thiophenes has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akahane, K; Björn, N; Inukai, T; Keszei, M; Lotfi, K; Madapura, HS; Malyukova, A; Nagy, N; Nguyen, TTT; Salamon, D; Stenke, L; Tamai, M; Ujvari, D; Wallvik, J; Yektaei-Karin, E; Zovko, A | 1 |
| Chen, GQ; Fang, ZX; Gao, FH; Gao, SM; Jin, J; Jing, B; Lei, H; Liu, CX; Liu, LG; Liu, M; Lu, Y; Shan, HZ; Tong, Y; Wang, WW; Wu, YL; Wu, YZ; Xia, L; Xiao, XH; Xu, HZ; Yang, L; Zheng, JK; Zhou, L | 1 |
| Cho, HC; Kuo, SC; Lee, CY; Lee, MR; Lu, CC; Tsai, FJ; Tsai, SC; Wen, YF; Yang, JS | 1 |
| Jin, J; Lei, H; Li, X; Liu, M; Luo, H; Wu, Y; Xu, H; Yang, L | 1 |
| Fukuda, T; Kasama, T; Miura, O; Suwa, S; Uchida, E; Watanabe, K; Yoshimoto, R | 1 |
| Cao, R; Huang, N; Wang, Y | 1 |
| Gong, FJ; Li, RJ; Liu, JH; Peng, HL; Zhang, GS | 1 |
| Barutca, S; Bolaman, Z; Kadikoylu, G; Meydan, N; Yavasoglu, I | 1 |
| Gibson, W; Jackman, AL; Kimbell, R; Kobayashi, H; Miyachi, H; Takemura, Y | 1 |
| Kobayashi, H; Ohnuma, T; Takemura, Y | 1 |
10 other study(ies) available for thiophenes and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
| Article | Year |
|---|---|
Combination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells.
Topics: Antigens, CD34; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Survival; Clone Cells; Drug Resistance, Neoplasm; Drug Synergism; Hematopoietic Stem Cells; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphate-Binding Proteins; Poly(ADP-ribose) Polymerases; Pore Forming Cytotoxic Proteins; Protein Kinase Inhibitors; Pyrimidines; Pyroptosis; Small Molecule Libraries; Thiophenes | 2021 |
Targeting USP47 overcomes tyrosine kinase inhibitor resistance and eradicates leukemia stem/progenitor cells in chronic myelogenous leukemia.
Topics: Animals; Cell Proliferation; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice, Knockout; Neoplastic Stem Cells; Proteasome Endopeptidase Complex; Protein Binding; Protein Kinase Inhibitors; Protein Stability; Proteolysis; ras Proteins; RNA, Messenger; Signal Transduction; STAT5 Transcription Factor; Thiophenes; Ubiquitin Thiolesterase; Ubiquitin-Specific Proteases; Xenograft Model Antitumor Assays; Y-Box-Binding Protein 1 | 2021 |
ITR‑284 modulates cell differentiation in human chronic myelogenous leukemia K562 cells.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Forkhead Box Protein M1; Fusion Proteins, bcr-abl; GATA1 Transcription Factor; GATA2 Transcription Factor; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; NF-E2 Transcription Factor, p45 Subunit; Proto-Oncogene Proteins c-myc; Thiophenes; Tretinoin; Zinc Finger Protein GLI1 | 2018 |
Chk1 inhibitors overcome imatinib resistance in chronic myeloid leukemia cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Pyrazoles; Pyrimidines; Thiophenes; Urea; Xenograft Model Antitumor Assays | 2018 |
TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation.
Topics: Adult; Aged; Aged, 80 and over; Blast Crisis; Cell Line, Tumor; Cell Proliferation; Female; Fusion Proteins, bcr-abl; Gene Expression Regulation, Neoplastic; HLA-A24 Antigen; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Protein Phosphatase 2; Quinolones; Thiophenes; Young Adult | 2019 |
Discovery of 2-Acylaminothiophene-3-Carboxamides as Multitarget Inhibitors for BCR-ABL Kinase and Microtubules.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Microtubules; Molecular Docking Simulation; Point Mutation; Protein Kinase Inhibitors; Thiophenes | 2015 |
Dup-697, a specific COX-2 inhibitor, suppresses growth and induces apoptosis on K562 leukemia cells by cell-cycle arrest and caspase-8 activation.
Topics: Apoptosis; Bone Marrow Cells; Caspase 8; Cell Cycle; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Enzyme Activation; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Thiophenes | 2008 |
Chronic myeloid leukemia following the treatment of rectal adenocarcinoma.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Fluorouracil; Fusion Proteins, bcr-abl; Humans; In Situ Hybridization, Fluorescence; Irinotecan; Leucovorin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Neoplasms; Male; Neoplasms, Second Primary; Organoplatinum Compounds; Oxaliplatin; Philadelphia Chromosome; Quinazolines; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Thiophenes | 2008 |
Cellular pharmacokinetics of ZD1694 in cultured human leukaemia cells sensitive, or made resistant, to this drug.
Topics: Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Folic Acid; Humans; Intracellular Fluid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Polyglutamic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Tetrahydrofolate Dehydrogenase; Thiophenes; Thymidylate Synthase; Tritium; Tumor Cells, Cultured | 1996 |
Variable expression of RFC1 in human leukemia cell lines resistant to antifolates.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Antagonists; Humans; Leucovorin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Tetrahydrofolate Dehydrogenase; Thiophenes; Tumor Cells, Cultured | 1998 |