thiophenes has been researched along with Intraocular Pressure in 453 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (1.99) | 18.7374 |
1990's | 111 (24.50) | 18.2507 |
2000's | 206 (45.47) | 29.6817 |
2010's | 114 (25.17) | 24.3611 |
2020's | 13 (2.87) | 2.80 |
Authors | Studies |
---|---|
Chung, HW; Ji, MJ; Kim, YY; Park, JH; Yoo, C; Yoon, EG | 1 |
Çakmak, K; Erbil, H; Korkmaz, Ş; Mesci, C | 1 |
Cardoso, VN; Castilho, RO; Cronemberger, S; Faraco, AAG; Fernandes, SOA; Ferreira, AJ; Foureaux, G; Franca, JR; Fuscaldi, LL; Nogueira, JC; Ribeiro, TG; Yoshida, MI | 1 |
Bek, T; Tilma, KK | 1 |
Ha, A; Jeoung, JW; Kim, YK; Park, KH; Wy, S | 1 |
Huang, S; Xing, Y; Zhang, K; Zhu, L | 1 |
Biagioli, E; Galli, F; Longo, A; Michelessi, M; Oddone, F; Quaranta, L; Riva, I; Rulli, E; Uva, MG; Weinreb, RN | 1 |
Esfandiari, H; Tanna, AP; Teramoto, K | 1 |
Chen, E; Chiang, A; Garg, SJ; Ho, AC; Hsu, J; Jenkins, TL; Mikhail, M; Obeid, A; Patel, SN; Shah, CP; Spirn, MJ; Vander, JF; Wibbelsman, TD; Wolfe, JD | 1 |
Holló, G; Hutnik, CML; Katsanos, A; Katz, LJ; Konstas, AG; Pfeiffer, N; Quaranta, L; Schmetterer, L; Teus, MA; Uusitalo, H | 1 |
Chen, LC; Chuang, LH; Huang, SM; Lin, YH; Su, WW | 1 |
Fan, N; Huang, L; Lan, C; Liu, G; Liu, X; Luo, X; Tan, J; Tang, L; Zhou, L; Zhu, Y | 1 |
Adachi, M; Aihara, M; Fukuchi, T; Matsuo, H; Sasaki, N; Togano, T | 1 |
Li, LU; Zhang, H; Zhao, Y | 1 |
Andishmand, L; Bavarsad, N; Kouchak, M; Malekahmadi, M; Saki Malehi, A | 1 |
Biagioli, E; Galli, F; Katsanos, A; Longo, A; Poli, D; Quaranta, L; Riva, I; Rulli, E; Torri, V; Uva, MG; Weinreb, RN | 1 |
Lee, TE; Park, YM | 1 |
Belcaro, G; Feragalli, B; Gizzi, C; Hosoi, M; Hu, S; Torino-Rodriguez, P | 1 |
Kim, YY; Na, KH; Park, JH; Yoo, C | 1 |
Afify, AEMR; Afify, EAMR; Elsayed, I; Gad, MK; Mohamed, MI | 1 |
Chiang, A; Ehmann, D; Gao, X; Ho, AC; Hsu, J; Obeid, A; Park, CH; Sridhar, J | 1 |
Abdelrehim, RT; Fouda, NH; Habib, BA; Hegazy, DA | 1 |
Bello, TO; Ogunleye, T; Olawoye, OO; Sarimiye, TF | 1 |
Biagioli, E; Galli, F; Katsanos, A; Longo, A; Oddone, F; Poli, D; Quaranta, L; Riva, I; Rulli, E; Torri, V; Uva, MG; Weinreb, RN | 1 |
Bobic-Radovanovic, A; Bozic, M; Knezevic, M; Marjanovic, I; Stojkovic, M | 1 |
Hwang, CK; Kim, BJ; Kolomeyer, AM | 1 |
Samuelson, TW | 1 |
Boevé, MH; de Gee, R; Djajadiningrat-Laanen, SC; Elders, DJ; Koele, LE; Slenter, IJM; Vermeer, LW | 1 |
Farrahi, F; Kouchak, M; Mahmoodzadeh, M | 1 |
Jung, JH; Kim, SI; Lee, JE; Lee, SM; Shin, J | 1 |
Eichhorn, M | 1 |
Chung, IY; Han, YS; Kim, GN; Park, JM; Seo, SW; Yoo, JM | 1 |
Balbaba, M; Çelebi, S; Ulaş, F | 1 |
Prokosch, V; Schallenberg, M; Thanos, S | 2 |
Feke, GT; Pasquale, LR; Rhee, DJ; Turalba, AV | 1 |
Giannopoulos, T; Haidich, AB; Holló, G; Konidaris, V; Konstas, AG; Mikropoulos, DG; Paschalinou, E; Samples, JR; Voudouragkaki, IC | 1 |
Cardoso, VN; Faraco, AA; Fernandes, RS; Fernandes, SO; Ferreira, AJ; Foureaux, G; Franca, JR; Fulgêncio, GO; Menezes, GB; Nogueira, BS; Nogueira, JC; Oliveira, GP; Raizada, MK | 1 |
Aliyeva, S; Cunha-Vaz, J; Floriani, I; Hoffmann, EM; Miglior, S; Pfeiffer, N; Rulli, E; Torri, V; Zeyen, T | 1 |
Baser, EF; Gülhan, C; Öztürk, B; Seymenoğlu, G | 1 |
Oláh, Z; Veselovský, J | 3 |
Atkins, RM; Dees, DD; Esson, DW; Fritz, KJ; Knollinger, AM; Maclaren, NE; Sheehan Gaerig, AM | 1 |
Akçali, G; Bozkurt, KT; Güney, E; Sezgin Akçay, Bİ; Unlü, C | 1 |
Asgrimsdottir, GM; Gottfredsdottir, MS; Gudmundsdottir, BS; Hardarson, SH; Jansook, P; Jóhannesson, G; Kurkov, SV; Loftsson, T; Petursdottir, D; Stefánsson, E | 1 |
Bernardo, FP; Gomes, B; Marques, FP; Portes, AL; Safady, MV; Santhiago, MR; Turiel, PR | 1 |
He, M; Huang, W; Wang, W | 1 |
Baršauskaitė, R; Dilienė, V; Harris, A; Janulevičienė, I; Kuzmienė, L; Šiaudvytytė, L; Siesky, B | 1 |
Abegão Pinto, L; Gerlier, L; Stalmans, I; Vandewalle, E | 1 |
Ghahari, E; Pakravan, M; Rad, SS; Yaseri, M; Yazdani, S | 1 |
Garg, SJ; Gerstenblith, AT; Hsu, J; London, NJ; Maguire, JI; Park, C; Sivalingam, A; Spirn, MJ | 1 |
Ahmad, FJ; Anwar, M; Garg, V; Jain, GK; Khar, RK; Talegaonkar, S; Warsi, MH | 1 |
Agarwal, P; Agarwal, R; Ismail, NM; Kannan Kutty, M; Kapitonova, MY; Razali, N; Salmah Bakar, N; Smirnov, A | 1 |
Allbaugh, RA; Ben-Shlomo, G; Dufour, VL; Flinn, AM; Griggs, AN; Peterson, CS; Tofflemire, KL; Whitley, DR; Whitley, EM | 1 |
García-López, A; Hartleben, C; Jiménez-Román, J; Paczka, JA | 1 |
Anand, G; Gelber, AC; Kochar, B; Shan, SJ; Zinreich, SJ | 1 |
Cobbs, M; Dinh, DM; Edwards, MP; Gukasyan, HJ; Huang, Q; Lafontaine, JA; Mehta, S; Patterson, BD; Rewolinski, DA; Richardson, PF; Rui, EY | 1 |
Akdemir, A; Bozdag, M; Carta, F; Isik, S; Lanzi, C; Masini, E; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Moore, GH; Quan, AV; Tsui, I | 1 |
Carbia, BE; Chauhan, A; Hsu, KH; Plummer, C | 1 |
Chatziralli, IP; Demopoulos, CA; Moschos, MM; Papakonstantinou, VD; Stamatakis, G; Tsatsos, M | 1 |
Busse, C; Newton, JR; Stavinohova, R | 1 |
Ha, SJ; Seo, du R | 1 |
Lee, NY; Park, CK; Park, HY | 2 |
Lisboa, M; Mota, M; Pedrosa, C; Prieto, I; Ramalho, M; Silva, D; Vaz, FT | 1 |
Chandra, S; Deo, K; Duong, TQ; Kiel, JW; Muir, ER | 1 |
Elsaied, HM; Fouad, PH; Galose, MS; Macky, TA | 1 |
Nucci, P; Sacchi, M; Specchia, C; Villani, E; Williams, SE | 1 |
Fukuda, M; Sasaki, H; Shibata, N; Shibata, S; Shibata, T; Sugiyama, K; Takeda, N | 1 |
Biagioli, E; Galli, F; Hollander, L; Katsanos, A; Longo, A; Poli, D; Quaranta, L; Riva, I; Rulli, E; Torri, V; Uva, MG; Weinreb, RN | 1 |
Fridley, C; Fu, J; Gedam, M; Hanes, J; Hu, Q; Liu, W; Liu, Y; Pitha, I; Quigley, HA; Sun, F | 1 |
Konstantinidis, A; Kozobolis, V; Labiris, G; Panos, GD | 1 |
Cong, X; Molloy, BL; Watson, C | 1 |
Boboridis, KG; Haidich, AB; Kapis, P; Katsanos, A; Konstas, AG; Marinopoulos, K; Mikropoulos, DG; Pagkalidou, E; Panayiotou, D; Quaranta, L; Voudouragkaki, IC | 1 |
Armour, MD; Dees, DD; Greller, A; Madsen, R; Paglia, D; Spahn, KJ; Wagner, LS | 1 |
Bell, K; Keicher, A; Lorenz, K; Pfeiffer, N; Renieri, G; Ruckes, C; Thieme, H; Wasielica-Poslednik, J | 1 |
Choy, YB; Huh, BK; Kim, SN; Kim, YK; Lee, SH; Park, CG; Park, KH; Park, MA; Won, H | 1 |
Besada, E; Frauens, BJ; Shechtman, D | 1 |
Beckers, HJ; Hendrikse, F; Schouten, JS; van der Valk, R; Webers, CA | 1 |
Feldman, RM; Galet, VA; Jia, G; Smugar, SS; Stewart, RH; Stewart, WC | 1 |
Martínez, A; Sánchez, M | 4 |
Byeon, SH; Kim, SE; Kwon, OW; Park, YS; Song, JH | 1 |
Dimopoulos, AT; Konstas, AG; Mikropoulos, D; Moumtzis, G; Nelson, LA; Stewart, WC | 1 |
Boyer, S; Gay, D | 1 |
Oláh, Z; Veselá, A; Veselovský, J | 1 |
Kim, JH; Lee, NY; Park, CK; Park, HY | 1 |
Evans, RM; Mallick, S; Stewart, RH; Vold, SD; Walters, T | 1 |
Barbosa, WL; Grigera, DE; Hatanaka, M; Jordao, M; Susanna, R | 1 |
Călugăru, D; Călugăru, M | 5 |
Bogner, B; Kiel, JW; Reitsamer, HA; Tockner, B | 1 |
Chalkidou, S; Georgopoulos, G; Halkiadakis, I; Kostakou, A; Markomichelakis, NN; Papakonstantinou, D | 1 |
Cai, JP; Cheng, JW; Li, Y; Wei, RL; Xi, GL | 1 |
Martínez, A; Sánchez-Salorio, M | 2 |
Eysteinsson, T; Gottfredsdottir, MS; Hardarson, SH; Harris, A; Karlsson, RA; Stefánsson, E; Traustason, S | 1 |
Galet, VA; Jia, G; Olander, KW; Smugar, SS; Stewart, WC | 1 |
Almaden, CD; Anderson, S; Carreiro, S; Fortner, J; Gukasyan, H; Krauss, A; Lafontaine, J; Nair, S; Niesman, M; Prasanna, G; Rui, E; Sartnurak, S; Wells, P; Wu, G; Xiang, C; Zhang, E | 1 |
Cai, JP; Cheng, JW; Wei, RL | 1 |
Chartrand, JP; Hollander, DA; Nixon, DR; Piemontesi, RL; Simonyi, S; Yan, DB | 1 |
Abdel-Naim, AB; Afouna, MI; Al-Marzoqi, A; Khedr, A | 1 |
Cheng, JW; Li, Y; Wei, RL | 1 |
Jamshidian-Tehrani, M; Mehdizadeh, M; Nowroozzadeh, MH | 1 |
Laxmana Rao, HB; Sekhar, GC | 1 |
Bournias, TE; Lai, J | 1 |
Niutta, PP; Pugliese, A; Pugliese, M; Scardillo, A | 1 |
Anderson, S; Fortner, J; Luu, KT; Prasanna, G; Vicini, P; Xiang, C; Zhang, EY | 1 |
Bwatwa, J; Ehrlich, R; Harris, A; Kagemann, L; McCranor, L; Miller, B; Regev, G; Siesky, B; Stefansson, E | 1 |
Birch, MK; Doherty, MD; Figueiredo, FC; Wride, NK | 1 |
Fuchsjäger-Mayrl, G; Garhöfer, G; Georgopoulos, M; Hommer, A; Pemp, B; Schmetterer, L; Vass, C; Weigert, G | 1 |
Buys, YM; Fisher, JA; Flanagan, JG; Hudson, C; Markowitz, SN; Rachmiel, R; Trope, GE; Venkataraman, ST | 1 |
Aguirre, SA; Huang, W; Jessen, B; Prasanna, G | 1 |
Grunden, JW; Kwok, K; Miglior, S | 1 |
Earl, M; Nguyen, QH | 1 |
Fishman, GA; Genead, MA; Walia, S | 1 |
Bauer, P; Eichler, HG; Findl, O; Groke, I; Schmetterer, L; Sycha, T; Vass, C | 1 |
Katz, LJ; Razeghinejad, MR; Sawchyn, AK | 1 |
Calvo-González, C; Fernández-Vidal, A; García-Feijoó, J; García-Sánchez, J; Martínez-de-la-Casa, JM; Méndez-Hernández, C; Sáenz-Francés, F | 1 |
Beaver, Y; Borchardt, AJ; Cayanan, CS; Clark, AF; Cook, TG; Cramp, J; Davis, RL; Gardiner, EM; Hellberg, MR; Kahraman, M; McLaughlin, MA; Noble, SA; Prins, TJ; Shiau, AK | 1 |
Adamsons, IA; Getson, AJ; Hewitt, DJ; Ho, TW; Laurence, JK; Lines, CR; Shedden, A | 1 |
Ehrlich, R; Fuksinska, B; Harris, A; Robaszkiewicz, J; Siemiatkowska, A; Siesky, B; Stankiewicz, A; Wierzbowska, J; Zegadlo, A | 1 |
Häfliger, IO; Pajic, B; Pajic-Eggspuehler, B | 1 |
Bastien, NR; Behki, R; Boucher, S; Crichton, AC; Harasymowycz, P; Hutnik, CM; Ibrahim, F; Liao, C; Rifkind, AW; Sampalis, JS; Solomon, L | 1 |
De Majo, M; Niutta, PP; Pugliese, A; Pugliese, M; Scardillo, A | 1 |
Führer, K; Lorenz, K; Pfeiffer, N; Renieri, G; Scheithe, K; Thieme, H | 1 |
Hendrikse, F; Peeters, A; Prins, MH; Schouten, JS; Webers, CA | 1 |
Ehrlich, R; Grabska-Liberek, I; Harris, A; Misiuk-Hojło, M; Mulak, M; Romanowska-Dixon, B; Sierdziński, J; Siesky, B; Stankiewicz, A; Szuścik, I; Wasyluk, J; Wierzbowska, J | 1 |
David, R; Kurtz, S; Newman, H | 1 |
Stamer, WD; Sumida, GM | 1 |
Petrović, MJ; Petrović, N; Srećković, S; Vukosavljević, M | 1 |
García Sánchez, J; García-Feijoó, J; Herrero-Vanrell, R; Martínez-de-la-Casa, JM; Sáenz-Francés, F; Sánchez-Pulgarín, M; Santos-Bueso, E | 1 |
Cabrita, AM; de Sousa, HC; Fontes Ribeiro, CA; Gaspar, MN; Gil, MH; Natu, MV | 1 |
Altan, C; Altinkaynak, H; Bozkurt, E; Demirok, A; Kara, N; Satana, B; Yilmaz, OF | 1 |
Bianchi, PE; Bordin, M; Pasinetti, GM; Rossi, GC; Sandolo, F | 1 |
Araie, M; Kitazawa, Y | 1 |
Demircheva, I; Gatchev, E; Hristova, R; Kolev, E; Koytchev, R; Petrov, A; Richter, W; Tegel, F; Thyroff-Friesinger, U | 1 |
Altıntaş, O; Cağlar, Y; Gök, M; Yüksel, N | 1 |
Betts, DM; Camaño-Garcia, G; Carriquiry, AL; Kuehn, MH; McLellan, GJ; Sigle, KJ | 1 |
Barton, K; Gill, NK; Haidich, AB; Konstas, AG; Mikropoulos, DG; Quaranta, L; Riva, I; Yan, DB | 1 |
Gulkilik, G; Oba, E; Odabası, M | 1 |
Abrams, L; Cantor, L; Ehrlich, R; Harris, A; Hollander, DA; Rusia, D; Shoja, MM; Shoshani, Y; Siesky, B; Williams, JM | 1 |
Beckers, HJ; Hendrikse, F; Jansonius, NM; Schouten, JS; Severens, JL; van Gestel, A; Webers, CA | 1 |
Altan, C; Eren, MH; Gungel, H; Pasaoglu, IB; Sabanci, S | 1 |
Cheng, JW; Cheng, SW; Lu, GC; Wei, RL; Yu, DY | 1 |
Fan, S; Gangahar, C; Gulati, V; Maslonka, MA; Toris, CB; Zhao, M | 1 |
Ohguro, H; Ohguro, I | 1 |
Congdon, NG; Friedman, DS; Gilbert, D; Goggins, W; Kader, MA; Krishnadas, R; Quigley, HA; Ramakrishnan, R; Tielsch, J | 1 |
Huber-van der Velden, KK; Klamann, MK; Lux, A; Remky, A; Severing, K; Winterhalter, S | 1 |
Levin, AV; Soin, K | 1 |
Allbaugh, RA; Crumley, WR; Rankin, AJ | 1 |
Dot, C; El Chehab, H; Giraud, JM; Le Corre, A; Ract-Madoux, G; Swalduz, B | 1 |
Inoue, K; Shiokawa, M; Soeda, S; Sugahara, M; Tomita, G; Wakakura, M | 1 |
Aldahmesh, MA; Alkuraya, FS; Khan, AO; Mohamed, JY | 1 |
Budengeri, P; Cai, JP; Cheng, JW; Wei, RL | 1 |
Larsson, LI; Mishima, HK; Orzalesi, N; Rossetti, L; Takamatsu, M | 1 |
Bron, AM; Emmerich, KH | 1 |
Adamsons, I; Cunha-Vaz, J; Miglior, S; Pfeiffer, N; Torri, V; Zeyen, T | 4 |
Bron, A | 1 |
Bucci, MG; Centofanti, M; Gregori, D; Manni, G; Migliardj, R; Oddone, F; Scipioni, M | 1 |
Bottoli, A; Fogagnolo, P; Fumagalli, E; Invernizzi, T; Orzalesi, N; Rossetti, I | 1 |
Cantor, LB | 1 |
Ermis, SS; Inan, UU; Ozturk, F | 2 |
Honrubia, FM; Larsson, LI; Spiegel, D | 1 |
Lanzl, I; Nagel, E; Vilser, W | 2 |
Day, DG; Leech, J; Schacknow, PN; Sharpe, ED; Stewart, JA; Stewart, WC; Wand, M | 1 |
Konstas, AG; Kozobolis, VP; Leech, J; Stewart, WC; Tersis, I | 1 |
Boyle, DR; Cassel, DA; DeLucca, PT; Fletcher, CA; Greff, LJ; Johnson-Pratt, LR; Kolodny, AH; Polis, AB; Sall, KN; Skobieranda, F | 1 |
Recker, K | 1 |
Amaral, M; Arieta, C; Crosta, C; de Carvalho Moreira Filho, D; José, N; Matuda, E | 1 |
Bottoli, A; Fogagnolo, P; Fumagalli, E; Orzalesi, N; Rossetti, L | 1 |
Brignoli, R; Mermoud, A; Ravinet, E | 1 |
Hommer, A; Kapik, B; Shams, N | 1 |
Pajic, B | 1 |
Dziezyc, J; Rainbow, ME | 1 |
Cantor, LB; Hoop, J; Katz, LJ; Lin, JC; Samuel, F; Spaeth, GL | 1 |
Bacharach, J; Delgado, MF; Iwach, AG | 1 |
Flammer, J; Gugleta, K; Orgül, S | 1 |
Czechowicz-Janicka, K; Kałuzny, J; Kałuzny, JJ; Krajewska, M; Leech, JN; Orzalkiewicz, A; Stewart, JA; Stewart, WC; Szaflik, J; Zaleska, A | 1 |
Houliara, D; Konstas, AG; Papapanos, P; Stewart, WC; Tersis, I | 1 |
Cimino, L; Gandolfi, SA; Mora, P; Orzalesi, N; Rossetti, L; Tardini, M | 1 |
Mozaffari, E; Reardon, G; Schwartz, GF | 1 |
Nesher, R; Ticho, U | 1 |
Arend, O; Harris, A; Remky, A; Wolter, P | 1 |
Findl, O; Georgopoulos, M; Kiss, B; Menapace, R; Petternel, V; Rainer, G; Sacu, S; Schmid, K | 1 |
