Page last updated: 2024-08-18

thiophenes and Diarrhea

thiophenes has been researched along with Diarrhea in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199010 (27.78)18.7374
1990's0 (0.00)18.2507
2000's16 (44.44)29.6817
2010's9 (25.00)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Bender, S; Boix, O; Cassier, PA; Cathomas, R; Cho, BC; Ellinghaus, P; Gajate, P; Grevel, J; Joerger, M; Navarro, A; Nogai, H; Nogova, L; Ocker, M; Park, SH; Penel, N; Rajagopalan, P; Richly, H; Sayehli, CM; Schostak, M; Schuler, M; Soo, RA; Tai, D1
Fujitsuka, N; Harada, Y; Iizuka, S; Kubota, K; Sadatomi, D; Sekine, H1
Batur, S; Dobrucali, A; Sadri, S; Sisman, G1
Barni, S; Borgonovo, K; Coinu, A; Ghidini, A; Petrelli, F1
Brown, SL; Cassim, B; Davey, MR; de Lange, W; de Villiers, TJ; Ellis, GC; Hough, FS; Lipschitz, S; Lukhele, M; Pettifor, JM1
Chakrabarti, MK; Chakrabarti, P; Chakravarty, D; Chatterjee, T; Hoque, KM; Saha, T; Sarkar, P; Sheikh, IA1
Capriati, A; Maggi, CA; Scartoni, S; Schumacher, K; Tack, J; Tonini, G1
Keating, GM; Weber, J1
Atkinson, JH; Backonja, M; Chappell, AS; Desaiah, D; Detke, MJ; Iyengar, S; Liu-Seifert, H; Skljarevski, V; Zhang, Q1
Aloi, L; Avallone, A; Budillon, A; Comella, P; Delrio, P; Iaffaioli, VR; Iodice, G; Lastoria, S; Marone, P; Pecori, B; Petrillo, A; Sandomenico, C; Scala, D; Scott, N; Tatangelo, F1
Bowyer, BA; Gwillim, EC1
Adams, AL; Brady, D; Engstrom, PF; Gallo, JM; Kilpatrick, D; Lewis, NL; Litwin, S; Meropol, NJ; Scher, R; Szarka, CE; Weiner, LM1
Botwood, N; James, RD; Price, P; Vernon, CC1
Aebi, S; Borner, MM; Büchler, MW; Friess, H; Kralidis, E1
GILBERT, SS1
SENECA, H1
KINNEAR, DG1
CIOCHETTI, D; FARIA, MC; GOLDMAN, HL; MERCURIO, MH; MURAHOVSCHI, J; RACOWSKI, P; STEIN, ML1
Allegrini, G; Barbara, C; Cupini, S; Danesi, R; Del Tacca, M; Di Paolo, A; Falcone, A; Masi, G1
Delmas, PD1
Arends, JJ; de Jong, RS; Leys, MB; Nortier, JW; Sleeboom, HP; Smit, JM; Ten Bokkel Huinink, D; Tesselaar, ME1
Aparicio, J; Balcells, M; Bosch, C; Busquier, I; Campos, JM; Galán, A; Garcerá, S; Llorca, C; López-Tendero, P; Maestu, I; Vicent, JM1
Baygani, SK; Hurley, DJ; Turner, CL; Viktrup, L; Yalcin, I1
Bisonni, R; Leon, A; Lippe, P; Lombardo, M; Marcucci, F; Massacesi, C; Mattioli, R; Pilone, A; Rocchi, MB; Terrazzino, S1
Adachi, JD; Cranney, A; O'Donnell, S; Reginster, JY; Wells, GA1
Bruyere, O; Malaise, O; Neuprez, A; Reginster, JY1
Armstrong, I; Biel, MA; Chambers, MS; Chen, Y; Garden, AS; Haddad, R; Hodge, KM; Holland, JM; Jones, CU; Ship, JA; Vitti, R; Weber, RS1
Cacciatore, L; De Marco, F; Giardina, MG; Matarazzo, M1
Goyan, JE1
Bush, H; Flamenbaum, W; Gross, ML; Hamburger, RJ; Weinger, R1
Aherne, GW; Benstead, J; Clarke, SJ; Farrugia, DC; Jackman, AL; Pritchard, DM1
Algazy, K; Giantonio, B; Haller, DG; Hardy, C; Kluijtmans, LA; O'Dwyer, PJ; Redlinger, M; Stevenson, JP; Sun, W; Whitehead, AS1
Clarke, S; Cunningham, D; Facchini, T; González Barón, M; James, R; Maroun, J; Maughan, TS; Schulz, J; Vincent, M; Zalcberg, J1
da Silva, AR1
Huggins, D; Melo, DM1
Chapman, NB; Clarke, K; Iddon, B1

