thiophenes has been researched along with Experimental Hepatoma in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 12 (63.16) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bu, Q; Lin, HJ; Mao, YQ; Peng, F; Xu, YZ; Yang, L; Yang, SY; Yu, LT; Zhao, YL; Zheng, RL; Zhou, Y | 1 |
| Cai, YJ; Chen, Y; Ding, J; Geng, MY; Huang, M; Luo, HB; Miao, ZH; Qian, XH; Qin, YX; Shen, X; Xu, YF; Yang, F; Zhu, H | 1 |
| Ishihara, M; Kinjo, M; Kohga, S; Ogawa, H; Tanaka, K; Tanaka, N | 1 |
| Egner, PA; Kelloff, GJ; Kensler, TW; Primiano, T; Roebuck, BD; Sutter, TR | 1 |
| Groopman, JD; Kensler, TW; Roebuck, BD | 2 |
| Kensler, TW; MacMillan, DL; Maxuitenko, YY; Roebuck, BD | 1 |
| Bolton, MG; Groopman, JD; Jacobson, LP; Kensler, TW; Maxuitenko, YY; Muñoz, A; Roebuck, BD | 1 |
| Groopman, JD; Kensler, TW; Musser, SM; Scholl, P | 1 |
| Dolan, PM; Egner, PA; Gange, SJ; Groopman, JD; Kensler, TW; Muñoz, A; Roebuck, BD; Rogers, AE | 1 |
| Curphey, TJ; Joyner, HH; Kensler, TW; Libby, AH; MacMillan, DL; Maxuitenko, YY; Roebuck, BD | 1 |
| Bu, W; Li, XM; Qin, LX; Tang, ZY; Xia, JL | 1 |
| Antoniu, BA; Compton, CC; Fernández-Del Castillo, C; Hartwig, W; Jimenez, RE; Warshaw, AL | 1 |
| Arlt, M; Gänsbacher, B; Harbeck, N; Kopitz, C; Krüger, A; Magdolen, V; Schmitt, M; Soeltl, R; Sopov, I | 1 |
| Curphey, TJ; Eaton, DL; Groopman, JD; Kensler, TW; Roebuck, BD | 1 |
| Groopman, JD; Kensler, TW; Liu, YL; Roebuck, BD; Rogers, AE | 1 |
| DeMatos, P; Egner, PA; Groopman, JD; Kensler, TW; Love-Hunt, A | 1 |
| Dolan, PM; Egner, PA; Groopman, JD; Kensler, TW; Roebuck, BD | 1 |
| Bueding, E; De Long, MJ; Dolan, P; Santamaria, AB | 1 |
2 review(s) available for thiophenes and Experimental Hepatoma
| Article | Year |
|---|---|
Carcinogen-DNA and protein adducts as intermediate biomarkers for human chemoprotection trials.
Topics: Aflatoxins; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; DNA; Humans; Liver Neoplasms, Experimental; Neoplasms; Proteins; Pyrazines; Thiones; Thiophenes | 1994 |
Molecular dosimetry of aflatoxin DNA adducts in humans and experimental rat models.
Topics: Aflatoxins; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; China; DNA; Environmental Exposure; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Rats; Thiones; Thiophenes | 1992 |
17 other study(ies) available for thiophenes and Experimental Hepatoma
| Article | Year |
|---|---|
Small molecular anticancer agent SKLB703 induces apoptosis in human hepatocellular carcinoma cells via the mitochondrial apoptotic pathway invitro and inhibits tumor growth invivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Caspases; Dose-Response Relationship, Drug; Enzyme Activation; Female; Hep G2 Cells; Humans; K562 Cells; Liver Neoplasms, Experimental; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Thiophenes; Tumor Burden; Xenograft Model Antitumor Assays | 2011 |
R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II.
Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Division; Cell Proliferation; Cytochromes c; DNA Topoisomerases, Type II; Enzyme Inhibitors; Female; Flow Cytometry; G2 Phase; Humans; Imides; In Situ Nick-End Labeling; Isoquinolines; Liver Neoplasms, Experimental; Mice; Mice, Inbred Strains; Naphthalimides; Organophosphonates; Poly(ADP-ribose) Polymerases; Sarcoma, Experimental; Thiophenes; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 2007 |
Effects of 5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride (Ticlopidine), a platelet aggregation inhibitor, on blood-borne metastasis.
Topics: Animals; Cell Line; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplastic Cells, Circulating; Platelet Aggregation; Pyridines; Rats; Thiophenes; Ticlopidine | 1981 |
Intermittent dosing with oltipraz: relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Enzyme Induction; Glutathione Transferase; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1995 |
Evaluation of the post-initiation effects of oltipraz on aflatoxin B1-induced preneoplastic foci in a rat model of hepatic tumorigenesis.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Body Weight; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes; Time Factors | 1993 |
Transient intervention with oltipraz protects against aflatoxin-induced hepatic tumorigenesis.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; DNA; DNA Adducts; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1993 |
Inhibition of aflatoxin Ml excretion in rat urine during dietary intervention with oltipraz.
Topics: Aflatoxin B1; Aflatoxin M1; Animals; Anticarcinogenic Agents; Cytochrome P-450 Enzyme System; Diet; Dose-Response Relationship, Drug; Inactivation, Metabolic; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1996 |
Predictive value of molecular dosimetry: individual versus group effects of oltipraz on aflatoxin-albumin adducts and risk of liver cancer.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Cell Transformation, Neoplastic; DNA Adducts; Dose-Response Relationship, Drug; Drug Administration Schedule; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1997 |
Identification of dithiolethiones with better chemopreventive properties than oltipraz.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Enzyme Induction; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1998 |
Effect of antiangiogenic agents on experimental animal models of hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents; Cell Division; Cyclohexanes; Liver Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Phenylalanine; Sesquiterpenes; Suramin; Thiophenes; Triazoles | 1999 |
Effect of matrix metalloproteinase inhibition on pancreatic cancer invasion and metastasis: an additive strategy for cancer control.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Humans; Liver Neoplasms, Experimental; Metalloendopeptidases; Mice; Mice, Nude; Neoplasm Invasiveness; Pancreatic Neoplasms; Phenylalanine; Thiophenes; Tumor Cells, Cultured | 2000 |
Hydroxamate-type matrix metalloproteinase inhibitor batimastat promotes liver metastasis.
Topics: Angiogenesis Inducing Agents; Animals; Antineoplastic Agents; Caspase 1; Female; Humans; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphoma, T-Cell; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred DBA; Mice, Nude; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Phenylalanine; Protease Inhibitors; RNA, Messenger; Thiophenes; Up-Regulation | 2001 |
Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione.
Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Enzyme Induction; gamma-Glutamyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1992 |
Protection against aflatoxin B1-induced hepatocarcinogenesis in F344 rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): predictive role for short-term molecular dosimetry.
Topics: Adenoma; Aflatoxin B1; Animals; DNA; gamma-Glutamyltransferase; Growth; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Survival Analysis; Thiones; Thiophenes | 1991 |
Molecular dosimetry of urinary aflatoxin-N7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats.
Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Biomarkers; DNA; Guanine; Liver Neoplasms, Experimental; Male; Protein Binding; Pyrazines; Rats; Rats, Inbred F344; Serum Albumin; Thiones; Thiophenes | 1992 |
Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antineoplastic Agents; Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; gamma-Glutamyltransferase; Glutathione Transferase; Heterocyclic Compounds; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Structure-Activity Relationship; Thiones; Thiophenes | 1987 |
1,2-Dithiol-3-thione analogs: effects on NAD(P)H:quinone reductase and glutathione levels in murine hepatoma cells.
Topics: Animals; Antineoplastic Agents; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Glutathione; Liver Neoplasms, Experimental; Mice; Mutation; Quinone Reductases; Structure-Activity Relationship; Thiones; Thiophenes | 1986 |