thiophenes has been researched along with Neoplasms in 214 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (5.14) | 18.7374 |
| 1990's | 28 (13.08) | 18.2507 |
| 2000's | 46 (21.50) | 29.6817 |
| 2010's | 106 (49.53) | 24.3611 |
| 2020's | 23 (10.75) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, CH; Chang, HH; Chang, PW; Chen, CH; Chen, CW; Chen, PH; Hsiao, WC; Hsieh, SH; Hsueh, CC; Huang, CH; Hung, MS; Kuo, CC; Kuppusamy, R; Li, AS; Liao, FY; Lin, CY; Lin, LM; Peng, YH; Shih, C; Song, JS; Tien, YW; Ueng, SH; Wu, MH; Wu, SY; Yao, JY; Yeh, TK; Yu, JC | 1 |
| Afonso, J; Antunes, B; Baltazar, F; Batista, A; Pinto-Ribeiro, F; Silva, A | 1 |
| Ding, X; Wang, H; Wang, Y; Wu, A; Yang, F; Zheng, Z | 1 |
| Ding, C; Geng, M; Li, X; Liu, Z; Ma, J; Shen, A; Song, Z; Wang, X; Xiao, R; Xie, Z; Zhang, A; Zhang, Y | 1 |
| Huan, S; Li, Z; Liao, S; Liu, S; Song, G; Wang, Y; Yin, X; Zhang, XB; Zhang, Y | 1 |
| Huang, R; Lan, M; Li, B; Pang, E; Song, X; Tan, Q; Tan, S; Wang, B; Yang, K; Zhao, S | 1 |
| Bacon, CM; Banerji, U; Chénard-Poirier, M; Dragoni, I; Greystoke, A; Halford, S; Heinzmann, K; Howell, EC; Innes, WA; Keun, HC; Morris, K; Payne, GS; Petrides, G; Plummer, C; Plummer, R; Potter, S; Rata, M; Salisbury, BM; Sloan, P; Veal, GJ; Wedge, SR | 1 |
| Fang, L; Feng, S; Hou, Y; Huang, K; Ma, P; Meng, Q; Su, R; Xing, F; Yang, H; Zhang, Y | 1 |
| Naing, A | 1 |
| Aydın, M | 1 |
| Cong, H; Gu, C; Miao, Y; Shen, Y; Yu, B; Zhu, Y | 1 |
| Gilmore, A; King, L | 1 |
| He, S; Jiang, Y; Li, J; Pu, K | 1 |
| Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; Lv, YQ; Lyu, HD; Lyu, J; Ma, C; Ma, G; Ma, L; Ma, Q; Ma, X; Ma, Y; Macha, SJ; MacLean, E; Mahalapbutr, P; Maina, T; Malfait, F; Malfertheiner, MV; Malzert-Fréon, A; Mansouri, E; Mao, C; Marcellin, E; Marchiori, PER; Marcotte, DJ; Maréchal, A; Maric, N; Maris, JM; Maron, L; Marti, CN; Martínez-Milla, J; Mateo, J; Mather, K; Mathison, CJN; Matthay, MA; Maxwell, CL; Mazier, D; Mazumder, D; Mazurkiewicz, M; Mazzucchelli, TG; McAuley, DF; Mccoy, K; McVicar, DW; Mebel, AM; Mech, A; Meester, EJ; Meiselbach, H; Melero, I; Ménard, G; Meng, X; Mengya, Y; Merle, G; Meunier, B; Mfarrej, B; Mi, K; Migueliz, I; Mikuška, P; Miladi, K; Miletich, R; Millar, JE; Mills, MR; Milne, R; Minute, L; Misiak, M; Mo, F; Modi, A; Mok, F; Molina, C; Mollen, CJ; Molteni, V; Montalto, M; Montet, D; Monti, MC; Moor, MB; Moravec, P; Morsiani, C; Murillo, E; Murugan, P; Muslem, R; Myers, RK; N'guessan, FK; Nabil, H; Nadal, J; Nadeem, M; Nafady, MM; Nafie, MS; Nair, HP; Nakano, R; Nance, J; Naren, N; Neil, CJ; Nelson, J; Nery, FC; Netsch, C; Nguyen, TH; Ni, L; Ni, YX; Nie, W; Nielsen, LK; Nigam, K; Nikolayev, AA; Nishiyama, M; Niu, LL; Niu, PP; Nock, BA; Noer, PR; Noll, G; Noll, S; Norenberg, JP; Nowicka, J; Nutho, B; O'Connor, M; Obonyo, NG; Ochiai, T; Ochoa, MC; Oh, BL; Oh, S; Olczak, J; Olivares, X; Ommurugan, B; Oosthuizen, MC; Operario, D; Orešič, M; Oshima, K; Otano, I; Ou, Y; Owen, TW; Oxvig, C; Pacey, V; Pai, M; Paik, H; Paiva, R; Palmieri, EM; Palpant, N; Pan, L; Pan, Q; Panahi, S; Pang, B; Pang, ZC; Pannecouque, C; Paris, L; Park, D; Park, DJ; Park, E; Park, EC; Park, IH; Park, JH; Park, JI; Park, S; Passmore, MR; Pattaranggoon, NC; Paun, M; Pedersen, S; Pedron, J; Peng, M; Peng, X; Penzhorn, BL; Pérez-Camargo, D; Perez-Maldonado, R; Pérez-Vicente, C; Pham, TD; Pickering, L; Pickersgill, NA; Pinault, E; Pinotsis, N; Plan, M; Pocino, K; Poh, CL; Pons, EDC; Popoff, MR; Porri, D; Pourmand, A; Pratviel, G; Prudente, DO; Qi, H; Qi, N; Qian, LY; Qiao, L; Qiao, Q; Qin, QP; Qiu, N; Qiu, SW; Qu, F; Quan, M; Quigg, A; Raee, E; Raibaud, P; Ramanitrahasimbola, D; Rapoport, L; Rasby, RJ; Rasoanirina, BNV; Raspini, B; Ratner, JR; Razafindrakoto, Z; Redd, MA; Ren, H; Ren, N; Rey, J; Reynolds, CP; Rich, PR; Richards, CJ; Rigol, M; Rimoldi, S; Robert, P; Rodrigues, AE; Roe, JH; Rohde, S; Rokita, JL; Roland, J; Rombaut, L; Ronkainen, J; Rothenberg, SM; Roy, SC; Ruan, Z; Rucker, PV; Rueda, D; Ruhwald, M; Rungrotmongkol, T; Rupert, AS; Rusjan, P; Ryabov, AD; Rysä, J; Saad, NES; Sabioni, P; Sadow, PM; Sahai, N; Salem, HF; Salinas, B; Salonurmi, T; Samé Guerra, D; Sánchez, J; Sanchez-González, J; Sanmamed, MF; Sansores-Peraza, P; Santoro, JC; Santschi, PH; Saritas, T; Sarkisova, Y; Savolainen, MJ; Scherberich, JE; Schlom, DG; Schmelz, EM; Schmid, MC; Schneider, MP; Schumacher, S; Schwartz, JC; Schwartzer, JJ; Schwehr, K; Schweitzer, DH; Scott, ME; Sedky, NK; See Hoe, L; Sejian, V; Selvaraju, S; Sen, SK; Seo, G; Šerý, O; Settles, JA; Sfar, S; Shaffer, J; Shan, GL; Shang, Q; Shannahan, JH; Shao, B; Shao, H; Shao, J; Shao, ZH; Shasha, Y; Shaw, K; Sheeba, V; Shekar, K; Shen, G; Shen, H; Shen, XD; Shen, Y; Sherrell, PC; Shete, PB; Shi, AX; Shi, J; Shi, JH; Shi, S; Shi, X; Shigeta, Y; Shimbo, A; Shin, E; Sikka, N; Silhavy, TJ; Simanon, N; Simard, S; Simon, J; Simon, M; Simpson, SD; Simundic, AM; Since, M; Singh, B; Singhroy, DN; Sinisterra, OT; Smith, EH; Sobreira, TJP; Solanes, N; Somasundar, Y; Sommerer, C; Sonei, A; Song, B; Song, E; Song, J; Song, M; Song, Y; Soo Lee, M; Sorensen, MD; Sournia-Saquet, A; Spaepen, E; Spirk, D; Srivastava, S; Stancill, JS; Stanczak, PS; Starenki, D; Starr, F; Step, DL; Steubl, D; Stigliani, JL; Stráská, J; Sträter, N; Su, ZZ; Sudano, I; Suen, JY; Suh, HJ; Sui, ZY; Suico, JG; Suleiman, K; Sumon, K; Sun, HB; Sun, J; Sun, L; Sun, LL; Sun, M; Sun, Q; Sun, W; Sun, X; Sun, XF; Sun, Y; Sun, YB; Sun, YH; Sun, YN; Sun, Z; Sunada, K; Suzuki, S; Sylvan, JB; Takala, J; Talla, D; Tamir, Z; Tan, SJ; Tanda, S; Tang, H; Tang, J; Tang, LF; Tang, SJ; Tang, Y; Tao, FB; Tappel, R; Taratkin, M; Teijeira, Á; Tellew, JE; Thomas, AM; Thomas, SG; Thomson, SR; Tian, J; Tie, Y; Tirado, JL; Tolonen, A; Tosato, G; Tronnet, A; Tsai, S; Turtoi, A; Turtoi, E; Tvrdoňová, M; Tyagi, A; Tzou, DT; Uddin Ahmad, Z; Urias, E; Usawachintachit, M; Ustriyana, P; Utsumi, F; Vacca, M; Vaculovič, T; Vaidya, SS; Valentin, A; Valgepea, K; van den Berg, P; van den Bergh, JP; van der Heiden, K; van Gaalen, K; Van Gemert, W; van Haard, PMM; van Hest, JCM; Vecchiarelli, E; Večeřa, Z; Venkatesh, R; Verhaeghe, P; Verhagen, HJ; Vetter, JM; Vieira, D; Vilchez-Tschischke, JP; Villena-Gutierrez, R; Villoslada Terrones, V; Vital-Jacome, M; Voelkl, J; Vogel, K; Vogrin, S; Volke, D; von Bahr, V; Vysloužil, J; Wade, TL; Wagner-Gillespie, M; Walsh, SW; Wan, LJ; Wan, SP; Wang, AL; Wang, B; Wang, BY; Wang, C; Wang, D; Wang, F; Wang, H; Wang, HR; Wang, HY; Wang, J; Wang, JY; Wang, K; Wang, L; Wang, LF; Wang, P; Wang, Q; Wang, R; Wang, SF; Wang, SP; Wang, SR; Wang, T; Wang, W; Wang, WP; Wang, X; Wang, XJ; Wang, Y; Wang, YL; Wang, YN; Wáng, YXJ; Wang, Z; Wang, ZF; Wang, ZY; Waning, B; Warner, JM; Washington, SL; Watson, AK; Wei, B; Wei, C; Wei, F; Wei, X; Wei, Y; Wemhoff, AP; Wen, Z; Weng, TT; Wesdemiotis, C; Wheeler, DA; Wildner, M; Wilson, BK; Wirth, LJ; Wissler, M; Wu, F; Wu, G; Wu, J; Wu, KH; Wu, MC; Wu, P; Wu, PK; Wu, S; Wu, W; Wu, X; Wu, XP; Wu, Y; Wyatt, E; Wyllie, S; Xia, Y; Xiao, BH; Xiao, SZ; Xiao, W; Xiao, X; Xiao, Z; Xie, D; Xie, K; Xie, X; Xie, Y; Xie, YF; Xin, S; Xin, Z; Xing, Q; Xing, WQ; Xiong, D; Xiong, X; Xu, C; Xu, D; Xu, F; Xu, G; Xu, H; Xu, J; Xu, JY; Xu, L; Xu, N; Xu, W; Xu, X; Xu, Y; Xu, YM; Xue, H; Xue, J; Xue, Z; Yan, R; Yan, SQ; Yan, W; Yan, X; Yan, Z; Yang, C; Yang, D; Yang, F; Yang, FC; Yang, G; Yang, J; Yang, M; Yang, P; Yang, Q; Yang, R; Yang, S; Yang, SJ; Yang, TWW; Yang, X; Yang, Y; Yang, Z; Yao, C; Yao, L; Yao, LP; Yao, M; Yao, T; Yao, W; Yao, Y; Yaseen, T; Yazdani, V; Ye, J; Ye, S; Yerys, BE; Yi, HWL; Yi, JL; Yin, F; Yin, J; Yin, Y; Yin, Z; Yong, ZP; Yongli, S; Yoo, JS; Yoshikawa, N; You, Q; Yu, B; Yu, CQ; Yu, H; Yu, HG; Yu, J; Yu, L; Yu, Q; Yu, X; Yu, Y; Yu, YK; Yu, Z; Yuan, Q; Yuan, R; Yuan, W; Yuan, X; Yuan, Y; Zager, RA; Zagozdzon, A; Zaller, N; Zang, YP; Zappi, ME; Zelikoff, JT; Zeman, T; Zhai, X; Zhan, P; Zhang, B; Zhang, C; Zhang, G; Zhang, H; Zhang, HB; Zhang, J; Zhang, JS; Zhang, L; Zhang, M; Zhang, Q; Zhang, RX; Zhang, S; Zhang, T; Zhang, W; Zhang, WH; Zhang, X; Zhang, XX; Zhang, Y; Zhang, YQ; Zhang, YW; Zhang, Z; Zhang, ZH; Zhao, D; Zhao, FL; Zhao, K; Zhao, L; Zhao, M; Zhao, R; Zhao, S; Zhao, W; Zhao, WG; Zhao, X; Zhao, Y; Zheng, G; Zheng, J; Zheng, S; Zheng, W; Zheng, Y; Zheng, YG; Zhong, Z; Zhou, C; Zhou, D; Zhou, H; Zhou, HY; Zhou, L; Zhou, Q; Zhou, X; Zhou, Y; Zhou, YL; Zhou, Z; Zhu, J; Zhu, L; Zhu, N; Zhu, X; Zhu, XF; Zhu, Y; Zhu, Z | 1 |