Akaishi, T; Hara, H; Kuwayama, Y; Matsugi, T; Miyawaki, N; Shimazaki, A | 1 |
Chen, YF; Hung, PT; Yang, CH | 1 |
Bauer, P; Eichler, H; Findl, O; Groke, I; Schmetterer, L; Sycha, T; Vass, C | 1 |
Casini, A; Menabuoni, L; Mincione, F; Scozzafava, A; Starnotti, M; Supuran, CT | 1 |
Bernstein, P; Coleman, AL; Lerner, F; Whitcup, SM | 1 |
Araie, M; Azuma, I; Hamanaka, T; Kitazawa, Y; Origasa, H; Shirato, S; Tomita, G | 1 |
Bang, K; Eysteinsson, T; Jensen, PK; Kiilgaard, JF; la Cour, M; Pedersen, DB; Stefánsson, E | 1 |
Larsson, LI; Tsukamoto, H | 1 |
Adamsons, IA; Airaksinen, PJ; Fechtner, RD; Getson, AJ; Lines, CR | 1 |
Amoako-Mensah, T; Buehl, W; Eichler, HG; Fuchsjäger-Mayrl, G; Georgopoulos, M; Kircher, K; Rainer, G; Schmetterer, L; Vass, C; Wally, B | 1 |
Hara, A; Maeda, K; Matsubara, M; Nakai, Y; Sawada, A; Yamamoto, T | 1 |
Feldman, RM; Sheu, WP; Shin, DH | 1 |
Iyer, SA; Neelakantan, A; Sherwood, MB; Vaishnav, HD | 1 |
Cassel, DA; DeLucca, PT; Hustad, CM; Kolodny, AH; Skobieranda, F; Solish, AM | 1 |
Fechtner, RD; Henry, C; Hughes, B; Lee, DA; Terry, S; Whitson, JT | 1 |
Camras, CB; Toris, CB; Yablonski, ME; Zhan, GL | 1 |
Arias Puente, A; Carrasco Font, C; García Sáenz, MC; Villarejo Díaz-Maroto, I | 1 |
Benz, MS; Eifrig, CW; Escalona-Benz, EM; Moore, JK; Murray, TG; Schiffman, JC; Yoder, DM | 1 |
Gressnerová, S; Oláh, Z; Veselá, A; Veselovský, J | 3 |
Beischel, CJ; Day, DG; Rhodes, JS; Sharpe, ED; Stewart, JA; Stewart, WC | 1 |
Christodoulakis, E; Konstas, AG; Kozobolis, VP; Lallos, N; Stewart, JA; Stewart, WC | 1 |
Sheu, WP; Susanna, R; Sussana, R | 1 |
Berke, S; Du, LT; Ehrenhaus, M; Francis, BA; Minckler, DS | 1 |
Ignat, F | 1 |
Langenbucher, A; Mardin, CY; Martus, P; Schlötzer-Schrehardt, U; Viestenz, A | 1 |
Buys, YM; Faingold, D; Flanagan, J; Guan, K; Hudson, C; Rawji, M; Trope, GE | 1 |
Czechowicz-Janicka, K; Kałuzny, J; Kałuzny, JJ; Krajewska, M; Leech, JN; Orzałkiewicz, A; Stewart, JA; Stewart, WC; Szaflik, J; Zaleska-Zmijewska, A | 1 |
Harris, A; Janulevicienë, I; Kagemann, L; McCranor, L; Siesky, B | 1 |
Bastian, CD; Dietlein, TS; Jordan, JF; Krieglstein, GK | 1 |
Bayer, A; Oeverhaus, U; Skrotzki, FE; Stewart, WC; Weiler, W | 1 |
Tressler, CS | 1 |
Aşagidag, A; Ermiş, SS; Inan, UU; Oztürk, F; Yaman, S | 1 |
Kaiserman, I; Kaiserman, N; Nakar, S; Vinker, S | 1 |
Abe, H; Fukuchi, T; Hashimoto, K; Matsuda, H; Seki, M; Tanaka, T; Togano, T; Ueda, J | 1 |
Georgiadis, N; Karabatsas, CH; Konstas, AG; Kotsimpou, A; Lallos, N; Stewart, JA; Stewart, WC | 1 |
Galambos, P; Klemm, M; Matthiessen, ET; Reuss, J; Richard, G; Wagenfeld, L; Wiermann, A; Zeitz, O | 1 |
Ikeda, H; Matsuyama, S; Mishima, HK; Noma, H; Tsukamoto, H | 1 |
Adamsons, IA; Fechtner, RD; Lines, CR; McCarroll, KA | 1 |
Fontanarosa, J; Henderer, JD; Moster, MR; Myers, J; Schmidt, C; Steinmann, WC; Wilson, RP | 1 |
Quigley, HA | 1 |
Adamsons, IA; Arango, S; Assaid, CA; Getson, AJ; Mills, MD; Ott, EZ | 1 |
Aggermann, T; Buehl, W; Eichler, HG; Fuchsjäger-Mayrl, G; Kolodjaschna, J; Polska, E; Rainer, G; Schmetterer, L; Vass, C; Wally, B; Weigert, G | 1 |
Ikeda, H; Mishima, HK; Mukai, S; Noma, H; Tsukamoto, H | 1 |
McEwan, GC; Patil, KA; Sarup, V; Sharma, SC; Thompson, C | 1 |
Ishikawa, S; Nakamura, Y; Sakai, H; Sawaguchi, S; Shinjyo, S | 1 |
Conkbayir, I; Simsek, T; Yanik, B; Zilelioglu, O | 1 |
Longo, A; Reibaldi, A; Reibaldi, M; Uva, MG | 1 |
Gandolfo, E; Gandolfo, F; Musig, A; Pizzolante, T; Quaranta, L; Rovida, F; Turano, R | 1 |
Jurisić, D; Lacmnovic-Loncar, V; Mandić, Z; Petric, I; Sesar, A; Sesar, I; Tomić, Z | 1 |
Maruyama, K; Shirato, S | 1 |
Baudouin, C; Bron, AM; Creuzot-Garcher, C; Lizard, G; Malvitte, L; Montange, T; Vejux, A | 1 |
Batista, WD; da Silva, LJ; Figueiredo, CR; Franklin, LM; Netto, JA; Suzuki, ER | 1 |
Campa, C; Costagliola, C; D'Angelo, S; Incorvaia, C; Lamberti, G; Parmeggiani, F; Perri, P; Sebastiani, A | 1 |
Goñi, FJ | 1 |
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Hendrikse, F; Prins, MH; Schouten, JS; van der Valk, R; Webers, CA; Zeegers, MP | 1 |
Harris, A; Malinovsky, VE; McCranor, L; Rechtman, E; Siesky, B; Sines, D; Yung, CW; Zalish, M | 1 |
Oksüz, H; Tamer, C | 1 |
Akyol, N; Celiker, U; Demir, T; Güler, M; Turgut, B; Türkçüoğlu, P | 1 |
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Konstas, AG; Kruft, B; Nelson, LA; Stewart, WC | 1 |
Clearkin, LG; Stewart, RM | 1 |
Efremova, R; Konstas, AG; Kozobolis, VP; Makridaki, I; Stewart, WC; Tsironi, S | 1 |
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Cantor, LB; Harris, A; Kagemann, L; Marques, C; McCranor, L; Siesky, B; Stefansson, E; Weitzman, Y; Werne, A | 1 |
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Fuchsjäger-Mayrl, G; Garhofer, G; Hommer, A; Resch, H; Schmetterer, L; Vass, C | 1 |
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Strahlman, E; Tipping, R; Vogel, R | 2 |
Palmberg, P | 1 |
Miyamoto, S; Sawa, M; Yamazaki, Y | 2 |
Cyrlin, M; Deasy, D; Esposito, D; Fazio, R; Lippa, EA; Panebianco, D; Shields, MB; Wilkerson, M; Yablonski, M | 1 |
Brechue, WF; Maren, TH | 3 |
Fineman, MS; Katz, LJ; Wilson, RP | 1 |
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Clineschmidt, CM; Strahlman, ER; Tipping, R; Vogel, R | 1 |
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Allingham, RR; Choudhri, SA; Cox, T; Damji, KF; Herndon, LW; Shields, MB | 1 |
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Alm, A; Brubaker, R; Larsson, LI; Maus, T; Wayman, L | 1 |
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Elliott, WR; Harris, A; Harrison, J; Kavanagh, J; Sponsel, WE; Trigo, Y | 1 |
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Bucci, MG; Centofanti, M; Manni, GL; Napoli, D; Parisi, V | 1 |
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Le Guilloux, JC | 1 |
Burnstein, Y; Higginbotham, EJ; Shelton, K | 1 |
Adamsons, I; Snyder, E; Strohmaier, K | 1 |
Brubaker, RF; Maus, TL; Vanlandingham, BD | 1 |
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Adamsons, IA; Boyle, JE; Ghosh, K; Gieser, DK | 2 |
Adamsons, I; DuBiner, H; Snyder, E; Strohmaier, K | 2 |
Adamsons, IA; Clineschmidt, CM; Snyder, E; Williams, RD | 2 |
Briganti, F; Menabuoni, L; Mincione, F; Mincione, G; Scozzafava, A; Supuran, CT | 2 |
Lukaris, A; Roberts-Harry, TJ; Rogers, ZA; Sells, M; Zohdy, GA | 1 |
Brubaker, R; Dinslage, S; McLaren, J | 1 |
Brubaker, RF; Larsson, LI; Maus, TL; Wayman, LL | 1 |
Gerdtham, U; Jönsson, L; Kobelt, G; Krieglstein, GK | 1 |
Adamsons, IA; Boyle, JE; Ostrov, CS; Polis, A | 1 |
Adamsons, IA; Hutzelmann, JE; Michael, AJ; Polis, AB | 1 |
Adamsons, I; Hutzelmann, J; Owens, S; Shedden, A; Vargas, E | 1 |
Pillunat, LE; Schmidt, KG; von Rückmann, A | 1 |
D'Andrea, A; D'Andrea, D; Ferreri, G | 1 |
Jörg, KM; Lachmann, C; Trinkmann, R | 1 |
Challa, P; Fanous, MM; Maren, TH | 1 |
Gebhardt, DO | 1 |
Güler, C; Kimal Arici, M; Topalkara, A | 1 |
Brucculeri, M; Hammel, T; Harris, A; Malinovsky, V; Martin, B | 1 |
Brown, SV; Cooke, DL; Dennis, RF; Epstein, RJ; Fraunfelder, FT; Konowal, A; Maguire, LJ; Morrison, JC; Verdier, DV | 1 |
Capeans, C; Gonzalez, F; Martinez, A; Perez, R; Sanchez-Salorio, M | 1 |
thoe Schwartzenberg, GW; Trope, GE | 1 |
Bron, A; Chapard, J; Creuzot-Garcher, C; D'Athis, P; Guerzider, V | 1 |
Odberg, T | 1 |
Böhm, AG; Klemm, M; Köller, AU; Pillunat, LE; Richard, G; Schmidt, KG | 1 |
Chang, MR; Cheng, Q; Hartenbaum, D; Le, HH; Lee, DA | 1 |
Hartenbaum, D; Maloney, S; Orillac, R; Sharpe, E; Vacarelli, L; Wilson, H | 1 |
Brubaker, RF; Ingram, CJ | 1 |
Adamsons, I; Gross, R; Pearson, J; Rusk, C; Sverrisson, T | 1 |
Buckley, EG; Freedman, SF; Portellos, M | 1 |
Findl, O; Georgopoulos, M; Menapace, R; Rainer, G; Schmetterer, K; Vass, C | 1 |
Chakraborty, P; Tinu, AT; Villada, JR | 1 |
Becker, R; Pillunat, LE; Schmidt, KG; von Rückmann, A | 1 |
Apatachioae, I; Chiselita, D; Poiata, I | 1 |
Damji, KF; Daneshvar, H; Gilberg, SM; Goela, A | 1 |
Emmerich, KH | 1 |
Barnes, GE; Chandler, ML; Dean, T; Li, B | 1 |
Sall, K | 1 |
Amyot, M; Boisjoly, HM; Charest, M; Giasson, CJ; Lesk, MR; Nguyen, TQ | 1 |
Brubaker, RF; Ingram, CJ; Nau, CB; Schoff, EO | 1 |
Arend, O; Cantor, L; Chung, HS; Harris, A; Kagemann, L; Martin, B | 1 |
Connor, TB; Dev, S; Han, DP; Mieler, WF; Mittra, RA; Pollack, JS; Pulido, JS | 1 |
Nicolela, MT; Oga, E; Susanna, R | 1 |
Samuelson, TW; Simmons, ST | 1 |
O'Donoghue, EP | 1 |
Bucci, MG; Centofanti, M; Cocco, F; Gregori, D; Lorenzano, D; Manni, G | 1 |
Chopra, H; Day, DG; Holmes, KT; Kolker, AE; Konstas, AG; Lee, WH; Rieser, JC; Sharpe, ED; Stewart, WC | 1 |
Day, DG; Harbin, TS; Holmes, KT; Pastor, SA; Sharpe, ED; Stewart, JA; Stewart, WC | 1 |
Autelitano, A; Bottoli, A; Invernizzi, T; Orzalesi, N; Rossetti, L | 1 |
Kobayashi, M; Naito, K | 1 |
Bang, K; Dollerup, J; Eysteinsson, T; Jensen, PK; Kiilgaard, JF; la Cour, M; Stefánsson, E; Wiencke, AK | 1 |
Bjarnadóttir, G; Gudmundsdóttir, E; Gudmundsdóttir, G; Loftsson, T; Masson, M; Sigurjónsdóttir, JF; Stefánsson, E | 1 |
Bergua, A; Horn, FK; Jünemann, A; Korth, M; Velten, IM | 1 |
Barnebey, H; Kwok, SY | 1 |
Choudhri, S; Shields, MB; Wand, M | 1 |
Gagliuso, DJ; Podos, SM; Serle, JB; Wang, RF | 1 |
Gomez, ML; Honrubia, FM; Larrosa, JM; Pablo, L; Polo, V | 1 |
McClellan, K; Ormrod, D | 1 |
Herkel, U; Pfeiffer, N | 2 |
Rehůrek, J; Spicarová, R; Vancurová, J | 1 |
Aurilia, P; Boles Carenini, B; Durante, A; Guarnaccia, G | 1 |
Brogliatti, B; Cipullo, D; Rolle, T; Vizzeri, GM | 1 |
Hoshaw-Woodard, S; Robbin, TE; Schmall, ML; Wilkie, DA; Willis, AM | 1 |
Simmons, ST | 1 |
Findl, O; Georgopoulos, M; Kiss, B; Menapace, R; Petternel, V; Rainer, G | 1 |
Anielska, E; Czechowicz-Janicka, K; Dyczkowska, A; Orlewska, E; Tobota, Z | 1 |
Gelatt, KN; MacKay, EO | 1 |
Cawrse, MA; Hendrix, DV; Ward, DA | 1 |
Bernd, AS; Böhm, AG; Pillunat, LE; Richard, G; Schmidt, KG | 1 |
Friren, B; Michaud, JE | 1 |
Krueger, RR; Nagy, ZZ; Süveges, I; Szabó, A | 1 |
Potocký, M | 1 |
Andreanos, D; Dimitrakoulias, N; Kandarakis, A; Mylopoulos, N; Petounis, A | 1 |
Cole, C; Garzozi, H; Harris, A; Jonescu-Cuypers, CP; Kagemann, L; Martin, B; Nowacki, EA | 1 |
Jurkowska-Dudzińska, J; Kawa, P; Zagórski, Z; Zarnowski, T | 1 |
Dick, HB; Krummenauer, F; Schwenn, O; Xia, N | 1 |
Flammer, J; Gherghel, D; Gugleta, K; Orgül, S | 1 |
Banditt, P; Martens-Lobenhoffer, J | 1 |
Bergstrand, IC; Harris, A; Heijl, A | 1 |
El Sherbini, M; Flammer, J; Gekkieva, M; Haefliger, IO | 1 |
Easthope, SE; Perry, CM | 1 |
Martone, JF; Mead, A; O'Connor, DJ | 1 |
Avila, MY; Civan, MM; Seidler, RW; Stone, RA | 1 |
Dios Castro, E; Maquet Dusart, JA | 1 |
Halper, LK; Hartenbaum, D; Johnson-Pratt, L; Polis, A; Stewart, WC | 1 |
Stelzer, R; Wohlzogen, FX | 1 |
Camras, CB; Deasy, D; Framm, L; Lippa, EA; Lustgarten, J; Payne, JE; Podos, SM; Serle, JB | 1 |
Carlson, LE; Ehinger, B; Eriksson, LO; Finnström, K; Holmin, C; Lippa, EA; Nilsson, SE; Nyman, K; Raitta, C; Ringvold, A | 1 |
Gelatt, KN; Gum, GG; King, TC | 1 |
Béchetoille, A; Gerling, J; Grehn, F; Greve, E; Gunning, F; Jaquet-Müller, F; Lippa, EA; Pfeiffer, N | 1 |
Graham, SL; Hudcosky, RJ; Michelson, SR; Scholz, TH; Schwam, H; Shepard, KL; Smith, AM; Smith, RL; Sondey, JM; Strohmaier, KM | 1 |
Podos, SM; Serle, JB; Sugrue, MF; Wang, RF | 2 |
Aasved, H; Airaksinen, PJ; Alm, A; Bertelsen, T; Calissendorff, B; Dithmer, O; Eriksson, LO; Gustad, L; Høvding, G; Lippa, EA | 1 |
Bénichou, C; Bron, A; Clineschmidt, C; Flament, J; Gunning, F; Lesure, P; Lippa, EA; Panebianco, D; Royer, J; Sirbat, D | 1 |
Deasy, DA; Epstein, DL; Higginbotham, EJ; Holder, DJ; Kass, MA; Lippa, EA; Schuman, JS; Shaw, B; Skuta, GL; Weinreb, RN | 1 |
Brunner-Ferber, FL; Gerling, J; Grehn, F; Lippa, EA; Panebianco, D; Pfeiffer, N | 1 |
Brunner-Ferber, F; Gerling, J; Grehn, F; Lippa, E; Pfeiffer, N | 1 |
Gautheron, P; Graham, SL; Mallorga, P; Nolan, TE; Schwam, H; Shepard, KL; Smith, RL; Sugrue, MF | 1 |
Camras, CB; Lippa, EA; Lustgarten, JS; Panebianco, DL; Podos, SM; Serle, JB | 1 |
Garus, H; Grehn, F; Hennekes, R; Pfeiffer, N | 1 |
Brunner-Ferber, FL; Garus, H; Grehn, F; Hennekes, R; Lippa, EA; Pfeiffer, N | 1 |
Brunner-Ferber, F; Feicht, B; Hofmann, HM; Lippa, E; Merté, HJ; von Denffer, H | 1 |
Bar-Ilan, A; Brechue, WF; Conroy, CW; Maren, TH | 1 |
Podos, SM; Serle, JB; Surgrue, MF; Wang, RF | 1 |
Bechetoille, A; Brunner-Ferber, F; Diestelhorst, M; Krieglstein, GK; Lippa, E | 1 |
Baldwin, JJ; Christy, ME; Gautheron, P; Grove, J; Mallorga, P; Ponticello, GS; Schwam, H; Sugrue, MF; Viader, MP | 1 |
Batenhorst, RL; Higginbotham, EJ; Kass, MA; Lippa, EA; Panebianco, DL; Wilensky, JT | 1 |
Anderson, PS; Baldwin, JJ; Best, DB; Christy, ME; Freedman, MB; Gautheron, P; Graham, SL; Habecker, CN; Hoffman, JM; Shepard, KL | 1 |
Baldwin, JJ; Mallorga, P; Ponticello, GS; Schwam, H; Sugrue, MF | 1 |
Bron, AM; Brunner-Ferber, FL; Feicht, BI; Hofmann, HM; Lippa, EA; Panebianco, DL; Royer, JG; Von Denffer, HA | 1 |
Bar-Ilan, A; Maren, TH; Pessah, NI | 1 |
Kass, MA | 1 |
Brunner-Ferber, FL; Hofmann, HM; Lippa, EA; von Denffer, HA | 1 |
Gerber, DS; Werner, EB; Yoder, YJ | 1 |
Burke, JA; Chan, MF; Crosson, CE; Potter, DE | 1 |
39 review(s) available for thiophenes and Intraocular Pressure
Article | Year |
---|---|
The efficacy of the fixed combination of latanoprost and timolol versus other fixed combinations for primary open-angle glaucoma and ocular hypertension: A systematic review and meta-analysis.
