Trusopt)].
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cataract Extraction; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser Therapy; Male; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Premedication; Sulfonamides; Thiophenes; Treatment Outcome | 1998 |
Additive effect of latanoprost and dorzolamide in patients with elevated intraocular pressure.
Topics: Adult; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Exfoliation Syndrome; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Treatment Outcome | 1998 |
A randomized study of dorzolamide in the prevention of elevated intraocular pressure after anterior segment laser surgery. Dorzolamide Laser Study Group.
Topics: Anterior Eye Segment; Carbonic Anhydrase Inhibitors; Double-Blind Method; Humans; Intraocular Pressure; Laser Therapy; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Sulfonamides; Thiophenes | 1999 |
Comparison of dorzolamide and pilocarpine as adjunctive therapy in patients with open-angle glaucoma and ocular hypertension.
Topics: Adjuvants, Pharmaceutic; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Parasympathomimetics; Patient Dropouts; Pilocarpine; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 1999 |
The dorzolamide/timolol combination versus timolol plus pilocarpine: patient preference and impact on daily life. United States Patient Preference Study Group. International Patient Preference Study Group.
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol | 1999 |
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1999 |
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 1999 |
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1999 |
Effect of dorzolamide and latanoprost on intraocular pressure after small incision cataract surgery.
Topics: Aged; Carbonic Anhydrase Inhibitors; Cataract Extraction; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Minimally Invasive Surgical Procedures; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome | 1999 |
[The ocular hypotensive effect of the combination of latanoprost with dorzolamide].
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 1999 |
Comparison of latanoprost monotherapy to dorzolamide combined with timolol in patients with glaucoma and ocular hypertension.A 3-month randomised study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2000 |
The efficacy and safety of brinzolamide 1% ophthalmic suspension (Azopt) as a primary therapy in patients with open-angle glaucoma or ocular hypertension. Brinzolamide Primary Therapy Study Group.
Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Hypersensitivity; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Safety; Sulfonamides; Suspensions; Thiazines; Thiophenes; Treatment Outcome | 2000 |
Ocular comfort of brinzolamide 1.0% ophthalmic suspension compared with dorzolamide 2.0% ophthalmic solution: results from two multicenter comfort studies. Brinzolamide Comfort Study Group.
Topics: Adult; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Sulfonamides; Suspensions; Thiazines; Thiophenes; Treatment Outcome | 2000 |
Dorzolamide and corneal recovery from edema in patients with glaucoma or ocular hypertension.
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cell Count; Contact Lenses; Cornea; Corneal Edema; Double-Blind Method; Endothelium, Corneal; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Tonometry, Ocular | 2000 |
The use of topical aqueous suppressants in the prevention of postoperative intraocular pressure elevation after pars plana vitrectomy with long-acting gas tamponade.
Topics: Administration, Topical; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Fluorocarbons; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy | 2000 |
Comparison of brimonidine with latanoprost in the adjunctive treatment of glaucoma. ALPHAGAN/XALATAN Study Group.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Ocular Hypertension; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 2000 |
A comparison of latanoprost and dorzolamide in patients with glaucoma and ocular hypertension: a 3 month, randomised study. Ireland Latanoprost Study Group.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antihypertensive Agents; Circadian Rhythm; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 2000 |
Brimonidine 0.2% versus dorzolamide 2% each given three times daily to reduce intraocular pressure.
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 2000 |
Effect of timolol, latanoprost, and dorzolamide on circadian IOP in glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2000 |
Methazolamide 1% in cyclodextrin solution lowers IOP in human ocular hypertension.
Topics: Carbonic Anhydrase Inhibitors; Cyclodextrins; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Methazolamide; Ocular Hypertension; Ophthalmic Solutions; Pharmaceutical Vehicles; Sulfonamides; Thiophenes | 2000 |
Randomised fellow eye comparison of the effectiveness of dorzolamide and apraclonidine on intraocular pressure following phacoemulsification cataract surgery.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Clonidine; Female; Humans; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Prospective Studies; Sulfonamides; Thiophenes | 2000 |
The hypotensive efficacy of dorzolamide HCL-timolol maleate 0.50% vs concomitant use of the two drugs.