| Azizov, S; Elmasry, MR; Lee, CH; Lee, YI; Sharipov, M; Tawfik, SM | 1 |
| Juvale, K; Puri, S | 1 |
| Kumar, N; Mishra, I; Mishra, R; Sachan, N | 1 |
| Chen, Z; Guo, T; Hu, L; Liu, R; Liu, Y; Su, X; Tian, B; Wang, C; Ying, L | 1 |
| Chen, H; Liu, Y; Men, X; Sun, C; Wang, R; Wu, C; Yuan, Z; Zhang, X | 1 |
| Jang, HR; Kim, CH; Shin, SB; Yim, H | 1 |
| Auti, PB; Bhilare, NV; Marulkar, VS; Pise, VJ | 1 |
| Chen, Z; Guo, T; Hu, L; Liu, R; Liu, Y; Tian, B; Wang, C; Ying, L | 1 |
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| Brock, K; Evans, TR; Gedrich, R; Hopkins, CA; Macpherson, IR; Poondru, S; Simon, GR; Stephens, A; Stewart, K | 1 |
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| BHAVSAR, MD; NARURKAR, MV; NERURKAR, MK; SAHASRABUDHE, MB; TILAK, BD | 1 |
| KOTNIS, LB; NARURKAR, MV; SAHASRABUDHE, MB | 1 |
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| Baumgartner, KJ; Bodreddigari, S; Curphey, TJ; Gange, SJ; Kensler, TW; Li, Y; Roebuck, BD; Sutter, TR; Yan, J | 1 |
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| Bukowski, R; Chiappori, AA; Creaven, PJ; Eckhardt, SG; Ikeda, M; Javle, MM; Kambayashi, Y; Mekhail, T; O'bryant, CL; Sullivan, DM; Tanaka, K; Yamada-Sawada, T; Yano, Y | 1 |
| Berg, R; Koropatnick, J; Pandyra, AA; Vincent, M | 1 |
| Fishbein, JC; McCraken, J; Muthukumaran, RB; Sostaric, JZ; Velayutham, M; Zweier, JL | 1 |
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| Drengler, R; Eckardt, J; Eckhardt, G; Villalona-Calero, M; Von Hoff, D | 1 |
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53 review(s) available for thiophenes and Neoplasms
| Article | Year |
|---|---|
In Vivo Anticancer Activity of AZD3965: A Systematic Review.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Management; Disease Progression; Drug Evaluation, Preclinical; Energy Metabolism; Glycolysis; Humans; Lactic Acid; Monocarboxylic Acid Transporters; Neoplasms; Pyrimidinones; Signal Transduction; Symporters; Thiophenes; Tumor Microenvironment; Warburg Effect, Oncologic; Xenograft Model Antitumor Assays | 2021 |
Emerging approaches to target mitochondrial apoptosis in cancer cells.
Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bridged Bicyclo Compounds, Heterocyclic; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Sulfonamides; Thiophenes | 2019 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Monocarboxylate transporter 1 and 4 inhibitors as potential therapeutics for treating solid tumours: A review with structure-activity relationship insights.
Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Humans; Monocarboxylic Acid Transporters; Muscle Proteins; Neoplasms; Pyrimidinones; Structure-Activity Relationship; Symporters; Thiophenes; Uracil | 2020 |
A Review on Anticancer Activities of Thiophene and Its Analogs.
Topics: Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Neoplasms; Pyrimidines; Structure-Activity Relationship; Thiophenes | 2020 |
Diverse Thiophenes as Scaffolds in Anti-cancer Drug Development: A Concise Review.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase IX; Cell Survival; DNA Damage; HSP90 Heat-Shock Proteins; Humans; Microtubules; Neoplasms; Structure-Activity Relationship; Thiophenes | 2021 |
Unearthing the Janus-face cholesterogenesis pathways in cancer.
Topics: Animals; Anticholesteremic Agents; Antineoplastic Agents; Benzylamines; Cholesterol; Humans; Lanosterol; Neoplasms; Terbinafine; Thiophenes | 2022 |
Fluoropyrimidine-induced cardiotoxicity.
Topics: Acetates; Capecitabine; Cardiotoxicity; Cardiovascular Diseases; Drug Combinations; Fluorouracil; Humans; Neoplasms; Pyrimidines; Pyrrolidines; Quinazolines; Thiophenes; Thymine; Trifluridine; Uracil; Uridine | 2018 |
Targeting Mcl-1 and other Bcl-2 family member proteins in cancer therapy.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; Drug Combinations; Drug Therapy, Combination; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms; Protein Isoforms; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Sulfonamides; Thiophenes | 2019 |
T-LAK cell-originated protein kinase (TOPK): an emerging target for cancer-specific therapeutics.
Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Disease Models, Animal; Drug Discovery; Humans; Indolizines; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Targeted Therapy; Neoplasms; Quinolones; Quinoxalines; Thiophenes; Treatment Outcome | 2018 |
Use of raltitrexed as an alternative to 5-fluorouracil and capecitabine in cancer patients with cardiac history.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Heart Diseases; Humans; Neoplasms; Quinazolines; Retrospective Studies; Thiophenes | 2013 |
Current clinical trials with polo-like kinase 1 inhibitors in solid tumors.
Topics: Animals; Antineoplastic Agents; Cell Cycle Proteins; Clinical Trials as Topic; Humans; Molecular Targeted Therapy; Neoplasms; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Thiophenes | 2013 |
New anticoagulants in the treatment of patients with cancer-associated venous thromboembolism.
Topics: Administration, Oral; Anticoagulants; Benzimidazoles; beta-Alanine; Dabigatran; Drug Administration Schedule; Heparin, Low-Molecular-Weight; Humans; Morpholines; Neoplasms; Pyrazoles; Pyridones; Randomized Controlled Trials as Topic; Rivaroxaban; Thiophenes; Treatment Outcome; Venous Thromboembolism; Warfarin | 2013 |
Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline.
Topics: Adult; Amines; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Baclofen; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Gels; Humans; Incidence; Ketamine; Neoplasms; Neuralgia; Peripheral Nervous System Diseases; Quality of Life; Randomized Controlled Trials as Topic; Severity of Illness Index; Survivors; Thiophenes; Treatment Outcome; United States | 2014 |
Meta-analysis of the efficacy and safety of new oral anticoagulants in patients with cancer-associated acute venous thromboembolism.
Topics: Acute Disease; Administration, Oral; Anticoagulants; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Morpholines; Neoplasms; Randomized Controlled Trials as Topic; Recurrence; Risk; Rivaroxaban; Thiophenes; Treatment Outcome; Venous Thrombosis | 2014 |
Direct oral anticoagulants in the management of venous thromboembolism--evidence from major clinical trials.
Topics: Administration, Oral; Anticoagulants; Benzimidazoles; beta-Alanine; Clinical Trials as Topic; Dabigatran; Humans; Morpholines; Neoplasms; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Thiophenes; Venous Thromboembolism | 2014 |
Current use of drugs affecting the central nervous system for chemotherapy-induced peripheral neuropathy in cancer patients: a systematic review.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Antineoplastic Agents; Boronic Acids; Bortezomib; Carbamazepine; Central Nervous System; Cyclohexanols; Duloxetine Hydrochloride; Epothilones; Humans; Neoplasms; Neuralgia; Oxcarbazepine; Peripheral Nervous System Diseases; Pyrazines; Taxoids; Thalidomide; Thiophenes; Venlafaxine Hydrochloride; Vinca Alkaloids | 2015 |
Screening methods for AMP-activated protein kinase modulators: a patent review.
Topics: AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Drug Design; Homeostasis; Humans; Metabolic Diseases; Molecular Targeted Therapy; Neoplasms; Patents as Topic; Pyrones; Thiophenes | 2015 |
Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases.
Topics: Aldehydes; Animals; Apoptosis; Cell Survival; Coumarins; Disease Models, Animal; Disease Progression; DNA-Binding Proteins; Drug Design; Drug Discovery; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Endoribonucleases; Homeostasis; Humans; Mice; Neoplasms; Neurodegenerative Diseases; Prognosis; Protein Folding; Protein Serine-Threonine Kinases; Quercetin; Regulatory Factor X Transcription Factors; Signal Transduction; Sulfonamides; Thiophenes; Toyocamycin; Transcription Factors; Unfolded Protein Response; X-Box Binding Protein 1 | 2015 |
Dithiolethiones for cancer chemoprevention: where do we stand?