Topics: Antihypertensive Agents; Bimatoprost; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2020 |
Dorzolamide/Timolol Fixed Combination: Learning from the Past and Looking Toward the Future.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2021 |
Anterior chamber fibrinoid syndrome after cataract extraction in a patient on ibrutinib for B-cell chronic lymphocytic leukemia: a case report and review of the literature.
Topics: Adenine; Administration, Topical; Aged; Anterior Chamber; Antihypertensive Agents; Antineoplastic Agents; Brimonidine Tartrate; Cataract Extraction; Humans; Intraocular Pressure; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Phacoemulsification; Piperidines; Prednisolone; Pyrazoles; Pyrimidines; Sulfonamides; Syndrome; Thiophenes; Timolol; Treatment Outcome; Visual Acuity | 2018 |
[Mode of action, clinical profile and relevance of carbonic anhydrase inhibitors in glaucoma therapy].
Topics: Animals; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Ciliary Body; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiazines; Thiophenes | 2013 |
Efficacy and tolerability of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure: a meta-analysis of randomized controlled trials.
Topics: Antihypertensive Agents; Drug Tolerance; Female; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2013 |
[Fixed combinations of glaucoma medications].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Drug Combinations; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2008 |
Efficacy and tolerability of latanoprost compared to dorzolamide combined with timolol in the treatment of patients with elevated intraocular pressure: a meta-analysis of randomized, controlled trials.
Topics: Antihypertensive Agents; Drug Combinations; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2009 |
[The role of Cosopt in glaucoma treatment].
Topics: Antihypertensive Agents; Drug Combinations; Evidence-Based Medicine; Glaucoma; Humans; Intraocular Pressure; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
Meta-analysis of medical intervention for normal tension glaucoma.
Topics: Aged; Amides; Antihypertensive Agents; Betaxolol; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Travoprost | 2009 |
Systematic review of intraocular pressure-lowering effects of adjunctive medications added to latanoprost.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Databases, Factual; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Optic Nerve Diseases; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Thiophenes; Timolol | 2009 |
WITHDRAWN: Interventions for normal tension glaucoma.
Topics: Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Vincamine | 2010 |
Fixed combinations of dorzolamide-timolol and brimonidine-timolol in the management of glaucoma.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Patient Selection; Quinoxalines; Risk Assessment; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2010 |
Meta-analysis of α2-adrenergic agonists versus carbonic anhydrase inhibitors as adjunctive therapy.
Topics: Adrenergic alpha-2 Receptor Agonists; Carbonic Anhydrase Inhibitors; Databases, Factual; Female; Humans; Intraocular Pressure; Male; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes | 2012 |
[Azarga, a new and useful fixed combination in glaucoma treatment].
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome; Vision, Ocular | 2011 |
[The latest developments in glaucoma therapy using fixed combination products].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate, Timolol Maleate Drug Combination; Carbonic Anhydrase Inhibitors; Cloprostenol; Drug Combinations; Drug Therapy, Combination; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2011 |
Efficacy and tolerability of fixed combination of brimonidine 0.2%/timolol 0.5% compared with fixed combination of dorzolamide 2%/timolol 0.5% in the treatment of patients with elevated intraocular pressure: a meta-analysis of randomized controlled trials
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Middle Aged; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2013 |
The effect of latanoprost on circadian intraocular pressure.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2002 |
Latanoprost versus combined timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2002 |
[Comparison of latanoprost monotherapy with timolol-dorzolamide combination in patients with open-angle glaucoma or ocular hypertension].
Topics: Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2002 |
An update on bimatoprost in glaucoma therapy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amides; Antihypertensive Agents; Benzimidazoles; Bimatoprost; Clinical Trials as Topic; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Omeprazole; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 2002 |
Four years later: a clinical update on latanoprost.
Topics: Antihypertensive Agents; Aqueous Humor; Blood Flow Velocity; Circadian Rhythm; Clinical Trials as Topic; Drug Therapy, Combination; Eye; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol | 2003 |
Interventions for normal tension glaucoma.
Topics: Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Vincamine | 2003 |
[Timolol topical ophthalmic combination].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Intraocular pressure-lowering effect of adding dorzolamide or latanoprost to timolol: a meta-analysis of randomized clinical trials.
Topics: Antihypertensive Agents; Databases, Factual; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2007 |
Efficacy and safety of brimonidine and dorzolamide for intraocular pressure lowering in glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Clinical Trials as Topic; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 2007 |
Meta-analysis of 24-hour intraocular pressure studies evaluating the efficacy of glaucoma medicines.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2008 |
A topical carbonic anhydrase inhibitor finally arrives.
Topics: Administration, Topical; Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1995 |
Trusopt, a topical carbonic anhydrase inhibitor.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1996 |
[Local carbonic anhydrase inhibitor dorzolamide: development and properties].
Topics: Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Glaucoma; Humans; Intraocular Pressure; Structure-Activity Relationship; Sulfonamides; Thiophenes | 1996 |
The preclinical pharmacology of dorzolamide hydrochloride, a topical carbonic anhydrase inhibitor.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Dogs; Drug Combinations; Drug Evaluation, Preclinical; Glaucoma; Intraocular Pressure; Macaca; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes; Timolol | 1996 |
New medical therapies for glaucoma.
Topics: Adrenergic alpha-Agonists; Carbonic Anhydrase Inhibitors; Clonidine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome | 1996 |
Dorzolamide. A review of its pharmacology and therapeutic potential in the management of glaucoma and ocular hypertension.
Topics: Absorption; Aging; Animals; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Controlled Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Quality of Life; Regional Blood Flow; Retina; Sulfonamides; Thiophenes; Tissue Distribution | 1997 |
[Trusopt--a new form of drug for treating glaucoma].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Drug Interactions; Drug Therapy, Combination; Glaucoma; Intraocular Pressure; Pilocarpine; Sulfonamides; Thiophenes | 1997 |
Beta-blocker-induced complications and the patient with glaucoma. Newer treatments to help reduce systemic adverse events.
Topics: Adrenergic beta-Antagonists; Brimonidine Tartrate; Cardiovascular System; Central Nervous System; Clonidine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Neurosecretory Systems; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Respiratory System; Sulfonamides; Thiophenes | 1998 |
[Pharmacological profiles of the potent carbonic anhydrase inhibitor dorzolamide hydrochloride, a topical antiglaucoma agent].
Topics: Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Eye; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes | 2000 |
Topical dorzolamide 2%/timolol 0.5%: a review of its use in the treatment of open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Timolol; Vision, Ocular | 2000 |
Update on topical carbonic anhydrase inhibitors.
Topics: Antihypertensive Agents; Aqueous Humor; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Eye; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes | 2001 |
Clinical pharmacokinetics of dorzolamide.
Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ciliary Body; Cornea; Erythrocytes; Glaucoma; Humans; Intraocular Pressure; Isoenzymes; Ophthalmic Solutions; Sulfonamides; Thiophenes | 2002 |
Topical bimatoprost: a review of its use in open-angle glaucoma and ocular hypertension.
Topics: Administration, Topical; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Conjunctival Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma, Open-Angle; Intraocular Pressure; Latanoprost; Lipids; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2002 |
239 trial(s) available for thiophenes and Intraocular Pressure
Article | Year |
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Comparing the effects and safety of dorzolamide hydrochloride + timolol maleate versus brimonidine after neodymium-doped yttrium aluminium garnet laser capsulotomy posterior capsule opacification.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Capsule Opacification; Glaucoma; Humans; Intraocular Pressure; Lasers, Solid-State; Neodymium; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Yttrium | 2022 |
Dilatation of Retinal Arterioles Induced by Topical Dorzolamide for One Week Is Impaired in Patients with Type 1 Diabetes and Mild Retinopathy.
Topics: Administration, Ophthalmic; Adult; Arterioles; Blood Pressure; Carbonic Anhydrase Inhibitors; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Homeostasis; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Vasodilation | 2020 |
The Glaucoma Italian Pediatric Study (GIPSy): The Long-term Effect of Topical Latanoprost on Central Corneal Thickness.
Topics: Administration, Topical; Adolescent; Age of Onset; Antihypertensive Agents; Child; Child, Preschool; Cornea; Corneal Pachymetry; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Italy; Latanoprost; Long-Term Care; Male; Organ Size; Sulfonamides; Thiophenes; Time Factors; Tonometry, Ocular | 2020 |
Effect of Adjuvant Topical Dorzolamide-Timolol vs Placebo in Neovascular Age-Related Macular Degeneration: A Randomized Clinical Trial.
Topics: Administration, Ophthalmic; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Chemotherapy, Adjuvant; Choroidal Neovascularization; Drug Combinations; Exudates and Transudates; Female; Humans; Intraocular Pressure; Intravitreal Injections; Macular Edema; Male; Ophthalmic Solutions; Placebos; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Visual Acuity; Wet Macular Degeneration | 2020 |
Additive effects and safety of fixed combination therapy with 1% brinzolamide and 0.5% timolol versus 1% dorzolamide and 0.5% timolol in prostaglandin-treated glaucoma patients.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Follow-Up Studies; Glaucoma, Open-Angle; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins, Synthetic; Sulfonamides; Thiazines; Thiophenes; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Dorzolamide nanoliposome as a long action ophthalmic delivery system in open angle glaucoma and ocular hypertension patients.
Topics: Antihypertensive Agents; Cornea; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Liposomes; Nanoparticles; Ocular Hypertension; Ophthalmic Solutions; Permeability; Sulfonamides; Thiophenes; Time Factors | 2018 |
The Glaucoma Italian Pediatric Study (GIPSy): 1-Year Results.
Topics: Antihypertensive Agents; Child; Child, Preschool; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Italy; Latanoprost; Male; Ocular Hypertension; Prognosis; Prospective Studies; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome | 2017 |
The Glaucoma Italian Pediatric Study (GIPSy): 3-Year Results.
Topics: Antihypertensive Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Italy; Latanoprost; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome | 2018 |
The effects of topical dorzolamide 2% and brinzolamide 1%, either alone or combined with timolol 0.5%, on intraocular pressure, pupil diameter, and heart rate in healthy cats.
Topics: Animals; Cats; Cross-Over Studies; Double-Blind Method; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; Intraocular Pressure; Male; Ophthalmic Solutions; Pupil; Sulfonamides; Thiazines; Thiophenes; Timolol | 2020 |
Effect of prophylactic intraocular pressure-lowering medication on pain during cataract surgery.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cataract; Cloprostenol; Combined Modality Therapy; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pain; Phacoemulsification; Postoperative Period; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Travoprost | 2013 |
Effects of dorzolamide-timolol and brimonidine-timolol on retinal vascular autoregulation and ocular perfusion pressure in primary open angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2013 |
Comparison of 24-hour intraocular pressure reduction obtained with brinzolamide/timolol or brimonidine/timolol fixed-combination adjunctive to travoprost therapy.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Cloprostenol; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol; Travoprost | 2013 |
The Heidelberg retina tomograph ancillary study to the European glaucoma prevention study: study design and baseline factors.
Topics: Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmoscopy; Optic Disk; Optic Nerve Diseases; Research Design; Sulfonamides; Thiophenes; Tomography; Tonometry, Ocular; Visual Acuity; Visual Fields | 2013 |
Comparison of dorzolamide/timolol versus brimonidine/timolol fixed combination therapy in the management of steroid-induced ocular hypertension.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Diabetic Retinopathy; Drug Combinations; Female; Glucocorticoids; Humans; Intraocular Pressure; Intravitreal Injections; Macular Edema; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Triamcinolone Acetonide | 2015 |
The safety and efficacy of brinzolamide 1%/timolol 0.5% fixed combination versus dorzolamide 2%/timolol 0.5% in patients with open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Preference; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 2013 |
γ-Cyclodextrin nanoparticle eye drops with dorzolamide: effect on intraocular pressure in man.
Topics: Carbonic Anhydrase Inhibitors; Cross-Over Studies; Drug Delivery Systems; Female; gamma-Cyclodextrins; Humans; Intraocular Pressure; Male; Nanoparticles; Ophthalmic Solutions; Pilot Projects; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes; Tonometry, Ocular; Visual Acuity | 2014 |
The effect of nebulized dorzolamide/timolol fixed combination mist versus drops on retrobulbar blood flow and intraocular pressure in glaucoma patients.
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Nebulizers and Vaporizers; Ophthalmic Solutions; Orbit; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2013 |
Effect of early treatment with aqueous suppressants on Ahmed glaucoma valve implantation outcomes.
Topics: Adult; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma; Glaucoma Drainage Implants; Humans; Intraocular Pressure; Logistic Models; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Acuity | 2014 |
Effect of topical aqueous suppression on intraocular gas duration after pure perfluoropropane injection in nonvitrectomized eyes with retinal detachment.
Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Aqueous Humor; Cryotherapy; Drug Combinations; Endotamponade; Fluorocarbons; Humans; Injections, Intraocular; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Prospective Studies; Retinal Detachment; Scleral Buckling; Sulfonamides; Thiophenes; Time Factors; Timolol; Vitrectomy | 2014 |
Effect of topical ophthalmic dorzolamide(2%)-timolol(0.5%) solution and ointment on intraocular pressure in normal horses.
Topics: Administration, Ophthalmic; Adrenergic beta-Antagonists; Animals; Drug Combinations; Female; Horses; Intraocular Pressure; Male; Ointments; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2015 |
Efficacy and tolerability of fixed-combination bimatoprost/timolol versus fixed-combination dorzolamide/brimonidine/timolol in patients with primary open-angle glaucoma or ocular hypertension: a multicenter, prospective, crossover study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Circadian Rhythm; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2014 |
Comparison of the Effects of Dorzolamide/Timolol Fixed Combination versus Latanoprost on Intraocular Pressure and Ocular Perfusion Pressure in Patients with Normal-Tension Glaucoma: A Randomized, Crossover Clinical Trial.
Topics: Blood Pressure; Circadian Rhythm; Cross-Over Studies; Demography; Diastole; Drug Combinations; Female; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Low Tension Glaucoma; Male; Middle Aged; Perfusion; Prostaglandins F, Synthetic; Sulfonamides; Systole; Thiophenes; Timolol | 2016 |
Brinzolamide/timolol versus dorzolamide/timolol fixed combinations: A hospital-based, prospective, randomized study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Egypt; Female; Glaucoma, Open-Angle; Hospitals, University; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular | 2016 |
Effects of a dorzolamide/timolol fixed combination on diurnal intraocular pressure, heart rate, blood pressure, and ocular perfusion pressure in normal-tension glaucoma.
Topics: Aged; Blood Pressure; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Gonioscopy; Heart Rate; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes; Time Factors; Timolol | 2016 |
Latanoprost and Dorzolamide for the Treatment of Pediatric Glaucoma: The Glaucoma Italian Pediatric Study (Gipsy), Design and Baseline Characteristics.
Topics: Antihypertensive Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Italy; Latanoprost; Male; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome | 2016 |
Comparison of dorzolamide/timolol vs brinzolamide/brimonidine fixed combination therapy in the management of primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Preventive Dorzolamide-Timolol for Rising Intraocular Pressure During Steep Trendelenburg Position Surgery.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Combinations; Eye; Female; Head-Down Tilt; Humans; Intraocular Pressure; Intraoperative Complications; Laparoscopy; Male; Middle Aged; Monitoring, Intraoperative; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2016 |
24-Hour Efficacy and Ocular Surface Health with Preservative-Free Tafluprost Alone and in Conjunction with Preservative-Free Dorzolamide/Timolol Fixed Combination in Open-Angle Glaucoma Patients Insufficiently Controlled with Preserved Latanoprost Monothe
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Prostaglandins F; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma.
