Page last updated: 2024-08-18

thiophenes and Gastric Ulcer

thiophenes has been researched along with Gastric Ulcer in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19908 (38.10)18.7374
1990's6 (28.57)18.2507
2000's4 (19.05)29.6817
2010's3 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
El-Hawash, SA; El-Messmary, H; El-Miligy, MM; Hazzaa, AA; Nassra, RA1
Abd El Razik, HA; AboulWafa, OM; Bayad, AE; El-Ashmawy, IM; El-Shoukrofy, MS1
Baudler, M; Brehm, C; Dullweber, F; Figala, V; Herrmann, M; Klein, T; Prinz, W1
Fan, DS; Guo, L; Ji, CX; Li, W; Liang, ZL; Xu, RM; Zhang, JJ1
Alagarsamy, V; Raja Solomon, V; Vijayakumar, S1
Alagarsamy, V; Anjana, GV; Deepa, G; Parthiban, P; Solomon, VR1
Abd el-Salam, OM; el-Batran, S; el-Shenawy, SM; Fakhr, IM; Radwan, MA1
Kholoussy, AM; Kumashiro, R; Matsumoto, T; Pavlides, CA1
Derégnaucort, J; Hardy-Houis, M1
Emmenegger, U; Flogerzi, B; Halter, F; Ott, K; Schuerer-Maly, CC1
Caccamo, F; Caruso, A; Cutuli, VM; Santagati, NA1
Furr, MO; Goodrich, LR; Robertson, JL; Warnick, LD1
Alise, G; Apolito, A; Lampa, E; Pedone, P; Russo, G1
Caruso Aa, L; Cutuli, V; Guerrera, F; Salerno, L; Sarvà, MC; Siracusa, MA1
Abdallah, SS; Bravo, L; Darias, V; Expósito-Orta, MA; Lissavetsky, J; Manzanares, J; Sánchez Mateo, CC1
Caruso, A; Felice, A; Guerrera, F; Leone, MG; Ronsisvalle, G; Salerno, L; Siracusa, MA1
Allison, DL; Anderson, RL; Bach, T; Bailey, PJ; Dallob, AL; Durette, PL; Hand, KM; Hopple, SL; Luell, S; Meurer, R1
Amico-Roxas, M; Caruso, A; Russo, F; Santagati, A; Santagati, M; Trombadore, S1
Aloup, JC; Bouchaudon, J; Deregnaucourt, J; Farge, D; Hardy-Houis, M; James, C1
Hashimoto, N; Kholoussy, AM; Kumashiro, R; Matsumoto, T; Piotrowski, JJ1
Harigaya, S; Kiyomoto, A; Murata, S; Tamaki, H; Tanaka, M1

Other Studies

21 other study(ies) available for thiophenes and Gastric Ulcer

ArticleYear
New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study.
    Future medicinal chemistry, 2017, Volume: 9, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Formaldehyde; Humans; Lipoxygenase Inhibitors; Molecular Docking Simulation; Rats; Stomach Ulcer; Structure-Activity Relationship; Thiophenes

2017
Pyrazoles containing thiophene, thienopyrimidine and thienotriazolopyrimidine as COX-2 selective inhibitors: Design, synthesis, in vivo anti-inflammatory activity, docking and in silico chemo-informatic studies.
    Bioorganic chemistry, 2019, Volume: 85

    Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Design; Male; Mice; Molecular Docking Simulation; Molecular Structure; Pyrazoles; Pyrimidines; Rats; Stomach Ulcer; Structure-Activity Relationship; Thiophenes

2019
Characterization of eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivo.
    Biochemical pharmacology, 2008, Sep-15, Volume: 76, Issue:6

    Topics: Acetic Acid; Aniline Compounds; Animals; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Edema; Female; Humans; Male; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiophenes

2008
Evaluation of the anti-ulcerogenic activity of the antidepressants duloxetine, amitriptyline, fluoxetine and mirtazapine in different models of experimental gastric ulcer in rats.
    European journal of pharmacology, 2012, Sep-15, Volume: 691, Issue:1-3

    Topics: Amitriptyline; Animals; Anti-Ulcer Agents; Antidepressive Agents; Disease Models, Animal; Duloxetine Hydrochloride; Fluoxetine; Immersion; Indomethacin; Male; Mianserin; Mirtazapine; Rats; Rats, Sprague-Dawley; Reserpine; Restraint, Physical; Stomach Ulcer; Stress, Psychological; Thiophenes; Water

2012
Synthesis of 2-mercapto-3-substituted-5,6-dimethylthieno[2,3-d] pyrimidin-4(3H)-ones as new analgesic, anti-inflammatory agents.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2007, Volume: 61, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Pain Measurement; Pyrimidinones; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Sulfhydryl Compounds; Thiophenes

2007
Synthesis and pharmacological investigation of 3-subsituted-amino-2-methylsulfanyl-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-ones as analgesic and anti-inflammatory agents.
    Archiv der Pharmazie, 2007, Volume: 340, Issue:7

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Female; Magnetic Resonance Spectroscopy; Male; Pain Measurement; Pyrimidinones; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Sulfones; Thiophenes

2007
Synthesis and pharmacological evaluation of 2-substituted benzo[b]thiophenes as anti-inflammatory and analgesic agents.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Acetic Acid; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Carrageenan; Edema; Liver; Mice; Pain; Pain Threshold; Piroxicam; Rats; Stomach Ulcer; Structure-Activity Relationship; Thiophenes

2009
Thrombotic etiology of stress ulcers. 1. The effect of anticoagulant and antiplatelet aggregators in the development of stress ulcers in rats.
    The American surgeon, 1983, Volume: 49, Issue:8