Topics: Animals; Anticarcinogenic Agents; Chemoprevention; Humans; Models, Biological; Neoplasms; Pyrazines; Thiones; Thiophenes | 2008 |
C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation.
Topics: Animals; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Pharmacogenetics; Polymorphism, Genetic; Quinazolines; Thiophenes; Treatment Outcome | 2009 |
New antithrombotic drugs: potential for use in oncology.
Topics: Administration, Oral; Anticoagulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Factor Xa; Factor Xa Inhibitors; Female; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Injections, Subcutaneous; Male; Morpholines; Neoplasms; Prognosis; Pyrazoles; Pyridones; Rivaroxaban; Severity of Illness Index; Survival Analysis; Thiophenes; Treatment Outcome; Venous Thromboembolism | 2009 |
VTE prophylaxis for the medical patient: where do we stand? - a focus on cancer patients.
Topics: Anticoagulants; Aspirin; Fondaparinux; Heparin; Heparin, Low-Molecular-Weight; Humans; Morpholines; Neoplasms; Polysaccharides; Pyrazoles; Pyridones; Rivaroxaban; Thiophenes; Venous Thromboembolism; Warfarin | 2010 |
Potential of new anticoagulants in patients with cancer.
Topics: Anticoagulants; Benzimidazoles; Biotin; Clinical Trials as Topic; Dabigatran; Humans; Morpholines; Neoplasms; Oligosaccharides; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiophenes; Thrombosis | 2010 |
Prasugrel as a potential cancer promoter: review of the unpublished data.
Topics: Acute Coronary Syndrome; Humans; Incidence; Neoplasms; Periodicals as Topic; Piperazines; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Risk Factors; Thiophenes; United States | 2010 |
Preventing postsurgical venous thromboembolism: pharmacological approaches.
Topics: Aged; Anticoagulants; Antithrombins; Arthroscopy; Bariatric Surgery; Benzimidazoles; Blood Coagulation Disorders, Inherited; Dabigatran; Fondaparinux; Heparin; Heparin, Low-Molecular-Weight; Hip Fractures; Humans; Kidney; Knee; Laparoscopy; Morpholines; Neoplasms; Orthopedic Procedures; Polysaccharides; Postoperative Complications; Pyridines; Rivaroxaban; Thiophenes; Thrombophilia; Venous Thromboembolism | 2011 |
Polo-like kinases inhibitors.
Topics: Binding, Competitive; Catalytic Domain; Cell Cycle Proteins; DNA Repair; Humans; Neoplasms; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Pyridines; Quinazolines; Thiophenes | 2012 |
Preclinical models in electrochemotherapy: the role of veterinary patients.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Cat Diseases; Cats; Cisplatin; Dog Diseases; Dogs; Drug Evaluation, Preclinical; Electrochemotherapy; Epirubicin; Head and Neck Neoplasms; Melanoma; Mitoxantrone; Neoplasms; Quinazolines; Sarcoma; Thiophenes | 2012 |
The glutathione system in alkylator resistance.
Topics: Alkylating Agents; Anticarcinogenic Agents; Buthionine Sulfoximine; Enzyme Inhibitors; Ethacrynic Acid; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Humans; Neoplasms; Pyrazines; Thiones; Thiophenes | 2002 |
[Angiogenesis research--quo vadis?].
Topics: Adult; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Apoptosis; Bevacizumab; Cell Communication; Drug Evaluation, Preclinical; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Ephrins; Forecasting; Growth Substances; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Lymphokines; Metalloendopeptidases; Mice; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Phenylalanine; Randomized Controlled Trials as Topic; Receptors, Vascular Endothelial Growth Factor; Research; Signal Transduction; Thalidomide; Thiophenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Current therapies for xerostomia and salivary gland hypofunction associated with cancer therapies.
Topics: Acupuncture Therapy; Antineoplastic Agents; Chewing Gum; Diet; Flavoring Agents; Humans; Muscarinic Agonists; Neoplasms; Oral Hygiene; Palliative Care; Parasympathomimetics; Pilocarpine; Quinuclidines; Radiotherapy; Saliva; Salivary Glands; Thiophenes; Xerostomia | 2003 |
Dietary aflatoxin exposure and chemoprevention of cancer: a clinical review.
Topics: Aflatoxins; Animals; Anticarcinogenic Agents; Biomarkers; Chlorophyllides; Diet; Humans; Neoplasms; Pyrazines; Reverse Transcriptase Inhibitors; Thiones; Thiophenes | 2003 |
Thymidylate synthase inhibitors as anticancer agents: from bench to bedside.
Topics: Antineoplastic Agents; Enzyme Inhibitors; Humans; Indoles; Isoindoles; Neoplasms; Quinazolines; Randomized Controlled Trials as Topic; Thiophenes; Thymidylate Synthase | 2003 |
Arzoxifene Eli Lilly.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drugs, Investigational; Humans; Neoplasms; Piperidines; Technology, Pharmaceutical; Thiophenes | 2003 |
1,3-Propane sultone, an extremely potent experimental carcinogen: what should be expected in humans?
Topics: Brain Neoplasms; Carcinogens; Glioma; Humans; Male; Neoplasms; Occupational Exposure; Thiophenes | 2004 |
[Expression of matrix metalloproteinases in patients with malignant tumors].
Topics: Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Clinical Trials as Topic; Diphosphonates; Disease Progression; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Hydroxamic Acids; Imidazoles; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasms; Organic Chemicals; Phenylalanine; Phenylbutyrates; Prognosis; Protease Inhibitors; Thiophenes; Time Factors; Tissue Inhibitor of Metalloproteinases | 2004 |
Carcinogen-DNA and protein adducts as intermediate biomarkers for human chemoprotection trials.
Topics: Aflatoxins; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; DNA; Humans; Liver Neoplasms, Experimental; Neoplasms; Proteins; Pyrazines; Thiones; Thiophenes | 1994 |
Cancer chemoprotection by oltipraz: experimental and clinical considerations.
Topics: Animals; Anticarcinogenic Agents; Clinical Trials as Topic; Drug Screening Assays, Antitumor; Female; Humans; Male; Neoplasms; Neoplasms, Experimental; Pyrazines; Thiones; Thiophenes | 1993 |
New anticancer agents in clinical development.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Deoxycytidine; Enzyme Inhibitors; Fluorouracil; Gemcitabine; Humans; Neoplasms; Polysaccharides, Bacterial; Prodrugs; Quinazolines; Tegafur; Thiophenes; Thymidylate Synthase; Uracil | 1995 |
The development of new chemotherapeutic agents.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Deoxycytidine; Gemcitabine; Glutamates; Guanine; Humans; Irinotecan; Neoplasms; Pemetrexed; Quinazolines; Thiophenes; Trimetrexate | 1996 |
New antifolates in clinical development.
Topics: Aminopterin; Antimetabolites, Antineoplastic; Antineoplastic Agents; Drugs, Investigational; Folic Acid Antagonists; Humans; Neoplasms; Pyrimidines; Quinazolines; Thiophenes; Trimetrexate | 1995 |
[Development of anti tumor agents targeting angiogenesis].
Topics: Antineoplastic Agents; Clinical Trials as Topic; Cyclohexanes; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Hydroxamic Acids; Interferon-alpha; Interleukin-12; Neoplasms; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Phenylalanine; Platelet Factor 4; Polysaccharides, Bacterial; Sesquiterpenes; Thalidomide; Thiophenes; Triazines; Triazoles; Tumor Cells, Cultured | 1997 |
Experimental and clinical studies on the use of matrix metalloproteinase inhibitors for the treatment of cancer.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Ascites; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Extracellular Matrix; Female; Humans; Male; Metalloendopeptidases; Mice; Middle Aged; Neoplasms; Phenylalanine; Pleural Effusion, Malignant; Protease Inhibitors; Rats; Thiophenes | 1996 |
Matrix metalloproteinase inhibitors.
Topics: Antineoplastic Agents; Cell Division; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Down-Regulation; Drugs, Investigational; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Hydroxamic Acids; Metalloendopeptidases; Molecular Weight; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Phenylalanine; Protease Inhibitors; Protein Kinase C; Proteins; Thiophenes; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinase-3; Tissue Inhibitor of Metalloproteinases | 1997 |
Matrix metalloproteinase inhibitors: present achievements and future prospects.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Enzyme Inhibitors; Extracellular Matrix; Humans; Hydroxamic Acids; Metalloendopeptidases; Neoplasm Metastasis; Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes | 1997 |
Tumor resistance to antimetabolites.
Topics: Antimetabolites, Antineoplastic; Cell Cycle Proteins; Deoxycytidine; DNA Damage; DNA, Neoplasm; Drug Resistance, Neoplasm; Fluorouracil; Gemcitabine; Gene Amplification; Humans; Methotrexate; Mutation; Neoplasms; Quinazolines; Thiophenes | 1998 |
Glutathione S-transferases--biomarkers of cancer risk and chemopreventive response.
Topics: Animals; Anticarcinogenic Agents; Biomarkers; Brassica; Colitis, Ulcerative; Colorectal Neoplasms; Disease Models, Animal; Enzyme Induction; Gene Expression; Glutathione Transferase; Humans; Inactivation, Metabolic; Mice; Neoplasms; Pyrazines; Risk Factors; Thiones; Thiophenes | 1998 |
[Neovascularization and tumor development].
Topics: Angiostatins; Antibiotics, Antineoplastic; Antineoplastic Agents; Collagen; Cyclohexanes; Endostatins; Humans; Hydroxamic Acids; Interferons; Interleukin-12; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Peptide Fragments; Phenylalanine; Plasminogen; Sesquiterpenes; Thalidomide; Thiophenes | 1998 |
Development of cancer chemopreventive agents: oltipraz as a paradigm.
Topics: Animals; Anticarcinogenic Agents; Chemoprevention; Cytochrome P-450 Enzyme System; Drug Approval; Enzyme Induction; Humans; Neoplasms; Pyrazines; Thiones; Thiophenes | 1999 |
Development of matrix metalloproteinase inhibitors in cancer therapy.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Biphenyl Compounds; Clinical Trials as Topic; Drugs, Investigational; Enzyme Inhibitors; Humans; Hydroxamic Acids; Imidazoles; Matrix Metalloproteinase Inhibitors; Neoplasms; Organic Chemicals; Phenylalanine; Phenylbutyrates; Protease Inhibitors; Pyrazines; Sulfonamides; Tetracycline; Tetracyclines; Thiophenes | 2001 |
Clinical and preclinical pharmacokinetics of raltitrexed.
Topics: Adult; Animals; Antimetabolites, Antineoplastic; Area Under Curve; Child; Clinical Trials as Topic; Drug Interactions; Enzyme Inhibitors; Half-Life; Humans; Metabolic Clearance Rate; Neoplasms; Protein Binding; Quinazolines; Thiophenes; Thymidylate Synthase | 2000 |
Raltitrexed/5-fluorouracil-based combination chemotherapy regimens in anticancer therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Neoplasm Metastasis; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Rectal Neoplasms; Thiophenes | 2001 |
Antifolates: the next generation.