Topics: Acetazolamide; Aged; Antihypertensive Agents; Dexamethasone; Drug Combinations; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preoperative Care; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Treatment Outcome | 2017 |
24-hour control of intraocular pressure with 2% dorzolamide/0.5% timolol fixed-combination ophthalmic solution in open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2008 |
Effects of dorzolamide 2% added to timolol maleate 0.5% on intraocular pressure, retrobulbar blood flow, and the progression of visual field damage in patients with primary open-angle glaucoma: a single-center, 4-year, open-label study.
Topics: Aged; Antihypertensive Agents; Disease Progression; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Orbit; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome; Visual Fields | 2008 |
Prolongation of activity of single intravitreal bevacizumab by adjuvant topical aqueous depressant (Timolol-Dorzolamide).
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Aqueous Humor; Bevacizumab; Diabetic Retinopathy; Drug Synergism; Drug Therapy, Combination; Female; Humans; Injections; Intraocular Pressure; Macular Edema; Male; Middle Aged; Retinal Vein Occlusion; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Acuity; Vitreous Body | 2009 |
Second-line therapy with dorzolamide/timolol or latanoprost/timolol fixed combination versus adding dorzolamide/timolol fixed combination to latanoprost monotherapy.
Topics: Antihypertensive Agents; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
A one-week comfort study of BID-dosed brinzolamide 1%/timolol 0.5% ophthalmic suspension fixed combination compared to BID-dosed dorzolamide 2%/timolol 0.5% ophthalmic solution in patients with open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol | 2008 |
An eight-week, multicentric, randomized, interventional, open-label, phase 4, parallel comparison of the efficacy and tolerability of the fixed combination of timolol maleate 0.5%/brimonidine tartrate 0.2% versus fixed combination of timolol maleate 0.5%/
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult | 2008 |
Efficacy and safety of latanoprost in eyes with uveitic glaucoma.
Topics: Adult; Antihypertensive Agents; Drug Combinations; Female; Follow-Up Studies; Glaucoma; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Recurrence; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Uveitis, Anterior; Uveitis, Intermediate; Visual Acuity | 2009 |
A comparison of the long-term effects of dorzolamide 2% and brinzolamide 1%, each added to timolol 0.5%, on retrobulbar hemodynamics and intraocular pressure in open-angle glaucoma patients.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiazines; Thiophenes; Timolol; Ultrasonography, Doppler, Color | 2009 |
Dorzolamide-timolol combination and retinal vessel oxygen saturation in patients with glaucoma or ocular hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Oximetry; Oxygen; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Young Adult | 2009 |
Three-month, randomized, parallel-group comparison of brimonidine-timolol versus dorzolamide-timolol fixed-combination therapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Osmolar Concentration; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol | 2009 |
Brimonidine tartrate 0.15%, dorzolamide hydrochloride 2%, and brinzolamide 1% compared as adjunctive therapy to prostaglandin analogs.
Topics: Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Single-Blind Method; Sulfonamides; Thiazines; Thiophenes; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Comparison of effects of topical levobunolol to a combination of timolol-dorzolamide on intraocular pressure and pulse rate of healthy dogs.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Dogs; Drug Combinations; Female; Heart Rate; Intraocular Pressure; Levobunolol; Male; Sulfonamides; Thiophenes; Timolol | 2009 |
Ocular blood flow and oxygen delivery to the retina in primary open-angle glaucoma patients: the addition of dorzolamide to timolol monotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Eye; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Middle Aged; Oximetry; Oxygen; Regional Blood Flow; Retina; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Ultrasonography, Doppler, Color | 2010 |
Predictors for visual field progression and the effects of treatment with dorzolamide 2% or brinzolamide 1% each added to timolol 0.5% in primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Disease Progression; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Proportional Hazards Models; Prospective Studies; Retinal Artery; Risk Factors; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography, Doppler, Color; Vision Disorders; Visual Fields | 2010 |
Effect of dorzolamide and timolol on ocular pressure: blood flow relationship in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Interferometry; Intraocular Pressure; Laser-Doppler Flowmetry; Lasers; Male; Middle Aged; Ocular Hypertension; Optic Disk; Optic Nerve Diseases; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2010 |
Efficacy and safety of fixed combinations of latanoprost/timolol and dorzolamide/timolol in open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 2010 |
Fixed-combination brimonidine/timolol as adjunctive therapy to a prostaglandin analog: a 3-month, open-label, replacement study in glaucoma patients.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Hypersensitivity; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol | 2009 |
Comparison of ocular hypotensive actions of fixed combinations of brimonidine/timolol and dorzolamide/timolol.
Topics: Aged; Aged, 80 and over; Algorithms; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Dosage Forms; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2010 |
Comparison of the efficacy and tolerability of preservative-free and preservative-containing formulations of the dorzolamide/timolol fixed combination (COSOPT™) in patients with elevated intraocular pressure in a randomized clinical trial.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2010 |
The additive effect of dorzolamide hydrochloride (Trusopt) and a morning dose of bimatoprost (Lumigan) on intraocular pressure and retrobulbar blood flow in patients with primary open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Blood Flow Velocity; Cloprostenol; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Ophthalmic Solutions; Orbit; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes | 2010 |
Comparison of the effects of dorzolamide/timolol and latanoprost/timolol fixed combinations upon intraocular pressure and progression of visual field damage in primary open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Disease Progression; Dosage Forms; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Fields | 2010 |
Effects of topical 0.5% levobunolol alone or in association with 2% dorzolamide compared with a fixed combination of 0.5% timolol and 2% dorzolamide on intraocular pressure and heart rate in dogs without glaucoma.
Topics: Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Dogs; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Heart Rate; Intraocular Pressure; Levobunolol; Male; Sulfonamides; Thiophenes; Timolol | 2010 |
Intraocular pressure and ocular hemodynamics in patients with primary open-angle glaucoma treated with the combination of morning dosing of bimatoprost and dorzolamide hydrochloride.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Blood Flow Velocity; Blood Pressure; Circadian Rhythm; Cloprostenol; Drug Administration Schedule; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ophthalmic Artery; Prospective Studies; Retinal Artery; Single-Blind Method; Sulfonamides; Thiophenes; Tonometry, Ocular; Ultrasonography, Doppler, Color | 2011 |
Intraocular pressure changes in the contralateral eye after topical treatment: does an "ophthalmotonic consensual reaction" exist?
Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cohort Studies; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins, Synthetic; Sulfonamides; Thiophenes; Timolol | 2010 |
[Comparative study of the pressure lowering efficacy and variations in the ocular pulse amplitude between fixed combinations of dorzolamide/timolol and brinzolamide/timolol].
Topics: Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Sectional Studies; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Pulse; Sulfonamides; Thiazines; Thiophenes; Timolol; Young Adult | 2011 |
From dorzolamide 2%/timolol 0.5% to brinzolamide 1%/timolol 0.5% fixed combination: a 6-month, multicenter, open-label tolerability switch study.
Topics: Aged; Antihypertensive Agents; Diagnostic Techniques, Ophthalmological; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Quality of Life; Sulfonamides; Surveys and Questionnaires; Thiazines; Thiophenes; Timolol | 2011 |
[Double-masked, phase III comparative study of the combination ophthalmic solution of the 1% dorzolamide hydrochloride/0.5% timolol maleate (MK-0507A) in patients with glaucoma and ocular hypertension].
Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2011 |
Pharmacodynamic equivalence study of two preparations of eye drops containing dorzolamide and timolol in healthy volunteers.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Eye Movements; Female; Fundus Oculi; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pupil; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Visual Acuity; Young Adult | 2011 |
Diurnal intraocular pressure efficacy of the timolol-brimonidine fixed combination and the timolol-dorzolamide fixed combination as a first choice therapy in patients with pseudoexfoliation glaucoma.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Administration Schedule; Drug Combinations; Exfoliation Syndrome; Female; Follow-Up Studies; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Single-Blind Method; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome; Visual Acuity | 2011 |
Twenty-four hour efficacy with the dorzolamide/timolol-fixed combination compared with the brimonidine/timolol-fixed combination in primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Medication Adherence; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 2012 |
Comparison of fixed combinations of dorzolamide/timolol and brimonidine/timolol in patients with primary open-angle glaucoma.
Topics: Aged; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Patient Compliance; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2011 |
Short-term effects of brimonidine/timolol and dorzolamide/timolol on ocular perfusion pressure and blood flow in glaucoma.
Topics: Administration, Ophthalmic; Aged; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2012 |
Comparison of dorzolamide/timolol and latanoprost/timolol fixed combinations on diurnal intraocular pressure control in primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Neuroprotective Agents; Optic Disk; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2012 |
Diurnal and nocturnal variations in aqueous humor dynamics of patients with ocular hypertension undergoing medical therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cornea; Cross-Over Studies; Double-Blind Method; Female; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sphygmomanometers; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography | 2012 |
A study of initial therapy for glaucoma in southern India: India Glaucoma Outcomes and Treatment (INGOT) Study.
Topics: Aged; Antihypertensive Agents; Antimetabolites, Antineoplastic; Brimonidine Tartrate; Drug Combinations; Female; Fluorouracil; Glaucoma; Humans; India; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Middle Aged; Phacoemulsification; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Tonometry, Ocular; Trabeculectomy; Visual Acuity | 2012 |
[Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections].
Topics: Acetazolamide; Aged; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Brimonidine Tartrate; Chemoprevention; Clonidine; Drug Combinations; Female; Humans; Hypotonic Solutions; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2012 |
Three-month evaluation of dorzolamide hydrochloride/timolol maleate fixed-combination eye drops versus the separate use of both drugs.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Medication Adherence; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Tonometry, Ocular | 2012 |
The European glaucoma prevention study design and baseline description of the participants.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Research Design; Safety; Sulfonamides; Thiophenes; Visual Acuity; Visual Field Tests; Visual Fields | 2002 |
Comparison of latanoprost, brimonidine and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2002 |
The short-term IOP-lowering effect of brimonidine 0.2% and dorzolomide 2% combination in primary open-angle glaucoma.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes | 2002 |
A comparison of the effects on intraocular pressure of latanoprost 0.005% and the fixed combination of dorzolamide 2% and timolol 0.5% in patients with open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2002 |
Timolol 0.5%/dorzolamide 2% fixed combination vs timolol maleate 0.5% and unoprostone 0.15% given twice daily to patients with primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cross-Over Studies; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Acuity | 2003 |
The efficacy and safety of the timolol/dorzolamide fixed combination vs latanoprost in exfoliation glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Patient Satisfaction; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol | 2003 |
Dorzolamide/timolol combination versus concomitant administration of brimonidine and timolol: six-month comparison of efficacy and tolerability.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 2003 |
Dorzolamide X apraclonidine in the prevention of the intraocular pressure spike after Nd : YAG laser posterior capsulotomy.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Clonidine; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Time Factors | 2002 |
The effect of latanoprost, brimonidine, and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2003 |
Unoprostone as adjunctive therapy to timolol: a double masked randomised study versus brimonidine and dorzolamide.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Chemotherapy, Adjuvant; Dinoprost; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2003 |
The effect of topical glaucoma medications evaluated by perimetry.
Topics: Administration, Topical; Antihypertensive Agents; Betaxolol; Clonidine; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Levobunolol; Prospective Studies; Sulfonamides; Thiophenes; Visual Field Tests | 2003 |
Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pilocarpine; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Twenty-four-hour diurnal curve comparison of commercially available latanoprost 0.005% versus the timolol and dorzolamide fixed combination.
Topics: Adult; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Replacing maximum-tolerated medications with latanoprost versus adding latanoprost to maximum-tolerated medications: a two-center randomized prospective trial.
Topics: Adrenergic beta-Antagonists; Aged; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Pilocarpine; Prostaglandins F, Synthetic; Retreatment; Single-Blind Method; Sulfonamides; Thiophenes | 2003 |
Evaluation of retinal haemodynamics and retinal function after application of dorzolamide, timolol and latanoprost in newly diagnosed open-angle glaucoma patients.
Topics: Adrenergic beta-Antagonists; Arteries; Blood Pressure; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Microscopy, Confocal; Middle Aged; Ophthalmoscopy; Prostaglandins F, Synthetic; Regional Blood Flow; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Veins | 2003 |
Effect of a fixed dorzolamide-timolol combination on intraocular pressure after small-incision cataract surgery with Viscoat.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Chondroitin; Chondroitin Sulfates; Double-Blind Method; Drug Combinations; Female; Humans; Hyaluronic Acid; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Time Factors; Timolol | 2003 |
A six-week, parallel, randomized, double-blind study comparing the efficacy and safety of the 0.5% timolol/2.0% MK-507 combination b.i.d. to the concomitant administration of 0.5% timolol b.i.d. and 2.0% MK-507 b.i.d.
Topics: Adult; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Statistics, Nonparametric; Sulfonamides; Thiophenes; Timolol | 2003 |
A 3-month randomized controlled trial of bimatoprost (LUMIGAN) versus combined timolol and dorzolamide (Cosopt) in patients with glaucoma or ocular hypertension.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol | 2003 |
The efficacy and safety of dose escalation of dorzolamide used in combination with other topical antiglaucoma agents.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Irritants; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins; Sulfonamides; Thiophenes; Time Factors | 2003 |
Aqueous humor flow in normal human eyes treated with brimonidine and dorzolamide, alone and in combination.
Topics: Administration, Topical; Adult; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Cornea; Double-Blind Method; Drug Therapy, Combination; Female; Fluorescein; Fluorophotometry; Humans; Intraocular Pressure; Male; Manometry; Middle Aged; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes | 2004 |
Efficacy and tolerability of the dorzolamide 2%/timolol 0.5% combination (COSOPT) versus 0.005% (XALATAN) in the treatment of ocular hypertension or glaucoma: results from two randomized clinical trials.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Efficacy and safety of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Dorzolamide/Timolol fixed combination versus concomitant administration of brimonidine and timolol in patients with elevated intraocular pressure: a 3-month comparison of efficacy, tolerability, and patient-reported measures.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Comparison of the safety and efficacy of dorzolamide 2% and brimonidine 0.2% in patients with glaucoma or ocular hypertension.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 2004 |
Effects on aqueous flow of dorzolamide combined with either timolol or acetazolamide.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Antihypertensive Agents; Aqueous Humor; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Manometry; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2004 |
[Efficiency of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers].
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quality of Life; Quinoxalines; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome | 2004 |
Immediate postoperative use of a topical agent to prevent intraocular pressure elevation after pars plana vitrectomy with gas tamponade.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Fluorocarbons; Humans; Intraocular Pressure; Male; Middle Aged; Postoperative Complications; Postoperative Period; Prospective Studies; Retinal Detachment; Retinal Perforations; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy | 2004 |
Brimonidine purite 0.15% versus dorzolamide 2% each given twice daily to reduce intraocular pressure in subjects with open angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes | 2004 |
Daytime diurnal curve comparison between the fixed combinations of latanoprost 0.005%/timolol maleate 0.5% and dorzolamide 2%/timolol maleate 0.5%.
Topics: Adult; Aged; Antihypertensive Agents; Chronotherapy; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2004 |
Comparison of latanoprost with fixed-combination dorzolamide and timolol in adult patients with elevated intraocular pressure: an eight-week, randomized, open-label, parallel-group, multicenter study in Latin America.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2004 |
Comparing the fixed combination dorzolamide-timolol (Cosopt) to concomitant administration of 2% dorzolamide (Trusopt) and 0.5% timolol -- a randomized controlled trial and a replacement study.
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2004 |
[Impact of prostaglandin-F(2alpha)-analogues and carbonic anhydrase inhibitors on central corneal thickness -- a cross-sectional study on 403 eyes].
Topics: Acetazolamide; Administration, Topical; Adult; Aged; Carbonic Anhydrase Inhibitors; Cloprostenol; Collagen; Cornea; Corneal Topography; Cross-Sectional Studies; Dinoprost; Drug Therapy, Combination; Extracellular Matrix; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Travoprost; Ultrasonography | 2004 |
Assessment of retinal hemodynamics with the Canon laser blood flowmeter after a single dose of 2% dorzolamide hydrochloride eyedrops.
Topics: Administration, Topical; Adult; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Female; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiophenes | 2004 |
[Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients].
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Pilocarpine; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
A comparison of the effects of dorzolamide/timolol fixed combination versus latanoprost on intraocular pressure and pulsatile ocular blood flow in primary open-angle glaucoma patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Flow Velocity; Cross-Over Studies; Drug Therapy, Combination; Eye; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Prostaglandins F, Synthetic; Pulsatile Flow; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography, Doppler | 2004 |
Two-year follow-up of latanoprost 0.005% monotherapy after changing from previous glaucoma therapies.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Germany; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 2004 |
Comparison of the efficacy and safety of dorzolamide 2% when added to brimonidine 0.2% or timolol maleate 0.5% in patients with primary open-angle glaucoma.
Topics: Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
Results of the European Glaucoma Prevention Study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Disease Progression; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quality Assurance, Health Care; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 2005 |
24-hour intraocular pressures with brimonidine purite versus dorzolamide added to latanoprost in primary open-angle glaucoma subjects.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Safety; Sulfonamides; Thiophenes; Visual Acuity | 2005 |
Effects of glaucoma drugs on ocular hemodynamics in normal tension glaucoma: a randomized trial comparing bimatoprost and latanoprost with dorzolamide [ISRCTN18873428].
Topics: Administration, Topical; Amides; Antihypertensive Agents; Bimatoprost; Blood Flow Velocity; Ciliary Arteries; Cloprostenol; Eye; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Latanoprost; Lipids; Ophthalmic Artery; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Regional Blood Flow; Retinal Artery; Single-Blind Method; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color | 2005 |
Dorzolamide influences the autoregulation of major retinal vessels caused by artificial intraocular pressure elevation in patients with POAG: a clinical study.
Topics: Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Female; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Muscle, Smooth, Vascular; Ocular Hypertension; Ophthalmic Solutions; Retinal Artery; Sulfonamides; Thiophenes; Vasodilation | 2005 |
The efficacy and safety of topical brinzolamide and dorzolamide when added to the combination therapy of latanoprost and a beta-blocker in patients with glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Instillation, Drug; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes; Treatment Outcome | 2005 |
Efficacy of the dorzolamide/timolol fixed combination versus latanoprost in the treatment of ocular hypertension or glaucoma: combined analysis of pooled data from two large randomized observer and patient-masked studies.
Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
Timolol/dorzolamide combination therapy as initial treatment for intraocular pressure over 30 mm Hg.
Topics: Adult; Antihypertensive Agents; Circadian Rhythm; Drug Combinations; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2005 |
A randomized trial assessing dorzolamide in patients with glaucoma who are younger than 6 years.
Topics: Antihypertensive Agents; Child, Preschool; Double-Blind Method; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
Effect of dorzolamide and timolol on ocular blood flow in patients with primary open angle glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Choroid; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Regional Blood Flow; Regression Analysis; Retinal Vessels; Sulfonamides; Thiophenes; Timolol | 2005 |
The efficacy and ocular discomfort of substituting brinzolamide for dorzolamide in combination therapy with latanoprost, timolol, and dorzolamide.