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Therapeutic Equivalency; Thiophenes; Timolol | 2000 |
Hypotensive efficacy in primary open-angle glaucoma and ocular hypertension: latanoprost in monotherapy vs timolol and dorzolamide in association.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2000 |
Efficacy of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers in adult patients with glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Down-Regulation; Female; Glaucoma; Humans; Immunologic Factors; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quality of Life; Quinoxalines; Sulfonamides; Thiophenes | 2001 |
Intraindividual comparison of the effects of a fixed dorzolamide-timolol combination and latanoprost on intraocular pressure after small incision cataract surgery.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Middle Aged; Minimally Invasive Surgical Procedures; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2001 |
Comparison of topical brinzolamide 1% and dorzolamide 2% eye drops given twice daily in addition to timolol 0.5% in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 2001 |
Treatment of intraocular pressure elevation after photorefractive keratectomy.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Fluorometholone; Glucocorticoids; Humans; Intraocular Pressure; Lasers, Excimer; Male; Ocular Hypertension; Ophthalmic Solutions; Photorefractive Keratectomy; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2001 |
Comparison of the additive intraocular pressure-lowering effect of latanoprost and dorzolamide when added to timolol in patients with open-angle glaucoma or ocular hypertension: a randomized, open-label, multicenter study in Greece.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Greece; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2001 |
[Clinical evaluation of isopropyl unoprostone (Rescula), in the adjunctive treatment of primary open angle glaucoma].
Topics: Administration, Topical; Antihypertensive Agents; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2001 |
Tolerability and efficacy of dorzolamide versus acetazolamide added to timolol.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 2002 |
Sezolamide: additivity to timolol twice daily.
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 1992 |
Six week safety study of 2% MK-927 administered twice daily to ocular hypertensive volunteers.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Thiophenes; Timolol | 1992 |
Dose response and duration of action of dorzolamide, a topical carbonic anhydrase inhibitor.
Topics: Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Placebos; Sulfonamides; Thiophenes | 1992 |
[Additive effect of timolol and the local carbonic anhydrase inhibitor MK-417 (sezolamide)].
Topics: Aged; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 1991 |
Multiple-dose, dose-response relationship for the topical carbonic anhydrase inhibitor MK-927.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Analysis of Variance; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Placebos; Sulfonamides; Thiophenes | 1991 |
Multiple-dose efficacy comparison of the two topical carbonic anhydrase inhibitors sezolamide and MK-927.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Stereoisomerism; Sulfonamides; Thiophenes | 1991 |
MK-507 versus sezolamide. Comparative efficacy of two topically active carbonic anhydrase inhibitors.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes | 1991 |
MK-927, a topical carbonic anhydrase inhibitor. Dose response and reproducibility.
Topics: Administration, Topical; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Time Factors | 1990 |
[Decrease in intraocular pressure following administration of the local carbonic anhydrase inhibitor (MK-927)--comparison of the effect with pilocarpine].
Topics: Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes | 1990 |
A single dose of the topical carbonic anhydrase inhibitor MK-927 decreases IOP in patients.
Topics: Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes | 1990 |
[Stereospecificity of lowering intraocular pressure using a locally administered carbonic anhydrase inhibitor].
Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Racemases and Epimerases; Sulfonamides; Thiophenes | 1990 |
MK-927: a topical carbonic anhydrase inhibitor. Dose response and duration of action.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Time Factors; Visual Acuity | 1990 |
MK-927: a topically effective carbonic anhydrase inhibitor in patients.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Double-Blind Method; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Placebos; Random Allocation; Sulfonamides; Thiophenes | 1989 |
50 other study(ies) available for thiophenes and Ocular Hypertension
| Article | Year |
|---|---|
Allergic contact dermatitis due to dorzolamide eyedrops.
Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dermatitis, Allergic Contact; Eyelids; Facial Dermatoses; Female; Humans; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes | 2021 |
Eye Drop Dispenser Type and Medication Possession Ratio in Patients With Glaucoma: Single-Use Containers Versus Multiple-Use Bottles.
Topics: Administration, Ophthalmic; Aged; Antihypertensive Agents; Drug Combinations; Drug Packaging; Drug Utilization; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2018 |
Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine.
Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Aged, 80 and over; Brimonidine Tartrate; Conjunctivitis, Allergic; Cyclopentolate; Drug Therapy, Combination; Epithelium, Corneal; Female; Glaucoma, Open-Angle; Granuloma; Humans; Latanoprost; Lubricant Eye Drops; Ocular Hypertension; Ophthalmic Solutions; Prednisolone; Sulfonamides; Thiophenes; Timolol; Uveitis, Anterior | 2018 |
Is the Use of Refrigerated Fixed Combination of Dorzolamide 2%-Timolol 0.5% (COSOPT) Associated with Less Ocular Discomfort: A Pilot Study.
Topics: Antihypertensive Agents; Drug Combinations; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Pilot Projects; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2018 |
Effect of Dorzolamide/Timolol or Brinzolamide/Timolol prophylaxis on intravitreal anti-VEGF injection-induced intraocular hypertension.
Topics: Administration, Topical; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Intravitreal Injections; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Ranibizumab; Retinal Diseases; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Vascular Endothelial Growth Factor A | 2013 |
Urrets- Zavalia Syndrome after glaucoma filtration device implantation.
Topics: Acetazolamide; Aged; Brimonidine Tartrate; Cataract Extraction; Combined Modality Therapy; Drug Resistance; Drug Therapy, Combination; Female; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Hypertension; Miotics; Mydriasis; Ocular Hypertension; Pilocarpine; Prostaglandins F; Quinoxalines; Sulfonamides; Syndrome; Thiophenes; Timolol | 2013 |
[Signs and symptoms of ocular surface disease in patients on topical intraocular pressure-lowering therapy].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blepharitis; Cornea; Cross-Sectional Studies; Female; Fluorescein; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Keratitis; Lacrimal Apparatus Diseases; Male; Microscopy, Acoustic; Middle Aged; Ocular Hypertension; Severity of Illness Index; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Young Adult | 2013 |
Medical management of acute ocular hypertension in a western screech owl (Megascops kennicottii).
Topics: Acute Disease; Animals; Bird Diseases; Carbonic Anhydrase Inhibitors; Diclofenac; Mannitol; Meloxicam; Ocular Hypertension; Strigiformes; Sulfonamides; Thiazines; Thiazoles; Thiophenes | 2014 |
Perioperative dorzolamide-timolol intervention for rising intraocular pressure during steep Trendelenburg positioned surgery.
Topics: Adult; Aged; Anesthesia; Antihypertensive Agents; Blindness; Drug Combinations; Female; Head-Down Tilt; Humans; Laparoscopy; Male; Middle Aged; New England; Ocular Hypertension; Ophthalmic Solutions; Perioperative Care; Postoperative Complications; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2014 |
Dorzolamide-loaded PLGA/vitamin E TPGS nanoparticles for glaucoma therapy: Pharmacoscintigraphy study and evaluation of extended ocular hypotensive effect in rabbits.
Topics: Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Intraocular Pressure; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Ocular Hypertension; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Radionuclide Imaging; Sulfonamides; Thiophenes; Vitamin A; Vitamin E | 2014 |
Anterior and posterior segment changes in rat eyes with chronic steroid administration and their responsiveness to antiglaucoma drugs.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Catalase; Dexamethasone; Disease Models, Animal; Female; Glutathione; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Oxidative Stress; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Rats, Sprague-Dawley; Retina; Sulfonamides; Superoxide Dismutase; Thiophenes; Timolol | 2015 |
Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops.
Topics: Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2015 |
Topics: Acid-Base Imbalance; Acidosis, Renal Tubular; Aged; Air Pollution, Indoor; Amino Acid Substitution; Animals; Animals, Newborn; Anti-Bacterial Agents; Antibodies, Neutralizing; Apoptosis; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Bone Marrow Transplantation; Carbonic Anhydrase Inhibitors; Castleman Disease; Cat Diseases; Cats; Cell Proliferation; Cell- and Tissue-Based Therapy; Chemical and Drug Induced Liver Injury; Chemotaxis, Leukocyte; Clinical Trials as Topic; Coated Materials, Biocompatible; Diagnosis, Differential; Disease Models, Animal; Environmental Monitoring; Female; Gas Chromatography-Mass Spectrometry; Genotype; Granuloma, Foreign-Body; Heart Failure; Hepacivirus; Hepatitis C; Horse Diseases; Horses; Housing; Humans; Hypercalcemia; Hypokalemia; Immunophenotyping; In Vitro Techniques; Liver; Liver Function Tests; Lymphocytes; Macrophages; Male; Medicine, Chinese Traditional; Metabolomics; Mice; Mice, Inbred C57BL; Middle Aged; Models, Animal; Mutation; Myocardial Ischemia; Neovascularization, Physiologic; Neutrophil Infiltration; Ocular Hypertension; Ophthalmic Solutions; Parathyroid Hormone; Particulate Matter; Polyethylene Terephthalates; Prednisolone; Prospective Studies; Prosthesis Design; Prosthesis-Related Infections; Rats; Rats, Wistar; Reactive Oxygen Species; Rifampin; Saponins; Sepsis; Skin; Stem Cells; Stroke Volume; Sulfonamides; Texas; Thiophenes; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Viral Hepatitis Vaccines; Viral Nonstructural Proteins; Viral Proteins; Vitamin D; Wound Healing | 2015 |
Effect of prophylactic topical hypotensive medications in reducing the incidence of postoperative ocular hypertension after phacoemulsification in dogs.
Topics: Administration, Topical; Animals; Dog Diseases; Dogs; Female; Incidence; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Pre-Exposure Prophylaxis; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2017 |
Recurrent serous macular detachment after topical ocular hypotensive medication.
Topics: Administration, Topical; Antihypertensive Agents; Clonidine; Drug Combinations; Drug Therapy, Combination; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Recurrence; Retinal Detachment; Serum; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Visual Acuity | 2008 |
Additive effect of dorzolamide hydrochloride to patients taking travoprost: a retrospective study.
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cloprostenol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Follow-Up Studies; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Retrospective Studies; Sulfonamides; Thiophenes; Travoprost; Treatment Outcome; Visual Fields | 2008 |
Intraocular pressure lowering, change of antiapoptotic molecule expression, and neuroretinal changes by dorzolamide 2%/timolol 0.5% combination in a chronic ocular hypertension rat model.
Topics: Animals; bcl-X Protein; Cell Survival; Disease Models, Animal; Drug Combinations; Glial Fibrillary Acidic Protein; Intraocular Pressure; Male; Ocular Hypertension; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; RNA, Messenger; Sulfonamides; Thiophenes; Timolol | 2008 |
Relationship between visual field severity and response to fixed combination dorzolamide/timolol or timolol alone.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Linear Models; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Severity of Illness Index; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2009 |
Corneal thickness and glaucoma medications.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Cornea; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Relative efficacy of prostaglandins.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Pharmacokinetic-pharmacodynamic and response sensitization modeling of the intraocular pressure-lowering effect of the EP4 Agonist 5-{3-[(2S)-2-{(3R)-3-hydroxy-4-[3-(trifluoromethyl)phenyl]butyl}-5-oxopyrrolidin-1-yl]propyl}thiophene-2-carboxylate (PF-044
Topics: Algorithms; Animals; Aqueous Humor; Ciliary Body; Dogs; Female; Glaucoma; Humans; Intraocular Pressure; Male; Models, Statistical; Ocular Hypertension; Prodrugs; Pyrrolidinones; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes | 2009 |
Simultaneous quantification of carteolol and dorzolamide in rabbit aqueous humor and ciliary body by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry.