Topics: Aminopterin; Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Clinical Trials as Topic; Drug Evaluation; Folic Acid Antagonists; Forecasting; Humans; Neoplasms; Pyrimidines; Quinazolines; Tetrahydrofolates; Thiophenes; Trimetrexate | 1992 |
31 trial(s) available for thiophenes and Neoplasms
| Article | Year |
|---|---|
A Phase I Dose-escalation Study of AZD3965, an Oral Monocarboxylate Transporter 1 Inhibitor, in Patients with Advanced Cancer.
Topics: Antineoplastic Agents; Dose-Response Relationship, Drug; Humans; Maximum Tolerated Dose; Neoplasms; Pyrimidinones; Thiophenes | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
First-in-human phase I trial of two schedules of OSI-930, a novel multikinase inhibitor, incorporating translational proof-of-mechanism studies.
Topics: Adult; Aged; Aged, 80 and over; Fatigue; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Positron-Emission Tomography; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinolines; Thiophenes; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neoplasms; Neuralgia; Peripheral Nervous System Diseases; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2013 |
Phase I, dose-escalation study of AZD7762 alone and in combination with gemcitabine in Japanese patients with advanced solid tumours.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Checkpoint Kinase 1; Checkpoint Kinase 2; Deoxycytidine; Dose-Response Relationship, Drug; Female; Gemcitabine; Humans; Japan; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Protein Kinases; Protein Serine-Threonine Kinases; Thiophenes; Urea | 2013 |
Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Checkpoint Kinase 1; Deoxycytidine; Dose-Response Relationship, Drug; Female; Gemcitabine; Humans; Male; Middle Aged; Neoplasms; Protein Kinases; Thiophenes; Urea | 2014 |
Phase I study of the MEK inhibitor trametinib in combination with the AKT inhibitor afuresertib in patients with solid tumors and multiple myeloma.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Dose-Response Relationship, Drug; Early Termination of Clinical Trials; Female; Humans; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Middle Aged; Multiple Myeloma; Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyridones; Pyrimidinones; Thiophenes; Tumor Burden | 2015 |
Phase I study of GSK461364, a specific and competitive Polo-like kinase 1 inhibitor, in patients with advanced solid malignancies.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzimidazoles; Binding, Competitive; Cell Cycle Proteins; Colorectal Neoplasms; Disease Progression; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Substrate Specificity; Thiophenes | 2011 |
Pilot study of duloxetine for cancer patients with neuropathic pain non-responsive to pregabalin.
Topics: Adult; Aged; Analgesics; Antidepressive Agents; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasms; Neuralgia; Pilot Projects; Pregabalin; Thiophenes | 2012 |
A phase 1 study of OSI-930 in combination with erlotinib in patients with advanced solid tumours.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Dose-Response Relationship, Drug; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Prognosis; Protein Kinase Inhibitors; Quinazolines; Quinolines; Thiophenes; Tissue Distribution | 2013 |
Phase I and pharmacokinetic study of irinotecan in combination with raltitrexed.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Diarrhea; Drug Administration Schedule; Fatigue; Female; Humans; Irinotecan; Male; Middle Aged; Neoplasms; Neutropenia; Quinazolines; Thiophenes | 2002 |
Raltitrexed-induced hepatotoxicity: multivariate analysis of predictive factors.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Female; Folic Acid Antagonists; Humans; Logistic Models; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Predictive Value of Tests; Quinazolines; Thiophenes; Transaminases | 2003 |
Population pharmacokinetics of raltitrexed in patients with advanced solid tumours.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Female; Humans; Male; Middle Aged; Neoplasms; Quinazolines; Thiophenes | 2004 |
A phase I pharmacokinetic and pharmacodynamic study of s-3304, a novel matrix metalloproteinase inhibitor, in patients with advanced and refractory solid tumors.
Topics: Aged; Antineoplastic Agents; Area Under Curve; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Indoles; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Maximum Tolerated Dose; Middle Aged; Neoplasms; Thiophenes | 2007 |
The toxicity of ICI D1694 in man and mouse.
Topics: Adult; Aged; Animals; Drug Administration Schedule; Female; Folic Acid Antagonists; Humans; Infusions, Intravenous; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Middle Aged; Neoplasms; Quinazolines; Thiophenes | 1993 |
Phase I trial of ZD1694, a new folate-based thymidylate synthase inhibitor, in patients with solid tumors.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Quinazolines; Thiophenes; Thymidylate Synthase | 1996 |
'Tomudex' (ZD1694): a novel thymidylate synthase inhibitor with clinical antitumour activity in a range of solid tumours. 'Tomudex' International Study Group.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Quinazolines; Survival Rate; Thiophenes; Thymidylate Synthase; Treatment Outcome | 1996 |
Phase I trial of a novel matrix metalloproteinase inhibitor batimastat (BB-94) in patients with advanced cancer.
Topics: Adult; Aged; Antineoplastic Agents; Collagenases; Drug Administration Schedule; Female; Gelatinases; Humans; Injections, Intraperitoneal; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Middle Aged; Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes | 1996 |
Metabolism, excretion and pharmacokinetics of a single dose of [14C]-raltitrexed in cancer patients.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Area Under Curve; Carbon Radioisotopes; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Neoplasms; Quinazolines; Radiopharmaceuticals; Thiophenes; Thymidylate Synthase | 1998 |
Phase I study of intraperitoneal metalloproteinase inhibitor BB94 in patients with malignant ascites.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Ascites; Dose-Response Relationship, Drug; Female; Humans; Male; Metalloendopeptidases; Middle Aged; Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes | 1998 |
Effects of impaired renal function on the pharmacokinetics of raltitrexed (Tomudex ZD1694).
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Drug Administration Schedule; Female; Humans; Kidney; Male; Middle Aged; Neoplasms; Quinazolines; Thiophenes | 1998 |
[Phase I study of raltitrexed (ZD-1694)].
Topics: Adult; Aged; Alanine Transaminase; Anorexia; Antimetabolites, Antineoplastic; Aspartate Aminotransferases; Colonic Neoplasms; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasms; Quinazolines; Thiophenes; Thymidylate Synthase | 1998 |
A Phase I study of raltitrexed and paclitaxel given every 3 weeks to patients with solid tumors.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Drug Administration Schedule; Drug Evaluation; Female; Humans; Lymphoma; Male; Middle Aged; Neoplasms; Neutropenia; Paclitaxel; Quinazolines; Thiophenes | 1999 |
A Phase I study of raltitrexed, an antifolate thymidylate synthase inhibitor, in adult patients with advanced solid tumors.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Folic Acid Antagonists; Humans; Male; Middle Aged; Neoplasms; Quinazolines; Thiophenes; Thymidylate Synthase | 1999 |
Phase I, dose-finding, and pharmacokinetic study of raltitrexed combined with oxaliplatin in patients with advanced cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Thiophenes; Treatment Outcome | 2000 |
Phase I study of mitoxantrone, raltitrexed, levofolinic acid and 5-fluorouracil in advanced solid tumours.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Middle Aged; Mitoxantrone; Neoplasms; Quinazolines; Thiophenes | 2001 |
Phase I trial of sequential administration of raltitrexed (Tomudex) and 5-iodo-2'-deoxyuridine (IdUrd).
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Humans; Idoxuridine; Male; Middle Aged; Neoplasms; Nucleic Acid Synthesis Inhibitors; Quinazolines; Thiophenes | 2001 |
Oltipraz chemoprevention trial in Qidong, People's Republic of China: results of urine genotoxicity assays as related to smoking habits.
Topics: Administration, Oral; Adult; Biomarkers; Chemoprevention; Escherichia coli; Female; Humans; Male; Mutagenicity Tests; Mutagens; Neoplasms; Pyrazines; Reproducibility of Results; Salmonella typhimurium; Smoking; Thiones; Thiophenes; Urine | 2001 |
Phase I clinical and pharmacogenetic trial of irinotecan and raltitrexed administered every 21 days to patients with cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Diarrhea; Dose-Response Relationship, Drug; Fatigue; Female; Genotype; Homocysteine; Humans; Irinotecan; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasms; Neutropenia; Oxidoreductases Acting on CH-NH Group Donors; Quinazolines; Thiophenes | 2001 |
Clinical screening of epipodophyllotoxin VM26 in malignant lymphomas and solid tumours.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Alopecia; Anemia, Aplastic; Antineoplastic Agents; Blood Platelet Disorders; Child; Clinical Trials as Topic; Female; Gastrointestinal Diseases; Glycosides; Hematopoiesis; Hodgkin Disease; Humans; Lactones; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllum; Remission, Spontaneous; Thiophenes; Urinary Bladder Neoplasms | 1972 |
Clinical studies with a new podophyllotoxin derivative, epipodophyllotoxin, 4'-demethyl-9-(4,6-O-2-thenylidine- -D-glucopyranoside) (NSC-122819).
Topics: Aged; Antineoplastic Agents; Astrocytoma; Clinical Trials as Topic; Esophageal Neoplasms; Evaluation Studies as Topic; Fibroblasts; Glycosides; Humans; Hypotension; Lactones; Leiomyosarcoma; Leukopenia; Liver Neoplasms; Lung Neoplasms; Melanoma; Middle Aged; Mitosis; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllum; Structure-Activity Relationship; Thiophenes; Thrombocytopenia | 1971 |
131 other study(ies) available for thiophenes and Neoplasms
| Article | Year |
|---|---|
Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design.
Topics: Amides; Animals; Binding Sites; Cell Line, Tumor; Drug Design; Enzyme Inhibitors; Half-Life; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Mice, Inbred ICR; Molecular Docking Simulation; Neoplasms; Structure-Activity Relationship; Thiophenes; Transplantation, Heterologous | 2022 |
Reasonable design of NIR AIEgens for fluorescence imaging and effective photothermal/photodynamic cancer therapy.
Topics: Humans; Nanoparticles; Neoplasms; Optical Imaging; Photochemotherapy; Thiophenes | 2022 |
Structure-Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists.
Topics: Animals; Humans; Immunotherapy; Interferons; Membrane Proteins; Mice; Neoplasms; Structure-Activity Relationship; Thiophenes; THP-1 Cells | 2022 |
A novel afterglow nanoreporter for monitoring cancer therapy.
Topics: Animals; Cell Line, Tumor; Mice; Nanoparticles; Neoplasms; Polymers; Pyrazines; Reactive Oxygen Species; Thiophenes | 2022 |
A water-soluble thiophene-croconaine dye with a high molar extinction coefficient for NIR fluorescence imaging-guided synergistic photothermal/photodynamic therapy of cancer.
Topics: Humans; Neoplasms; Optical Imaging; Photochemotherapy; Thiophenes; Water | 2022 |
π Bridge Engineering-Boosted Dual Enhancement of Type-I Photodynamic and Photothermal Performance for Mitochondria-Targeting Multimodal Phototheranostics of Tumor.
Topics: Cell Line, Tumor; Humans; Nanoparticles; Neoplasms; Photochemotherapy; Phototherapy; Photothermal Therapy; Reactive Oxygen Species; Theranostic Nanomedicine; Thiophenes | 2023 |
A new screening tool for FGFR inhibitor treatment?
