thiophenes has been researched along with Liver Steatosis in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 13 (61.90) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Chen, X; Guo, L; Liu, K; Wang, F; Wang, Z; Wu, B; Xu, H; Yu, F; Zhang, T | 1 |
| Imai, J; Katagiri, H; Kawana, Y; Sawada, S; Yamada, T | 1 |
| Lin, J; Wang, SY | 1 |
| Kim, W; Kim, YJ | 1 |
| Boudaba, N; Foretz, M; Huet, C; Marion, A; Pierre, R; Viollet, B | 1 |
| Atsumi, T; Miyoshi, H; Nakamura, A; Takahashi, K; Takase, T; Yamamoto, C; Yamauchi, Y; Yokota, I | 1 |
| Hayashizaki, Y; Imamura, M; Kihara, R; Kobayashi, Y; Kurosaki, E; Li, Q; Noda, A; Sasamata, M; Shibasaki, M; Tahara, A; Takasu, T; Tomiyama, H; Yamajuku, D; Yokono, M | 2 |
| Chang, CP; Chao, YS; Chen, PH; Hsiao, WC; Hung, MS; Lin, Y; Shia, KS; Wang, YT; Wu, CH; Yeh, YN | 1 |
| Bhat, S; Greenwood, J; Harriman, G; Harwood, HJ; Huang, X; Kapeller, R; Paul, D; Saha, AK; Tong, L; Wang, R; Westlin, WF | 1 |
| Chang, MS; Cho, JY; Kim, BG; Kim, H; Kim, JH; Kim, SG; Kim, W; Kim, YJ; Lee, CK; Lee, J; Lee, JH; Lee, JS; Yeon, JE; Yi, S | 1 |
| Bae, EJ; Hwahng, SH; Ki, SH; Kim, HE; Kim, SG | 1 |
| Brooks, JS; Brooks, SC; Kim, SG; Lee, MG; Lee, WH | 1 |
| Chang, CP; Chao, YS; Hsiao, WC; Hsieh, WP; Hung, MS; Lin, Y; Shia, KS; Vijayakumar, RS; Yeh, YN | 1 |
| Ban, JO; Cho, MC; Hong, JT; Jeong, HS; Kang, JW; Kim, EJ; Kim, JW; Kim, MS; Lee, DH; Yang, Y; Yoon, DY | 1 |
| Eom, JS; Kim, SG; Kim, TH; Lee, CG; Lee, YS; Yang, YM | 1 |
| Akiba, Y; Matsumoto, T; Takahashi, K | 1 |
| Imaizumi, Y; Kasai, T; Sugimoto, T | 1 |
| Artigue, F; Buffet, C; Cassan, P; Flamenbaum, M; Garcia, V; Kemeny, JL | 1 |
| Chan, CT; Kramsch, DM; Wells, H | 1 |
| Grosso, B; Nyffeneger, G; Pistone, AM; Podestà , F; Raviolo, E; Testa, D; Toselli, P | 1 |
1 review(s) available for thiophenes and Liver Steatosis
| Article | Year |
|---|---|
Therapeutic potential of dithiolethiones for hepatic diseases.
Topics: Animals; CCAAT-Enhancer-Binding Protein-beta; Fatty Liver; Glutathione Transferase; Humans; Inactivation, Metabolic; Insulin Resistance; Liver; Liver Cirrhosis; Liver Diseases; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Protein Kinases; Pyrazines; Receptors, Aryl Hydrocarbon; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Thiones; Thiophenes; TOR Serine-Threonine Kinases | 2009 |
1 trial(s) available for thiophenes and Liver Steatosis
| Article | Year |
|---|---|
Randomised clinical trial: the efficacy and safety of oltipraz, a liver X receptor alpha-inhibitory dithiolethione in patients with non-alcoholic fatty liver disease.
Topics: Adult; Animals; Double-Blind Method; Fatty Liver; Female; Humans; Liver X Receptors; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Middle Aged; Non-alcoholic Fatty Liver Disease; Pyrazines; Thiones; Thiophenes; Treatment Outcome; Ultrasonography | 2017 |
19 other study(ies) available for thiophenes and Liver Steatosis
| Article | Year |
|---|---|
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding.
Topics: Animals; ARNTL Transcription Factors; Circadian Rhythm; Diacylglycerol O-Acyltransferase; Diet, High-Fat; Dietary Fats; Fatty Liver; Gene Expression Regulation; Homeostasis; Hyperlipidemias; Intestinal Mucosa; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nuclear Receptor Subfamily 1, Group D, Member 1; Obesity; Promoter Regions, Genetic; Protein Binding; Pyrrolidines; Signal Transduction; Thiophenes; Triglycerides | 2021 |
Sodium-Glucose Cotransporter 2 Inhibitor Improves Complications of Lipodystrophy: A Case Report.
Topics: Adult; Diabetes Mellitus; Fatty Liver; Glucosides; Glycated Hemoglobin; Humans; Insulin Resistance; Lipodystrophy; Male; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2017 |
Letter: the efficacy of oltipraz in patients with non-alcoholic fatty liver disease has not been confirmed.
Topics: Fatty Liver; Humans; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Pyrazines; Thiones; Thiophenes | 2017 |
Letter: the efficacy of oltipraz in patients with non-alcoholic fatty liver disease has not been confirmed-authors' reply.
Topics: Fatty Liver; Humans; Non-alcoholic Fatty Liver Disease; Pyrazines; Thiones; Thiophenes | 2017 |
AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Cells, Cultured; Down-Regulation; Enzyme Activation; Fatty Acids; Fatty Liver; Gene Expression Regulation; Hepatocytes; Humans; Lipogenesis; Liver; Male; Metformin; Mice, Knockout; Oxidation-Reduction; Protein Serine-Threonine Kinases; Pyrones; Ribonucleotides; Small Molecule Libraries; Thiophenes | 2018 |
Factors with remission of fatty liver in patients with type 2 diabetes treated with ipragliflozin.
Topics: Aged; Body Mass Index; Diabetes Mellitus, Type 2; Fatty Liver; Female; gamma-Glutamyltransferase; Glucosides; Humans; Male; Middle Aged; Remission Induction; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Treatment Outcome; Triglycerides; Waist Circumference | 2019 |
Effects of SGLT2 selective inhibitor ipragliflozin on hyperglycemia, hyperlipidemia, hepatic steatosis, oxidative stress, inflammation, and obesity in type 2 diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diet, High-Fat; Fatty Liver; Glucose Tolerance Test; Glucosides; Glycosuria; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Male; Mice; Obesity; Oxidative Stress; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2013 |
Effects of sodium-glucose cotransporter 2 selective inhibitor ipragliflozin on hyperglycaemia, oxidative stress, inflammation and liver injury in streptozotocin-induced type 1 diabetic rats.
Topics: Albuminuria; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fatty Liver; Glomerular Filtration Rate; Glucose Intolerance; Glucosides; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Inflammation; Kidney; Liver; Male; Oxidative Stress; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors; Streptozocin; Thiophenes | 2014 |
A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Anti-Obesity Agents; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eating; Energy Metabolism; Fatty Liver; Ion Channels; Lipolysis; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Thermogenesis; Thiophenes; Uncoupling Protein 1; Weight Loss | 2015 |
Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.
Topics: Acetyl-CoA Carboxylase; Animals; Dyslipidemias; Enzyme Inhibitors; Fatty Liver; Female; Hep G2 Cells; Humans; Insulin Resistance; Male; Molecular Docking Simulation; Obesity; Protein Multimerization; Pyrimidinones; Rats, Sprague-Dawley; Rats, Zucker; Structure-Activity Relationship; Thiophenes | 2016 |
Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Fatty Liver; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Orphan Nuclear Receptors; Pyrazines; Receptors, Cytoplasmic and Nuclear; Ribosomal Protein S6 Kinases, 70-kDa; Sterol Regulatory Element Binding Protein 1; Thiones; Thiophenes; Transcriptional Activation | 2009 |
Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors.
Topics: Animals; Blood Glucose; Energy Metabolism; Fatty Acids; Fatty Liver; Hypothermia; Male; Mice; Mice, Inbred C57BL; Obesity; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Thiophenes; Weight Gain | 2012 |
Antiobesity effects of a sulfur compound thiacremonone mediated via down-regulation of serum triglyceride and glucose levels and lipid accumulation in the liver of db/db mice.
Topics: 3T3-L1 Cells; Acetyl-CoA Carboxylase; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Fatty Acid Synthases; Fatty Liver; Garlic; Glucose; Glucose Transporter Type 4; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; PPAR gamma; Sulfur Compounds; Thiophenes; Triglycerides | 2012 |
An active metabolite of oltipraz (M2) increases mitochondrial fuel oxidation and inhibits lipogenesis in the liver by dually activating AMPK.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Diet, High-Fat; Enzyme Activation; Fatty Liver; Hep G2 Cells; Humans; Lipid Metabolism; Lipogenesis; Liver; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Mitochondria; Orphan Nuclear Receptors; Oxidation-Reduction; Oxidative Stress; Pyrazines; Sterol Regulatory Element Binding Protein 1; Thiones; Thiophenes | 2013 |
Effect of diisopropyl 1,3-dithiolan-2-ylidenemalonate on experimental fatty livers in chicks.
Topics: Animals; Aspartate Aminotransferases; Body Weight; Chickens; Dienestrol; Estradiol; Fatty Liver; Lipid Metabolism; Liver; Male; Organ Size; Poultry Diseases; Propylthiouracil; Thiophenes | 1984 |
Effect of diisopropyl 1,3-dithiol-2-ylidenemalonate (NKK-105) on fatty liver induced by carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Fatty Liver; Lipoproteins; Liver; Male; Malonates; Microsomes, Liver; Protein Biosynthesis; Rats; Thiophenes; Triglycerides | 1981 |
[Non-alcoholic steatohepatitis with cirrhosis after raltitrexed administration].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Disease Progression; Drug Monitoring; Fat Necrosis; Fatty Liver; Female; Humans; Liver Cirrhosis; Liver Function Tests; Middle Aged; Quinazolines; Rectal Neoplasms; Thiophenes; Thymidylate Synthase | 2001 |
Suppression of calcific fibrous-fatty plaque formation in rabbits by agents not affecting elevated serum cholesterol levels. The effect of thiophene compounds.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Calcium; Cholesterol; Diet, Atherogenic; Fatty Liver; Phosphorus; Rabbits; Thiophenes | 1978 |
[Cholestatic fatty liver of probably iatrogenic origin].
Topics: Anticoagulants; Cholestasis, Intrahepatic; Fatty Liver; Female; Humans; Iatrogenic Disease; Middle Aged; Thiophenes; Ticlopidine | 1986 |