Topics: Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes; Timolol; Vision, Ocular | 2005 |
Comparison of latanoprost monotherapy and combined therapy of 0.5% timolol and 1% dorzolamide in chronic primary angle-closure glaucoma (CACG) in Japanese patients.
Topics: Aged; Antihypertensive Agents; Chronic Disease; Drug Combinations; Female; Glaucoma, Angle-Closure; Humans; Instillation, Drug; Intraocular Pressure; Japan; Latanoprost; Male; Ophthalmic Solutions; Patient Compliance; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2005 |
A comparison of the effects of 0.005% latanoprost and fixed combination dorzolamide/timolol on retrobulbar haemodynamics in previously untreated glaucoma patients.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Prostaglandins F, Synthetic; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2006 |
Comparative analysis of the effects of brimonidine and dorzolamide on ocular blood flow velocity in patients with newly diagnosed primary open-angle glaucoma.
Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Brimonidine Tartrate; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome; Ultrasonography, Doppler, Color | 2006 |
The effect of timolol-dorzolamide and timolol-pilocarpine combinations on ocular blood flow in patients with glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Ciliary Arteries; Cross-Over Studies; Drug Therapy, Combination; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Artery; Pilocarpine; Prospective Studies; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Ultrasonography, Doppler, Color | 2006 |
Effects of topical hypotensive drugs on circadian IOP, blood pressure, and calculated diastolic ocular perfusion pressure in patients with glaucoma.
Topics: Administration, Topical; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Circadian Rhythm; Diastole; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Perfusion; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2006 |
Additive effect of dorzolamide or carteolol to latanoprost in primary open-angle glaucoma: a prospective randomized crossover trial.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Carteolol; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome | 2006 |
Comparison of the efficacy and safety of travoprost with a fixed-combination of dorzolamide and timolol in patients with open-angle glaucoma or ocular hypertension.
Topics: Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Travoprost | 2006 |
Predictive factors for open-angle glaucoma among patients with ocular hypertension in the European Glaucoma Prevention Study.
Topics: Antihypertensive Agents; Disease Progression; Double-Blind Method; Europe; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prognosis; Proportional Hazards Models; Risk Factors; Sulfonamides; Thiophenes; Visual Acuity | 2007 |
A comparative analysis of the effects of the fixed combination of timolol and dorzolamide versus latanoprost plus timolol on ocular hemodynamics and visual function in patients with primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Cross-Over Studies; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Visual Acuity | 2006 |
Central corneal thickness in the European Glaucoma Prevention Study.
Topics: Adult; Age Factors; Aged; Cornea; Diabetes Complications; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sex Factors; Sulfonamides; Thiophenes; Ultrasonography | 2007 |
Circadian intraocular pressure control with dorzolamide versus timolol maleate add-on treatments in primary open-angle glaucoma patients using latanoprost.
Topics: Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2007 |
Comparison of the ocular hypotensive effects of bimatoprost and timolol-dorzolamide combination in patients with elevated intraocular pressure: a 6-month study.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes; Timolol | 2007 |
Retrobulbar haemodynamic effects of the latanoprost/timolol and the dorzolamide/timolol fixed combinations in newly diagnosed glaucoma patients.
Topics: Aged; Aged, 80 and over; Blood Flow Velocity; Ciliary Arteries; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Artery; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2007 |
Comparing the fixed combination brimonidine-timolol versus fixed combination dorzolamide-timolol in patients with elevated intraocular pressure.
Topics: Aged; Brimonidine Tartrate; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2007 |
A comparison of latanoprost monotherapy with a combination therapy of timolol/dorzolamide in patients with primary open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Drug Therapy, Combination; Eye Color; Eyelashes; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pain; Prostaglandins F, Synthetic; Pruritus; Sulfonamides; Thiophenes; Timolol | 2006 |
Intercurrent factors associated with the development of open-angle glaucoma in the European glaucoma prevention study.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Confidence Intervals; Cornea; Diuretics; Double-Blind Method; Europe; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Optic Disk; Prevalence; Proportional Hazards Models; Retinal Hemorrhage; Retrospective Studies; Risk Factors; Sulfonamides; Thiophenes; Time Factors; Treatment Outcome | 2007 |
Intraocular pressure rise after primary posterior continuous curvilinear capsulorhexis with a fixed dorzolamide-timolol combination: randomized safety study with intraindividual comparison using an angulated and a nonangulated intraocular lens.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Capsulorhexis; Cataract; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Middle Aged; Ocular Hypertension; Postoperative Complications; Prospective Studies; Prosthesis Design; Sulfonamides; Thiophenes; Timolol | 2007 |
Effect of dorzolamide hydrochloride on central corneal thickness in humans with cornea guttata.
Topics: Aged; Aged, 80 and over; Body Weights and Measures; Carbonic Anhydrase Inhibitors; Cell Count; Cornea; Corneal Diseases; Corneal Edema; Cross-Over Studies; Double-Blind Method; Endothelium, Corneal; Female; Humans; Interferometry; Intraocular Pressure; Light; Male; Middle Aged; Sulfonamides; Thiophenes; Tonometry, Ocular | 2007 |
Success rates for switching to dorzolamide/timolol fixed combination in timolol responders who are insufficiently controlled by latanoprost monotherapy.
Topics: Aged; Antihypertensive Agents; Cohort Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Satisfaction; Prospective Studies; Quality of Life; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Treatment Outcome | 2008 |
[Additive therapy with carboanhydrase inhibitors for open angle glaucoma previously treated with timolol 0.5% drops].
Topics: Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Sulfonamides; Thiazines; Thiophenes; Timolol | 2007 |
Comparison of the 24-hour intraocular pressure-lowering effects of latanoprost and dorzolamide/timolol fixed combination after 2 and 6 months of treatment.
Topics: Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Therapeutic Equivalency; Thiophenes; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2008 |
Comparison of the effects of dorzolamide-timolol fixed combination and brimonidine on intraocular pressure after phacoemulsification surgery.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Postoperative Care; Postoperative Complications; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
The effects of dorzolamide 2% and dorzolamide/timolol fixed combination on retinal and optic nerve head blood flow in primary open-angle glaucoma patients.
Topics: Aged; Analysis of Variance; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Optic Disk; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2008 |
Dorzolamide/timolol fixed combination versus latanoprost/timolol fixed combination in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2008 |
A comparative study of the effects of brinzolamide and dorzolamide on retinal oxygen saturation and ocular microcirculation in patients with primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Oxygen; Pilot Projects; Retinal Vessels; Sulfonamides; Thiazines; Thiophenes; Visual Acuity | 2008 |
Comparison of twice-daily and three-times-daily dosing of dorzolamide in ocular hypertension and primary open-angle glaucoma patients treated with latanoprost.
Topics: Antihypertensive Agents; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 2008 |
Effects of the timolol-dorzolamide fixed combination and latanoprost on circadian diastolic ocular perfusion pressure in glaucoma.
Topics: Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Diastole; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2008 |
A double-masked, randomized 1-year study comparing dorzolamide (Trusopt), timolol, and betaxolol. International Dorzolamide Study Group.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1995 |
Four-week safety and efficacy study of dorzolamide, a novel, active topical carbonic anhydrase inhibitor.
Topics: Administration, Topical; Adult; Aged; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Count; Cornea; Double-Blind Method; Drug Tolerance; Endothelium, Corneal; Erythrocytes; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes | 1993 |
A six-week dose-response study of the ocular hypotensive effect of dorzolamide with a one-year extension. Dorzolamide Dose-Response Study Group.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 1996 |
A controlled clinical trial of dorzolamide: a single-centre subset of a multicentre study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1996 |
The use of dorzolamide and pilocarpine as adjunctive therapy to timolol in patients with elevated intraocular pressure. The Dorzolamide Additivity Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Muscarinic Agonists; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Pilot Projects; Safety; Sulfonamides; Thiophenes; Timolol | 1996 |
Comparison of dorzolamide and acetazolamide as suppressors of aqueous humor flow in humans.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Female; Fluorescein; Fluoresceins; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1997 |
Effects of topical dorzolamide on retinal and retrobulbar hemodynamics.
Topics: Administration, Topical; Antihypertensive Agents; Blood Flow Velocity; Double-Blind Method; Fluorescein Angiography; Fundus Oculi; Humans; Image Processing, Computer-Assisted; Intraocular Pressure; Lasers; Ophthalmic Solutions; Ophthalmoscopes; Orbit; Reference Values; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color | 1996 |
A comparison of dorzolamide and timolol in patients with pseudoexfoliation and glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1997 |
A clinical trial of MK-507, Trusopt, for raised intraocular pressure--the Australian experience.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Australia; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1996 |
Effects of dorzolamide hydrochloride 2% on the retinal circulation.
Topics: Adult; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fundus Oculi; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiophenes | 1997 |
Central corneal thickness in normal, glaucomatous, and ocular hypertensive eyes.
Topics: Aged; Carbonic Anhydrase Inhibitors; Cornea; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular | 1997 |
Comparative effects of intraocular pressure between systemic and topical carbonic anhydrase inhibitors: a clinical masked, cross-over study.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Aging; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Eye Color; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1997 |
Topical 2.0% dorzolamide vs oral acetazolamide for prevention of intraocular pressure rise after neodymium:YAG laser posterior capsulotomy.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cataract Extraction; Double-Blind Method; Female; Follow-Up Studies; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Prospective Studies; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 1997 |
Comparison of dorzolamide and timolol as suppressors of aqueous humor flow in humans.
Topics: Adrenergic beta-Antagonists; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1997 |
Effect of dorzolamide on corneal endothelial function in normal human eyes.
Topics: Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Corneal Edema; Double-Blind Method; Endothelium, Corneal; Fluorescein; Fluorophotometry; Humans; Hypoxia; Intraocular Pressure; Microscopy; Middle Aged; Ophthalmic Solutions; Permeability; Sulfonamides; Thiophenes | 1998 |
Combination of systemic acetazolamide and topical dorzolamide in reducing intraocular pressure and aqueous humor formation.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular | 1998 |
Aqueous humor flow in human eyes treated with dorzolamide and different doses of acetazolamide.
Topics: Acetazolamide; Administration, Oral; Adult; Aqueous Humor; Bicarbonates; Carbonic Anhydrase Inhibitors; Contrast Media; Double-Blind Method; Drug Therapy, Combination; Eye; Female; Fluorescein; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Reference Values; Sulfonamides; Thiophenes | 1998 |
Dorzolamide hydrochloride and visual function in normal eyes.
Topics: Adult; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypercapnia; Hypocapnia; Intraocular Pressure; Male; Ophthalmic Solutions; Pilot Projects; Sulfonamides; Thiophenes; Visual Field Tests; Visual Fields | 1997 |
Hypotensive effects of dorzolamide eyewash in maximal therapy glaucoma patients: a comparative study with oral acetazolamide.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Treatment Outcome | 1997 |
A multicenter study comparing dorzolamide and pilocarpine as adjunctive therapy to timolol: patient preference and impact on daily life.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Quality of Life; Sulfonamides; Thiophenes; Timolol; Visual Fields | 1998 |
The effect of dorzolamide on aqueous humor dynamics in normal human subjects during sleep.
Topics: Administration, Topical; Adult; Anterior Eye Segment; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sleep; Sulfonamides; Thiophenes | 1998 |
A double-masked, randomized, 1-year study comparing the corneal effects of dorzolamide, timolol, and betaxolol. Dorzolamide Corneal Effects Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Cell Count; Double-Blind Method; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1998 |
Combined effect of dorzolamide and latanoprost on the rate of aqueous humor flow.
Topics: Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Uvea | 1998 |
Clinical efficacy and safety of brinzolamide (Azopt), a new topical carbonic anhydrase inhibitor for primary open-angle glaucoma and ocular hypertension. Brinzolamide Primary Therapy Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 1998 |
A trial of dorzolamide for glaucoma.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Child; Drug Administration Routes; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Sulfonamides; Thiophenes; Treatment Outcome | 1998 |
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide. Dorzolamide-Timolol Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components. Dorzolamide-Timolol Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide. Dorzolamide-Timolol Combination Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A comparison of the effectiveness of dorzolamide and acetazolamide in preventing post-operative intraocular pressure rise following phacoemulsification surgery.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Care; Prospective Studies; Sulfonamides; Thiophenes | 1998 |
Additive effect of dorzolamide on aqueous humor flow in patients receiving long-term treatment with timolol.
Topics: Adrenergic beta-Antagonists; Aged; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cohort Studies; Drug Synergism; Female; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 1998 |
Direct costs of glaucoma management following initiation of medical therapy. A simulation model based on an observational study of glaucoma treatment in Germany.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Germany; Glaucoma, Open-Angle; Humans; Insurance, Health, Reimbursement; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 1998 |
Two-year safety study of dorzolamide as monotherapy and with timolol and pilocarpine. Dorzolamide Safety Study Group.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A comparison of the efficacy and tolerability of dorzolamide and acetazolamide as adjunctive therapy to timolol. Oral to Topical CAI Study Group.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
Comparison of the safety and efficacy of the fixed combination of dorzolamide/timolol and the concomitant administration of dorzolamide and timolol: a clinical equivalence study. International Clinical Equivalence Study Group.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
Topical carbonic anhydrase inhibition increases ocular pulse amplitude in high tension primary open angle glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Cataract; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Placebos; Prospective Studies; Pulsatile Flow; Sulfonamides; Thiophenes | 1998 |
Clinical use of a topical carbonic anhydrase inhibitor in patients affected by chronic simple glaucoma.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Chronic Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Pilocarpine; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
[Postoperative behavior of intraocular pressure after posterior Nd:YAG laser capsulotomy--critical evaluation in preventive administration of local carbonic anhydrase II inhibitor dorzolamide hydrochloride (Trusopt)].
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cataract Extraction; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser Therapy; Male; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Premedication; Sulfonamides; Thiophenes; Treatment Outcome | 1998 |
Additive effect of latanoprost and dorzolamide in patients with elevated intraocular pressure.
Topics: Adult; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Exfoliation Syndrome; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Treatment Outcome | 1998 |
Dorzolamide effect on ocular blood flow.
Topics: Aged; Carbonic Anhydrase Inhibitors; Eye; Glaucoma; Hemodynamics; Humans; Intraocular Pressure; Middle Aged; Reference Values; Regional Blood Flow; Sulfonamides; Thiophenes; Ultrasonography | 1999 |
Effect of topical dorzolamide on optic nerve head blood flow.
Topics: Administration, Topical; Adult; Capillaries; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Optic Disk; Regional Blood Flow; Sulfonamides; Thiophenes; Time Factors | 1999 |
A randomized study of dorzolamide in the prevention of elevated intraocular pressure after anterior segment laser surgery. Dorzolamide Laser Study Group.
Topics: Anterior Eye Segment; Carbonic Anhydrase Inhibitors; Double-Blind Method; Humans; Intraocular Pressure; Laser Therapy; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Sulfonamides; Thiophenes | 1999 |
Effect of brinzolamide and dorzolamide on aqueous humor flow in human eyes.
Topics: Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Evaluation; Female; Fluorescein; Fluorophotometry; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiazines; Thiophenes | 1999 |
The dorzolamide/timolol combination versus timolol plus pilocarpine: patient preference and impact on daily life. United States Patient Preference Study Group. International Patient Preference Study Group.
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol | 1999 |
Topical versus oral carbonic anhydrase inhibitor therapy for pediatric glaucoma.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Cross-Over Studies; Female; Glaucoma; Humans; Intraocular Pressure; Male; Sulfonamides; Thiophenes | 1998 |
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1999 |
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 1999 |
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1999 |
Effect of dorzolamide and latanoprost on intraocular pressure after small incision cataract surgery.
Topics: Aged; Carbonic Anhydrase Inhibitors; Cataract Extraction; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Minimally Invasive Surgical Procedures; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Treatment Outcome | 1999 |
[Ocular pulse amplitude, intraocular pressure and beta blocker/carbonic anhydrase inhibition in combined therapy of primary open-angle glaucoma].
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pulsatile Flow; Sulfonamides; Thiophenes; Timolol | 1999 |
[The ocular hypotensive effect of the combination of latanoprost with dorzolamide].
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 1999 |
Comparison of latanoprost monotherapy to dorzolamide combined with timolol in patients with glaucoma and ocular hypertension.A 3-month randomised study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2000 |
The efficacy and safety of brinzolamide 1% ophthalmic suspension (Azopt) as a primary therapy in patients with open-angle glaucoma or ocular hypertension. Brinzolamide Primary Therapy Study Group.
Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Hypersensitivity; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Safety; Sulfonamides; Suspensions; Thiazines; Thiophenes; Treatment Outcome | 2000 |
Ocular comfort of brinzolamide 1.0% ophthalmic suspension compared with dorzolamide 2.0% ophthalmic solution: results from two multicenter comfort studies. Brinzolamide Comfort Study Group.
Topics: Adult; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Sulfonamides; Suspensions; Thiazines; Thiophenes; Treatment Outcome | 2000 |
Dorzolamide and corneal recovery from edema in patients with glaucoma or ocular hypertension.
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cell Count; Contact Lenses; Cornea; Corneal Edema; Double-Blind Method; Endothelium, Corneal; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Tonometry, Ocular | 2000 |
Comparison of the efficacy of betaxolol-brinzolamide and timolol-dorzolamide as suppressors of aqueous humor flow in human subjects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aqueous Humor; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular | 2000 |
A comparative study of betaxolol and dorzolamide effect on ocular circulation in normal-tension glaucoma patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Female; Fluorescein; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Ophthalmic Solutions; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color | 2000 |
The use of topical aqueous suppressants in the prevention of postoperative intraocular pressure elevation after pars plana vitrectomy with long-acting gas tamponade.
Topics: Administration, Topical; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Fluorocarbons; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy | 2000 |
Additive effect of latanoprost to the combination of timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2000 |
Comparison of brimonidine with latanoprost in the adjunctive treatment of glaucoma. ALPHAGAN/XALATAN Study Group.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Ocular Hypertension; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 2000 |
A comparison of latanoprost and dorzolamide in patients with glaucoma and ocular hypertension: a 3 month, randomised study. Ireland Latanoprost Study Group.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antihypertensive Agents; Circadian Rhythm; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes | 2000 |
Comparative acute effects of brimonidine 0.2% versus dorzolamide 2% combined with beta-blockers in glaucoma.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Tonometry, Ocular; Treatment Outcome | 2000 |
Brimonidine 0.2% versus dorzolamide 2% each given three times daily to reduce intraocular pressure.
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Treatment Outcome | 2000 |
Effect of timolol, latanoprost, and dorzolamide on circadian IOP in glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2000 |
Methazolamide 1% in cyclodextrin solution lowers IOP in human ocular hypertension.
Topics: Carbonic Anhydrase Inhibitors; Cyclodextrins; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Methazolamide; Ocular Hypertension; Ophthalmic Solutions; Pharmaceutical Vehicles; Sulfonamides; Thiophenes | 2000 |
Patients' acceptance of a switch from dorzolamide to brinzolamide for the treatment of glaucoma in a clinical practice setting.