Topics: Early Detection of Cancer; Humans; Neoplasms; Piperazines; Pyrroles; RNA, Messenger; Thiophenes | 2019 |
A sensitive and selective approach for detection of IL 1α cancer biomarker using disposable ITO electrode modified with epoxy-substituted polythiophene polymer.
Topics: Antibodies, Immobilized; Biomarkers, Tumor; Biosensing Techniques; Dielectric Spectroscopy; Epoxy Resins; Humans; Interleukin-1alpha; Neoplasms; Polymers; Thiophenes; Tin Compounds | 2019 |
D-A polymers for fluorescence/photoacoustic imaging and characterization of their photothermal properties.
Topics: Animals; Antineoplastic Agents; Female; Fluorescent Dyes; HeLa Cells; Humans; Hyperthermia, Induced; Infrared Rays; Liver; Mice, Nude; Nanoparticles; Neoplasms; Photoacoustic Techniques; Photochemotherapy; Polymers; Thiophenes; Xenograft Model Antitumor Assays | 2019 |
Semiconducting Polycomplex Nanoparticles for Photothermal Ferrotherapy of Cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Female; Ferroptosis; Infrared Rays; Iron; Iron Chelating Agents; Mice; Nanoparticles; Neoplasms; Photoacoustic Techniques; Photothermal Therapy; Polyethylene Glycols; Polymers; Reactive Oxygen Species; Semiconductors; Thiophenes | 2020 |
Dual emission nonionic molecular imprinting conjugated polythiophenes-based paper devices and their nanofibers for point-of-care biomarkers detection.
Topics: alpha-Fetoproteins; Biomarkers, Tumor; Biosensing Techniques; Carcinoembryonic Antigen; Humans; Limit of Detection; Molecularly Imprinted Polymers; Nanofibers; Neoplasms; Paper; Point-of-Care Testing; Polymers; Saliva; Smartphone; Thiophenes | 2020 |
Efficient near-infrared anionic conjugated polyelectrolyte for photothermal therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Female; Infrared Rays; Mice, Inbred BALB C; Neoplasms; Photothermal Therapy; Polyelectrolytes; Sulfonic Acids; Thiophenes | 2020 |
Thermosensitive Polymer Dot Nanocomposites for Trimodal Computed Tomography/Photoacoustic/Fluorescence Imaging-Guided Synergistic Chemo-Photothermal Therapy.
Topics: Animals; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Contrast Media; Doxorubicin; Drug Carriers; Humans; Hydrogels; Infrared Rays; Mice; Mice, Nude; Nanocomposites; Neoplasms; Optical Imaging; Photoacoustic Techniques; Photothermal Therapy; Polymers; Thiophenes; Tomography, X-Ray Computed | 2020 |
Combination of Inhibitors of USP7 and PLK1 has a Strong Synergism against Paclitaxel Resistance.
Topics: A549 Cells; Cell Cycle Proteins; Drug Resistance, Neoplasm; Humans; Neoplasms; Paclitaxel; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Thiophenes; Ubiquitin-Specific Peptidase 7 | 2020 |
In Vivo Bioimaging and Photodynamic Therapy Based on Two-Photon Fluorescent Conjugated Polymers Containing Dibenzothiophene-
Topics: Aniline Compounds; Animals; Cyclic S-Oxides; Fluorescent Dyes; HeLa Cells; Humans; Mice; Nanoparticles; Neoplasms; Optical Imaging; Photochemotherapy; Photons; Photosensitizing Agents; Polymers; Reactive Oxygen Species; Thiophenes | 2020 |
Near-infrared small molecule coupled with rigidness and flexibility for high-performance multimodal imaging-guided photodynamic and photothermal synergistic therapy.
Topics: A549 Cells; Animals; Antineoplastic Agents; Female; Fluorescent Dyes; Humans; Infrared Rays; Mice, Inbred BALB C; Mice, Nude; Multimodal Imaging; Neoplasms; Photochemotherapy; Photothermal Therapy; Precision Medicine; Thiophenes; Xenograft Model Antitumor Assays | 2021 |
A near-infrared and lysosomal targeting thiophene-BODIPY photosensitizer: Synthesis and its imaging guided photodynamic therapy of cancer cells.
Topics: Animals; Boron Compounds; Lysosomes; Neoplasms; Photochemotherapy; Photosensitizing Agents; Singlet Oxygen; Thiophenes; Zebrafish | 2021 |
Rational design of phenyl thiophene (pyridine) derivatives that overcome P-glycoprotein mediated MDR in MCF-7/ADR cell.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Pyridines; Structure-Activity Relationship; Thiophenes | 2021 |
Identification of Thieno[3,2-
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; fms-Like Tyrosine Kinase 3; Focal Adhesion Kinase 1; Humans; Mice, Inbred BALB C; Mice, Nude; Molecular Docking Simulation; Molecular Structure; Neoplasm Metastasis; Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; Structure-Activity Relationship; Thiophenes; Xenograft Model Antitumor Assays | 2021 |
A Small Molecule Strategy for Targeting Cancer Stem Cells in Hypoxic Microenvironments and Preventing Tumorigenesis.
Topics: Acetazolamide; Animals; Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carcinogenesis; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Curcumin; Diarylheptanoids; Fluorescent Dyes; Humans; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Neoplastic Stem Cells; Spheroids, Cellular; Thiophenes; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2021 |
Croconaine nanoparticles with enhanced tumor accumulation for multimodality cancer theranostics.
Topics: Animals; Cell Death; Coloring Agents; Combined Modality Therapy; Endocytosis; Female; Humans; MCF-7 Cells; Mice, Nude; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Photoacoustic Techniques; Polyethylene Glycols; Subcellular Fractions; Temperature; Theranostic Nanomedicine; Thiophenes | 2017 |
Water-Soluble Polythiophene for Two-Photon Excitation Fluorescence Imaging and Photodynamic Therapy of Cancer.
Topics: Fluorescence; Humans; Neoplasms; Photochemotherapy; Photons; Photosensitizing Agents; Polymers; Thiophenes; Water | 2017 |
Design, Synthesis and Anti-Proliferative Activities of 2,6-Substituted Thieno[3,2-d]pyrimidine Derivatives Containing Electrophilic Warheads.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Molecular Structure; Neoplasms; Pyrimidines; Structure-Activity Relationship; Thiophenes | 2017 |
Design, synthesis, in silico and in vitro evaluation of thiophene derivatives: A potent tyrosine phosphatase 1B inhibitor and anticancer activity.
Topics: Antineoplastic Agents; Cell Survival; Computer Simulation; Drug Design; Enzyme Inhibitors; Hep G2 Cells; Humans; MCF-7 Cells; Molecular Docking Simulation; Neoplasms; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Structure-Activity Relationship; Thiophenes | 2017 |
Highly absorbing multispectral near-infrared polymer nanoparticles from one conjugated backbone for photoacoustic imaging and photothermal therapy.
Topics: Animals; Female; HeLa Cells; Humans; Hyperthermia, Induced; Infrared Rays; Ketones; MCF-7 Cells; Mice, Inbred ICR; Nanoparticles; Neoplasms; Optical Imaging; Photoacoustic Techniques; Phototherapy; Pyrroles; Theranostic Nanomedicine; Thiophenes | 2017 |
pH Switchable Nanoassembly for Imaging a Broad Range of Malignant Tumors.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Screening Assays, Antitumor; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen-Ion Concentration; Ketones; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Neoplasms, Experimental; Pyrroles; Thiophenes; Tumor Microenvironment | 2017 |
Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence.
Topics: Animals; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Circadian Clocks; Female; Glioblastoma; GTP Phosphohydrolases; Humans; Lipogenesis; Male; Membrane Proteins; Mice, Inbred C57BL; Neoplasms; Nevus; Nuclear Receptor Subfamily 1, Group D, Member 1; Oncogenes; Pyrrolidines; Signal Transduction; Thiophenes | 2018 |
Curcumin induces a fatal energetic impairment in tumor cells in vitro and in vivo by inhibiting ATP-synthase activity.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Curcumin; Energy Metabolism; Female; Hexokinase; I-kappa B Kinase; L-Lactate Dehydrogenase; Malondialdehyde; Mice; Mice, Nude; Mitochondrial Proton-Translocating ATPases; Neoplasms; Neovascularization, Pathologic; Oxygen Consumption; Phosphofructokinases; Pyruvate Kinase; Reactive Oxygen Species; Thiophenes | 2018 |
Nucleoside Analogue-Based Supramolecular Nanodrugs Driven by Molecular Recognition for Synergistic Cancer Therapy.
Topics: Animals; Antineoplastic Agents; Clofarabine; Folic Acid; Folic Acid Antagonists; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Mice, Inbred BALB C; Mice, Nude; Molecular Dynamics Simulation; Nanoparticles; Neoplasms; Quinazolines; Rats; Thiophenes | 2018 |
Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and bone remodeling.
Topics: Animals; Bioprinting; Bone and Bones; Bone Remodeling; Calcification, Physiologic; Carbazoles; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Down-Regulation; Drug Screening Assays, Antitumor; Humans; Mice; Neoplasms; Osteoblasts; Osteoclasts; Osteogenesis; Printing, Three-Dimensional; Protein Kinase Inhibitors; RAW 264.7 Cells; Spheroids, Cellular; Thiophenes; Tumor Suppressor Protein p53; Urea; X-Ray Microtomography | 2018 |
Synthesis and in vitro antitumor evaluation of some new thiophenes and thieno[2,3-d]pyrimidine derivatives.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Neoplasms; Pyrimidines; Thiophenes | 2018 |
Rogaratinib: A potent and selective pan-FGFR inhibitor with broad antitumor activity in FGFR-overexpressing preclinical cancer models.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Female; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Phosphorylation; Piperazines; Pyrroles; Random Allocation; Rats; Receptors, Fibroblast Growth Factor; Thiophenes; Xenograft Model Antitumor Assays | 2019 |
Multivalent nanoparticles for personalized theranostics based on tumor receptor distribution behavior.
Topics: Animals; Cell Line, Tumor; Cell Survival; Contrast Media; Drug Carriers; Drug Delivery Systems; Endocytosis; Folate Receptors, GPI-Anchored; Gene Expression; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Neoplasms; Polyethyleneimine; Quinazolines; Theranostic Nanomedicine; Thiophenes; Xenograft Model Antitumor Assays | 2019 |
Polycyclic aromatic compounds in urban air and associated inhalation cancer risks: A case study targeting distinct source sectors.
Topics: Air Pollutants; Air Pollution; Anthracenes; Anthraquinones; Atmosphere; Canada; Environmental Monitoring; Fluorenes; Humans; Neoplasms; Nitrates; Nitrogen Oxides; Polycyclic Aromatic Hydrocarbons; Thiophenes; Vehicle Emissions | 2019 |
Fragment-based drug design and identification of HJC0123, a novel orally bioavailable STAT3 inhibitor for cancer therapy.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms; Quinolines; STAT3 Transcription Factor; Structure-Activity Relationship; Thiophenes | 2013 |
2-Aminothiophene-3-carboxylic acid ester derivatives as novel highly selective cytostatic agents.