Topics: Animals; Antihypertensive Agents; Aqueous Humor; Carteolol; Chromatography, High Pressure Liquid; Ciliary Body; Disease Models, Animal; Humans; Male; Ocular Hypertension; Rabbits; Spectrometry, Mass, Electrospray Ionization; Sulfonamides; Thiophenes | 2010 |
Benzothiophene containing Rho kinase inhibitors: Efficacy in an animal model of glaucoma.
Topics: Animals; Disease Models, Animal; Glaucoma; Haplorhini; HeLa Cells; Humans; Intraocular Pressure; Ocular Hypertension; Protein Kinase Inhibitors; rho-Associated Kinases; Thiophenes | 2010 |
Effectiveness of dorzolamide–timolol (COSOPT) in patients who were treatment naive for open-angle glaucoma or ocular hypertension: the COSOPT first-line study.
Topics: Aged; Drug Combinations; Eye; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2010 |
The clinical impact of 2 different strategies for initiating therapy in patients with ocular hypertension.
Topics: Adult; Antihypertensive Agents; Blindness; Brimonidine Tartrate; Decision Trees; Disease Progression; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Models, Biological; Monte Carlo Method; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Risk Assessment; Sulfonamides; Thiophenes; Timolol | 2011 |
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action.
Topics: Animals; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Disease Models, Animal; Glaucoma; Humans; Models, Molecular; Molecular Structure; Nitric Oxide; Ocular Hypertension; Protein Isoforms; Rabbits; Sulfonamides; Thiophenes | 2011 |
Choroidal detachment induced by dorzolamide 20 years after cataract surgery.
Topics: Aged; Antihypertensive Agents; Cataract Extraction; Choroid Diseases; Drug Therapy, Combination; Female; Humans; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 2002 |
Experience with Cosopt, the fixed combination of timolol and dorzolamide, after switch from free combination of timolol and dorzolamide, in Swiss ophthalmologists' offices.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cluster Analysis; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Ophthalmology; Sulfonamides; Switzerland; Thiophenes; Timolol | 2003 |
Patient persistency with pharmacotherapy in the management of glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Cohort Studies; Drug Utilization; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypertension; Patient Compliance; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes | 2003 |
Switching from systemic to the topical carbonic anhydrase inhibitor dorzolamide: effect on the quality of life of glaucoma patients with drug-related side effects.
Topics: Aged; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Glaucoma, Open-Angle; Health Status Indicators; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quality of Life; Sulfonamides; Thiophenes | 2003 |
Ocular blood flow and systemic blood pressure in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Pulsatile Flow; Regional Blood Flow; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2004 |
A novel neuroprotectant against retinal ganglion cell damage in a glaucoma model and an optic nerve crush model in the rat.
Topics: Animals; Cell Count; Cell Death; Cell Survival; Diethylamines; Disease Models, Animal; Intraocular Pressure; Male; Nerve Crush; Neuroprotective Agents; Ocular Hypertension; Optic Nerve; Optic Nerve Diseases; Rats; Rats, Wistar; Retinal Ganglion Cells; Thiophenes | 2004 |
Bimatoprost versus timolol and dorzolamide.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Lipids; Ocular Hypertension; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2005 |
The effect of combination pharmacotherapy on the prescription trends of glaucoma medications.
Topics: Antihypertensive Agents; Drug Combinations; Drug Prescriptions; Drug Utilization; Glaucoma, Open-Angle; Health Maintenance Organizations; Health Services Research; Health Surveys; Humans; Intraocular Pressure; Israel; Ocular Hypertension; Practice Patterns, Physicians'; Sulfonamides; Thiophenes; Timolol | 2005 |
European Glaucoma Prevention Study.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Europe; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiophenes | 2005 |
Brimonidine/Timolol: a viewpoint by Francisco J. Goñi.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2006 |
pH and drug ionization affects ocular pressure lowering of topical carbonic anhydrase inhibitors.