Topics: Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Patient Satisfaction; Prospective Studies; Sulfonamides; Thiazines; Thiophenes | 2000 |
A comparison of dorzolamide-timolol combination versus the concomitant drugs.
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2000 |
Latanoprost versus combined therapy with timolol plus dorzolamide: IOP-lowering effect in open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2001 |
The hypotensive efficacy of dorzolamide HCL-timolol maleate 0.50% vs concomitant use of the two drugs.
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Therapeutic Equivalency; Thiophenes; Timolol | 2000 |
Comparison of the efficacy on intraocular pressure and retinal blood flow of a beta-blocker (timolol maleate) against the fixed association of a topical carbonic anhydrase (dorzolamide) and a beta-blocker (timolol maleate).
Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiophenes; Timolol | 2000 |
Hypotensive efficacy in primary open-angle glaucoma and ocular hypertension: latanoprost in monotherapy vs timolol and dorzolamide in association.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2000 |
Efficacy of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers in adult patients with glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Down-Regulation; Female; Glaucoma; Humans; Immunologic Factors; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quality of Life; Quinoxalines; Sulfonamides; Thiophenes | 2001 |
Intraindividual comparison of the effects of a fixed dorzolamide-timolol combination and latanoprost on intraocular pressure after small incision cataract surgery.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Middle Aged; Minimally Invasive Surgical Procedures; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2001 |
[Ocular hemodynamics and visual field in glaucoma treated with dorzolamide].
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Eye; Female; Follow-Up Studies; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiophenes; Visual Fields | 2001 |
Comparison of topical brinzolamide 1% and dorzolamide 2% eye drops given twice daily in addition to timolol 0.5% in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 2001 |
Treatment of intraocular pressure elevation after photorefractive keratectomy.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Fluorometholone; Glucocorticoids; Humans; Intraocular Pressure; Lasers, Excimer; Male; Ocular Hypertension; Ophthalmic Solutions; Photorefractive Keratectomy; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2001 |
Comparison of the additive intraocular pressure-lowering effect of latanoprost and dorzolamide when added to timolol in patients with open-angle glaucoma or ocular hypertension: a randomized, open-label, multicenter study in Greece.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Greece; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2001 |
Effect of dorzolamide timolol combination versus timolol 0.5% on ocular bloodflow in patients with primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Flow Velocity; Ciliary Arteries; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Eye; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Indocyanine Green; Intraocular Pressure; Laser-Doppler Flowmetry; Ophthalmic Artery; Ophthalmic Solutions; Ophthalmoscopy; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography; Visual Acuity | 2001 |
[Clinical evaluation of isopropyl unoprostone (Rescula), in the adjunctive treatment of primary open angle glaucoma].
Topics: Administration, Topical; Antihypertensive Agents; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2001 |
[Prevention of early postoperative increase in intraocular pressure after phacoemulsification. Comparison of different antiglaucoma drugs].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Middle Aged; Ophthalmic Solutions; Phacoemulsification; Polysaccharides, Bacterial; Postoperative Care; Postoperative Complications; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol | 2001 |
Retrobulbar blood flow in glaucoma patients with nocturnal over-dipping in systemic blood pressure.
Topics: Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Sectional Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ophthalmic Artery; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color | 2001 |
Dorzolamide and ocular blood flow in previously untreated glaucoma patients: a controlled double-masked study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Double-Blind Method; Eye; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Ophthalmic Solutions; Ophthalmoscopy; Retinal Artery; Sulfonamides; Thiophenes; Ultrasonography, Doppler, Color | 2002 |
Tolerability and efficacy of dorzolamide versus acetazolamide added to timolol.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 2002 |
Six week safety study of 2% MK-927 administered twice daily to ocular hypertensive volunteers.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Thiophenes; Timolol | 1992 |
Dose response and duration of action of dorzolamide, a topical carbonic anhydrase inhibitor.
Topics: Administration, Topical; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Placebos; Sulfonamides; Thiophenes | 1992 |
[Additive effect of timolol and the local carbonic anhydrase inhibitor MK-417 (sezolamide)].
Topics: Aged; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 1991 |
Multiple-dose, dose-response relationship for the topical carbonic anhydrase inhibitor MK-927.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Analysis of Variance; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Placebos; Sulfonamides; Thiophenes | 1991 |
Multiple-dose efficacy comparison of the two topical carbonic anhydrase inhibitors sezolamide and MK-927.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Stereoisomerism; Sulfonamides; Thiophenes | 1991 |
MK-507 versus sezolamide. Comparative efficacy of two topically active carbonic anhydrase inhibitors.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes | 1991 |
Comparative tolerability of topical carbonic anhydrase inhibitor MK-927 and its S-enantiomer MK-417.
Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Cornea; Double-Blind Method; Drug Tolerance; Humans; Intraocular Pressure; Male; Pupil; Stereoisomerism; Sulfonamides; Thiophenes | 1991 |
[Local carbonic anhydrase inhibitors MK-927 and Mk-417. Effect and tolerance].
Topics: Adult; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1990 |
MK-927, a topical carbonic anhydrase inhibitor. Dose response and reproducibility.
Topics: Administration, Topical; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Time Factors | 1990 |
[Decrease in intraocular pressure following administration of the local carbonic anhydrase inhibitor (MK-927)--comparison of the effect with pilocarpine].
Topics: Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes | 1990 |
A single dose of the topical carbonic anhydrase inhibitor MK-927 decreases IOP in patients.
Topics: Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes | 1990 |
[A new topical carbonic anhydrase inhibitor (MK-927). Tolerance comparison with betaxolol in healthy probands].
Topics: Administration, Topical; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Tolerance; Humans; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Time Factors | 1990 |
[Stereospecificity of lowering intraocular pressure using a locally administered carbonic anhydrase inhibitor].
Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Racemases and Epimerases; Sulfonamides; Thiophenes | 1990 |
MK-927: a topical carbonic anhydrase inhibitor. Dose response and duration of action.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Time Factors; Visual Acuity | 1990 |
MK-927: a topically effective carbonic anhydrase inhibitor in patients.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Double-Blind Method; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Placebos; Random Allocation; Sulfonamides; Thiophenes | 1989 |
Local tolerance and activity of MK-927, a novel topical carbonic anhydrase inhibitor.
Topics: Adult; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Double-Blind Method; Eye; Humans; Hyperemia; Intraocular Pressure; Male; Ophthalmic Solutions; Placebos; Random Allocation; Sulfonamides; Thiophenes | 1988 |
Effect of a topical carbonic anhydrase inhibitor, 6-hydroxybenzo[b]thiophene-2-sulfonamide, on intraocular pressure in normotensive subjects.
Topics: Adult; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Random Allocation; Sulfonamides; Thiophenes | 1987 |
175 other study(ies) available for thiophenes and Intraocular Pressure
Article | Year |
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Morphological changes in the trabecular meshwork and Schlemm's canal after treatment with topical intraocular pressure-lowering agents.
Topics: Administration, Topical; Drug Combinations; Humans; Intraocular Pressure; Middle Aged; Prostaglandins, Synthetic; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Trabecular Meshwork | 2021 |
Chitosan/hydroxyethyl cellulose inserts for sustained-release of dorzolamide for glaucoma treatment: In vitro and in vivo evaluation.
Topics: Animals; Cellulose; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Eye; Glaucoma; Intraocular Pressure; Male; Ophthalmic Solutions; Polymers; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Tissue Distribution | 2019 |
Comparison of Two Combinations of Maximum Medical Therapy for Lowering Intraocular Pressure in Primary Open-angle Glaucoma.
Topics: Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2020 |
Reversible Corneal Endothelial Abnormalities With Netarsudil.
Topics: Aged; Antihypertensive Agents; Benzoates; beta-Alanine; Corneal Diseases; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Remission Induction; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Withholding Treatment | 2020 |
Optical Coherence Tomography Angiography Vessel Density Changes in Normal-tension Glaucoma Treated With Carteolol, Brimonidine, or Dorzolamide.
Topics: Angiography; Brimonidine Tartrate; Carteolol; Female; Fluorescein Angiography; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Nerve Fibers; Retinal Ganglion Cells; Retinal Vessels; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Visual Fields | 2021 |
Forkhead domain inhibitory-6 attenuates subconjunctival fibrosis in rabbit model with trabeculectomy.
Topics: Actins; Animals; Blotting, Western; Cell Proliferation; Conjunctiva; Disease Models, Animal; Female; Fibroblasts; Fibronectins; Fibrosis; Forkhead Box Protein M1; Glaucoma; In Situ Nick-End Labeling; Injections, Intraocular; Intraocular Pressure; Male; Postoperative Complications; Pyridines; Rabbits; Real-Time Polymerase Chain Reaction; Tenon Capsule; Thiophenes; Trabeculectomy; Transforming Growth Factor beta1; Wound Healing | 2021 |
P16INK4a upregulation mediated by TBK1 induces retinal ganglion cell senescence in ischemic injury.
Topics: Animals; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Gene Knockdown Techniques; Intraocular Pressure; Ischemia; Models, Biological; Phosphorylation; Polycomb Repressive Complex 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; Retinal Ganglion Cells; RNA, Small Interfering; Signal Transduction; Thiophenes; Tumor Suppressor Protein p53; Up-Regulation | 2017 |
Isotretinoin-induced Angle Closure and Myopic Shift.
Topics: Acne Vulgaris; Adult; Antihypertensive Agents; Dermatologic Agents; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Isotretinoin; Microscopy, Acoustic; Myopia; Sulfonamides; Thiophenes; Timolol | 2017 |
Mirtogenol® supplementation in association with dorzolamide-timolol or latanoprost improves the retinal microcirculation in asymptomatic patients with increased ocular pressure.
Topics: Administration, Ophthalmic; Adult; Antihypertensive Agents; Blood Flow Velocity; Drug Combinations; Female; Flavonoids; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Microcirculation; Middle Aged; Oxidative Stress; Prostaglandins F, Synthetic; Retina; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2017 |
Eye Drop Dispenser Type and Medication Possession Ratio in Patients With Glaucoma: Single-Use Containers Versus Multiple-Use Bottles.
Topics: Administration, Ophthalmic; Aged; Antihypertensive Agents; Drug Combinations; Drug Packaging; Drug Utilization; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2018 |
Enhancement of pharmacokinetic and pharmacological behavior of ocular dorzolamide after factorial optimization of self-assembled nanostructures.
Topics: Animals; Aqueous Humor; Biological Availability; Delayed-Action Preparations; Drug Compounding; Glaucoma; Half-Life; Intraocular Pressure; Male; Nanostructures; Ophthalmic Solutions; Particle Size; Permeability; Phosphatidylcholines; Rabbits; Sulfonamides; Thiophenes | 2018 |
TOPICAL DORZOLAMIDE-TIMOLOL WITH INTRAVITREOUS ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR FOR RETINAL VEIN OCCLUSION: A PILOT STUDY.
Topics: Administration, Ophthalmic; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Bevacizumab; Drug Combinations; Drug Therapy, Combination; Female; Fovea Centralis; Humans; Intraocular Pressure; Intravitreal Injections; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Pilot Projects; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Retinal Vein Occlusion; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity | 2021 |
Sustained ocular delivery of Dorzolamide-HCl via proniosomal gel formulation: in-vitro characterization, statistical optimization, and in-vivo pharmacodynamic evaluation in rabbits.
Topics: Animals; Biological Availability; Chemistry, Pharmaceutical; Cholesterol; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Eye; Gels; Glaucoma; Intraocular Pressure; Liposomes; Male; Ophthalmic Solutions; Particle Size; Rabbits; Sulfonamides; Surface-Active Agents; Thiophenes | 2018 |
Acute angle closure following hemodialysis in a 34-year-old Nigerian female.
Topics: Adult; Drug Combinations; Female; Glaucoma; Glaucoma, Angle-Closure; Glomerulonephritis; Gonioscopy; Humans; Intraocular Pressure; Ophthalmic Solutions; Pilocarpine; Renal Dialysis; Renal Insufficiency, Chronic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Acuity | 2018 |
Is the Use of Refrigerated Fixed Combination of Dorzolamide 2%-Timolol 0.5% (COSOPT) Associated with Less Ocular Discomfort: A Pilot Study.
Topics: Antihypertensive Agents; Drug Combinations; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Pilot Projects; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2018 |
Consultation Section: Glaucoma. Management of cataract and glaucoma in patient with a preexisting Cypass microstent in fellow eye: January consultation #1.
Topics: Aged; Antihypertensive Agents; Cataract; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Optic Disk; Referral and Consultation; Retinal Pigment Epithelium; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Visual Fields | 2019 |
Designing of a pH-Triggered Carbopol®/HPMC In Situ Gel for Ocular Delivery of Dorzolamide HCl: In Vitro, In Vivo, and Ex Vivo Evaluation.
Topics: Acrylic Resins; Administration, Ophthalmic; Animals; Antihypertensive Agents; Cornea; Drug Carriers; Drug Evaluation, Preclinical; Drug Liberation; Gels; Glaucoma; Hydrogen-Ion Concentration; Hypromellose Derivatives; Intraocular Pressure; Male; Ophthalmic Solutions; Rabbits; Sulfonamides; Swine; Thiophenes | 2019 |
Effect of topical glaucoma medication on tear lipid layer thickness in patients with unilateral glaucoma.
Topics: Administration, Ophthalmic; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Cross-Sectional Studies; Drug Combinations; Dry Eye Syndromes; Female; Gonioscopy; Humans; Interferometry; Intraocular Pressure; Lipid Metabolism; Low Tension Glaucoma; Male; Meibomian Gland Dysfunction; Middle Aged; Ophthalmic Solutions; Sulfonamides; Tears; Thiophenes; Timolol; Tonometry, Ocular | 2019 |
Effect of Dorzolamide/Timolol or Brinzolamide/Timolol prophylaxis on intravitreal anti-VEGF injection-induced intraocular hypertension.
Topics: Administration, Topical; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Intravitreal Injections; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Ranibizumab; Retinal Diseases; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Vascular Endothelial Growth Factor A | 2013 |
Crystallins are regulated biomarkers for monitoring topical therapy of glaucomatous optic neuropathy.
Topics: Animals; Biomarkers; Crystallins; Disease Models, Animal; Drug Combinations; Gene Expression Profiling; Gene Expression Regulation; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Optic Nerve Diseases; Proteome; Proteomics; Rats; Real-Time Polymerase Chain Reaction; Retina; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Timolol | 2013 |
Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Caspase 3; Cell Count; Diminazene; Disease Models, Animal; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Glaucoma; Immunoenzyme Techniques; Intraocular Pressure; Male; Nerve Fibers; Ophthalmic Solutions; Optic Nerve; Peptide Fragments; Peptidyl-Dipeptidase A; Radionuclide Imaging; Rats; Rats, Wistar; Renin-Angiotensin System; Retina; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Tonometry, Ocular | 2013 |
[Contribution focused to clarify correlation between mixtures of the free amino acids with antiglaucomatics in influencing the IOP in rabbits after application into the conjunctival sac].
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol | 2013 |
A decrease of the rabbit's physiologic IOP after the application of specific amino acids and double combination of antiglaucomatics mixture.
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Taurine; Thiophenes; Timolol | 2013 |
Efficacy of prophylactic antiglaucoma and anti-inflammatory medications in canine primary angle-closure glaucoma: a multicenter retrospective study (2004-2012).
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cholinesterase Inhibitors; Dog Diseases; Dogs; Female; Glaucoma, Angle-Closure; Intraocular Pressure; Latanoprost; Male; Prostaglandins F, Synthetic; Quaternary Ammonium Compounds; Retrospective Studies; Sulfonamides; Thiophenes | 2014 |
[Signs and symptoms of ocular surface disease in patients on topical intraocular pressure-lowering therapy].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blepharitis; Cornea; Cross-Sectional Studies; Female; Fluorescein; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Keratitis; Lacrimal Apparatus Diseases; Male; Microscopy, Acoustic; Middle Aged; Ocular Hypertension; Severity of Illness Index; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Young Adult | 2013 |
Improvement in glaucoma patient quality of life by therapy switch to preservative-free timolol/dorzolamide fixed combination.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Drug Substitution; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Preservatives, Pharmaceutical; Prospective Studies; Quality of Life; Sickness Impact Profile; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Visual Acuity | 2014 |
Dorzolamide-loaded PLGA/vitamin E TPGS nanoparticles for glaucoma therapy: Pharmacoscintigraphy study and evaluation of extended ocular hypotensive effect in rabbits.
Topics: Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Intraocular Pressure; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Ocular Hypertension; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Radionuclide Imaging; Sulfonamides; Thiophenes; Vitamin A; Vitamin E | 2014 |
Anterior and posterior segment changes in rat eyes with chronic steroid administration and their responsiveness to antiglaucoma drugs.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Catalase; Dexamethasone; Disease Models, Animal; Female; Glutathione; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Oxidative Stress; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Rats, Sprague-Dawley; Retina; Sulfonamides; Superoxide Dismutase; Thiophenes; Timolol | 2015 |
Totally one-sided: painless unilateral proptosis.
Topics: Aged, 80 and over; Antihypertensive Agents; Arteriovenous Fistula; Brimonidine Tartrate; Carotid Artery, Internal; Cavernous Sinus; Cerebral Angiography; Diagnosis, Differential; Exophthalmos; Female; Humans; Intraocular Pressure; Levobunolol; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Tomography, X-Ray Computed; Treatment Outcome; Vision Disorders | 2015 |
Design, synthesis, and evaluation of NO-donor containing carbonic anhydrase inhibitors to lower intraocular pressure.
Topics: Animals; Carbonic Anhydrase Inhibitors; Drug Design; Glaucoma; Intraocular Pressure; Male; Nitric Oxide Donors; Rabbits; Sulfonamides; Thiazines; Thiophenes | 2015 |
Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action.
Topics: Animals; Antihypertensive Agents; Carbon Disulfide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Disease Models, Animal; Glaucoma; Humans; Intraocular Pressure; Male; Molecular Docking Simulation; Morpholines; Piperazines; Piperidines; Quinuclidines; Rabbits; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Thiocarbamates; Thiophenes | 2015 |
Retinal vein-to-vein anastomoses in Sturge-Weber syndrome documented by ultra-widefield fluorescein angiography.
Topics: Carbonic Anhydrase Inhibitors; Child; Fluorescein Angiography; Glaucoma; Humans; Intraocular Pressure; Male; Retinal Vein; Sturge-Weber Syndrome; Sulfonamides; Thiophenes; Vascular Fistula; Visual Acuity | 2015 |
Dual drug delivery from vitamin E loaded contact lenses for glaucoma therapy.
Topics: Animals; Antihypertensive Agents; Biological Availability; Contact Lenses; Delayed-Action Preparations; Dogs; Drug Liberation; Drug Therapy, Combination; Glaucoma, Open-Angle; Heart Rate; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Vitamin E | 2015 |
In Vitro Effects of Anti-Glaucomatous Eye Drops on Platelet-Activating Factor and its Metabolism.
Topics: Animals; Disease Models, Animal; Drug Combinations; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Platelet Activating Factor; Platelet Aggregation; Rabbits; Sulfonamides; Thiophenes; Timolol | 2017 |
The effect of prophylactic topical carbonic anhydrase inhibitors in canine primary closed-angle glaucoma.