Topics: Amino Acids; Apoptosis; Cell Cycle; Cell Line, Tumor; Cytostatic Agents; Esters; Humans; Neoplasms; Structure-Activity Relationship; Thiophenes | 2014 |
[Developing FGFR inhibitors as potential anti-cancer agents].
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Computer Simulation; Gene Expression Regulation, Neoplastic; Humans; Indoles; Mutation; Neoplasms; Oxindoles; Receptors, Fibroblast Growth Factor; Thiophenes; Up-Regulation | 2013 |
New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death.
Topics: Amines; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Ethers; HeLa Cells; Hep G2 Cells; Humans; MCF-7 Cells; Molecular Structure; Neoplasms; Pyridines; Structure-Activity Relationship; Thiophenes | 2013 |
Anilides and quinolones with nitrogen-bearing substituents from benzothiophene and thienothiophene series: synthesis, photochemical synthesis, cytostatic evaluation, 3D-derived QSAR analysis and DNA-binding properties.
Topics: Anilides; Antineoplastic Agents; Cell Line, Tumor; Cytostatic Agents; DNA; Drug Screening Assays, Antitumor; Humans; Neoplasms; Nitrogen; Quantitative Structure-Activity Relationship; Quinolones; Thiophenes; Topoisomerase II Inhibitors | 2014 |
Venous gangrene and intravascular coagulation and fibrinolysis in a patient treated with rivaroxaban.
Topics: Aged; Anticoagulants; Blood Coagulation; Female; Fibrinolysis; Gangrene; Humans; Lower Extremity; Morpholines; Neoplasms; Rivaroxaban; Thiophenes; Veins; Venous Thrombosis | 2014 |
Anti-cancer effect of thiacremonone through down regulation of peroxiredoxin 6.
Topics: Allografts; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Garlic; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Mice; Models, Molecular; Molecular Conformation; Mutation; Neoplasms; Peroxiredoxin VI; Plant Extracts; Protein Binding; Thiophenes; Tumor Burden | 2014 |
DNA hydrogel by multicomponent assembly for encapsulation and killing of cells.
Topics: Animals; Biocompatible Materials; Cations; Chelating Agents; Cross-Linking Reagents; DNA; Gadolinium; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogels; Jurkat Cells; Microscopy, Electron, Scanning; Neoplasms; Oxygen; Reactive Oxygen Species; Salmon; Thiophenes | 2014 |
A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation.
Topics: Animals; Biocompatible Materials; Carbon; Electron Spin Resonance Spectroscopy; Female; Graphite; HeLa Cells; Humans; Hydrogen-Ion Concentration; Light; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Molecular Weight; Nanostructures; Nanotechnology; Neoplasm Transplantation; Neoplasms; Oxygen; Photochemotherapy; Polymers; Porphyrins; Quantum Dots; Singlet Oxygen; Spectrophotometry, Ultraviolet; Thiophenes | 2014 |
ATR inhibition preferentially targets homologous recombination-deficient tumor cells.
Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Cell Survival; Checkpoint Kinase 1; Drug Resistance, Neoplasm; HeLa Cells; Homologous Recombination; Humans; MCF-7 Cells; Molecular Targeted Therapy; Neoplasms; Protein Kinases; Pyrazines; Signal Transduction; Sulfones; Thiophenes; Urea | 2015 |
Structure-activity relationship of tumor-selective 5-substituted 2-amino-3-carboxymethylthiophene derivatives.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; HeLa Cells; Humans; Neoplasms; Structure-Activity Relationship; Thiophenes | 2014 |
pH and DNA luminescence switching, DNA photocleavage and cytotoxic properties of two thiophene-containing ruthenium(II) complexes.
Topics: Animals; Antineoplastic Agents; Cattle; Cell Proliferation; Coordination Complexes; DNA; DNA Cleavage; Humans; Hydrogen-Ion Concentration; Light; Luminescence; Molecular Structure; Neoplasms; Organometallic Compounds; Quantum Theory; Ruthenium; Structure-Activity Relationship; Thiophenes; Tumor Cells, Cultured | 2014 |
Differential effects of AMPK agonists on cell growth and metabolism.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Biphenyl Compounds; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Glucose; HCT116 Cells; HEK293 Cells; Humans; Hypoglycemic Agents; Lactic Acid; Metformin; Mice; Neoplasms; Phenformin; Pyrones; Ribonucleotides; Sodium Salicylate; Thiophenes | 2015 |
Inhibition of monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport.
Topics: Animals; Biological Transport; Cell Line, Tumor; Cluster Analysis; Disease Models, Animal; Female; Glycolysis; Humans; Lactates; Metabolomics; Monocarboxylic Acid Transporters; Neoplasms; Oxidative Stress; Pyrimidinones; Radiation Tolerance; Symporters; Thiophenes; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Ligand-based pharmacophore modeling, atom-based 3D-QSAR and molecular docking studies on substituted thiazoles and thiophenes as polo-like kinase 1 (Plk1) inhibitors.
Topics: Antineoplastic Agents; Cell Cycle Proteins; Drug Design; Humans; Molecular Docking Simulation; Neoplasms; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Quantitative Structure-Activity Relationship; Thiazoles; Thiophenes | 2014 |
Disruption of the unfolded protein response (UPR) by lead compound selectively suppresses cancer cell growth.
Topics: Acetamides; Aniline Compounds; Animals; Antineoplastic Agents; Cell Growth Processes; Endoplasmic Reticulum Chaperone BiP; Female; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Neoplasms; Small Molecule Libraries; Thiophenes; Unfolded Protein Response; Xenograft Model Antitumor Assays | 2015 |
[Microtubule polymerization inhibitors].
Topics: Duloxetine Hydrochloride; Furans; Humans; Ketones; Microtubules; Neoplasms; Thiophenes; Tubulin Modulators; Vinca Alkaloids | 2015 |
The presence of primary cilia in cancer cells does not predict responsiveness to modulation of smoothened activity.
Topics: Cell Line, Tumor; Cilia; Cyclohexylamines; Epithelial Cells; Female; Fibroblasts; Hedgehog Proteins; Humans; MCF-7 Cells; Neoplasms; Piperazines; Pyrazoles; Receptors, G-Protein-Coupled; Signal Transduction; Smoothened Receptor; Thiophenes; Transcription Factors; Zinc Finger Protein GLI1 | 2015 |
Reduced graphene oxide modified smart conducting paper for cancer biosensor.
Topics: Biosensing Techniques; Carcinoembryonic Antigen; Electric Conductivity; Equipment Design; Graphite; Humans; Neoplasms; Paper; Point-of-Care Systems; Polystyrenes; Thiophenes | 2015 |
Survival After Solid Cancers in Antithrombotic Trials.
Topics: Female; Humans; Male; Middle Aged; Neoplasms; Piperazines; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Risk Factors; SEER Program; Survival Rate; Thiophenes | 2015 |
A self-assembled system for tumor-targeted co-delivery of drug and gene.
Topics: Acrylates; Chondroitin Sulfates; Drug Delivery Systems; Endocytosis; Gene Transfer Techniques; Hep G2 Cells; Humans; Imidazoles; Neoplasms; Plasmids; Polyethyleneimine; Thiophenes | 2015 |
Chemogenetic profiling identifies RAD17 as synthetically lethal with checkpoint kinase inhibition.
Topics: Antineoplastic Agents; Biomarkers, Pharmacological; Cell Cycle; Cell Cycle Proteins; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA Damage; DNA-Binding Proteins; Drug Discovery; HeLa Cells; Humans; Molecular Targeted Therapy; Mutation; Neoplasms; Nuclear Proteins; Protein Kinases; Protein-Tyrosine Kinases; RNA, Small Interfering; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiophenes; Urea | 2015 |
Two new bicyclic sulfoxides from Welsh onion.
Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cell Proliferation; Humans; Macrophages; Neoplasms; Onions; Plant Extracts; Plant Roots; Sulfoxides; Thiophenes | 2016 |
Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines.
Topics: Antineoplastic Agents; Benzoxazines; Cell Line, Tumor; Cell Proliferation; DNA-Activated Protein Kinase; Humans; Naphthalenes; Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Structure-Activity Relationship; Thiophenes | 2016 |
New derivative of 2-(2,4-dihydroxyphenyl)thieno-1,3-thiazin-4-one (BChTT) elicits antiproliferative effect via p38-mediated cell cycle arrest in cancer cells.
Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Molecular Structure; Neoplasms; p38 Mitogen-Activated Protein Kinases; Rats; Structure-Activity Relationship; Thiazines; Thiophenes | 2016 |
Amperometric sensing of HIF1α expressed in cancer cells and the effect of hypoxic mimicking agents.
Topics: Antibodies, Immobilized; Benzoates; Biosensing Techniques; Cell Line, Tumor; Electrochemical Techniques; Gold; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoassay; Metal Nanoparticles; Neoplasms; Polymers; Reproducibility of Results; Thiophenes | 2016 |
Novel 2-Thienyl- and 2-Benzothienyl-Substituted 6-(2-Imidazolinyl)Benzothiazoles: Synthesis; in vitro Evaluation of Antitumor Effects and Assessment of Mitochondrial Toxicity.
Topics: Antineoplastic Agents; Apoptosis; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Mitochondria; Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Thiophenes | 2017 |
The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation.
Topics: Actin Cytoskeleton; Aniline Compounds; Animals; Antigens, CD; beta Catenin; Cadherins; Cell Adhesion; Cell Membrane Permeability; Cell Movement; Chick Embryo; Chickens; Chorioallantoic Membrane; Fibroblast Growth Factors; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred C57BL; Neoplasms; Neovascularization, Physiologic; Stilbenes; Thiophenes; Tubulin Modulators; Vascular Endothelial Growth Factor A | 2016 |
A Donor-Acceptor Conjugated Polymer with Alternating Isoindigo Derivative and Bithiophene Units for Near-Infrared Modulated Cancer Thermo-Chemotherapy.
Topics: Cell Line, Tumor; Drug Liberation; Drug Therapy; Humans; Indoles; Nanoparticles; Neoplasms; Photosensitizing Agents; Polymers; Thiophenes | 2016 |
Evaluation of the antiproliferative activity of 2-amino thiophene derivatives against human cancer cells lines.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Humans; Mice; Neoplasms; Thiophenes | 2016 |
Direct determination of small RNAs using a biotinylated polythiophene impedimetric genosensor.
Topics: Biosensing Techniques; Biotinylation; Cell Line, Tumor; Dielectric Spectroscopy; Humans; Limit of Detection; MicroRNAs; Neoplasms; Polymers; Thiophenes | 2017 |
Bioconjugation and Applications of Amino Functional Fluorescence Polymers.
Topics: A549 Cells; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Neoplasms; Polymers; Radiation Tolerance; Radiation-Sensitizing Agents; Receptor, ErbB-2; Thiophenes | 2017 |
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Line, Tumor; Female; Humans; Leukemia; Lymphoma; Male; Mice; Models, Biological; Models, Molecular; Multiple Myeloma; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms; Pyrimidines; Thiophenes; Xenograft Model Antitumor Assays | 2016 |
Highly sensitive detection of cancer cells with an electrochemical cytosensor based on boronic acid functional polythiophene.