Reviews

5 review(s) available for thiophenes and Diarrhea

ArticleYear
A systematic review of raltitrexed-based first-line chemotherapy in advanced colorectal cancer.
    Anti-cancer drugs, 2014, Volume: 25, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cardiotoxicity; Colorectal Neoplasms; Diarrhea; Humans; Irinotecan; Liver; Neoplasm Metastasis; Neutropenia; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Thiophenes

2014
Clinical effects of strontium ranelate in women with postmenopausal osteoporosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2005, Volume: 16 Suppl 1

    Topics: Aged; Clinical Trials, Phase III as Topic; Diarrhea; Female; Fractures, Bone; Gastritis; Humans; Middle Aged; Organometallic Compounds; Osteoporosis, Postmenopausal; Quality of Life; Risk; Spinal Fractures; Thiophenes; Uncoupling Agents

2005
Strontium ranelate for preventing and treating postmenopausal osteoporosis.
    The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3

    Topics: Bone Density; Bone Density Conservation Agents; Diarrhea; Female; Fractures, Bone; Humans; Organometallic Compounds; Osteoporosis, Postmenopausal; Randomized Controlled Trials as Topic; Thiophenes

2006
Strontium ranelate in the prevention of osteoporotic fractures.
    International journal of clinical practice, 2007, Volume: 61, Issue:2

    Topics: Aged; Aged, 80 and over; Bone Density; Bone Density Conservation Agents; Diarrhea; Female; Humans; Middle Aged; Nausea; Organometallic Compounds; Osteoporosis, Postmenopausal; Thiophenes; Treatment Outcome

2007
Efficacy, tolerability and management of raltitrexed (Tomudex) monotherapy in patients with advanced colorectal cancer. a review of phase II/III trials.
    European journal of cancer (Oxford, England : 1990), 2002, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antimetabolites, Antineoplastic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Diarrhea; Female; Humans; Leukopenia; Male; Middle Aged; Nausea; Neutropenia; Pain; Quinazolines; Randomized Controlled Trials as Topic; Survival Analysis; Thiophenes; Vomiting

2002

Trials

12 trial(s) available for thiophenes and Diarrhea

ArticleYear
Rogaratinib in patients with advanced cancers selected by FGFR mRNA expression: a phase 1 dose-escalation and dose-expansion study.
    The Lancet. Oncology, 2019, Volume: 20, Issue:10

    Topics: Acute Kidney Injury; Aged; Anorexia; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Transitional Cell; Diarrhea; Fatigue; Female; Humans; Hyperphosphatemia; Hypoglycemia; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Piperazines; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; RNA, Messenger; Squamous Cell Carcinoma of Head and Neck; Thiophenes; Vomiting

2019
The neurokinin-2 receptor antagonist ibodutant improves overall symptoms, abdominal pain and stool pattern in female patients in a phase II study of diarrhoea-predominant IBS.
    Gut, 2017, Volume: 66, Issue:8

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Diarrhea; Dipeptides; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Quality of Life; Receptors, Neurokinin-2; Sex Factors; Symptom Assessment; Thiophenes; Young Adult

2017
Efficacy and safety of duloxetine in patients with chronic low back pain.
    Spine, 2010, Jun-01, Volume: 35, Issue:13

    Topics: Adult; Aged; Chronic Disease; Diarrhea; Double-Blind Method; Duloxetine Hydrochloride; Fatigue; Female; Humans; Low Back Pain; Male; Middle Aged; Nausea; Pain Measurement; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome

2010
Phase I and pharmacokinetic study of irinotecan in combination with raltitrexed.
    Cancer chemotherapy and pharmacology, 2002, Volume: 50, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Diarrhea; Drug Administration Schedule; Fatigue; Female; Humans; Irinotecan; Male; Middle Aged; Neoplasms; Neutropenia; Quinazolines; Thiophenes

2002
Raltitrexed plus radiotherapy for the treatment of unresectable/recurrent rectal cancer: a phase I study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Quinazolines; Rectal Neoplasms; Thiophenes

2003
Activity of raltitrexed and gemcitabine in advanced pancreatic cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Diarrhea; Disease Progression; Drug Administration Schedule; Female; Gemcitabine; Humans; Infusions, Intravenous; Male; Middle Aged; