Compounds > thiophenes
Page last updated: 2024-08-18

thiophenes and Muscle Contraction

thiophenes has been researched along with Muscle Contraction in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199032 (42.11)18.7374
1990's14 (18.42)18.2507
2000's15 (19.74)29.6817
2010's14 (18.42)24.3611
2020's1 (1.32)2.80

Authors

AuthorsStudies
Drimousis, S; Liu, L; Markus, I; Murphy, TV; Perera, DS; Phan-Thien, KC; Zhang, L1
Miyamoto, L1
Kullmann, FA; Langdale, CL; Thor, KB; Wells, GI; Zheng, J1
Barreiro, EJ; Caruso-Neves, C; da Silva, JS; Fraga, CA; Kümmerle, AE; Landgraf, SS; Maia, Rdo C; Pereira, SL; Sudo, RT; Zapata-Sudo, G1
Giuliani, S; Lecci, A; Maggi, CA; Meini, S; Santicioli, P1
Foretz, M; Hallén, S; Kviklyte, S; Lai, YC; Lantier, L; Rider, MH; Vertommen, D; Viollet, B1
Gallego, D; Jimenez, M; Mañé, N; Martin, MT; Martinez-Cutillas, M1
Duthie, KM; Hadoke, PW; Ivy, JR; Kirkby, NS; Lim, WG; McShane, JF; Miller, E; Webb, DJ1
Avdonin, PP; Avdonin, PV; Goncharov, NV; Jenkins, RO; Mironova, GY1
Davenport, EA; Gardner, SD; Hieble, JP; Hoffman, BE; Laping, NJ; Lashinger, ES; Leon, LA; Nagilla, R; Steiginga, MS; Su, X1
Boy, S; Mehnert, U; Reitz, A; Schurch, B; Widmer-Simitovic, S1
Antunes, F; Barreiro, EJ; Beiral, HJ; Fraga, CA; Kummerle, AE; Pereira, SL; Raimundo, JM; Sudo, RT; Zapata-Sudo, G1
Altamura, M; Catalioto, RM; D'Andrea, P; Ettorre, A; Fattori, D; Giuliani, S; Maggi, CA; Marastoni, E; Mauro, S; Meini, S; Porcelloni, M; Rossi, C1
Colucci, M; Di Giannuario, A; Maione, F; Mascolo, N; Mastriota, M; Palmery, M; Perretti, M; Pieretti, S; Severini, C1
Castriota, F; Grzesk, E; Grzesk, G; Kozinski, M; Krzyzanowski, M; Kubica, A; Kubica, J; Navarese, EP; Siller-Matula, JM1
Andrews, JS; Annedi, SC; Maddaford, SP; Mladenova, G; Porreca, F; Rakhit, S; Ramnauth, J; Zhang, D1
Adamakis, I; Constantinides, CA; Vasileiou, I1
LEWIS, JJ; MARTIN-SMITH, M; MUIR, TC; NANJAPPA, SN; REID, ST1
Bump, RC; Yalcin, I1
Araldi, D; Goncales, CE; Nogueira, CW; Panatieri, RB; Rocha, JB; Zeni, G1
Barreiro, EJ; Fraga, CA; Kummerle, AE; Silva, AG; Sudo, RT; Zapata-Sudo, G1
Boy, S; Braun, PM; Haferkamp, A; Knapp, PA; Reitz, A; Schurch, B; Wirth, B1
García, L; Grandoso, L; Pineda, J; Ugedo, L1
Altamura, M; Catalani, C; Catalioto, RM; Cialdai, C; Giuliani, S; Lecci, A; Maggi, CA; Meini, S; Patacchini, R; Tramontana, M; Valenti, C1
Bellucci, C; Buccioni, M; Dei, S; Ferraroni, M; Guandalini, L; Manetti, D; Martini, E; Marucci, G; Matucci, R; Nesi, M; Romanelli, MN; Scapecchi, S; Teodori, E1
Altamura, M; Catalioto, RM; Fedi, V; Giannotti, D; Giolitti, A; Giuliani, S; Guidi, A; Harmat, NJ; Lecci, A; Maggi, CA; Meini, S; Nannicini, R; Pasqui, F; Tramontana, M; Triolo, A1
Becker, T; Gros, G; Hallerdei, J; Mundhenk, K; Scheibe, RJ; Shah, GN; Sly, WS; Waheed, A; Wetzel, P1
Altamura, M; D'Andrea, P; Ettorre, A; Fattori, D; Giuliani, S; Madami, A; Meini, S; Porcelloni, M; Rossi, C; Sisto, A1
Gessner, PK; Godse, DD; Winter, JC1
Faghihi, SM; Hedayati, MA; Salimi, MM; Shafiee, A1
Lowe, DA; Richardson, BP1
Magaribuchi, T; Nakajima, H; Takenaga, H1
Eglen, RM; Flippin, LA; Kim, EJ; Lazar, DA; Leung, E; Seran, CS; Walsh, LK; Wong, EH1
Katofiasc, MA; Thor, KB1
Boura, AL; Bremner, JB; Browne, EJ; King, RG; Leitch, IM; Rawlow, A1
Duckles, SP; Friedman, DJ1
Cheng, X; Palacios, B; Pang, CC1
Cadavid, MI; Carotti, A; Carrieri, A; Cid, J; Fontenla, JA; Loza, MI; Lozoya, E; Masaguer, CF; Negreira, J; Raviña, E; Rivas, ME; Rosa, E; Sanz, F; Tristán, H1
Nass, JU; Nuskovski, M; Thieme, H; Wiederholt, M1
Albuquerque, EX; Aracava, Y; Barreiro, EJ; Castro, NG; Chang, R; Fraga, CA; Gonzalez-Serratos, H; Lima, PC; Melo, PA; Pereira, EF1
Arisawa, H; Fujise, N; Fukui, K; Masunaga, H1
Bousquet, E; Prezzavento, O; Ronsisvalle, G; Santagati, NA; Spampinato, S1
Awouters, F; De Clerck, F; Hoebeke, J; Janssen, PA; Van Nueten, JM1
Van Nueten, JM1
Marchini, F; Pesce, E; Piacenza, G; Rotta, C1
Bert, H; Dureng, G; Labrid, C1
Bosin, TR; Campaigne, EE1
Aurousseau, M; Boissier, JR; Duval, D; Giudicelli, JF1
Cargnelli, G; Finotti, P; Gobbato, S; Padrini, R1
Saito, K; Tamaki, H1
Bekemeier, H; Köster, D1
Boey, JM; De Bruyn, MF; Janssen, PA; Sipido, VK; Van Daele, PG1
Janssen, PA; Niemegeers, CJ; Van Bruggen, JA1
Duckles, SP; Friedman, DJ; Krause, DN1
Bond, RA; Vanhoutte, PM1
Boonen, HC; De Mey, JG; Struyker-Boudier, HA1
Harada, M; Hidaka, K; Konishi, T; Tamura, T; Terai, M; Tsukamoto, S; Usuda, S; Wanibuchi, F1
Burke, JA; Chan, MF; Crosson, CE; Potter, DE1
Dissanayake, VU; Hill, RG; Hughes, J; Hunter, JC1
Russo, F; Santagati, NA; Spampinato, S; Venturini, R1
Allen, GS; Banghart, SB; Peroutka, SJ1
Birchmore, B; Clark, CR; Hill, RG; Hughes, J; Hunter, JC; Sharif, NA1
Angeli, P; Brasili, L; Giannella, M; Gualtieri, F; Picchio, MT; Teodori, E1
Angeli, P; Brasili, L; Gualtieri, F; Romanelli, MN; Teodori, E1
Angeli, P; Brasili, L; Gualtieri, F; Romanelli, MN; Valle, G1
Angeli, P; Brasili, L; Giannella, M; Gualtieri, F; Pigini, M; Teodori, E1
Oka, N; Washida, H1
Corral, C; Darias, V; Del Río, J; Fernández-Tomé, MP; Madroñero, R1
Bamgbose, SO1
Bamgbose, SO; Marquis, VO; Salako, LA1
Damas, J1
Harigaya, S; Kiyomoto, A; Murata, S; Tamaki, H; Tanaka, M1
Albin, MS; Massopust, LC; Wolin, LR1
Dunn, FW; Stewart, JM1
Green, DM; Pinder, RM; Thompson, PB1
Albers, R; Biggerstaff, WR; Sugisaka, N1

Reviews

3 review(s) available for thiophenes and Muscle Contraction

ArticleYear
[AMPK as a Metabolic Intersection between Diet and Physical Exercise].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2018, Volume: 138, Issue:10

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biphenyl Compounds; Diet; Drug Discovery; Eating; Exercise; Exercise Therapy; Humans; Hypoglycemic Agents; Isoenzymes; Metabolic Diseases; Metformin; Molecular Targeted Therapy; Muscle Contraction; Pyrones; Ribonucleosides; Thiophenes

2018
The treatment of iatrogenic male incontinence: latest results and future perspectives.
    Reviews on recent clinical trials, 2013, Volume: 8, Issue:1

    Topics: Antidepressive Agents; Behavior Therapy; Biofeedback, Psychology; Duloxetine Hydrochloride; Electric Stimulation Therapy; Equipment Design; Exercise Therapy; Humans; Iatrogenic Disease; Male; Muscle Contraction; Off-Label Use; Pelvic Floor; Prostatectomy; Stem Cells; Suburethral Slings; Thiophenes; Urinary Incontinence, Stress; Urinary Sphincter, Artificial

2013
Biologically active benzo [b]thiophene derivatives. II.
    Advances in drug research, 1977, Volume: 11

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Biogenic Amines; Biological Transport, Active; Central Nervous System; Diuretics; Enzyme Inhibitors; Female; Fertility; Hemodynamics; In Vitro Techniques; Intestinal Absorption; Male; Melanophores; Muscle Contraction; Muscle, Smooth; Pesticides; Platelet Aggregation; Protein Biosynthesis; Thiophenes

1977

Trials

1 trial(s) available for thiophenes and Muscle Contraction

ArticleYear
The effect of previous treatment experience and incontinence severity on the placebo response of stress urinary incontinence.
    American journal of obstetrics and gynecology, 2004, Volume: 191, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Muscle Contraction; Pelvic Floor; Placebo Effect; Randomized Controlled Trials as Topic; Retreatment; Thiophenes; Urinary Incontinence, Stress

2004

Other Studies

72 other study(ies) available for thiophenes and Muscle Contraction

ArticleYear
Gender-Related Differences of Tachykinin NK
    The Journal of pharmacology and experimental therapeutics, 2020, Volume: 375, Issue:1

    Topics: Colon; Dipeptides; Electric Stimulation; Female; Gene Expression; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurons; Peptide Fragments; Receptors, Neurokinin-2; Sex Characteristics; Signal Transduction; Thiophenes

2020
Stability of the acetic acid-induced bladder irritation model in alpha chloralose-anesthetized female cats.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Acetic Acid; Adrenergic Uptake Inhibitors; Anesthesia; Animals; Blood Pressure; Cats; Chloralose; Disease Models, Animal; Duloxetine Hydrochloride; Electromyography; Female; Heart Rate; Humans; Hypnotics and Sedatives; Muscle Contraction; Respiration; Thiophenes; Time Factors; Urethra; Urinary Bladder; Urinary Bladder Diseases; Urination

2013
N-acylhydrazone improves exercise intolerance in rats submitted to myocardial infarction by the recovery of calcium homeostasis in skeletal muscle.
    Life sciences, 2014, Jan-14, Volume: 94, Issue:1

    Topics: Animals; Caffeine; Calcium; Disease Models, Animal; Exercise Tolerance; Homeostasis; Hydrazones; Male; Muscle Contraction; Muscle Fatigue; Muscle, Skeletal; Myocardial Infarction; Physical Conditioning, Animal; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thiophenes; Time Factors

2014
Antagonist profile of ibodutant at the tachykinin NK(2) receptor in guinea pig isolated bronchi.
    European journal of pharmacology, 2013, Nov-15, Volume: 720, Issue:1-3

    Topics: Allergens; Animals; Bronchi; Bronchoconstriction; Dipeptides; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Receptors, Neurokinin-2; Thiophenes

2013
A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators.
    The Biochemical journal, 2014, Jun-15, Volume: 460, Issue:3

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Benzimidazoles; Biphenyl Compounds; Enzyme Activation; Fatty Acids; Glucose; Glycogen; Male; Mice; Muscle Contraction; Muscle, Skeletal; Pyrones; Rats; Ribonucleotides; Thiophenes

2014
EP2 and EP4 receptors mediate PGE2 induced relaxation in murine colonic circular muscle: pharmacological characterization.
    Pharmacological research, 2014, Volume: 90

    Topics: Alprostadil; Animals; Azetidines; Colon; Dinoprostone; Female; In Vitro Techniques; Male; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles

2014
Selective endothelin A receptor antagonism with sitaxentan reduces neointimal lesion size in a mouse model of intraluminal injury.
    British journal of pharmacology, 2015, Volume: 172, Issue:11

    Topics: Animals; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Femoral Artery; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth, Vascular; Myography; Neointima; Pyrrolidines; Thiophenes

2015
Inhibition of protein tyrosine phosphatases unmasks vasoconstriction and potentiates calcium signaling in rat aorta smooth muscle cells in response to an agonist of 5-HT2B receptors BW723C86.
    Biochemical and biophysical research communications, 2017, 01-29, Volume: 483, Issue:1

    Topics: Animals; Aorta; Calcium Signaling; Cell Separation; Indoles; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Oxidative Stress; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; RNA, Messenger; Serotonin 5-HT2 Receptor Agonists; Thiophenes; Vanadates; Vasoconstriction; Vasoconstrictor Agents

2017
AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:3

    Topics: Afferent Pathways; Animals; Benzamides; Female; Gene Expression; Muscle Contraction; Polymerase Chain Reaction; Pressoreceptors; Rats; Rats, Sprague-Dawley; Reflex; Thiophenes; TRPM Cation Channels; Urinary Bladder, Overactive

2008
The facilitatory effect of duloxetine combined with pelvic floor muscle training on the excitability of urethral sphincter motor neurons.
    International urogynecology journal and pelvic floor dysfunction, 2009, Volume: 20, Issue:6

    Topics: Adult; Combined Modality Therapy; Duloxetine Hydrochloride; Exercise Therapy; Female; Humans; Motor Neurons; Muscle Contraction; Pelvic Floor; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urethra; Urinary Incontinence, Stress; Urodynamics; Young Adult

2009
Pharmacological characterization of (3-thienylidene)-3,4-methylenedioxybenzoylhydrazide: a novel muscarinic agonist with antihypertensive profile.
    American journal of hypertension, 2010, Volume: 23, Issue:2

    Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Benzodioxoles; Blood Pressure; Cyclic GMP; Hypertension; In Vitro Techniques; Injections, Intravenous; Male; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Muscarinic; Thiophenes; Vasodilation

2010
Structure-activity relationships of 6-methyl-benzo[b]thiophene-2-carboxylic acid (1-[(S)-1-benzyl-4-[4-(tetrahydropyran-4-ylmethyl)piperazin-1-yl]butylcarbamoyl]cyclopentyl)amide, potent antagonist of the neurokinin-2 receptor.
    Journal of medicinal chemistry, 2010, May-27, Volume: 53, Issue:10

    Topics: Amides; Animals; Colon; Furans; Guinea Pigs; Humans; In Vitro Techniques; Intestinal Absorption; Male; Molecular Conformation; Muscle Contraction; Muscle, Smooth; Piperazines; Radioligand Assay; Receptors, Neurokinin-2; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Urinary Bladder

2010
Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoids.
    Peptides, 2011, Volume: 32, Issue:2

    Topics: Animals; Atropine; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastrointestinal Motility; Gastrointestinal Transit; Guinea Pigs; Ileum; Lower Gastrointestinal Tract; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Oligopeptides; Piperidines; Piroxicam; Prostaglandins; Quinuclidines; Tetrodotoxin; Thiophenes; Upper Gastrointestinal Tract

2011
Ticagrelor, but not clopidogrel and prasugrel, prevents ADP-induced vascular smooth muscle cell contraction: a placebo-controlled study in rats.
    Thrombosis research, 2012, Volume: 130, Issue:1

    Topics: Adenosine; Adenosine Diphosphate; Animals; Arteries; Clopidogrel; Muscle Contraction; Myocytes, Smooth Muscle; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Rats; Rats, Wistar; Thiophenes; Ticagrelor; Ticlopidine

2012
First-in-class, dual-action, 3,5-disubstituted indole derivatives having human nitric oxide synthase (nNOS) and norepinephrine reuptake inhibitory (NERI) activity for the treatment of neuropathic pain.
    Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Analgesics; Animals; CHO Cells; Coronary Vessels; Cricetinae; Cricetulus; Cyclohexanes; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; HEK293 Cells; High-Throughput Screening Assays; Humans; In Vitro Techniques; Indoles; Muscle Contraction; Muscle, Smooth, Vascular; Neuralgia; Nitric Oxide Synthase Type I; Norepinephrine Plasma Membrane Transport Proteins; Rats; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Vascular Resistance

2012
BENZO(B)THIOPHENE DERIVATIVES. IV. THE PREPARATION AND PHARMACOLOGICAL ACTIVITY OF COMPOUNDS RELATED TO SEROTONIN AND GRAMINE.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Alkaloids; Blood Pressure; Cats; Chemistry, Pharmaceutical; Female; Guinea Pigs; Humans; Ileum; Indole Alkaloids; Jejunum; Mice; Muscle Contraction; Muscle, Smooth; Muscles; Pharmacology; Rats; Research; Serotonin; Stomach; Thiophenes; Toxicology; Uterus; Vasomotor System

1963
Antinociceptive properties of acetylenic thiophene and furan derivatives: evidence for the mechanism of action.
    Life sciences, 2005, Mar-25, Volume: 76, Issue:19

    Topics: Acetic Acid; Acetylene; Analgesics; Animals; Capsaicin; Dopamine Agents; Exploratory Behavior; Furans; Hot Temperature; Immersion; Male; Mice; Motor Activity; Muscarinic Antagonists; Muscle Contraction; Narcotic Antagonists; Pain; Pain Measurement; Pharmaceutical Solutions; Reaction Time; Receptors, Muscarinic; Thiophenes

2005
Synthesis and vasodilatory activity of new N-acylhydrazone derivatives, designed as LASSBio-294 analogues.
    Bioorganic & medicinal chemistry, 2005, May-16, Volume: 13, Issue:10

    Topics: Animals; Aorta, Thoracic; Endothelium, Vascular; Heart Atria; Hydrazones; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Wistar; Thiophenes; Vasoconstriction; Vasodilation; Vasodilator Agents

2005
Facilitatory neuromodulative effect of duloxetine on pudendal motor neurons controlling the urethral pressure: a functional urodynamic study in healthy women.
    European urology, 2006, Volume: 50, Issue:1

    Topics: Blood Pressure; Duloxetine Hydrochloride; Female; Humans; Motor Neurons; Muscle Contraction; Pressure; Reference Values; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urethra

2006
Acute and long-term administration of citalopram desensitizes alpha2-adrenoceptors in the rat vas deferens.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Brimonidine Tartrate; Citalopram; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Vas Deferens

2006
MEN15596, a novel nonpeptide tachykinin NK2 receptor antagonist.
    European journal of pharmacology, 2006, Nov-07, Volume: 549, Issue:1-3

    Topics: Aged; Animals; Binding, Competitive; Bronchoconstriction; Cell Membrane; CHO Cells; Colon; Cricetinae; Cricetulus; Dipeptides; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; In Vitro Techniques; Male; Mice; Middle Aged; Muscle Contraction; Neurokinin A; Peptide Fragments; Rabbits; Radioligand Assay; Rats; Rats, Wistar; Receptors, Neurokinin-2; Swine; Thiophenes; Vasoconstriction

2006
Synthesis, affinity profile, and functional activity of muscarinic antagonists with a 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine structure.
    Journal of medicinal chemistry, 2007, Mar-22, Volume: 50, Issue:6

    Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Pyrrolidines; Rabbits; Radioligand Assay; Receptors, Muscarinic; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Vas Deferens

2007
Discovery of a new series of potent and selective linear tachykinin NK2 receptor antagonists.
    Journal of medicinal chemistry, 2007, Oct-04, Volume: 50, Issue:20

    Topics: Administration, Oral; Animals; Caco-2 Cells; Colon; Cyclopentanes; Dipeptides; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Injections; Intestinal Absorption; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Permeability; Piperidines; Pyrans; Radioligand Assay; Receptors, Neurokinin-2; Stereoisomerism; Thiophenes; Urinary Bladder