Topics: Biosensing Techniques; Bone Marrow Cells; Boronic Acids; Cell Separation; Dielectric Spectroscopy; Gold; Graphite; HEK293 Cells; Humans; Mesenchymal Stem Cells; Metal Nanoparticles; Neoplasms; Polymers; Thiophenes | 2017 |
Anticancer drugs: Breaking up a pro-survival interaction.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Design; Humans; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms; Pyrimidines; Thiophenes | 2016 |
S63845, an MCL-1 Selective BH3 Mimetic: Another Arrow in Our Quiver.
Topics: Animals; Apoptosis; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Molecular Targeted Therapy; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms; Pyrimidines; Thiophenes | 2016 |
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity.
Topics: AMP-Activated Protein Kinases; Animals; Antibodies, Monoclonal; Biphenyl Compounds; Cell Line, Tumor; Cytokines; Lymph Nodes; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Morpholines; Neoplasms; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Programmed Cell Death 1 Receptor; Pyrones; Reactive Oxygen Species; T-Lymphocytes, Cytotoxic; Thiophenes; TOR Serine-Threonine Kinases; Triazines | 2017 |
Lactate Detection in Tumor Cell Cultures Using Organic Transistor Circuits.
Topics: Animals; Biosensing Techniques; Calibration; Cattle; Cell Culture Techniques; Chitosan; Electric Impedance; Electrochemical Techniques; Equipment Design; Ferrous Compounds; Humans; Lactic Acid; Leukocytes, Mononuclear; Metallocenes; Mixed Function Oxygenases; Neoplasms; Polystyrenes; Sensitivity and Specificity; Serum Albumin, Bovine; Thiophenes; Transistors, Electronic | 2017 |
Synthesis and CHK1 inhibitory potency of Hymenialdisine analogues.
Topics: Antineoplastic Agents; Azepines; Checkpoint Kinase 1; Chemistry, Pharmaceutical; Drug Design; Drug Screening Assays, Antitumor; Electrons; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Structure; Neoplasms; Protein Kinases; Pyrroles; Structure-Activity Relationship; Thiophenes | 2009 |
Effect of the multitargeted receptor tyrosine kinase inhibitor, ABT-869 [N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea], on blood pressure in conscious rats and mice: reversal with antihypertensive agents and effect on tumor growt
Topics: Acrylates; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enalapril; Humans; Imidazoles; Indazoles; Lisinopril; Male; Mice; Mice, SCID; Neoplasms; Nifedipine; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Ramipril; Rats; Rats, Sprague-Dawley; Telmisartan; Thiophenes; Xenograft Model Antitumor Assays | 2009 |
Endogenous activated protein C limits cancer cell extravasation through sphingosine-1-phosphate receptor 1-mediated vascular endothelial barrier enhancement.
Topics: Animals; Antibodies, Monoclonal; Anticoagulants; Antigens, CD; Cadherins; Endothelium, Vascular; Evans Blue; Female; Melanoma, Experimental; Mice; Models, Biological; Neoplasms; Oxadiazoles; Protein C; Receptors, Lysosphingolipid; Signal Transduction; Thiophenes | 2009 |
Distinct concentration-dependent effects of the polo-like kinase 1-specific inhibitor GSK461364A, including differential effect on apoptosis.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Biomarkers, Tumor; Cell Cycle Proteins; Cell Line, Tumor; Clinical Trials as Topic; Dose-Response Relationship, Drug; G2 Phase; Humans; Mice; Mice, Nude; Mitosis; Neoplasms; Neoplasms, Experimental; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Thiophenes | 2009 |
Weighing benefits and risks--the FDA's review of prasugrel.
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Causality; Clinical Trials as Topic; Combined Modality Therapy; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Neoplasms; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; United States; United States Food and Drug Administration | 2009 |
Hydrogen peroxide is a second messenger in phase 2 enzyme induction by cancer chemopreventive dithiolethiones.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cyclic N-Oxides; Diglycerides; Enzyme Induction; Hepatocytes; Humans; Hydrogen Peroxide; NAD(P)H Dehydrogenase (Quinone); Neoplasms; Pyrazines; Second Messenger Systems; Thiones; Thiophenes | 2009 |
Prasugrel: new drug. After angioplasty and stenting: continue to use aspirin + clopidogrel.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Drug-Eluting Stents; Europe; Hemorrhage; Humans; Ischemic Attack, Transient; Myocardial Infarction; Neoplasms; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Recurrence; Stents; Stroke; Thiophenes; Ticlopidine; Treatment Outcome | 2009 |
In vitro and in vivo radiation sensitization of human tumor cells by a novel checkpoint kinase inhibitor, AZD7762.
Topics: Animals; Cells, Cultured; Checkpoint Kinase 1; DNA Damage; Dose-Response Relationship, Drug; Female; G2 Phase; HT29 Cells; Humans; Mice; Mice, Nude; Mitotic Index; Neoplasms; Protein Kinase Inhibitors; Protein Kinases; Radiation Tolerance; Radiation-Sensitizing Agents; Thiophenes; Urea; Xenograft Model Antitumor Assays | 2010 |
Phosphorescent light-emitting iridium complexes serve as a hypoxia-sensing probe for tumor imaging in living animals.
Topics: Animals; Cell Hypoxia; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Female; HeLa Cells; HT29 Cells; Humans; Iridium; Luminescent Measurements; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Organometallic Compounds; Oxygen; Partial Pressure; Photochemical Processes; Pyridines; Thiophenes; Tissue Distribution; Transplantation, Heterologous | 2010 |
Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability.
Topics: Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromosomal Instability; Cyclin-Dependent Kinase Inhibitor p21; Humans; Immunoblotting; Inhibitory Concentration 50; Mitosis; Mutation; Neoplasms; Polo-Like Kinase 1; Polyploidy; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Thiophenes; Time Factors; Tumor Suppressor Protein p53 | 2010 |
Substituted 2-(3',4',5'-trimethoxybenzoyl)-benzo[b]thiophene derivatives as potent tubulin polymerization inhibitors.
Topics: Animals; Anisoles; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Models, Molecular; Neoplasms; Rats; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators | 2010 |
Benzo[b]thiophene-6-carboxamide 1,1-dioxides: inhibitors of human cancer cell growth at nanomolar concentrations.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Neoplasms; Reactive Oxygen Species; Thiophenes | 2010 |
Prasugrel and cancer.
Topics: Clinical Trials as Topic; Clopidogrel; Humans; Neoplasms; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine | 2010 |
Platelet inhibition and cancer promotion.
Topics: Animals; Endothelium, Vascular; Humans; Neoplasms; Neovascularization, Pathologic; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Spleen; Stem Cells; T-Lymphocytes, Regulatory; Thiophenes | 2010 |
Bayesian hierarchical changepoint methods in modeling the tumor growth profiles in xenograft experiments.
Topics: Animals; Bayes Theorem; Cell Proliferation; Confidence Intervals; Deoxycytidine; Gemcitabine; Mice; Models, Biological; Models, Statistical; Neoplasms; Thiophenes; Urea; Xenograft Model Antitumor Assays | 2011 |
An in-vitro evaluation of the polo-like kinase inhibitor GW843682X against paediatric malignancies.
Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Benzimidazoles; Blotting, Western; Camptothecin; Caspases; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Child; Coloring Agents; Enzyme Activation; Enzyme Inhibitors; Humans; Neoplasms; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thiophenes; Topoisomerase I Inhibitors | 2011 |
Log-scale dose response of inhibitors on a chip.
Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Kinetics; Lab-On-A-Chip Devices; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Microchip Analytical Procedures; Neoplasms; Phenylalanine; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiophenes | 2011 |
Oral bisphosphonate use increases the risk for inflammatory jaw disease: a cohort study.
Topics: Administration, Oral; Aged; Alcoholism; Alendronate; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Case-Control Studies; Cohort Studies; Denmark; Diabetes Complications; Diphosphonates; Drug Therapy; Etidronic Acid; Female; Humans; Jaw Diseases; Male; Neoplasms; Organometallic Compounds; Osteitis; Osteomyelitis; Osteoporosis; Parathyroid Hormone; Periostitis; Radiotherapy; Raloxifene Hydrochloride; Risk Factors; Sjogren's Syndrome; Strontium; Thiophenes | 2012 |
1,3‑Propane sultone.
Topics: Animals; Carcinogens; Environmental Exposure; Humans; Neoplasms; Thiophenes | 2011 |
Heterocyclic compounds as carbonic anhydrase inhibitor.
Topics: Acid-Base Equilibrium; Antineoplastic Agents; Azoles; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Epilepsy; Glaucoma; Humans; Hypoxia; Indoles; Isoenzymes; Neoplasms; Structure-Activity Relationship; Sulfonamides; Thiophenes | 2012 |
A novel DNA intercalator, 8-methoxy pyrimido[4',5':4,5]thieno (2,3-b)quinoline-4(3H)-one induces apoptosis in cancer cells, inhibits the tumor progression and enhances lifespan in mice with tumor.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; DNA; DNA Breaks, Double-Stranded; Humans; Intercalating Agents; Leukemia; Mice; Mice, Inbred BALB C; Neoplasms; Quinolines; Reactive Oxygen Species; Signal Transduction; Thiophenes | 2013 |
Extraskeletal benefits and risks of calcium, vitamin D and anti-osteoporosis medications.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Calcium; Cardiovascular Diseases; Consensus; Denosumab; Dietary Supplements; Diphosphonates; Female; Humans; Male; Middle Aged; Muscle, Skeletal; Neoplasms; Organometallic Compounds; Osteoporosis; Selective Estrogen Receptor Modulators; Stroke; Thiophenes; Vitamin D | 2012 |
Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chromones; DNA-Activated Protein Kinase; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Female; Humans; MCF-7 Cells; Mice; Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Thiophenes; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
1,3-Propane sultone as an extremely potent human carcinogen: description of an exposed cohort in Germany.
Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Carcinogens; Chemical Industry; Cohort Studies; Germany; Glioblastoma; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Occupational Diseases; Occupational Exposure; Thiophenes | 2012 |
Preliminary antifungal and cytotoxic evaluation of synthetic cycloalkyl[b]thiophene derivatives with PLS-DA analysis.
Topics: Antifungal Agents; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Candida; Cell Line, Tumor; Cell Proliferation; Cryptococcus neoformans; Discriminant Analysis; Drug Design; Fungi; Humans; Indoles; Least-Squares Analysis; Microbial Sensitivity Tests; Molecular Structure; Neoplasms; Nitriles; Structure-Activity Relationship; Thiophenes; Transition Temperature | 2012 |
Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects.
Topics: Acetamides; Animals; Benzoquinones; Blotting, Western; Cell Line, Tumor; Drug Discovery; High-Throughput Screening Assays; HSP90 Heat-Shock Proteins; Humans; Imidazoles; Immunoprecipitation; Intramolecular Oxidoreductases; Lactams, Macrocyclic; Lead; Luciferases, Firefly; Luciferases, Renilla; Mice; Mice, Nude; Neoplasms; Positron-Emission Tomography; Prostaglandin-E Synthases; Protein Folding; Protein Isoforms; Pyrazines; Small Molecule Libraries; Thioacetamide; Thiophenes; Tomography, X-Ray Computed; Tritium | 2012 |
Low band gap donor-acceptor conjugated polymer nanoparticles and their NIR-mediated thermal ablation of cancer cells.
