Page last updated: 2024-08-18

thiophenes and ER-Negative PR-Negative HER2-Negative Breast Cancer

thiophenes has been researched along with ER-Negative PR-Negative HER2-Negative Breast Cancer in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (53.85)24.3611
2020's6 (46.15)2.80

Authors

AuthorsStudies
Huang, SH; Liu, F; Meng, LQ; Tang, YX; Wang, SP; Wu, SQ; Xu, YG; Zhu, QH1
Badisa, RB; Mack, N; Mazzio, E; Soliman, KFA1
Gan, W; Guo, Q; Han, J; He, J; Jiang, Z; Li, Y; Liu, M; Liu, Y; Luo, L; Sun, C; Sun, X; Tang, S; Wu, Y; Xu, S; Yang, F; Yang, Y; Zhang, X; Zhu, W; Zuo, D1
Armeson, K; Britten, C; Erlander, M; Ethier, S; Giordano, A; Kappler, C; Liu, Y; Park, Y; Reuben, J; Ridinger, M; Yeh, E1
Bissanum, R; Kanokwiroon, K; Khongkow, M; Khongkow, P; Khunpitak, T; Ulhaka, K1
Amirhossein Tabatabaei Dakhili, S; Bergman, C; Dufour, J; Juengling, FD; Pérez, DJ; Velázquez-Martínez, CA; Wuest, F; Wuest, M1
Bachelet, CM; Corcé, V; Forté, J; Gontard, G; Rada, JP; Rey, NA; Salmain, M1
Chanrion, M; Dewson, G; Geneste, O; Giner, G; Gong, JN; Gräsel, J; Herold, MJ; Huang, DCS; Lalaoui, N; Lessene, G; Li, X; Lindeman, GJ; Liu, K; Maragno, AL; Merino, D; Pal, B; Schneider, E; Segal, D; Serrano, A; Smyth, GK; Vaillant, F; Visvader, JE; Whittle, JR1
Han, HH; He, XP; James, TD; Li, J; Wang, CZ; Zang, Y1
Atwell, S; Brooks, HB; Dally, RD; Durham, TB; Fales, KR; Frimpong, K; Geeganage, S; Hui, YH; Konicek, SA; Lee, MR; Margolis, BJ; Mc Cowan, JR; Meier, TI; Njoroge, FG; Roth, KD; Shepherd, TA; Si, C; Thibodeaux, S; Thrasher, KJ; Torrado, A; Toth, JL; Wang, J; Wang, Y; Wu, Z1
Bryant, C; Massey, AJ; Rawlinson, R1
Burris, TP; Kojetin, D; Wang, Y1
Green, JE; He, S; Min, DJ1

Other Studies

13 other study(ies) available for thiophenes and ER-Negative PR-Negative HER2-Negative Breast Cancer

ArticleYear
FDI-6 inhibits the expression and function of FOXM1 to sensitize BRCA-proficient triple-negative breast cancer cells to Olaparib by regulating cell cycle progression and DNA damage repair.
    Cell death & disease, 2021, 12-08, Volume: 12, Issue:12

    Topics: Cell Cycle; Cell Division; Cell Line, Tumor; DNA Damage; Forkhead Box Protein M1; Humans; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Pyridines; Thiophenes; Triple Negative Breast Neoplasms

2021
Triple Isozyme Lactic Acid Dehydrogenase Inhibition in Fully Viable MDA-MB-231 Cells Induces Cytostatic Effects That Are Not Reversed by Exogenous Lactic Acid.
    Biomolecules, 2021, 11-24, Volume: 11, Issue:12

    Topics: Cell Cycle; Cell Line, Tumor; Cell Survival; Cytostatic Agents; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glycolysis; High-Throughput Screening Assays; Humans; Lactic Acid; Pyridones; Thiophenes; Triple Negative Breast Neoplasms; Tumor Microenvironment

2021
XS-2, a novel potent dual PI3K/mTOR inhibitor, exhibits high in vitro and in vivo anti-breast cancer activity and low toxicity with the potential to inhibit the invasion and migration of triple-negative breast cancer.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 155

    Topics: Animals; Antineoplastic Agents; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epidermal Growth Factor; Humans; Mice; Mice, Nude; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Thiophenes; TOR Serine-Threonine Kinases; Triazines; Triple Negative Breast Neoplasms; Vimentin; Xenograft Model Antitumor Assays

