thiophenes has been researched along with Liver Dysfunction in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (30.00) | 29.6817 |
| 2010's | 12 (40.00) | 24.3611 |
| 2020's | 6 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Markham, A | 1 |
| Kuter, DJ | 1 |
| Arscott, KA; Burt, DA; Cochrane, K; Fossler, MJ; Nafziger, AN; Skobieranda, F | 1 |
| Flamm, SL; Nilles, KM | 1 |
| Al-Samkari, H; Kuter, DJ; Virk, ZM | 1 |
| Lozano, ML | 1 |
| Isaji, S; Ito, T; Kato, H; Kuriyama, N; Matsuda, A; Mizuno, S; Sakurai, H; Usui, M | 1 |
| Shirley, M | 1 |
| Carmichael, SL; Forde, EE; Frelinger, AL; Michelson, AD; Smolensky Koganov, E | 1 |
| Weinberg, EM | 1 |
| Al-Samkari, H | 1 |
| Boekens, H; Braun, M; Cawello, W; Fichtner, A | 1 |
| Bajorek, B; Wang, Y | 1 |
| Curnow, J; Joseph, J; McLintock, C; McRae, S; Nandurkar, H; Tran, H; Wood, P; Young, L | 1 |
| de Knegt, RJ; Maan, R; Veldt, BJ | 1 |
| Acharya, N; Heinloth, AN; Kuritzky, L; Regev, A; Robinson, M; Strombom, I; Wernicke, JF; Wohlreich, MM | 1 |
| Acharya, N; D'Souza, DN; DiPietro, N; Gahimer, JL; Strombom, I; Uetrecht, JP; Wernicke, J | 1 |
| D'Souza, DN; Henck, JW; Knadler, MP; Murray, I; Pangallo, B; Uetrecht, JP; Wang, F; Wernicke, J | 1 |
| Ağackiran, Y; Naziroğlu, M; Ozden, A; Sirmali, R; Uz, E; Vural, H; Yesildağ, A; Yesildağ, M; Yilmaz, HR; Yilmaz, N | 1 |
| Demetter, P; Geurs, F; Knape, S; Ponette, J; Ponette, S; Vandewaeter, S | 1 |
| Brooks, JS; Brooks, SC; Kim, SG; Lee, MG; Lee, WH | 1 |
| Ernest, CS; Farid, NA; Li, YG; Payne, CD; Salazar, DE; Small, DS; Winters, KJ | 1 |
| Brown, KM; Chen, SW; D'Agati, VD; Kim, M; Lee, HT; Park, SW | 1 |
| Tripodi, A | 1 |
| Graff, J; Harder, S | 1 |
| TRUTSCHEL, W | 1 |
| Farombi, EO; Surh, YJ | 1 |
| Bas, O; Karaman, O; Mollaoglu, H; Nacar, A; Sahin, O; Songur, A; Yagmurca, M | 1 |
| McMurtry, RJ; Mitchell, JR | 1 |
| Morin, D; Renouard, A; Rocher, I; Tillement, JP; Urien, S | 1 |
15 review(s) available for thiophenes and Liver Dysfunction
| Article | Year |
|---|---|
Avatrombopag: A Review in Thrombocytopenia.
Topics: Adult; Animals; Chronic Disease; Humans; Liver Diseases; Purpura, Thrombocytopenic, Idiopathic; Receptors, Thrombopoietin; Thiazoles; Thiophenes; Thrombocytopenia | 2021 |
The structure, function, and clinical use of the thrombopoietin receptor agonist avatrombopag.
Topics: Anemia, Aplastic; Hepatitis C; Humans; Liver Diseases; Receptors, Thrombopoietin; Thiazoles; Thiophenes; Thrombopoietin | 2022 |
Thrombocytopenia in Chronic Liver Disease: New Management Strategies.
Topics: Chronic Disease; Cinnamates; Hemorrhage; Humans; Liver Diseases; Platelet Count; Platelet Transfusion; Receptors, Thrombopoietin; Risk Factors; Surgical Procedures, Operative; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoiesis | 2020 |
Avatrombopag for the management of thrombocytopenia in patients with chronic liver disease.
Topics: Adult; Chronic Disease; Humans; Liver Diseases; Thiazoles; Thiophenes; Thrombocytopenia | 2021 |
Avatrombopag: First Global Approval.
Topics: Chronic Disease; Drug Approval; Humans; Liver Diseases; Receptors, Thrombopoietin; Thiazoles; Thiophenes; Thrombocytopenia; United States; United States Food and Drug Administration | 2018 |
Avatrombopag maleate for the treatment of periprocedural thrombocytopenia in patients with chronic liver disease.