Topics: Azoles; Cell Survival; Colorectal Neoplasms; Hot Temperature; Humans; Hyperthermia, Induced; Infrared Rays; Nanoparticles; Neoplasms; Organoselenium Compounds; Polymers; Thiadiazoles; Thiophenes | 2013 |
Periprocedural anticoagulant management.
Topics: Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Coronary Restenosis; Dabigatran; Heart Valve Prosthesis; Hemorrhage; Humans; Morpholines; Neoplasms; Perioperative Care; Risk Assessment; Rivaroxaban; Stents; Thiophenes; Venous Thromboembolism; Warfarin | 2012 |
Prospective evaluation of the frequency and treatment of restless legs syndrome in a palliative care unit.
Topics: Aged; Dopamine Agonists; Female; Hospital Units; Humans; Male; Middle Aged; Neoplasms; Palliative Care; Prospective Studies; Restless Legs Syndrome; Tetrahydronaphthalenes; Thiophenes | 2012 |
DAT-230, a Novel Microtubule Inhibitor, Induced Aberrant Mitosis and Apoptosis in SGC-7901 Cells.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mitosis; Neoplasms; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Thiophenes; Tubulin Modulators; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Pharmacokinetics studies and toxicity profile of raltitrexed used by intraperitoneal route in normothermia in a pig model.
Topics: Animals; Antimetabolites, Antineoplastic; Body Temperature; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Injections, Intraperitoneal; Models, Statistical; Neoplasms; Quinazolines; Swine; Thiophenes; Time Factors | 2003 |
A flexible route to (5R)-thiolactomycin, a naturally occurring inhibitor of fatty acid synthesis.
Topics: Acetyltransferases; Alanine; Anti-Bacterial Agents; Fatty Acid Synthase, Type II; Fatty Acids; Humans; Multienzyme Complexes; Neoplasms; Obesity; Stereoisomerism; Thiophenes | 2002 |
A "combination oligonucleotide" antisense strategy to downregulate thymidylate synthase and decrease tumor cell growth and drug resistance.
Topics: Antineoplastic Agents; Cell Division; Down-Regulation; Drug Resistance, Neoplasm; Female; Fluorouracil; HeLa Cells; Humans; Neoplasms; Oligodeoxyribonucleotides, Antisense; Quinazolines; RNA, Messenger; Thiophenes; Thymidylate Synthase | 2003 |
The chemical control of pituitary function in relation to chemotherapy of cancer.
Topics: Amino Acids; Animals; Ethylenes; Neoplasms; Neoplasms, Experimental; Pituitary Diseases; Pituitary Gland; Thiophenes | 1957 |
Inhibition of tumour growth by interference of hexose mono-phosphate pathway. Synthesis and anticancer properties of thiophene 2 : 5 dicarboxylic acid.
Topics: Animals; Antineoplastic Agents; Dicarboxylic Acids; Hexosephosphates; Hexoses; Neoplasms; Neoplasms, Experimental; Phosphates; Thiophenes | 1960 |
INHIBITION OF TUMOUR GROWTH WITH ANTIMETABOLITES OF HEXOSE MONOPHOSPHATE PATHWAY INTERMEDIATES.
Topics: Antimetabolites; Antineoplastic Agents; Carbohydrate Metabolism; Fibrosarcoma; Furans; Hexosephosphates; Hexoses; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Pyrrolidinones; Rats; Research; Sarcoma, Yoshida; Sulfhydryl Compounds; Thiophenes | 1964 |
[CLINICAL EXPERIENCES ON THE EFFECT OF THE ORAL APPLICATION OF N-ACETYLHOMOCYSTEINE THIOLACTONE ON THE INTESTINAL REACTION IN RADIOTHERAPY OF GYNECOLOGICAL CARCINOMA].
Topics: Carcinoma; Female; Genital Neoplasms, Female; Humans; Neoplasms; Pharmacology; Radiation-Protective Agents; Thiophenes | 1964 |
Evaluation of the cancer chemopreventive potency of dithiolethione analogs of oltipraz.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Blotting, Western; Carcinogens; DNA; DNA Adducts; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Immunoblotting; Liver; Male; Models, Chemical; Neoplasms; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Pyrazines; Rats; Rats, Inbred F344; RNA; RNA, Messenger; Temperature; Thiones; Thiophenes; Time Factors | 2003 |
The role of alpha-folate receptor-mediated transport in the antitumor activity of antifolate drugs.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cell Line, Tumor; Cytosol; Dose-Response Relationship, Drug; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Inhibitory Concentration 50; Models, Chemical; Neoplasms; Pemetrexed; Quinazolines; Receptors, Cell Surface; Thiophenes; Time Factors | 2004 |
Benzo[b]thiophenesulphonamide 1,1-dioxide derivatives inhibit tNOX activity in a redox state-dependent manner.
Topics: Antineoplastic Agents; Enzyme Inhibitors; Humans; NADH, NADPH Oxidoreductases; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Sulfonamides; Thiophenes; Tumor Cells, Cultured | 2005 |
New approaches to preventing xerostomia.
Topics: Amifostine; Cytoprotection; Humans; Muscarinic Agonists; Neoplasms; Pilocarpine; Quinuclidines; Radiation Injuries; Radiation-Protective Agents; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Salivary Glands; Thiophenes; Xerostomia | 2006 |
A general approach for sample size and statistical power calculations assessing of interventions using a mixture model in the presence of detection limits.
Topics: Anticarcinogenic Agents; Clinical Trials as Topic; Computer Simulation; Humans; Models, Statistical; Monte Carlo Method; Neoplasms; Pyrazines; Sample Size; Thiones; Thiophenes | 2006 |
Combination silencer RNA (siRNA) targeting Bcl-2 antagonizes siRNA against thymidylate synthase in human tumor cell lines.
Topics: Cell Line, Tumor; Cell Proliferation; Docetaxel; Floxuridine; G1 Phase; Humans; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Quinazolines; RNA, Messenger; RNA, Small Interfering; Taxoids; Thiophenes; Thymidylate Synthase | 2007 |
Interactions of the major metabolite of the cancer chemopreventive drug oltipraz with cytochrome c: a novel pathway for cancer chemoprevention.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Chemoprevention; Cytochromes c; Electron Spin Resonance Spectroscopy; Electron Transport; Heart; Horses; Mass Spectrometry; Mitochondria; Neoplasms; Oxidation-Reduction; Peroxidase; Pyrazines; Reactive Oxygen Species; Spectrophotometry, Ultraviolet; Thiones; Thiophenes | 2007 |
Fluorouracil: active in ZD1694 (tomudex)-resistant cell lines with markedly elevated thymidylate synthase levels.
Topics: Drug Resistance; Fluorouracil; Humans; Neoplasms; Quinazolines; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 1995 |
Matrix metalloproteinase inhibitors: a novel class of anticancer agents.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Humans; Melanoma, Experimental; Metalloendopeptidases; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes | 1995 |
Interaction of tomudex with radiation in vitro and in vivo.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Lewis Lung; Carcinoma, Squamous Cell; Cell Survival; Combined Modality Therapy; Drug Interactions; Enzyme Inhibitors; Fluorouracil; Head and Neck Neoplasms; HT29 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms; Quinazolines; Radiation Tolerance; Thiophenes; Thymidylate Synthase; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
Batimastat. BB 94, collagenase inhibitors-1.
Topics: Animals; Antineoplastic Agents; Ascites; Drugs, Investigational; Humans; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Neoplasms; Phenylalanine; Pleural Effusion, Malignant; Protease Inhibitors; Thiophenes | 1999 |
Schedule-dependent interactions between raltitrexed and cisplatin in human carcinoma cell lines in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Humans; Neoplasms; Quinazolines; Thiophenes; Tumor Cells, Cultured | 2000 |
Fatal liver failure after the administration of raltitrexed for cancer chemotherapy: a report of two cases.
Topics: Aged; Antimetabolites, Antineoplastic; Fatal Outcome; Female; Humans; Liver Failure; Male; Middle Aged; Neoplasms; Quinazolines; Thiophenes | 2000 |
Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy.
Topics: Animals; Apoptosis; Hepatitis, Animal; Humans; Interferon-gamma; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms; Phenylalanine; Protease Inhibitors; Recombinant Proteins; Thiophenes; Tumor Necrosis Factor-alpha | 2001 |
Characterization of a thymidylate synthase (TS)-inducible cell line: a model system for studying sensitivity to TS- and non-TS-targeted chemotherapies.
Topics: Blotting, Northern; Blotting, Western; Camptothecin; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Cisplatin; Cyclin A; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Fluorouracil; Folic Acid Antagonists; Gene Expression Regulation, Enzymologic; Humans; Irinotecan; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Protein Serine-Threonine Kinases; Quinazolines; RNA, Messenger; Tetracycline; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 2001 |
Combined chemotherapy trials require combined pharmacogenetic approaches.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Enzyme Inhibitors; Humans; Irinotecan; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Quinazolines; Thiophenes | 2002 |
Oltipraz protects the passive smoke induced changes in renal glyoxalase system of rats.
Topics: Animals; Anticarcinogenic Agents; Female; Kidney; Lactoylglutathione Lyase; Neoplasms; Pyrazines; Rats; Rats, Sprague-Dawley; Thiolester Hydrolases; Thiones; Thiophenes; Tobacco Smoke Pollution | 2002 |
[Kinetics of I-131 fibrinogen in cancer patients: pharmacological approach].
Topics: Aspirin; Blood Coagulation; Fibrinogen; Fibrinolytic Agents; Heparin; Indomethacin; Iodine Radioisotopes; Kinetics; Neoplasms; Platelet Aggregation; Prednisone; Pyridines; Thiophenes | 1977 |
Carcinogenic and other protective effects of dithiolthiones.
Topics: Animals; Antioxidants; Brassica; Disulfides; Humans; Mice; Neoplasms; Rats; Structure-Activity Relationship; Thiones; Thiophenes; Vegetables | 1986 |
Clinical investigation of a new podophyllum derivative, epipodophyllotoxin, 4'-demethyl-9-(4,6-O-2-thenylidene- -D-glucopyranoside) (NSC-122819), in patients with malignant lymphomas and solid tumors.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Female; Glycosides; Haplorhini; Hodgkin Disease; Humans; Immunosuppression Therapy; Lactones; Lymphoma; Male; Mice; Middle Aged; Neoplasms; Neoplasms, Experimental; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Rats; Thiophenes | 1972 |
Ticarcillin therapy of infections.
Topics: Adult; Bacterial Infections; Carboxylic Acids; Humans; Leukemia; Neoplasms; Penicillins; Pseudomonas Infections; Thiophenes | 1973 |
Clinical pharmacology of ticarcillin (alpha-carboxyl-3-thienylmethyl penicillin, BRL-2288).
Topics: Adolescent; Adult; Aged; Carboxylic Acids; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney Diseases; Leukemia; Middle Aged; Neoplasms; Penicillins; Thiophenes; Time Factors | 1973 |