    Topics: Animals; Anticoagulants; Aspirin; Dipyridamole; Gastric Acidity Determination; Gastric Mucosa; Heparin; Male; Peptic Ulcer Hemorrhage; Platelet Aggregation; Platelet Count; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological; Thiophenes; Thrombosis; Ticlopidine

1983
[Antisecretory and antiulcer activities of N-methyl-2-(2-pyridyl)-2,3,4,5,-tetrahydro-2-thiophene-carbothioamide (R.P. .40, 749) (author's transl)].
    Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie, 1982, Mar-22, Volume: 294, Issue:12

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Female; Gastric Juice; Rats; Stomach Ulcer; Thiophenes

1982
Interleukin-1 and experimental gastric ulcer healing in the rat.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1993, Volume: 44, Issue:1

    Topics: Animals; Female; Gastric Acid; Interleukin-1; Rats; Rats, Wistar; Stomach Ulcer; Thiophenes; Weight Gain

1993
Synthesis and pharmacological evaluation of thieno[2,3-d]pyrimidin-2,4-dione and 5H-pyrimido [5,4-b]indol-2,4-dione derivatives.
    Farmaco (Societa chimica italiana : 1989), 1995, Volume: 50, Issue:10

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Behavior, Animal; Carrageenan; Deuterium; Fungi; Indoles; Inflammation; Magnetic Resonance Spectroscopy; Male; Mice; Microbial Sensitivity Tests; Pain Measurement; Peritonitis; Pyrimidinones; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiophenes

1995
A toxicity study of eltenac, a nonsteroidal anti-inflammatory drug, in horses.
    Journal of veterinary pharmacology and therapeutics, 1998, Volume: 21, Issue:1

    Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Appetite; Dose-Response Relationship, Drug; Double-Blind Method; Female; Horses; Injections, Intravenous; Leukocyte Count; Male; Mouth; Orchiectomy; Stomach; Stomach Ulcer; Thiophenes

1998
[Specific and aspecific activity of an antihistaminic of the H1 type: HC 20-511 or ketothiphen (benzo-cyclohepta-thiophenone derivative)].
    Bollettino chimico farmaceutico, 1977, Volume: 116, Issue:11

    Topics: Albuterol; Anaphylaxis; Animals; Anura; Bronchial Spasm; Cardiovascular System; Chlorpheniramine; Dogs; Drug Evaluation, Preclinical; Female; Gastric Juice; Guinea Pigs; Histamine H1 Antagonists; Inflammation; Male; Mice; Muscle, Smooth; Piperidines; Pizotyline; Rats; Respiration; Stomach Ulcer; Thiophenes

1977
Synthesis and pharmacological properties of 2-nitro-3-substituted-amino benzo(b)thiophenes and their 5-chloro derivatives.
    Farmaco (Societa chimica italiana : 1989), 1992, Volume: 47, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Exudates and Transudates; Male; Mice; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiophenes

1992
Synthesis and preliminary pharmacological study of thiophene analogues of the antipyretic and analgesic agent ethenzamide.
    Archiv der Pharmazie, 1992, Volume: 325, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Hypnotics and Sedatives; Male; Mice; Rats; Rats, Inbred Strains; Salicylamides; Stomach Ulcer; Thiophenes

1992
Synthesis and pharmacological properties of 2-nitro-3-substituted-amino benzo[b]thiophenes and 1-substituted benzothieno[2,3-d]imidazoles.
    Farmaco (Societa chimica italiana : 1989), 1990, Volume: 45, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Exudates and Transudates; Imidazoles; Male; Mice; Nitro Compounds; Rats; Rats, Inbred Strains; Stomach Ulcer; Thiophenes

1990
Pharmacology of the dual inhibitor of cyclooxygenase and 5-lipoxygenase 3-hydroxy-5-trifluoromethyl-N-(2-(2-thienyl)-2-phenyl-ethenyl)-benzo (b)thiophene-2-carboxamide.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Cyclooxygenase Inhibitors; Dogs; Female; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains; Stomach Ulcer; Thiophenes

1988
Synthesis and pharmacological properties of benzothienothiadiazolopyrimidine derivatives. III.
    Il Farmaco; edizione scientifica, 1987, Volume: 42, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Anticonvulsants; Behavior, Animal; Chemical Phenomena; Chemistry; Mice; Parasympatholytics; Pyrimidines; Rats; Stomach Ulcer; Thiophenes

1987
Synthesis and antisecretory and antiulcer activities of derivatives and analogues of 2-(2-pyridyl)tetrahydrothiophene-2-carbothioamide.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Female; Gastric Juice; Histamine; Indicators and Reagents; Male; Pyridines; Rats; Rats, Inbred Strains; Stomach Ulcer; Structure-Activity Relationship; Thiophenes

1987
Antiplatelet aggregators inhibit development of stress ulcers in Sprague-Dawley rats.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1985, Volume: 17, Issue:1

    Topics: Animals; Anticoagulants; Aspirin; Capillaries; Dipyridamole; Gastric Mucosa; Male; Platelet Aggregation; Pyridines; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological; Sulfinpyrazone; Thiophenes; Thrombosis; Ticlopidine

1985
Pharmacological properties of a new anticholinergic agent, 1, 1-dimethyl-5-methoxy-3-(dithien-2-ylmethylene) piperidinium bromide (SA-504).
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:5

    Topics: Anesthetics, Local; Animals; Cardiovascular System; Cats; Depression, Chemical; Female; Ganglia, Autonomic; Gastric Juice; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Irritants; Male; Methemoglobin; Methyl Ethers; Mice; Muscle Contraction; Muscle, Smooth; Mydriatics; Parasympatholytics; Piperidines; Rats; Respiration; Salivation; Stomach Ulcer; Thiophenes

1972