Topics: Animals; Chronic Disease; Drug Interactions; Hematologic Agents; Humans; Liver Diseases; Perioperative Period; Thiazoles; Thiophenes; Thrombocytopenia; Treatment Outcome | 2018 |
New oral anticoagulants in practice: pharmacological and practical considerations.
Topics: Administration, Oral; Aging; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Complementary Therapies; Dabigatran; Drug Interactions; Drug Monitoring; Humans; International Normalized Ratio; Kidney Diseases; Liver Diseases; Morpholines; Pyrazoles; Pyridones; Rivaroxaban; Sex Factors; Stroke; Thiophenes; Warfarin | 2014 |
Management of Thrombocytopenia in Chronic Liver Disease: Focus on Pharmacotherapeutic Strategies.
Topics: Benzoates; Chronic Disease; Disease Management; Hepatitis C, Chronic; Humans; Hydrazines; Liver Diseases; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoietin | 2015 |
Answers to the most common questions about the hepatic safety profile of duloxetine.
Topics: Antidepressive Agents; Chemical and Drug Induced Liver Injury; Depressive Disorder; Drug Approval; Drug Labeling; Duloxetine Hydrochloride; Humans; Liver Diseases; Risk Assessment; Thiophenes; United States | 2008 |
Hepatic effects of duloxetine-II: spontaneous reports and epidemiology of hepatic events.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Adverse Drug Reaction Reporting Systems; Age Distribution; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Child; Consumer Product Safety; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Liver; Liver Diseases; Male; Middle Aged; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Sex Distribution; Thiophenes; Young Adult | 2008 |
Hepatic effects of duloxetine-I: non-clinical and clinical trial data.
Topics: Adrenergic Uptake Inhibitors; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Biomarkers; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Consumer Product Safety; Drug Evaluation, Preclinical; Duloxetine Hydrochloride; Humans; Liver; Liver Diseases; Risk Assessment; Risk Factors; Selective Serotonin Reuptake Inhibitors; Species Specificity; Thiophenes | 2008 |
Therapeutic potential of dithiolethiones for hepatic diseases.
Topics: Animals; CCAAT-Enhancer-Binding Protein-beta; Fatty Liver; Glutathione Transferase; Humans; Inactivation, Metabolic; Insulin Resistance; Liver; Liver Cirrhosis; Liver Diseases; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Protein Kinases; Pyrazines; Receptors, Aryl Hydrocarbon; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Thiones; Thiophenes; TOR Serine-Threonine Kinases | 2009 |
The laboratory and the new oral anticoagulants.
Topics: Administration, Oral; Anticoagulants; Benzimidazoles; beta-Alanine; Blood Coagulation Tests; Dabigatran; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Hemostasis; Humans; Liver Diseases; Morpholines; Pyrazoles; Pyridones; Renal Insufficiency; Rivaroxaban; Thiophenes | 2013 |
Anticoagulant therapy with the oral direct factor Xa inhibitors rivaroxaban, apixaban and edoxaban and the thrombin inhibitor dabigatran etexilate in patients with hepatic impairment.
Topics: Absorption; Anticoagulants; Benzimidazoles; Dabigatran; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Humans; Liver Diseases; Metabolic Clearance Rate; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Thiophenes; Thrombin; Tissue Distribution; Venous Thromboembolism | 2013 |
Heme oxygenase-1 as a potential therapeutic target for hepatoprotection.
Topics: Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Garlic; Heme Oxygenase-1; Humans; Liver; Liver Diseases; Metals, Heavy; Pyrazines; Signal Transduction; Thiones; Thiophenes | 2006 |
3 trial(s) available for thiophenes and Liver Dysfunction
| Article | Year |
|---|---|
The Influence of Renal or Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Oliceridine.
Topics: Acute Pain; Administration, Intravenous; Adult; Case-Control Studies; Female; Half-Life; Healthy Volunteers; Humans; Kidney Failure, Chronic; Ligands; Liver Diseases; Male; Middle Aged; Receptors, Opioid, mu; Safety; Severity of Illness Index; Spiro Compounds; Thiophenes | 2020 |
Avatrombopag increases platelet count but not platelet activation in patients with thrombocytopenia resulting from liver disease.
Topics: Blood Platelets; Chronic Disease; Double-Blind Method; Hematologic Agents; Humans; Liver Diseases; Platelet Activation; Platelet Count; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoiesis; Time Factors; Treatment Outcome; United States | 2018 |
Influence of hepatic impairment on the pharmacokinetics of the dopamine agonist rotigotine.
