Compounds > thiophenes
Page last updated: 2024-08-18

thiophenes and Granulocytic Leukemia, Chronic

thiophenes has been researched along with Granulocytic Leukemia, Chronic in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's2 (20.00)29.6817
2010's4 (40.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Akahane, K; Björn, N; Inukai, T; Keszei, M; Lotfi, K; Madapura, HS; Malyukova, A; Nagy, N; Nguyen, TTT; Salamon, D; Stenke, L; Tamai, M; Ujvari, D; Wallvik, J; Yektaei-Karin, E; Zovko, A1
Chen, GQ; Fang, ZX; Gao, FH; Gao, SM; Jin, J; Jing, B; Lei, H; Liu, CX; Liu, LG; Liu, M; Lu, Y; Shan, HZ; Tong, Y; Wang, WW; Wu, YL; Wu, YZ; Xia, L; Xiao, XH; Xu, HZ; Yang, L; Zheng, JK; Zhou, L1
Cho, HC; Kuo, SC; Lee, CY; Lee, MR; Lu, CC; Tsai, FJ; Tsai, SC; Wen, YF; Yang, JS1
Jin, J; Lei, H; Li, X; Liu, M; Luo, H; Wu, Y; Xu, H; Yang, L1
Fukuda, T; Kasama, T; Miura, O; Suwa, S; Uchida, E; Watanabe, K; Yoshimoto, R1
Cao, R; Huang, N; Wang, Y1
Gong, FJ; Li, RJ; Liu, JH; Peng, HL; Zhang, GS1
Barutca, S; Bolaman, Z; Kadikoylu, G; Meydan, N; Yavasoglu, I1
Gibson, W; Jackman, AL; Kimbell, R; Kobayashi, H; Miyachi, H; Takemura, Y1
Kobayashi, H; Ohnuma, T; Takemura, Y1

Other Studies

10 other study(ies) available for thiophenes and Granulocytic Leukemia, Chronic

ArticleYear
Combination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells.
    Cell death & disease, 2021, 09-25, Volume: 12, Issue:10

    Topics: Antigens, CD34; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Survival; Clone Cells; Drug Resistance, Neoplasm; Drug Synergism; Hematopoietic Stem Cells; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphate-Binding Proteins; Poly(ADP-ribose) Polymerases; Pore Forming Cytotoxic Proteins; Protein Kinase Inhibitors; Pyrimidines; Pyroptosis; Small Molecule Libraries; Thiophenes

2021
Targeting USP47 overcomes tyrosine kinase inhibitor resistance and eradicates leukemia stem/progenitor cells in chronic myelogenous leukemia.
    Nature communications, 2021, 01-04, Volume: 12, Issue:1

    Topics: Animals; Cell Proliferation; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice, Knockout; Neoplastic Stem Cells; Proteasome Endopeptidase Complex; Protein Binding; Protein Kinase Inhibitors; Protein Stability; Proteolysis; ras Proteins; RNA, Messenger; Signal Transduction; STAT5 Transcription Factor; Thiophenes; Ubiquitin Thiolesterase; Ubiquitin-Specific Proteases; Xenograft Model Antitumor Assays; Y-Box-Binding Protein 1

2021
ITR‑284 modulates cell differentiation in human chronic myelogenous leukemia K562 cells.
    Oncology reports, 2018, Volume: 39, Issue:1

    Topics: Antineoplastic Agents; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Forkhead Box Protein M1; Fusion Proteins, bcr-abl; GATA1 Transcription Factor; GATA2 Transcription Factor; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; NF-E2 Transcription Factor, p45 Subunit; Proto-Oncogene Proteins c-myc; Thiophenes; Tretinoin; Zinc Finger Protein GLI1

2018
Chk1 inhibitors overcome imatinib resistance in chronic myeloid leukemia cells.
    Leukemia research, 2018, Volume: 64

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Pyrazoles; Pyrimidines; Thiophenes; Urea; Xenograft Model Antitumor Assays

2018
TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation.
    International journal of oncology, 2019, Volume: 54, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Blast Crisis; Cell Line, Tumor; Cell Proliferation; Female; Fusion Proteins, bcr-abl; Gene Expression Regulation, Neoplastic; HLA-A24 Antigen; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Protein Phosphatase 2; Quinolones; Thiophenes; Young Adult

2019
Discovery of 2-Acylaminothiophene-3-Carboxamides as Multitarget Inhibitors for BCR-ABL Kinase and Microtubules.
    Journal of chemical information and modeling, 2015, Nov-23, Volume: 55, Issue:11

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Microtubules; Molecular Docking Simulation; Point Mutation; Protein Kinase Inhibitors; Thiophenes

2015
Dup-697, a specific COX-2 inhibitor, suppresses growth and induces apoptosis on K562 leukemia cells by cell-cycle arrest and caspase-8 activation.
    Annals of hematology, 2008, Volume: 87, Issue:2

    Topics: Apoptosis; Bone Marrow Cells; Caspase 8; Cell Cycle; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Enzyme Activation; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Thiophenes

2008
Chronic myeloid leukemia following the treatment of rectal adenocarcinoma.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Fluorouracil; Fusion Proteins, bcr-abl; Humans; In Situ Hybridization, Fluorescence; Irinotecan; Leucovorin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Neoplasms; Male; Neoplasms, Second Primary; Organoplatinum Compounds; Oxaliplatin; Philadelphia Chromosome; Quinazolines; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Thiophenes

2008
Cellular pharmacokinetics of ZD1694 in cultured human leukaemia cells sensitive, or made resistant, to this drug.
    Journal of cancer research and clinical oncology, 1996, Volume: 122, Issue:2

    Topics: Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Folic Acid; Humans; Intracellular Fluid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Polyglutamic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Tetrahydrofolate Dehydrogenase; Thiophenes; Thymidylate Synthase; Tritium; Tumor Cells, Cultured

1996
Variable expression of RFC1 in human leukemia cell lines resistant to antifolates.
    Cancer letters, 1998, Feb-27, Volume: 124, Issue:2

    Topics: Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Antagonists; Humans; Leucovorin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Tetrahydrofolate Dehydrogenase; Thiophenes; Tumor Cells, Cultured

1998