2007
Carbonic anhydrases IV and IX: subcellular localization and functional role in mouse skeletal muscle.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:2

    Topics: Animals; Carbonic Anhydrase IV; Carbonic Anhydrase IX; Carbonic Anhydrases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Mice; Mice, Knockout; Microscopy, Confocal; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Sarcolemma; Sarcoplasmic Reticulum; Sulfonamides; Thiophenes; Time Factors; Transport Vesicles

2008
alpha,alpha-Cyclopentaneglycine dipeptides capped with biaryls as tachykinin NK(2) receptor antagonists.
    ChemMedChem, 2008, Volume: 3, Issue:7

    Topics: Animals; Binding, Competitive; Biphenyl Compounds; Cell Membrane; Colon; Cyclopentanes; Dipeptides; Glycine; Guinea Pigs; Muscle Contraction; Receptors, Neurokinin-2; Thiophenes

2008
Synthesis of some 3-indenealkylamines. Comparison of the biological activity of 3-indenealkylamines and 3-benzo[b]thiophenealkylamines with their tryptamine isosteres.
    Journal of medicinal chemistry, 1967, Volume: 10, Issue:5

    Topics: Amides; Amines; Animals; Benzene Derivatives; Dopamine; Indenes; Muscle Contraction; Rats; Stomach; Thiophenes; Tryptamines

1967
Synthesis and pharmacological activity of benzo[b]thiophene-3-carboxylic acid derivatives.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:2

    Topics: Anesthetics, Local; Animals; Chemical Phenomena; Chemistry, Physical; Cornea; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Rabbits; Thiophenes

1983
Effects of cyproheptadine, ketotifen and sodium nitroprusside on mechanical activity and calcium uptake in guinea pig taenia coli in vitro.
    Respiration; international review of thoracic diseases, 1980, Volume: 39 Suppl 1

    Topics: Animals; Calcium; Colon; Cyproheptadine; Ferricyanides; Guinea Pigs; Ketotifen; Muscle Contraction; Nitroprusside; Piperidines; Thiophenes

1980
Effects of timepidium bromide, hyoscine-N-butylbromide and atropine on the isolated guinea pig gallbladder and sphincter of Oddi.
    Japanese journal of pharmacology, 1980, Volume: 30, Issue:3

    Topics: Acetylcholine; Ampulla of Vater; Animals; Atropine; Butylscopolammonium Bromide; Depression, Chemical; Electric Stimulation; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Norepinephrine; Parasympatholytics; Perfusion; Piperidines; Scopolamine Derivatives; Sphincter of Oddi; Thiophenes

1980
Enhancement of adenosine A1 receptor functions by benzoylthiophenes in guinea pig tissues in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:2

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Electric Stimulation; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Male; Muscle Contraction; Myocardial Contraction; Peptides; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Receptors, Purinergic P1; Ribonucleosides; Thienopyridines; Thiophenes; Wasp Venoms

1995
Effects of duloxetine, a combined serotonin and norepinephrine reuptake inhibitor, on central neural control of lower urinary tract function in the chloralose-anesthetized female cat.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:2

    Topics: Acetates; Acetic Acid; Adrenergic Uptake Inhibitors; Anesthesia; Animals; Brain; Chick Embryo; Chloralose; Duloxetine Hydrochloride; Electromyography; Ergolines; Female; Muscle Contraction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Bladder

1995
The action of 1,2,3,5,6,11b-hexahydro-[1]benzothieno [3,2-g]indolizine hydrochloride (ADT 16) on peripheral and central responses mediated by 5-hydroxytryptaminergic and adrenergic systems of the rat.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:10

    Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Guinea Pigs; In Vitro Techniques; Indolizines; Male; Mianserin; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth; Phenylephrine; Rats; Rats, Wistar; Reflex; Serotonin Antagonists; Stomach; Thiophenes; Vas Deferens

1994
Influence of age on control of norepinephrine release: Ca2+ channels and dopamine D2 receptors.
    European journal of pharmacology, 1994, Jan-24, Volume: 252, Issue:1

    Topics: Aging; Animals; Arteries; Calcium Channel Blockers; Calcium Channels; Dopamine Agents; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; omega-Conotoxin GVIA; Peptides; Rats; Rats, Inbred F344; Receptors, Dopamine D2; Sympathetic Nervous System; Tail; Tetrahydronaphthalenes; Thiophenes

1994
Reversal of in vitro lipopolysaccharide-induced suppression of contraction in rat aorta by NG-nitro-arginine, diphenyleneiodonium and di-2-thienyliodonium.
    European journal of pharmacology, 1996, Jan-18, Volume: 296, Issue:1

    Topics: Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Hypoglycemic Agents; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroarginine; Onium Compounds; Phenylephrine; Rats; Rats, Sprague-Dawley; Thiophenes

1996
Conformationally constrained butyrophenones with mixed dopaminergic (D(2)) and serotoninergic (5-HT(2A), 5-HT(2C)) affinities: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and -thienocycloalkanones as putative atypical an
    Journal of medicinal chemistry, 1999, Jul-29, Volume: 42, Issue:15

    Topics: Animals; Antipsychotic Agents; Aorta, Thoracic; Brain; Catalepsy; Cattle; Dopamine Agents; In Vitro Techniques; Isoxazoles; Male; Mice; Models, Molecular; Motor Activity; Muscle Contraction; Muscle, Smooth, Vascular; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Agents; Structure-Activity Relationship; Thiophenes