Topics: Administration, Ophthalmic; Animals; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Intraocular Pressure; Male; Retrospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol | 2015 |
Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops.
Topics: Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2015 |
Secondary pigmentary glaucoma associated with 1-piece foldable intraocular lens in the ciliary sulcus.
Topics: Aged, 80 and over; Antihypertensive Agents; Ciliary Body; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Phacoemulsification; Prosthesis Design; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Tonometry, Ocular; Visual Acuity | 2015 |
Effects of Dorzolamide on Retinal and Choroidal Blood Flow in the DBA/2J Mouse Model of Glaucoma.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Choroid; Disease Models, Animal; Glaucoma; Intraocular Pressure; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Regional Blood Flow; Retina; Sulfonamides; Thiophenes; Treatment Outcome | 2016 |
Efficacy of Bimatoprost Plus Timolol Fixed Combination in Open Angle Glaucoma Patients Previously Treated with Dorzolamide Plus Timolol Fixed Combination.
Topics: Aged; Antihypertensive Agents; Bimatoprost; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 2016 |
In vitro and in vivo corneal effects of latanoprost combined with brimonidine, timolol, dorzolamide, or brinzolamide.
Topics: Animals; Brimonidine Tartrate; Cell Survival; Electric Impedance; Epithelium, Corneal; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Prostaglandins F, Synthetic; Rabbits; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol | 2016 |
Subconjunctival Delivery of Dorzolamide-Loaded Poly(ether-anhydride) Microparticles Produces Sustained Lowering of Intraocular Pressure in Rabbits.
Topics: Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Ethylamines; Female; Glaucoma; Intraocular Pressure; Lactic Acid; Male; Oleic Acid; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits; Sodium Dodecyl Sulfate; Sulfonamides; Thiophenes | 2016 |
Effect of prophylactic topical hypotensive medications in reducing the incidence of postoperative ocular hypertension after phacoemulsification in dogs.
Topics: Administration, Topical; Animals; Dog Diseases; Dogs; Female; Incidence; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Pre-Exposure Prophylaxis; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2017 |
Enhanced ocular efficacy of topically-delivered dorzolamide with nanostructured mucoadhesive microparticles.
Topics: Adhesives; Administration, Ophthalmic; Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Drug Compounding; Intraocular Pressure; Lactic Acid; Male; Mucous Membrane; Nanofibers; Ophthalmic Solutions; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Propylene Glycol; Rabbits; Solubility; Sulfonamides; Thiophenes | 2017 |
Recurrent serous macular detachment after topical ocular hypotensive medication.
Topics: Administration, Topical; Antihypertensive Agents; Clonidine; Drug Combinations; Drug Therapy, Combination; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Recurrence; Retinal Detachment; Serum; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Visual Acuity | 2008 |
Side effects of commonly used glaucoma medications: comparison of tolerability, chance of discontinuation, and patient satisfaction.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Patient Compliance; Patient Satisfaction; Prostaglandins F, Synthetic; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol | 2008 |
Additive effect of dorzolamide hydrochloride to patients taking travoprost: a retrospective study.
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cloprostenol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Follow-Up Studies; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Retrospective Studies; Sulfonamides; Thiophenes; Travoprost; Treatment Outcome; Visual Fields | 2008 |
[Intraocular pressure after instillation of amino acid arginine and combination of two antiglaucomatics (Trusopt + Xalatane mixture) in rabbits].
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Glaucoma; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes | 2008 |
Intraocular pressure lowering, change of antiapoptotic molecule expression, and neuroretinal changes by dorzolamide 2%/timolol 0.5% combination in a chronic ocular hypertension rat model.
Topics: Animals; bcl-X Protein; Cell Survival; Disease Models, Animal; Drug Combinations; Glial Fibrillary Acidic Protein; Intraocular Pressure; Male; Ocular Hypertension; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; RNA, Messenger; Sulfonamides; Thiophenes; Timolol | 2008 |
Effects of dorzolamide on choroidal blood flow, ciliary blood flow, and aqueous production in rabbits.
Topics: Administration, Topical; Animals; Aqueous Humor; Blood Flow Velocity; Blood Pressure; Carbonic Anhydrase Inhibitors; Choroid; Ciliary Body; Female; Fluorophotometry; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Rabbits; Regional Blood Flow; Sulfonamides; Thiophenes; Vasodilation | 2009 |
Relationship between visual field severity and response to fixed combination dorzolamide/timolol or timolol alone.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Linear Models; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Severity of Illness Index; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2009 |
Ocular pharmacokinetics and hypotensive activity of PF-04475270, an EP4 prostaglandin agonist in preclinical models.
Topics: Administration, Topical; Animals; Biological Availability; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Eye; Humans; Hydrolysis; Hyperemia; Intraocular Pressure; Models, Animal; Ophthalmic Solutions; Permeability; Prodrugs; Pyrrolidinones; Rabbits; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Transfection | 2009 |
Influence of various concentrations of terpene-4-ol enhancer and carbopol-934 mucoadhesive upon the in vitro ocular transport and the in vivo intraocular pressure lowering effects of dorzolamide ophthalmic formulations using albino rabbits.
Topics: Acrylates; Adhesives; Animals; Antihypertensive Agents; Biological Transport; Cornea; Dose-Response Relationship, Drug; Drug Compounding; Gels; In Vitro Techniques; Intraocular Pressure; Male; Mucous Membrane; Ophthalmic Solutions; Permeability; Rabbits; Sulfonamides; Terpenes; Thiophenes | 2010 |
Corneal thickness and glaucoma medications.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Cornea; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Relative efficacy of prostaglandins.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Pharmacokinetic-pharmacodynamic and response sensitization modeling of the intraocular pressure-lowering effect of the EP4 Agonist 5-{3-[(2S)-2-{(3R)-3-hydroxy-4-[3-(trifluoromethyl)phenyl]butyl}-5-oxopyrrolidin-1-yl]propyl}thiophene-2-carboxylate (PF-044
Topics: Algorithms; Animals; Aqueous Humor; Ciliary Body; Dogs; Female; Glaucoma; Humans; Intraocular Pressure; Male; Models, Statistical; Ocular Hypertension; Prodrugs; Pyrrolidinones; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes | 2009 |
Choroidal detachment in association with topical dorzolamide: is hypotony always the cause?
Topics: Aged; Antihypertensive Agents; Choroid Diseases; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Visual Acuity | 2009 |
Retinal arteriolar vascular reactivity in untreated and progressive primary open-angle glaucoma.
Topics: Administration, Topical; Aged; Arterioles; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Disease Progression; Glaucoma, Open-Angle; Humans; Hypercapnia; Intraocular Pressure; Laser-Doppler Flowmetry; Middle Aged; Optic Disk; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes | 2010 |
Corneal neovascularization and ocular irritancy responses in dogs following topical ocular administration of an EP4-prostaglandin E2 agonist.
Topics: Administration, Topical; Animals; Cornea; Corneal Neovascularization; Dogs; Drug Combinations; Eye; Factor VIII; Intraocular Pressure; Pyrrolidinones; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Toxicity Tests; von Willebrand Factor | 2009 |
Efficacy of sustained topical dorzolamide therapy for cystic macular lesions in patients with X-linked retinoschisis.
Topics: Administration, Topical; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Eye Proteins; Follow-Up Studies; Humans; Intraocular Pressure; Macular Edema; Middle Aged; Ophthalmic Solutions; Retinoschisis; Retrospective Studies; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Young Adult | 2010 |
Benzothiophene containing Rho kinase inhibitors: Efficacy in an animal model of glaucoma.
Topics: Animals; Disease Models, Animal; Glaucoma; Haplorhini; HeLa Cells; Humans; Intraocular Pressure; Ocular Hypertension; Protein Kinase Inhibitors; rho-Associated Kinases; Thiophenes | 2010 |
Effectiveness of dorzolamide–timolol (COSOPT) in patients who were treatment naive for open-angle glaucoma or ocular hypertension: the COSOPT first-line study.
Topics: Aged; Drug Combinations; Eye; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2010 |
Efficacy and tolerability of preservative-free eye drops containing a fixed combination of dorzolamide and timolol in glaucoma patients.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Benzalkonium Compounds; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Male; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2010 |
The clinical impact of 2 different strategies for initiating therapy in patients with ocular hypertension.
Topics: Adult; Antihypertensive Agents; Blindness; Brimonidine Tartrate; Decision Trees; Disease Progression; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Models, Biological; Monte Carlo Method; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Risk Assessment; Sulfonamides; Thiophenes; Timolol | 2011 |
S1P₂ receptor regulation of sphingosine-1-phosphate effects on conventional outflow physiology.
Topics: Animals; Aqueous Humor; Cells, Cultured; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lysophospholipids; Myosin Light Chains; Oxadiazoles; Phosphorylation; Pyrazoles; Pyridines; Receptors, Lysosphingolipid; Sphingosine; Swine; Thiophenes; Trabecular Meshwork | 2011 |
[Comparison of primary medicament therapy effects and primary argon laser trabeculoplasty on regulation of intraocular pressure and stability of perimetry findings in open angle glaucoma].
Topics: Aged; Antihypertensive Agents; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Lasers, Gas; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Visual Field Tests | 2011 |
In vitro and in vivo evaluation of an intraocular implant for glaucoma treatment.
Topics: Animals; Antihypertensive Agents; Calorimetry, Differential Scanning; Drug Carriers; Drug Implants; Eye; Glaucoma; Intraocular Pressure; Kinetics; Microscopy, Electron, Scanning; Polyesters; Polyethylene Glycols; Propylene Glycols; Rabbits; Solubility; Sulfonamides; Surface Properties; Thiophenes | 2011 |
Comparison of selective laser trabeculoplasty success in patients treated with either prostaglandin or timolol/dorzolamide fixed combination.
Topics: Aged; Antihypertensive Agents; Drug Combinations; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Prostaglandins, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Treatment Outcome | 2011 |
The effect of dorzolamide 2% on circadian intraocular pressure in cats with primary congenital glaucoma.
Topics: Administration, Ophthalmic; Animals; Carbonic Anhydrase Inhibitors; Cat Diseases; Cats; Circadian Rhythm; Female; Glaucoma; Intraocular Pressure; Male; Sulfonamides; Thiophenes | 2011 |
The long-term outcomes of four alternative treatment strategies for primary open-angle glaucoma.
Topics: Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Cost-Benefit Analysis; Decision Support Techniques; Disease Progression; Drug Costs; Economics, Pharmaceutical; Follow-Up Studies; Glaucoma, Open-Angle; Health Care Costs; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quality-Adjusted Life Years; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2012 |
The effects of a fixed combination of 0.5% timolol and 1% dorzolamide on optic nerve head blood circulation.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Synergism; Eye; Female; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Optic Disk; Perfusion; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Young Adult | 2012 |
Retrobulbar hemodynamics before and after oculopression with and without dorzolamide.
Topics: Administration, Topical; Aged; Blood Flow Velocity; Blood Pressure; Carbonic Anhydrase Inhibitors; Female; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Orbit; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiophenes; Tonometry, Ocular; Ultrasonography, Doppler, Color | 2012 |
Resolution of bilateral ptosis after reduction of unilaterally elevated intraocular pressure in a child with Axenfeld-Reiger spectrum disorder.
Topics: Anterior Eye Segment; Antihypertensive Agents; Blepharoptosis; Drug Combinations; Eye Abnormalities; Eye Diseases, Hereditary; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2012 |
Effects of ocular administration of ophthalmic 2% dorzolamide hydrochloride solution on aqueous humor flow rate and intraocular pressure in clinically normal cats.
Topics: Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cats; Female; Fluorophotometry; Intraocular Pressure; Linear Models; Male; Ophthalmic Solutions; Random Allocation; Sulfonamides; Thiophenes; Tonometry, Ocular | 2012 |
Regulation of retinal proteome by topical antiglaucomatous eye drops in an inherited glaucoma rat model.
Topics: Animals; Calmodulin; Carbonic Anhydrase II; Cloprostenol; Disease Models, Animal; Glaucoma; HMGB1 Protein; HSP70 Heat-Shock Proteins; Intraocular Pressure; Ophthalmic Solutions; Peptide Mapping; Proteome; Proteomics; Rats; Retina; Sulfonamides; Thiophenes; Travoprost | 2012 |
[The rabbit's IOP values after instillation of the L-arginine HCL with selected antiglaucomatic drugs mixtures prepared in vitro. (comparative study of results of the experimental works)].
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol | 2012 |
Congenital glaucoma with acquired peripheral circumferential iris degeneration.
Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1B1; Drug Therapy, Combination; Eye Abnormalities; Female; Forkhead Transcription Factors; Humans; Hydrophthalmos; Infant; Intraocular Pressure; Iris; Point Mutation; Sequence Deletion; Sulfonamides; Thiophenes; Timolol | 2013 |
The pulsatile ocular blood flow behaviour in open angle glaucoma patients after replacing timolol therapy with timolol and dorzolamide fixed combination: preliminary study.
Topics: Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Pulsatile Flow; Sulfonamides; Thiophenes; Timolol | 2002 |
Functional analysis of retinal vessel diameter reaction to artificially raised intraocular pressure in glaucoma patients with and without dorzolamide therapy.
Topics: Adult; Aged; Antihypertensive Agents; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Retinal Vessels; Sulfonamides; Thiophenes; Vascular Resistance | 2002 |
[Glaucoma: an ocular blood flow disorder?].
Topics: Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Rheology; Risk Factors; Sulfonamides; Thiophenes; Time Factors; Timolol | 2003 |
Experience with COSOPT, the fixed combination of timolol and dorzolamide, gained in Swiss ophthalmologists' offices.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Child; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Neuroprotective Agents; Physicians' Offices; Practice Patterns, Physicians'; Prostaglandins F, Synthetic; Sulfonamides; Switzerland; Thiophenes; Timolol; Treatment Outcome | 2003 |
Effects of twice daily application of 2% dorzolamide on intraocular pressure in normal cats.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Cats; Female; Intraocular Pressure; Male; Ophthalmic Solutions; Reference Values; Sulfonamides; Thiophenes; Tonometry, Ocular | 2003 |
Comparison of the efficacy of the fixed-combination timolol/dorzolamide versus concomitant administration of timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Aged; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Experience with Cosopt, the fixed combination of timolol and dorzolamide, after switch from free combination of timolol and dorzolamide, in Swiss ophthalmologists' offices.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cluster Analysis; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Ophthalmology; Sulfonamides; Switzerland; Thiophenes; Timolol | 2003 |
Patient persistency with pharmacotherapy in the management of glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Cohort Studies; Drug Utilization; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypertension; Patient Compliance; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes | 2003 |
Switching from systemic to the topical carbonic anhydrase inhibitor dorzolamide: effect on the quality of life of glaucoma patients with drug-related side effects.
Topics: Aged; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Glaucoma, Open-Angle; Health Status Indicators; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quality of Life; Sulfonamides; Thiophenes | 2003 |
[Effects of ocular hypotensive agents on the circadian rhythm in intraocular pressure in rabbits as measured by telemetry].
Topics: Animals; Circadian Rhythm; Intraocular Pressure; Male; Quinazolines; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol | 2003 |
Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide.
Topics: Administration, Topical; Animals; Benzolamide; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Cattle; Esters; Glaucoma; Humans; Intraocular Pressure; Rabbits; Structure-Activity Relationship; Sulfonamides; Thiazines; Thiophenes | 2003 |
Optic nerve oxygen tension: the effects of timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Drug Interactions; Heart Rate; Intraocular Pressure; Optic Disk; Oxygen; Partial Pressure; Sulfonamides; Swine; Thiophenes; Timolol | 2004 |
Ocular blood flow and systemic blood pressure in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Pulsatile Flow; Regional Blood Flow; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2004 |
A novel neuroprotectant against retinal ganglion cell damage in a glaucoma model and an optic nerve crush model in the rat.
Topics: Animals; Cell Count; Cell Death; Cell Survival; Diethylamines; Disease Models, Animal; Intraocular Pressure; Male; Nerve Crush; Neuroprotective Agents; Ocular Hypertension; Optic Nerve; Optic Nerve Diseases; Rats; Rats, Wistar; Retinal Ganglion Cells; Thiophenes | 2004 |
Is addition of a third or fourth antiglaucoma medication effective?
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Prostaglandins; Retrospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
[Intraocular pressure in rabbits after administration of 10% L-arginine HCl in 2% Trusopt].
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Pupil; Rabbits; Sulfonamides; Thiophenes | 2004 |
[Comparison of the effectiveness of a mixture of 10% L-arginine and HCl combined with 0.5% Timoptol and with 2% Trusopt: and the individual components on intraocular pressure in an experiment on rabbits].
Topics: Animals; Antihypertensive Agents; Arginine; Carbonic Anhydrase Inhibitors; Drug Combinations; Intraocular Pressure; Male; Rabbits; Sulfonamides; Thiophenes; Timolol | 2004 |
[Neuroprotection and vasoprotection in glaucoma].
Topics: Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Carteolol; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Neuroprotective Agents; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Treatment Outcome | 2004 |
[Measurement of corneal thickness in cases where tonometry is contraindicated].
Topics: Antihypertensive Agents; Computer Graphics; Corneal Topography; Diagnosis, Differential; Drug Combinations; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Manometry; Middle Aged; Optic Disk; Prostaglandins F, Synthetic; Signal Processing, Computer-Assisted; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2004 |
Bimatoprost versus timolol and dorzolamide.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Lipids; Ocular Hypertension; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2005 |
The effect of combination pharmacotherapy on the prescription trends of glaucoma medications.
Topics: Antihypertensive Agents; Drug Combinations; Drug Prescriptions; Drug Utilization; Glaucoma, Open-Angle; Health Maintenance Organizations; Health Services Research; Health Surveys; Humans; Intraocular Pressure; Israel; Ocular Hypertension; Practice Patterns, Physicians'; Sulfonamides; Thiophenes; Timolol | 2005 |
Topically administered timolol and dorzolamide reduce intraocular pressure and protect retinal ganglion cells in a rat experimental glaucoma model.
Topics: Animals; Antihypertensive Agents; Cell Count; Cell Survival; Cytoprotection; Disease Models, Animal; Glaucoma; Intraocular Pressure; Male; Ophthalmic Solutions; Rats; Rats, Wistar; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Timolol | 2005 |
[IOP in rabbits after instillation of a mixture of the antiglaucomatic Cosopt and the aminoacid L-argininin HCL into the conjunctival sac].
Topics: Animals; Arginine; Drug Combinations; Female; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes; Timolol | 2005 |
European Glaucoma Prevention Study.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Europe; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiophenes | 2005 |
Dorzolamide and timolol saves retinal ganglion cells in glaucomatous adult rats.
Topics: Animals; Antihypertensive Agents; Cell Count; Disease Models, Animal; Drug Combinations; Female; Glaucoma; Intraocular Pressure; Pilot Projects; Rats; Rats, Wistar; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Time Factors; Timolol | 2005 |
[Intraocular pressure after ND: YAG laser capsulotomy in pseudophakic patients with glaucoma].
Topics: Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Cataract Extraction; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Preoperative Care; Pseudophakia; Quinoxalines; Sulfonamides; Thiophenes | 2006 |
Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs.
