Page last updated: 2024-08-18

thiophenes and Malignant Melanoma

thiophenes has been researched along with Malignant Melanoma in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (14.81)	18.7374
1990's	3 (11.11)	18.2507
2000's	2 (7.41)	29.6817
2010's	11 (40.74)	24.3611
2020's	7 (25.93)	2.80

Authors

Authors	Studies
Chen, X; Kuang, X; Liang, L; Liu, H; Liu, J; Su, J; Xiang, M; Xie, Z; Zhao, S	1
Bertalot, G; Bonaldi, T; Bossi, D; Confalonieri, S; Cuomo, A; Giardina, G; Granieri, L; Lanfrancone, L; Marocchi, F; Melixetian, M; Mohammadi, N; Nicoli, P; Pisati, F	1
Flem-Karlsen, K; Flørenes, VA; Gullestad, HP; Haugen, MH; Hermann, R; McFadden, E; Mælandsmo, GM; Omar, N; Ryder, T; Øy, GF	1
Bacon, C; Bowron, A; Greystoke, A; Halford, S; Jenkinson, F; Keun, H; Leech, N; McNeillis, R; Petrides, G; Plummer, R; Siskos, A; Walton, J	1
Cullinane, C; Dreyer, J; Dutton-Regester, K; Emran, AA; Gallagher, S; Gunatilake, D; Hayward, NK; Hersey, P; McArthur, G; Pirozyan, M; Rizos, H; Tiffen, J; Tseng, HY	1
Eberle, J; Fechner, H; Sarif, Z; Tolksdorf, B	1
Berezovskaya, A; Etchin, J; He, S; Jing, CB; Kaufman, CK; Layden, HM; Look, AT; Mansour, MR; Martel, MW; Patton, EE; Rodig, SJ; Thurston, G; van Rooijen, E; Zimmerman, MW; Zon, LI	1
Bérubé, J; de la Fouchardière, A; Landreville, S; Piquet, L; Weidmann, C	1
Arulananda, S; Behren, A; Cebon, J; Dobrovic, A; Evangelista, M; Fairlie, WD; Gunasingh, G; Haass, NK; Harris, TJ; Herold, MJ; Hobbs, C; John, T; Lee, EF; Mariadason, JM; Ramnac, C; Rohrbeck, L; Segal, D; Strasser, A; Tran, S; Zhu, H	1
Bhatnagar, A; Billeter, AT; Hellmann, JL; Polk, HC	1
Chreifi, G; Huang, H; Li, H; Martásek, P; Meyskens, FL; Poulos, TL; Roman, LJ; Silverman, RB; Yang, S	1
Altevogt, P; Arnold, A; Cerwenka, A; Fiegler, N; Moldenhauer, G; Paschen, A; Rose-John, S; Schlecker, E; Sucker, A; Textor, S; von Strandmann, EP	1
Aplin, AE; Vu, HL	1
Appelqvist, H; Cieślar-Pobuda, A; Jonasson, J; Kågedal, B; Karlsson, T; Magnusson, K; Nilsson, KP; Wigenius, J; Łos, MJ	1
Emilsen, E; Engesæter, B; Fjær, R; Flørenes, VA; Giller Fleten, K; Magnussen, GI; Nähse-Kumpf, V; Slipicevic, A	1
Cao, HH; Chen, YJ; Cheng, BC; Fong, WF; Fu, XQ; Guo, H; Kwan, HY; Lee, SK; Li, T; Su, T; Tse, AK; Yu, ZL; Zhu, PL	1
LaCasse, A; Schneider, J	1
Baldi, A; Citro, G; Fanciulli, M; Spugnini, EP	1
Davies, L; Marais, R; Ménard, D; Niculescu-Duvaz, D; Niculescu-Duvaz, I; Pons, JF; Springer, CJ; Suijkerbuijk, BM; Whittaker, S; Zambon, A	1
Critchley-Thorne, RJ; Holmes, SP; Lee, PP; Nacu, S; Weber, J; Yan, N	1
Bando, H; Tsubura, E; Yamashita, T	1
Ishihara, M; Kinjo, M; Kohga, S; Ogawa, H; Tanaka, K; Tanaka, N	1
Chen, LB; Garlid, KD; Hu, J; Song, K; Sun, X; Wong, JR	1
McCann, PP; Rasmussen, HS	1
Blanton, CD; Koebel, RF; Needham, LL	1
Kerbel, RS; Maamer, M; McIntire, LV; Menter, DG; Nicolson, GL; Patton, JT; Updyke, TV	1
Hansen, HH; Muggia, FM; Selawry, OS	1