1999
The effects of the carbonic anhydrase inhibitors methazolamide, diclofenamide and dorzolamide on trabecular meshwork and ciliary muscle contractility.
    Experimental eye research, 1999, Volume: 69, Issue:4

    Topics: Animals; Carbonic Anhydrase Inhibitors; Cattle; Ciliary Body; Dichlorphenamide; Methazolamide; Muscle Contraction; Sulfonamides; Thiophenes; Trabecular Meshwork

1999
A novel thienylhydrazone, (2-thienylidene)3,4-methylenedioxybenzoylhydrazine, increases inotropism and decreases fatigue of skeletal muscle.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Action Potentials; Animals; Cardiotonic Agents; Electric Stimulation; Hydrazones; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle Fatigue; Muscle Fibers, Skeletal; Muscle, Skeletal; Myocardial Contraction; Rana pipiens; Thiophenes

2001
General pharmacological profile of the novel muscarinic receptor agonist SNI-2011, a drug for xerostomia in Sjögren's syndrome. 2nd communication: effects on somatic nervous system and on autonomic nervous system and smooth muscle.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:2

    Topics: Anesthetics; Animals; Autonomic Nervous System; Catecholamines; Cats; Guinea Pigs; Histamine Antagonists; Male; Mice; Mice, Inbred ICR; Muscarinic Agonists; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Muscle, Smooth, Vascular; Neuromuscular Junction; Nictitating Membrane; Peripheral Nervous System; Pupil; Quinuclidines; Rabbits; Rats; Rats, Inbred F344; Rats, Wistar; Sjogren's Syndrome; Thiophenes; Xerostomia

2002
Synthesis and spasmolytic action of 2-substituted thienopyrimidin-4-one derivatives.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:5

    Topics: Animals; Calcium Channels, L-Type; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Thiophenes

2002
Inhibition by suprofen and other non-narcotic analgesic drugs of the effects of prostaglandin precursor on isolated tissues and platelets.
    Archives internationales de pharmacodynamie et de therapie, 1976, Volume: 220, Issue:2

    Topics: Analgesics; Animals; Arachidonic Acids; Autacoids; Blood Platelets; Guinea Pigs; In Vitro Techniques; Male; Malondialdehyde; Muscle Contraction; Muscle, Smooth; Peroxides; Phenylpropionates; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Thiophenes

1976
Antagonism of arachidonic acid hydroperoxide on isolated gastrointestinal tissues as a measure of the inhibition of prostaglandin biosynthesis.
    Advances in prostaglandin and thromboxane research, 1976, Volume: 1

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Biological Assay; Bradykinin; Depression, Chemical; Dose-Response Relationship, Drug; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Peroxides; Phenylbutazone; Phenylpropionates; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Serotonin Antagonists; Thiophenes

1976
[Antihistaminic activity of tiemonium methylsulfate on isolated guinea pig ileum and trachea].
    Bollettino chimico farmaceutico, 1978, Volume: 117, Issue:11

    Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Morpholines; Muscle Contraction; Receptors, Histamine; Thiophenes; Trachea

1978
[Strict additivity of the antispasmodic effects of papaverine and tiemonium: an example of sequential blockage].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1977, Volume: 171, Issue:4

    Topics: Acetylcholine; Animals; Barium; Female; Guinea Pigs; Histamine Antagonists; Ileum; Jejunum; Kinetics; Male; Morpholines; Muscle Contraction; Papaverine; Parasympatholytics; Rats; Thiophenes

1977
Pharmacological findings on cetiedil.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:12

    Topics: Animals; Autonomic Nervous System; Azepines; Dogs; Electrocardiography; Guinea Pigs; Hemodynamics; Humans; In Vitro Techniques; Kinetics; Mice; Microcirculation; Muscle Contraction; Parasympatholytics; Phosphodiesterase Inhibitors; Platelet Aggregation; Rabbits; Thiophenes; Vasodilator Agents

1978
[Pharmacological studies of the action of cetiedile on smooth muscle].
    Bollettino della Societa italiana di biologia sperimentale, 1978, Feb-15, Volume: 54, Issue:3

    Topics: Animals; Azepines; Blood Vessels; Guinea Pigs; Ileum; Intestine, Large; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Thiophenes; Vasodilator Agents

1978
[Pharmacological actions of timepidium bromide on the motility of visceral smooth muscles and the secretion of digestive juice in experimental animals (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1978, Volume: 74, Issue:5

    Topics: Animals; Atropine; Bethanechol Compounds; Bile; Blood Pressure; Butylscopolammonium Bromide; Cats; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Female; Gallbladder; Gastric Juice; Gastrointestinal Motility; Male; Mice; Muscle Contraction; Muscle, Smooth; Mydriatics; Pancreatic Juice; Piperidines; Rats; Salivation; Thiophenes; Uterine Contraction

1978
[The pharmacology of some 1,3-dioxolanes, 1,3-oxathiolanes and 1,3-dithiolanes].
    Die Pharmazie, 1976, Volume: 31, Issue:5