Topics: Animals; Carbonic Anhydrase Inhibitors; Eye; Hydrogen-Ion Concentration; Imidazoles; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Osmolar Concentration; Rabbits; Solubility; Sulfonamides; Thiophenes | 1993 |
Ocular absorption, blood levels, and excretion of dorzolamide, a topically active carbonic anhydrase inhibitor.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Erythrocytes; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes | 1997 |
Influence of dorzolamide on corneal thickness, endothelial cell count and corneal sensibility.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Cell Count; Chronic Disease; Cornea; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Sensation; Sulfonamides; Thiophenes; Timolol | 1998 |
[Is corneal thickness measurement reliable and useful?].
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antihypertensive Agents; Cornea; Corneal Transplantation; Diabetes Mellitus; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Observer Variation; Ocular Hypertension; Reproducibility of Results; Sulfonamides; Thiophenes; Ultrasonography | 1999 |
Sterile mucopurulent conjunctivitis associated with the use of dorzolamide eyedrops.
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Conjunctiva; Conjunctivitis; Female; Glaucoma, Angle-Closure; Humans; Male; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1999 |
Comparison of the efficacy and safety of latanoprost 0.005% compared to brimonidine 0.2% or dorzolamide 2% when added to a topical beta-adrenergic blocker in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Safety; Sulfonamides; Thiophenes; Tonometry, Ocular | 2000 |
[Central corneal thickness in normal eyes, patients with ocular hypertension, normal-pressure and open-angle glaucomas--a clinical study].
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Case-Control Studies; Cornea; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Reference Values; Sex Distribution; Sulfonamides; Thiophenes | 2000 |
Refractive change after dorzolamide use in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Refractive Errors; Sulfonamides; Thiophenes | 2001 |
4-substituted thiophene- and furan-2-sulfonamides as topical carbonic anhydrase inhibitors.
Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cells, Cultured; Disease Models, Animal; Erythrocytes; Furans; Glutathione; Guinea Pigs; Humans; Ocular Hypertension; Rabbits; Structure-Activity Relationship; Sulfonamides; Thiophenes | 1992 |
Topically active carbonic anhydrase inhibitors. 4. [(Hydroxyalkyl)sulfonyl]benzene and [(hydroxyalkyl)sulfonyl]thiophenesulfonamides.
Topics: Administration, Topical; Animals; Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Chymotrypsin; Glutathione; Intraocular Pressure; Ocular Hypertension; Rabbits; Structure-Activity Relationship; Sulfonamides; Thiophenes | 1991 |
A comparison of L-671,152 and MK-927, two topically effective ocular hypotensive carbonic anhydrase inhibitors, in experimental animals.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chymotrypsin; Ciliary Body; Erythrocytes; Female; In Vitro Techniques; Iris; Light Coagulation; Macaca fascicularis; Male; Ocular Hypertension; Ocular Hypotension; Rabbits; Sulfonamides; Thiophenes; Trabeculectomy | 1990 |
MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chymotrypsin; Ciliary Body; Dose-Response Relationship, Drug; Female; Intraocular Pressure; Iris; Kinetics; Macaca fascicularis; Male; Ocular Hypertension; Rabbits; Sulfonamides; Thiophenes | 1990 |
Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity.
Topics: Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Glaucoma; Guinea Pigs; Intraocular Pressure; Ocular Hypertension; Rabbits; Skin; Sulfonamides; Thiophenes | 1989 |
Topical carbonic anhydrase inhibitors.
Topics: Administration, Topical; Benzothiazoles; Carbonic Anhydrase Inhibitors; Ethoxzolamide; Gels; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiazoles; Thiophenes | 1989 |