Reviews

3 review(s) available for thiophenes and Malignant Melanoma

Article	Year
Transient receptor potential ion channels: powerful regulators of cell function. Annals of surgery, 2014, Volume: 259, Issue:2 Topics: Analgesics; Anti-Inflammatory Agents; Biomarkers; Calcium Channels; Capsaicin; Chronic Pain; Duloxetine Hydrochloride; Humans; Inflammation; Macrophages; Melanoma; Monocytes; Nerve Tissue Proteins; Pain, Postoperative; Respiratory Tract Diseases; Surgical Wound Infection; Thiophenes; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels	2014
Preclinical models in electrochemotherapy: the role of veterinary patients. Future oncology (London, England), 2012, Volume: 8, Issue:7 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Cat Diseases; Cats; Cisplatin; Dog Diseases; Dogs; Drug Evaluation, Preclinical; Electrochemotherapy; Epirubicin; Head and Neck Neoplasms; Melanoma; Mitoxantrone; Neoplasms; Quinazolines; Sarcoma; Thiophenes	2012
Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat. Pharmacology & therapeutics, 1997, Volume: 75, Issue:1 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Colorectal Neoplasms; Enzyme Inhibitors; Female; Hemangioma; Humans; Hydroxamic Acids; Melanoma; Metalloendopeptidases; Mice; Ovarian Neoplasms; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Skin Neoplasms; Thiophenes	1997

Trials

1 trial(s) available for thiophenes and Malignant Melanoma

Article	Year
Clinical studies with a new podophyllotoxin derivative, epipodophyllotoxin, 4'-demethyl-9-(4,6-O-2-thenylidine- -D-glucopyranoside) (NSC-122819). Cancer chemotherapy reports, 1971, Volume: 55, Issue:5 Topics: Aged; Antineoplastic Agents; Astrocytoma; Clinical Trials as Topic; Esophageal Neoplasms; Evaluation Studies as Topic; Fibroblasts; Glycosides; Humans; Hypotension; Lactones; Leiomyosarcoma; Leukopenia; Liver Neoplasms; Lung Neoplasms; Melanoma; Middle Aged; Mitosis; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllum; Structure-Activity Relationship; Thiophenes; Thrombocytopenia	1971

Article

Year

Clinical studies with a new podophyllotoxin derivative, epipodophyllotoxin, 4'-demethyl-9-(4,6-O-2-thenylidine- -D-glucopyranoside) (NSC-122819).

Cancer chemotherapy reports, 1971, Volume: 55, Issue:5

Topics: Aged; Antineoplastic Agents; Astrocytoma; Clinical Trials as Topic; Esophageal Neoplasms; Evaluation Studies as Topic; Fibroblasts; Glycosides; Humans; Hypotension; Lactones; Leiomyosarcoma; Leukopenia; Liver Neoplasms; Lung Neoplasms; Melanoma; Middle Aged; Mitosis; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllum; Structure-Activity Relationship; Thiophenes; Thrombocytopenia