    Topics: Animals; Anticonvulsants; Cats; Dioxolanes; Dioxoles; Guinea Pigs; Heterocyclic Compounds; Hexobarbital; In Vitro Techniques; Lethal Dose 50; Mice; Motor Activity; Muscle Contraction; Rats; Reflex; Sleep; Thiophenes; Time Factors

1976
Synthesis of alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid, suprofen, and derivatives.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:10

    Topics: Acetates; Animals; Arachidonic Acids; Drug Evaluation, Preclinical; Methods; Muscle Contraction; Phenylpropionates; Prostaglandin Antagonists; Rats; Spasm; Structure-Activity Relationship; Thiophenes

1975
Suprofen, a potent antagonist of acetic acid-induced writhing in rats.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:10

    Topics: Acetates; Analgesics; Animals; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Indomethacin; Ketoprofen; Male; Muscle Contraction; Phenylacetates; Phenylbutazone; Phenylpropionates; Prostaglandin Antagonists; Prostaglandins; Rats; Spasm; Thiophenes; Tolmetin

1975
Complex prejunctional actions of the D2 dopamine agonists N-0923 and N-0924 in the rat tail artery.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Animals; Calcium; Dopamine Agents; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Perfusion; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Tail; Tetrahydronaphthalenes; Thiophenes

1992
Interaction of tertatolol at the "atypical" or beta 3-adrenoceptor in guinea-pig ileum.
    General pharmacology, 1992, Volume: 23, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Electric Stimulation; Ethanolamines; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Male; Methiothepin; Muscle Contraction; Muscle, Smooth; Propanolamines; Receptors, Adrenergic, beta; Thiophenes

1992
Effects of tertatolol on the responsiveness of isolated femoral, mesenteric, and renal resistance arteries to adrenergic stimuli.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Arteries; Femoral Artery; In Vitro Techniques; Isomerism; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Propanolamines; Propranolol; Rats; Rats, Inbred WKY; Renal Artery; Sympathetic Nervous System; Thiophenes

1990
Pharmacological studies on novel muscarinic agonists, 1-oxa-8-azaspiro[4.5]decane derivatives, YM796 and YM954.
    European journal of pharmacology, 1990, Oct-23, Volume: 187, Issue:3

    Topics: Animals; Avoidance Learning; Hippocampus; Hydrolysis; Hypothermia; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Phosphatidylinositols; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Spiro Compounds; Succinimides; Thiophenes; Tremor

1990
Prejunctional adrenoceptor activity of N-0437: a relatively selective DA2 dopamine receptor agonist.
    European journal of pharmacology, 1990, Mar-27, Volume: 178, Issue:3

    Topics: Animals; Cats; Domperidone; Dopamine Agents; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Naphthalenes; Nictitating Membrane; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Dopamine D1; Stereoisomerism; Tetrahydronaphthalenes; Thiophenes; Yohimbine

1990
Characterization of kappa-opioid receptors in the guinea-pig ileum.
    European journal of pharmacology, 1990, Jun-21, Volume: 182, Issue:1

    Topics: Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth; Naloxone; Pyrroles; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes

1990
Synthesis and pharmacological activity of 2-alkylthio substituted thieno[2,3-d]pyrimidine-4-one and 5H-pyrimido [5,4-b]indol-4-one.
    Die Pharmazie, 1990, Volume: 45, Issue:7

    Topics: Animals; Aorta, Thoracic; Charcoal; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Male; Mice; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Parasympatholytics; Pyrimidines; Pyrimidinones; Rabbits; Thiophenes

1990
Calcium channel antagonism by pizotifen.
    Journal of neurology, neurosurgery, and psychiatry, 1985, Volume: 48, Issue:4

    Topics: Animals; Basilar Artery; Calcium; Dogs; Dose-Response Relationship, Drug; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Pizotyline; Thiophenes

1985
PD117302: a selective agonist for the kappa-opioid receptor.
    British journal of pharmacology, 1988, Volume: 93, Issue:3

    Topics: Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Pyrroles; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes; Vas Deferens

1988
Chiral muscarinic agonists possessing a 1,3-oxathiolane nucleus: enantio- and tissue-selectivity on isolated preparations of guinea-pig ileum and atria and of rat urinary bladder.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:3

    Topics: Animals; Binding, Competitive; Carbachol; Guinea Pigs; Heart; Heterocyclic Compounds; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Receptors, Muscarinic; Stereoisomerism; Thiophenes; Urinary Bladder

1988
Enantioselectivity of muscarinic antagonists. 2,2-Dicyclohexyl-5-[(dimethylamino)methyl]-1,3-oxathiolane methiodides and related 3-oxides.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:9

    Topics: Animals; Atrial Function; Carbachol; Chemical Phenomena; Chemistry; Cyclohexanes; Guinea Pigs; Heart Rate; Heterocyclic Compounds; Ileum; Molecular Conformation; Muscarine; Muscle Contraction; Myocardial Contraction; Rats; Receptors, Muscarinic; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Urinary Bladder

1988
Enantioselectivity of muscarinic antagonists. Isomeric 2-cyclohexyl-2-phenyl-5-[(dimethylamino)methyl]-1,3-oxathiolane methiodides.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:9

    Topics: Animals; Atrial Function; Chemical Phenomena; Chemistry; Cyclohexanes; Guinea Pigs; Heart Rate; Heterocyclic Compounds; Ileum; Molecular Conformation; Muscarine; Muscle Contraction; Myocardial Contraction; Rats; Receptors, Muscarinic; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Urinary Bladder