Topics: Administration, Cutaneous; Adult; Area Under Curve; Biological Availability; Biotransformation; Dopamine Agonists; Humans; Hungary; Liver; Liver Diseases; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Risk Assessment; Severity of Illness Index; Slovakia; Tetrahydronaphthalenes; Thiophenes; Transdermal Patch | 2014 |
12 other study(ies) available for thiophenes and Liver Dysfunction
| Article | Year |
|---|---|
An evaluation of avatrombopag for the treatment of thrombocytopenia.
Topics: Humans; Liver Diseases; Purpura, Thrombocytopenic, Idiopathic; Thiazoles; Thiophenes; Thrombocytopenia | 2021 |
Sinusoidal protection by sphingosine-1-phosphate receptor 1 agonist in liver ischemia-reperfusion injury.
Topics: Animals; Antigens, CD; Cadherins; Cytokines; Drug Evaluation, Preclinical; Endothelial Cells; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type III; Oxadiazoles; Proto-Oncogene Proteins c-akt; Random Allocation; Receptors, Lysosphingolipid; Reperfusion Injury; Sphingosine-1-Phosphate Receptors; Thiophenes; Vascular Cell Adhesion Molecule-1 | 2018 |
What Did We Learn From the ADAPT Trials?
Topics: Humans; Liver Diseases; Platelet Transfusion; Thiazoles; Thiophenes; Thrombocytopenia | 2019 |
New oral anticoagulants: a practical guide on prescription, laboratory testing and peri-procedural/bleeding management. Australasian Society of Thrombosis and Haemostasis.
Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Blood Coagulation Tests; Blood Loss, Surgical; Contraindications; Dabigatran; Drug Interactions; Drug Monitoring; Drug Substitution; Elective Surgical Procedures; Emergencies; Hematoma, Epidural, Spinal; Hemorrhage; Humans; Kidney Diseases; Liver Diseases; Morpholines; Patient Selection; Pyrazoles; Pyridones; Rivaroxaban; Stroke; Thiophenes; Thrombophilia | 2014 |
Erdosteine modulates radiocontrast-induced hepatotoxicity in rat.
Topics: Animals; Catalase; Chemical and Drug Induced Liver Injury; Contrast Media; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Liver Diseases; Male; Radiopharmaceuticals; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Thioglycolates; Thiophenes | 2009 |
Successful and well-tolerated second line therapy with cetuximab, irinotecan, and raltitrexed in progressive liver disease due to metastatic colon cancer.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colonic Neoplasms; Humans; Irinotecan; Liver Diseases; Liver Neoplasms; Male; Quinazolines; Thiophenes | 2008 |
Pharmacokinetics and pharmacodynamics of prasugrel in subjects with moderate liver disease.
Topics: Adult; Aged; Female; Humans; Liver Diseases; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes | 2009 |
Sphinganine-1-phosphate protects kidney and liver after hepatic ischemia and reperfusion in mice through S1P1 receptor activation.
Topics: Acute Kidney Injury; Animals; Extracellular Signal-Regulated MAP Kinases; Ischemia; Kidney; Liver; Liver Diseases; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Oxadiazoles; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; Reperfusion Injury; Signal Transduction; Sphingosine; Thiophenes | 2010 |
[Comparative studies on intravenous & oral reducdyn treatment of acute & chronic liver diseases].
Topics: Administration, Intravenous; Administration, Oral; Cysteine; Fructose; Humans; Liver Diseases; Thiophenes | 1958 |
Protective effects of erdosteine on doxorubicin-induced hepatotoxicity in rats.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Chemical and Drug Induced Liver Injury; Doxorubicin; Lipid Peroxidation; Liver; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Thioglycolates; Thiophenes | 2007 |
Renal and hepatic necrosis after metabolic activation of 2-substituted furans and thiophenes, including furosemide and cephaloridine.
Topics: Animals; Cephaloridine; Chemical and Drug Induced Liver Injury; Furans; Furosemide; In Vitro Techniques; Kidney; Kidney Diseases; Liver; Liver Diseases; Male; Mice; Microsomes; Necrosis; Thiophenes | 1977 |
Variation in serum binding of tertatolol mediated by disease-induced modification of alpha-acid glycoprotein concentration.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Proteins; Fatty Acids, Nonesterified; Female; Humans; Inflammation; Kidney Diseases; Liver Diseases; Male; Middle Aged; Orosomucoid; Propanolamines; Protein Binding; Thiophenes | 1988 |