Topics: Administration, Topical; Aged; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Carteolol; Case-Control Studies; Chemokines; Cloprostenol; Cytokines; Dose-Response Relationship, Immunologic; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Tears; Thiophenes; Timolol | 2007 |
Effect of 2% dorzolamide on retinal blood flow: a study on juvenile primary open-angle glaucoma patients already receiving 0.5% timolol.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Drug Interactions; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2007 |
Brimonidine/Timolol: a viewpoint by Francisco J. Goñi.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2006 |
The additive effect of topical dorzolamide and systemic acetazolamide in pediatric glaucoma.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adolescent; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Retrospective Studies; Sulfonamides; Thiophenes; Tonometry, Ocular | 2006 |
Anosmia as an adverse effect of dorzolamid.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Olfaction Disorders; Sulfonamides; Thiophenes | 2007 |
[Case of pigmentary glaucoma treated with medical therapy, laser treatment, and trabeculotomy].
Topics: Adrenergic alpha-Antagonists; Adult; Antihypertensive Agents; Argon; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Ophthalmic Solutions; Quinazolines; Sulfonamides; Thiophenes; Trabeculectomy; Treatment Outcome | 2007 |
Intraocular pressure lowering effect of dorzolamide/timolol fixed combination in patients with glaucoma who were unresponsive to prostaglandin analogs/prostamides.
Topics: Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Probability; Prostaglandins, Synthetic; Retrospective Studies; Severity of Illness Index; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Failure; Treatment Outcome | 2007 |
Hypotony and choroidal detachment as a complication of topical combined timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cataract Extraction; Choroid Diseases; Chronic Disease; Drug Interactions; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Recurrence; Sulfonamides; Thiophenes; Timolol; Trabeculectomy | 2007 |
Hypotensive effect of profilin on rabbit intraocular pressure.
Topics: Animals; Antihypertensive Agents; Intraocular Pressure; Latanoprost; Pilocarpine; Profilins; Prostaglandins F, Synthetic; Protein Structure, Tertiary; Rabbits; Recombinant Fusion Proteins; Sulfonamides; Thiophenes | 2007 |
Diuretics, placebos, and the European glaucoma prevention study.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Diuretics; Europe; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Optic Disk; Prevalence; Randomized Controlled Trials as Topic; Retinal Hemorrhage; Risk Factors; Sulfonamides; Thiophenes | 2007 |
Intercurrent factors associated with the development of open-angle glaucoma in the European glaucoma prevention study.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Diabetes Complications; Europe; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Prevalence; Risk Factors; Sulfonamides; Thiophenes; Treatment Outcome | 2008 |
Estimation of ocular rigidity based on measurement of pulse amplitude using pneumotonometry and fundus pulse using laser interferometry in glaucoma.
Topics: Aged; Blood Pressure; Drug Therapy, Combination; Female; Fundus Oculi; Glaucoma, Open-Angle; Humans; Interferometry; Intraocular Pressure; Lasers; Latanoprost; Light; Male; Middle Aged; Prostaglandins F, Synthetic; Pulse; Reference Values; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2008 |
[The time required topical carbonic anhydrase inhibitor (MK-507) to take effect on intraocular pressure of normal human eyes].
Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Depression, Chemical; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Time Factors | 1995 |
Effect of MK-507 on aqueous humor dynamics in normal human eyes.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Eye Proteins; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1994 |
[Effect of topical carbonic anhydrase inhibitor (MK-507) on intraocular pressure of normal human eyes].
Topics: Acetazolamide; Administration, Topical; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Depression, Chemical; Eye Proteins; Humans; Intraocular Pressure; Sulfonamides; Thiophenes | 1994 |
pH and drug ionization affects ocular pressure lowering of topical carbonic anhydrase inhibitors.
Topics: Animals; Carbonic Anhydrase Inhibitors; Eye; Hydrogen-Ion Concentration; Imidazoles; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Osmolar Concentration; Rabbits; Solubility; Sulfonamides; Thiophenes | 1993 |
A comparison between the effect of topical and systemic carbonic anhydrase inhibitors on aqueous humor secretion.
Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ethoxzolamide; Injections, Intravenous; Intraocular Pressure; Male; Methazolamide; Rabbits; Sulfonamides; Thiophenes; Time Factors; Uvea | 1993 |
Carbonic anhydrase inhibitory activity and ocular pharmacology of organic sulfamates.
Topics: Animals; Carbonic Anhydrase Inhibitors; Eye; Hydrogen-Ion Concentration; Imidazoles; Intraocular Pressure; Rabbits; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids; Thiophenes | 1993 |
Topical dorzolamide-induced hypotony and ciliochoroidal detachment in patients with previous filtration surgery.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Choroid Diseases; Ciliary Body; Female; Filtering Surgery; Glaucoma; Humans; Intraocular Pressure; Ocular Hypotension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Ultrasonography; Uveal Diseases | 1996 |
[Successful pressure decrease and improved patient quality of life by Trusopt].
Topics: Adult; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1996 |
Continuous intraocular pressure measurement by telemetry in alpha-chymotrypsin-induced glaucoma model in the rabbit: effects of timolol, dorzolamide, and epinephrine.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Chymotrypsin; Circadian Rhythm; Disease Models, Animal; Epinephrine; Female; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol | 1996 |
[Carbonic anhydrase inhibitors with topical action in the treatment of glaucomatous diseases. A preliminary note].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Chronic Disease; Combined Modality Therapy; Corneal Edema; Drug Evaluation; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Time Factors | 1997 |
[Effectiveness of dorzolamide as added therapy in glaucoma patients with maximum tolerated drug therapy. A pilot study].
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Sulfonamides; Thiophenes; Treatment Outcome | 1997 |
[Ocular pulse amplitude and local carbonic anhydrase inhibition].
Topics: Adult; Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pulsatile Flow; Regional Blood Flow; Sulfonamides; Thiophenes | 1997 |
Influence of dorzolamide on corneal thickness, endothelial cell count and corneal sensibility.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Cell Count; Chronic Disease; Cornea; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Sensation; Sulfonamides; Thiophenes; Timolol | 1998 |
The effect of aqueous humor suppressants on intravitreal gas bubble duration in rabbits.
Topics: Absorption; Administration, Topical; Animals; Aqueous Humor; Clonidine; Fluorocarbons; Injections; Intraocular Pressure; Rabbits; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Time Factors; Timolol; Vitreous Body | 1998 |
[Glaucoma in the elderly].
Topics: Aged; Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Trabeculectomy | 1998 |
Glaucomatocyclitic crisis in a child.
Topics: Adolescent; Clonidine; Corneal Edema; Diagnosis, Differential; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Male; Pain; Prednisolone; Sulfonamides; Syndrome; Thiophenes; Timolol; Uveitis, Intermediate; Vision Disorders; Visual Acuity | 1998 |
Update in glaucoma: the new pharmacotherapies. Dorzolamide hydrochloride.
Topics: Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1998 |
Combination of systemic acetazolamide and topical dorzolamide.
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Corneal Diseases; Drug Therapy, Combination; Endothelium, Corneal; Glaucoma; Humans; Intraocular Pressure; Sulfonamides; Thiophenes | 1998 |
Carbonic anhydrase inhibitors: inhibition of isozymes I, II and IV with N-hydroxysulfonamides--a novel class of intraocular pressure lowering agents.
Topics: Acetamides; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cattle; Glaucoma; Humans; Hydroxylamines; Intraocular Pressure; Isoenzymes; Male; Rabbits; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids; Thiophenes; Tosyl Compounds | 1998 |
Intraocular pressure in rabbits by telemetry II: effects of animal handling and drugs.
Topics: Animal Husbandry; Animals; Circadian Rhythm; Clonidine; Epinephrine; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol; Tonometry, Ocular | 1998 |
Comparison of intraocular pressure lowering by topical and systemic carbonic anhydrase inhibitors in the rabbit.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Hydrogen-Ion Concentration; Injections, Intravenous; Intraocular Pressure; Male; Methazolamide; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes; Tonometry, Ocular | 1999 |
[Four new drugs for glaucoma: apraclonidine, brimonidine, dorzolamide and latanoprost].
Topics: Adrenergic alpha-Agonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Clonidine; Drug Approval; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Netherlands; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes | 1999 |
Regulation of intraocular pressure after water drinking.
Topics: Aqueous Humor; Blood-Aqueous Barrier; Carbonic Anhydrase Inhibitors; Drinking; Follow-Up Studies; Humans; Intraocular Pressure; Ophthalmic Solutions; Osmosis; Reference Values; Sulfonamides; Thiophenes | 1999 |
Irreversible corneal decompensation in patients treated with topical dorzolamide.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Corneal Edema; Endothelium, Corneal; Female; Glaucoma; Humans; Intraocular Pressure; Keratoplasty, Penetrating; Male; Middle Aged; Ophthalmic Solutions; Refractive Errors; Retrospective Studies; Sulfonamides; Thiophenes; Visual Acuity | 1999 |
Anorexia, depression and dementia induced by dorzolamide eyedrops (Trusopt).
Topics: Aged; Anorexia; Carbonic Anhydrase Inhibitors; Dementia; Depression; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes; Visual Acuity | 1999 |
[Is corneal thickness measurement reliable and useful?].
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antihypertensive Agents; Cornea; Corneal Transplantation; Diabetes Mellitus; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Observer Variation; Ocular Hypertension; Reproducibility of Results; Sulfonamides; Thiophenes; Ultrasonography | 1999 |
Dorzolamide-timolol combination versus concomitant administration of its components.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Timolol | 1999 |
Carbonic anhydrase inhibitors. Part 71. Synthesis and ocular pharmacology of a new class of water-soluble, topically effective intraocular pressure lowering sulfonamides incorporating picolinoyl moieties.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Carbodiimides; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Humans; Intraocular Pressure; Male; Picolinic Acids; Rabbits; Solubility; Sulfonamides; Thiophenes; Water | 1999 |
The effectiveness and safety of dorzolamide 2% in addition to multiple topical antiglaucoma medications.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Sulfonamides; Thiophenes | 1999 |
A comparison of the effectiveness of dorzolamide and acetazolamide in preventing post-operative intraocular pressure rise following phacoemulsification. 1999; 43 (5): 344-6.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Carbonic Anhydrase Inhibitors; Humans; Intraocular Pressure; Phacoemulsification; Postoperative Complications; Sulfonamides; Thiophenes | 1999 |
Delayed, recurrent hypotonous maculopathy following aqueous suppressant therapy in pseudophakia.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Macula Lutea; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Prednisolone; Prodrugs; Pseudophakia; Recurrence; Retinal Diseases; Sulfonamides; Thiophenes; Ultrasonography | 1999 |
Increased optic nerve head blood flow after 1 week of twice daily topical brinzolamide treatment in Dutch-belted rabbits.
Topics: Animals; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Hemodynamics; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Ophthalmic Solutions; Optic Disk; Rabbits; Sulfonamides; Thiazines; Thiophenes | 2000 |
Comparison of the efficacy and safety of latanoprost 0.005% compared to brimonidine 0.2% or dorzolamide 2% when added to a topical beta-adrenergic blocker in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Safety; Sulfonamides; Thiophenes; Tonometry, Ocular | 2000 |
Optic nerve oxygen tension: effects of intraocular pressure and dorzolamide.
Topics: Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Infusions, Intravenous; Intraocular Pressure; Optic Nerve; Oxygen; Sulfonamides; Swine; Thiophenes | 2000 |
[Central corneal thickness in normal eyes, patients with ocular hypertension, normal-pressure and open-angle glaucomas--a clinical study].
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Case-Control Studies; Cornea; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Reference Values; Sex Distribution; Sulfonamides; Thiophenes | 2000 |
Comparison of the ocular hypotensive effect of brimonidine, dorzolamide, latanoprost, or artificial tears added to timolol in glaucomatous monkey eyes.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma; Intraocular Pressure; Latanoprost; Macaca fascicularis; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Random Allocation; Sulfonamides; Thiophenes; Timolol | 2000 |
[Effect of Trusopt on normal intraocular pressure values in children].
Topics: Adolescent; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Humans; Intraocular Pressure; Sulfonamides; Thiophenes | 2000 |
Effect of topical administration of 2% dorzlamide hydrochloride or 2% dorzlamide hydrochloride-0.5% timolol maleate on intraocular pressure in clinically normal horses.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Chemistry, Pharmaceutical; Drug Combinations; Female; Horses; Intraocular Pressure; Male; Random Allocation; Regression Analysis; Sulfonamides; Thiophenes; Timolol | 2001 |
[Analysis of glaucoma therapy costs in Poland. I--population of the Mazovian District].
Topics: Adult; Aged; Aged, 80 and over; Costs and Cost Analysis; Disease Progression; Female; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Office Visits; Pilocarpine; Poland; Sulfonamides; Thiophenes; Timolol | 2000 |
Changes in intraocular pressure associated with topical dorzolamide and oral methazolamide in glaucomatous dogs.
Topics: Administration, Oral; Administration, Topical; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Drug Administration Schedule; Female; Glaucoma; Intraocular Pressure; Male; Methazolamide; Ophthalmic Solutions; Sulfonamides; Thiophenes; Treatment Outcome | 2001 |
Effects of topical application of a 2% solution of dorzolamide on intraocular pressure and aqueous humor flow rate in clinically normal dogs.
Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Dogs; Female; Fluorophotometry; Glaucoma; Intraocular Pressure; Male; Random Allocation; Sulfonamides; Thiophenes | 2001 |
[Additive effects of topical carbonic anhydrase inhibitors].
Topics: Aged; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2001 |
[Innovative glaucoma therapy. Glaucoma therapy with topical carbonic anhydrase inhibitors].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Rabbits; Sulfonamides; Thiazines; Thiophenes; Time Factors; Timolol | 2001 |
Effect of Xalatan(R) and Cosopt(R) on the vascular tone of quiescent isolated pig ciliary arteries.
Topics: Animals; Antihypertensive Agents; Ciliary Arteries; Culture Techniques; Dose-Response Relationship, Drug; Drug Combinations; Intraocular Pressure; Latanoprost; Potassium Chloride; Prostaglandins F, Synthetic; Sulfonamides; Swine; Thiophenes; Timolol; Vasoconstriction | 2002 |
Additive intraocular pressure lowering effect of various medications with latanoprost.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Synergism; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Sulfonamides; Thiophenes | 2002 |
Inhibitors of NHE-1 Na+/H+ exchange reduce mouse intraocular pressure.
Topics: Administration, Topical; Amiloride; Animals; Antihypertensive Agents; Aqueous Humor; Bumetanide; Diuretics; Electrophysiology; Female; Intraocular Pressure; Male; Mice; Sodium-Hydrogen Exchangers; Sulfonamides; Thiophenes | 2002 |
[Weill-Marchesani syndrome. Late athalamia following antiglaucomatous surgery].
Topics: Abnormalities, Multiple; Adult; Cataract Extraction; Combined Modality Therapy; Drug Resistance; Dwarfism; Female; Fingers; Glaucoma, Angle-Closure; Hand Deformities, Congenital; Humans; Intraocular Pressure; Iridectomy; Lens Implantation, Intraocular; Lens, Crystalline; Mitomycins; Phacoemulsification; Postoperative Complications; Sulfonamides; Syndrome; Thiophenes; Trabeculectomy; Vitrectomy | 2002 |
[Influence of anticholinergic drugs on the intraocular tension of medicinally treated glaucoma simplex (author's transl)].
Topics: Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Pizotyline; Thiophenes | 1979 |
Evaluation of a topically administered carbonic anhydrase inhibitor (MK-927) in normotensive and glaucomatous beagles.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Female; Glaucoma; Intraocular Pressure; Male; Sulfonamides; Thiophenes | 1991 |
Topically active carbonic anhydrase inhibitors. 4. [(Hydroxyalkyl)sulfonyl]benzene and [(hydroxyalkyl)sulfonyl]thiophenesulfonamides.
Topics: Administration, Topical; Animals; Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Chymotrypsin; Glutathione; Intraocular Pressure; Ocular Hypertension; Rabbits; Structure-Activity Relationship; Sulfonamides; Thiophenes | 1991 |
MK-507 (L-671,152), a topically active carbonic anhydrase inhibitor, reduces aqueous humor production in monkeys.
Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Female; Fluorophotometry; Intraocular Pressure; Macaca fascicularis; Sulfonamides; Thiophenes; Tonometry, Ocular | 1991 |
L-662,583 is a topically effective ocular hypotensive carbonic anhydrase inhibitor in experimental animals.
Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ciliary Body; Eye; Female; In Vitro Techniques; Intraocular Pressure; Iris; Macaca fascicularis; Male; Rabbits; Sulfonamides; Thiophenes | 1990 |
Chemical and pharmacological properties of MK-927, a sulfonamide carbonic anhydrase inhibitor that lowers intraocular pressure by the topical route.
Topics: Administration, Topical; Animals; Anterior Eye Segment; Carbonic Anhydrase Inhibitors; Intraocular Pressure; Male; Rabbits; Sulfonamides; Thiophenes | 1990 |
The ocular hypotensive effect of the topical carbonic anhydrase inhibitor L-671,152 in glaucomatous monkeys.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Female; Glaucoma; Intraocular Pressure; Laser Therapy; Macaca fascicularis; Molecular Structure; Sulfonamides; Thiophenes | 1990 |
The effect of MK-927, a topical carbonic anhydrase inhibitor, on IOP in glaucomatous monkeys.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Intraocular Pressure; Macaca fascicularis; Sulfonamides; Thiophenes; Time Factors; Tonometry, Ocular | 1990 |
MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chymotrypsin; Ciliary Body; Dose-Response Relationship, Drug; Female; Intraocular Pressure; Iris; Kinetics; Macaca fascicularis; Male; Ocular Hypertension; Rabbits; Sulfonamides; Thiophenes | 1990 |
Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity.
Topics: Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Glaucoma; Guinea Pigs; Intraocular Pressure; Ocular Hypertension; Rabbits; Skin; Sulfonamides; Thiophenes | 1989 |
Preclinical studies on L-671,152, a topically effective ocular hypotensive carbonic anhydrase inhibitor.
Topics: Animals; Carbonic Anhydrase Inhibitors; Intraocular Pressure; Macaca fascicularis; Ophthalmic Solutions; Sulfonamides; Thiophenes | 1989 |
Ocular hypotensive activity and disposition of the topical carbonic anhydrase inhibitor 6-hydroxy-benzo[b]thiophene-2-sulfonamide, L-650,719, in the rabbit.
Topics: Animals; Carbonic Anhydrase Inhibitors; Cellulose; Chemical Phenomena; Chemistry; Ciliary Body; Cornea; Dose-Response Relationship, Drug; Intraocular Pressure; Male; Rabbits; Solubility; Thiophenes; Tissue Distribution | 1989 |
Topical carbonic anhydrase inhibitors.
Topics: Administration, Topical; Benzothiazoles; Carbonic Anhydrase Inhibitors; Ethoxzolamide; Gels; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiazoles; Thiophenes | 1989 |
Ocular effects of a N,N-disubstituted 5-OH aminotetralin (N-0437): evidence for a dual mechanism of action.
Topics: Administration, Topical; Animals; Biomechanical Phenomena; Cebus; Dose-Response Relationship, Drug; Eye; Intraocular Pressure; Naphthalenes; Pupil; Rabbits; Tetrahydronaphthalenes; Thiophenes; Time Factors | 1987 |