1988
Resolution, absolute configuration, and cholinergic enantioselectivity of (+)- and (-)-cis-2-methyl-5-[(dimethylamino)methyl]-1,3-oxathiolane methiodide.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Animals; Anura; Dimethylamines; Guinea Pigs; Heterocyclic Compounds; Male; Muscarine; Muscle Contraction; Muscle, Smooth; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Stereoisomerism; Thiophenes

1986
[Effect of tiemonium iodide (Visceralgine) on the ureteral contractile activities and its clinical use in urology].
    Hinyokika kiyo. Acta urologica Japonica, 1970, Volume: 16, Issue:10

    Topics: Adult; Aged; Female; Hemorrhage; Humans; Injections, Intramuscular; Iodides; Male; Middle Aged; Morpholines; Muscle Contraction; Parasympatholytics; Prostatic Hyperplasia; Prostatic Neoplasms; Quaternary Ammonium Compounds; Thiophenes; Tuberculosis, Renal; Ureter; Urologic Diseases; Uterine Neoplasms

1970
N-substituted 2-amino-1-(2-thienyl)ethanols as beta-adrenergic blocking agents.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:8

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Ethanolamines; Guinea Pigs; Heart Rate; Histamine; Ileum; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Norepinephrine; Rats; Serotonin; Structure-Activity Relationship; Thiophenes; Vas Deferens

1973
Antagonism of the trypanocide, berenil, and the nematocide, morantel, by tubocurarine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 280, Issue:1

    Topics: Acetylcholine; Amidines; Animals; Antinematodal Agents; Anura; Glycine; Muscle Contraction; Pyrimidines; Thiophenes; Triazenes; Trypanocidal Agents; Tubocurarine

1973
Some pharmacological effects of the nematocide, morantel.
    British journal of pharmacology, 1973, Volume: 47, Issue:1

    Topics: Animals; Anthelmintics; Blood Pressure; Bufonidae; Cats; Chickens; Diaphragm; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Jejunum; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Nictitating Membrane; Phrenic Nerve; Pyrimidines; Rabbits; Rats; Sciatic Nerve; Succinylcholine; Synaptic Transmission; Thiophenes

1973
[The antagonism exercised by Sandomigran (BC 105) on some properties of bradykinin].
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 204, Issue:1

    Topics: Adrenal Medulla; Adrenalectomy; Animals; Atropine; Benzocycloheptenes; Blood Pressure; Bradykinin; Dose-Response Relationship, Drug; Guanethidine; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Norepinephrine; Peptidyl-Dipeptidase A; Piperidines; Rats; Receptors, Drug; Serotonin; Stimulation, Chemical; Thiophenes; Tyramine

1973
Pharmacological properties of a new anticholinergic agent, 1, 1-dimethyl-5-methoxy-3-(dithien-2-ylmethylene) piperidinium bromide (SA-504).
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:5

    Topics: Anesthetics, Local; Animals; Cardiovascular System; Cats; Depression, Chemical; Female; Ganglia, Autonomic; Gastric Juice; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Irritants; Male; Methemoglobin; Methyl Ethers; Mice; Muscle Contraction; Muscle, Smooth; Mydriatics; Parasympatholytics; Piperidines; Rats; Respiration; Salivation; Stomach Ulcer; Thiophenes

1972
The effects of a new phencyclidine derivative and diazepinone derivative on the electroencephalographic and behavioral responses in the cat.
    T.-I.-T. journal of life sciences, 1973, Volume: 3, Issue:1

    Topics: Anesthetics; Animals; Antidepressive Agents; Azepines; Behavior, Animal; Brain; Cats; Cyclohexanes; Electroencephalography; Ethylamines; Female; Fluorobenzenes; Heart Rate; Male; Muscle Contraction; Pyrazoles; Respiration; Seizures; Thiophenes; Tranquilizing Agents

1973
Analogs of bradykinin containing -2-thienyl-L-alanine.
    Journal of medicinal chemistry, 1971, Volume: 14, Issue:9

    Topics: Alanine; Animals; Blood Pressure; Bradykinin; Female; Ileum; Male; Muscle Contraction; Peptides; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiophenes; Uterus

1971
Comparative pharmacology of 5-hydroxytryptamine and tis benzofuran, benzo(b)thiophen, and indene isosteres.
    Journal of medicinal chemistry, 1971, Volume: 14, Issue:17

    Topics: Animals; Benzofurans; Binding Sites; Body Temperature; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indenes; Male; Muscle Contraction; Phenoxybenzamine; Receptors, Drug; Serotonin; Serotonin Antagonists; Stomach; Structure-Activity Relationship; Thiophenes

1971
17-(5-Substituted 2-thienyl) and 17-(5-substituted 2-thienylidene) derivatives of selected 17-keto steroids.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:1

    Topics: 17-Ketosteroids; Androstanes; Androsterone; Animals; Carcinoma, Squamous Cell; Cell Division; Culture Techniques; Dogs; Estrogens; Estrone; Female; Heart; Heart Atria; Humans; Ketones; Lithium; Magnetic Resonance Spectroscopy; Mice; Muscle Contraction; Rabbits; Stimulation, Chemical; Thiophenes; Uterus

1969