1971

Other Studies

23 other study(ies) available for thiophenes and Malignant Melanoma

Article	Year
Pharmacological inhibition of USP7 suppresses growth and metastasis of melanoma cells in vitro and in vivo. Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:19 Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disease Models, Animal; DNA Damage; Humans; Immunohistochemistry; Melanoma; Melanoma, Experimental; Mice; Reactive Oxygen Species; Thiophenes; Ubiquitin-Specific Peptidase 7	2021
Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors. Cell reports, 2022, 09-20, Volume: 40, Issue:12 Topics: Cell Line, Tumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Demethylases; Humans; Melanoma; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins B-raf; Thiophenes; Ubiquitin-Specific Peptidase 7; Ubiquitins	2022
Targeting AXL and the DNA Damage Response Pathway as a Novel Therapeutic Strategy in Melanoma. Molecular cancer therapeutics, 2020, Volume: 19, Issue:3 Topics: Animals; Apoptosis; Axl Receptor Tyrosine Kinase; Biomarkers, Tumor; Cell Cycle Checkpoints; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Melanoma; Mice; Mice, Nude; Neoplasm Invasiveness; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; RNA, Small Interfering; Thiophenes; Tumor Cells, Cultured; Urea; Xenograft Model Antitumor Assays	2020
A case of malignant hyperlactaemic acidosis appearing upon treatment with the mono-carboxylase transporter 1 inhibitor AZD3965. British journal of cancer, 2020, Volume: 122, Issue:8 Topics: Acidosis, Lactic; Humans; Hyperlactatemia; Male; Melanoma; Middle Aged; Monocarboxylic Acid Transporters; Positron-Emission Tomography; Pyrimidinones; Symporters; Thiophenes	2020
Co-targeting bromodomain and extra-terminal proteins and MCL1 induces synergistic cell death in melanoma. International journal of cancer, 2020, 10-15, Volume: 147, Issue:8 Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Death; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Humans; Male; Melanoma; Mice; Mice, Inbred NOD; Mice, SCID; Myeloid Cell Leukemia Sequence 1 Protein; Proteins; Pyrimidines; Thiophenes; Up-Regulation	2020
Mcl-1 targeting strategies unlock the proapoptotic potential of TRAIL in melanoma cells. Molecular carcinogenesis, 2020, Volume: 59, Issue:11 Topics: Apoptosis; Biomarkers, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Melanoma; MicroRNAs; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; RNA, Small Interfering; Thiophenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured	2020
Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss. Oncogene, 2021, Volume: 40, Issue:38 Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Everolimus; Humans; Loss of Function Mutation; Melanoma; MTOR Inhibitors; Myeloid Cell Leukemia Sequence 1 Protein; Neurofibromin 1; Proto-Oncogene Proteins c-bcl-2; PTEN Phosphohydrolase; Pyrimidines; Sirolimus; Sulfonamides; Thiophenes; Xenograft Model Antitumor Assays; Zebrafish	2021
Expression of the serotonin receptor 2B in uveal melanoma and effects of an antagonist on cell lines. Clinical & experimental metastasis, 2018, Volume: 35, Issue:3 Topics: Adult; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Female; Gene Expression Profiling; Histones; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Phosphorylation; Protein Kinases; Pyrimidines; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; STAT5 Transcription Factor; Thiophenes; Uveal Neoplasms	2018
BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival. Cell death & disease, 2019, 04-24, Volume: 10, Issue:5 Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; bcl-X Protein; Bortezomib; Cell Line, Tumor; Cell Survival; Humans; Melanoma; Myeloid Cell Leukemia Sequence 1 Protein; Pyrimidines; Sulfonamides; Thiophenes	2019
Potent and selective double-headed thiophene-2-carboximidamide inhibitors of neuronal nitric oxide synthase for the treatment of melanoma. Journal of medicinal chemistry, 2014, Feb-13, Volume: 57, Issue:3 Topics: Amidines; Aniline Compounds; Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Isoenzymes; Melanoma; Mice; Models, Molecular; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Structure-Activity Relationship; Thiophenes	2014
Metalloprotease-mediated tumor cell shedding of B7-H6, the ligand of the natural killer cell-activating receptor NKp30. Cancer research, 2014, Jul-01, Volume: 74, Issue:13 Topics: ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Amyloid Precursor Protein Secretases; B7 Antigens; Cell Line, Tumor; Dipeptides; HCT116 Cells; HeLa Cells; Humans; Hydroxamic Acids; Killer Cells, Natural; Lymphocyte Activation; MCF-7 Cells; Melanoma; Membrane Proteins; Natural Cytotoxicity Triggering Receptor 3; Phenylalanine; Protease Inhibitors; RNA Interference; RNA, Messenger; RNA, Small Interfering; Thiophenes; Tumor Escape; Up-Regulation	2014
Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma. Molecular cancer research : MCR, 2014, Volume: 12, Issue:10 Topics: Apoptosis; Benzimidazoles; Cell Line, Tumor; Cell Movement; Drug Resistance, Neoplasm; Gene Knockdown Techniques; GTP Phosphohydrolases; Humans; Melanoma; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Molecular Targeted Therapy; Mutation; Neoplasm Invasiveness; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Skin Neoplasms; Thiophenes	2014
Differential vital staining of normal fibroblasts and melanoma cells by an anionic conjugated polyelectrolyte. Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2015, Volume: 87, Issue:3 Topics: Acetic Acid; Cell Line, Transformed; Fibroblasts; HeLa Cells; Humans; Melanoma; Molecular Probes; Polymers; Staining and Labeling; Thiophenes	2015
Combined inhibition of the cell cycle related proteins Wee1 and Chk1/2 induces synergistic anti-cancer effect in melanoma. BMC cancer, 2015, Jun-10, Volume: 15 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 2; Drug Synergism; Humans; Melanoma; Melanoma, Cutaneous Malignant; Mice; Nuclear Proteins; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Pyrimidinones; Skin Neoplasms; Thiophenes; Urea; Xenograft Model Antitumor Assays	2015
Sensitization of melanoma cells to alkylating agent-induced DNA damage and cell death via orchestrating oxidative stress and IKKβ inhibition. Redox biology, 2017, Volume: 11 Topics: Alkylating Agents; Animals; Cell Death; Cell Line, Tumor; DNA Damage; Humans; I-kappa B Kinase; Melanoma; Mice; Neoplasm Metastasis; Nitrosourea Compounds; Oxidative Stress; Thiophenes; Xenograft Model Antitumor Assays	2017
What is your diagnosis? Tinea nigra. Cutis, 2009, Volume: 84, Issue:6 Topics: Adult; Antifungal Agents; Diagnosis, Differential; Female; Humans; Imidazoles; Melanoma; Melanosis; Skin Neoplasms; Thiophenes; Tinea Pedis; Toes	2009
Potent BRAF kinase inhibitors based on 2,4,5-trisubstituted imidazole with naphthyl and benzothiophene 4-substituents. Bioorganic & medicinal chemistry, 2013, Mar-01, Volume: 21, Issue:5 Topics: Benzofurans; Cell Line, Tumor; Cell Survival; Humans; Imidazoles; Melanoma; Naphthols; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Structure-Activity Relationship; Thiophenes	2013
Down-regulation of the interferon signaling pathway in T lymphocytes from patients with metastatic melanoma. PLoS medicine, 2007, Volume: 4, Issue:5 Topics: Antigens, CD; Biomarkers; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Survival; Down-Regulation; Furans; Humans; Immunologic Factors; Immunotherapy; In Vitro Techniques; Interferon-alpha; Killer Cells, Natural; Melanoma; Oligonucleotide Array Sequence Analysis; Phosphorylation; Signal Transduction; Skin Neoplasms; STAT1 Transcription Factor; Thiophenes; Tyrosine	2007
Effects of antiplatelet agents on pulmonary metastases. Gan, 1984, Volume: 75, Issue:3 Topics: Adenosine Diphosphate; Animals; Depression, Chemical; Diltiazem; Dipyridamole; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Platelet Aggregation; Thiophenes; Ticlopidine; Trapidil	1984
Effects of 5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride (Ticlopidine), a platelet aggregation inhibitor, on blood-borne metastasis. Cancer research, 1981, Volume: 41, Issue:11 Pt 1 Topics: Animals; Cell Line; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplastic Cells, Circulating; Platelet Aggregation; Pyridines; Rats; Thiophenes; Ticlopidine	1981
AA1, a newly synthesized monovalent lipophilic cation, expresses potent in vivo antitumor activity. Cancer research, 1994, Mar-15, Volume: 54, Issue:6 Topics: Adenocarcinoma; Adenosine Triphosphate; Aniline Compounds; Animals; Antineoplastic Agents; Chlorocebus aethiops; Colonic Neoplasms; Disease Models, Animal; Epithelium; Female; Humans; Hydrolysis; Male; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Nude; Mitochondria, Liver; Models, Biological; Neoplasm Transplantation; Ovarian Neoplasms; Oxygen Consumption; Thiophenes; Transplantation, Heterologous; Tumor Cells, Cultured; Urinary Bladder Neoplasms	1994
Synthesis of thieno[2,3-b]azepin-4-ones as potential antineoplastic agents. Journal of medicinal chemistry, 1975, Volume: 18, Issue:2 Topics: Animals; Antineoplastic Agents; Azepines; Leukemia L1210; Lymphoma; Melanoma; Mice; Neoplasms, Experimental; Thiophenes	1975
Transglutaminase stabilizes melanoma adhesion under laminar flow. Cell biophysics, 1991, Volume: 18, Issue:2 Topics: Aged; Antineoplastic Agents; Autoradiography; Cadaverine; Cell Adhesion; Cell Death; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fibronectins; Humans; Iodine Radioisotopes; Male; Melanoma; Stress, Mechanical; Thiophenes; Transglutaminases; Tumor Cells, Cultured	1991