Page last updated: 2024-08-18

thiophenes and MPTP Neurotoxicity Syndrome

thiophenes has been researched along with MPTP Neurotoxicity Syndrome in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
He, J; Tian, JW; Yao, JY; Yu, X1
Ago, Y; Kawasaki, T; Kitao, T; Matsuda, T; Nashida, T; Takagi, A; Takuma, K1
Iravani, MM; Jackson, MJ; Jenner, P; Olanow, CW; Rose, S; Scheller, D; Smith, LA; Stockwell, KA; Tayarani-Binazir, K1
Iravani, MM; Jackson, MJ; Jenner, P; Rose, S; Scheller, DK; Smith, LA; Stockwell, KA1
Bezard, E; Chan, P; Crossman, AR; Guan, L; Guigoni, C; Hill, M; Li, Q; Ravenscroft, P; Scheller, D; Wu, T; Zhang, R1
Breidenbach, A; Jackson, M; Jenner, P; Rose, S; Scheller, DK; Smith, L; Stockwell, K1
Domino, EF; Ni, L1
Andreassen, OA; Beal, MF; Ferrante, RJ; Klivenyi, P; Lancelot, E; Reif, D1

Other Studies

8 other study(ies) available for thiophenes and MPTP Neurotoxicity Syndrome

ArticleYear
Protection of MPTP-induced neuroinflammation and neurodegeneration by rotigotine-loaded microspheres.
    Life sciences, 2015, Mar-01, Volume: 124

    Topics: Animals; Antioxidants; Blotting, Western; Corpus Striatum; Cytokines; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Microspheres; MPTP Poisoning; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Tetrahydronaphthalenes; Thiophenes

2015
A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl} azetidin-3-ol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice.
    Neuropharmacology, 2008, Volume: 55, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Brain; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Lipid Peroxidation; Male; Maleates; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; Neuroprotective Agents; Rotarod Performance Test; Thiophenes

2008
Continuous administration of rotigotine to MPTP-treated common marmosets enhances anti-parkinsonian activity and reduces dyskinesia induction.
    Experimental neurology, 2009, Volume: 219, Issue:2

    Topics: Analysis of Variance; Animals; Antiparkinson Agents; Callithrix; Disease Models, Animal; Drug Administration Schedule; Drug Delivery Systems; Dyskinesia, Drug-Induced; Female; Levodopa; Male; Motor Activity; Motor Skills; MPTP Poisoning; Tetrahydronaphthalenes; Thiophenes

2009
Continuous rotigotine administration reduces dyskinesia resulting from pulsatile treatment with rotigotine or L-DOPA in MPTP-treated common marmosets.
    Experimental neurology, 2010, Volume: 221, Issue:1

    Topics: Animals; Callithrix; Disability Evaluation; Disease Models, Animal; Dopamine Agents; Drug Administration Schedule; Drug Delivery Systems; Dyskinesia, Drug-Induced; Female; Levodopa; Male; Motor Activity; MPTP Poisoning; Statistics, Nonparametric; Tetrahydronaphthalenes; Thiophenes; Time Factors

2010
Rotigotine treatment partially protects from MPTP toxicity in a progressive macaque model of Parkinson's disease.
    Experimental neurology, 2007, Volume: 203, Issue:2

    Topics: Animals; Autoradiography; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Female; Immunohistochemistry; Macaca fascicularis; MPTP Poisoning; Neostriatum; Organotechnetium Compounds; Parkinson Disease, Secondary; Radiopharmaceuticals; Tetrahydronaphthalenes; Thiophenes; Tomography, Emission-Computed, Single-Photon; Tropanes; Tyrosine 3-Monooxygenase

2007
Plasma levels of rotigotine and the reversal of motor deficits in MPTP-treated primates.
    Behavioural pharmacology, 2007, Volume: 18, Issue:2

    Topics: Animals; Callithrix; Dose-Response Relationship, Drug; Female; Hyperkinesis; Injections, Subcutaneous; Motor Activity; MPTP Poisoning; Stereotyped Behavior; Tetrahydronaphthalenes; Thiophenes

2007
Trihexyphenidyl interactions with the dopamine D1-selective receptor agonist SKF-82958 and the D2-selective receptor agonist N-0923 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced hemiparkinsonian monkeys.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:1

    Topics: Animals; Antiparkinson Agents; Benzazepines; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Synergism; Female; Macaca nemestrina; MPTP Poisoning; Parkinson Disease, Secondary; Receptors, Dopamine D1; Receptors, Dopamine D2; Tetrahydronaphthalenes; Thiophenes; Trihexyphenidyl

1998
Inhibition of neuronal nitric oxide synthase protects against MPTP toxicity.
    Neuroreport, 2000, Apr-27, Volume: 11, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoquinolines; Male; Mice; MPTP Poisoning; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Substantia Nigra; Tetrahydroisoquinolines; Thiophenes; Tyrosine 3-Monooxygenase

2000