2022
Polo-like kinase 1 (Plk1) inhibition synergizes with taxanes in triple negative breast cancer.
    PloS one, 2019, Volume: 14, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cell Cycle Proteins; Cell Line, Tumor; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Mice; Piperazines; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pyrazoles; Quinazolines; Thiophenes; Triple Negative Breast Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2019
The Anticancer Effects of FDI-6, a FOXM1 Inhibitor, on Triple Negative Breast Cancer.
    International journal of molecular sciences, 2021, Jun-22, Volume: 22, Issue:13

    Topics: Antineoplastic Agents; Caspase 3; Cell Line, Tumor; Cell Movement; Female; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; Humans; Proto-Oncogene Proteins c-bcl-2; Pyridines; Thiophenes; Triple Negative Breast Neoplasms

2021
FOXM1 Inhibitors as Potential Diagnostic Agents: First Generation of a PET Probe Targeting FOXM1 To Detect Triple-Negative Breast Cancer in vitro and in vivo.
    ChemMedChem, 2021, 12-14, Volume: 16, Issue:24

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Forkhead Box Protein M1; Humans; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Positron-Emission Tomography; Pyridines; Structure-Activity Relationship; Thiophenes; Triple Negative Breast Neoplasms

2021
Novel luminescent benzopyranothiophene- and BODIPY-derived aroylhydrazonic ligands and their dicopper(II) complexes: syntheses, antiproliferative activity and cellular uptake studies.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2021, Volume: 26, Issue:6

    Topics: Antineoplastic Agents; Boron Compounds; Cell Line, Tumor; Copper; Female; Humans; Microscopy, Fluorescence; Molecular Structure; Thiophenes; Triple Negative Breast Neoplasms

2021
Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer.
    Science translational medicine, 2017, Aug-02, Volume: 9, Issue:401

    Topics: Animals; bcl-2 Homologous Antagonist-Killer Protein; bcl-X Protein; Breast Neoplasms; Cell Line, Tumor; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Amplification; Humans; Lapatinib; Myeloid Cell Leukemia Sequence 1 Protein; Pyrimidines; Quinazolines; Receptor, ErbB-2; Survival Analysis; Taxoids; Thiophenes; Trastuzumab; Treatment Outcome; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2017
Supramolecular core-glycoshell polythiophene nanodots for targeted imaging and photodynamic therapy.
    Chemical communications (Cambridge, England), 2017, Aug-29, Volume: 53, Issue:70

    Topics: Cell Line, Tumor; Fluorescent Dyes; HeLa Cells; Hep G2 Cells; Humans; Liver Neoplasms; Macromolecular Substances; Molecular Structure; Nanoparticles; Optical Imaging; Particle Size; Photochemotherapy; Polymers; Thiophenes; Triple Negative Breast Neoplasms

2017
Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhi
    Journal of medicinal chemistry, 2017, 12-14, Volume: 60, Issue:23

    Topics: Animals; Antineoplastic Agents; Breast; Cell Line, Tumor; Cell Proliferation; Drug Discovery; Female; Folic Acid Antagonists; Humans; Male; Mice; Mice, Nude; Models, Molecular; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Sulfonamides; Thiophenes; Triple Negative Breast Neoplasms

2017
Chk1 inhibition as a novel therapeutic strategy for treating triple-negative breast and ovarian cancers.
    BMC cancer, 2014, Aug-07, Volume: 14

    Topics: Benzodiazepinones; Biomarkers, Tumor; Cell Line, Tumor; Checkpoint Kinase 1; Cisplatin; Deoxycytidine; Drug Synergism; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Indoles; MCF-7 Cells; Ovarian Neoplasms; Protein Kinase Inhibitors; Protein Kinases; Pyrazoles; Pyridones; Thiophenes; Triple Negative Breast Neoplasms; Urea

2014
Anti-proliferative actions of a synthetic REV-ERBα/β agonist in breast cancer cells.
    Biochemical pharmacology, 2015, Aug-15, Volume: 96, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin A; Female; Humans; Nuclear Receptor Subfamily 1, Group D, Member 1; Pyrrolidines; Receptor, ErbB-2; Receptors, Estrogen; Thiophenes; Triple Negative Breast Neoplasms

2015
Birinapant (TL32711) Improves Responses to GEM/AZD7762 Combination Therapy in Triple-negative Breast Cancer Cell Lines.
    Anticancer research, 2016, Volume: 36, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Checkpoint Kinase 1; Deoxycytidine; Dipeptides; DNA Repair; Female; Gemcitabine; Humans; Indoles; Phosphorylation; Thiophenes; Triple Negative Breast Neoplasms; Urea

2016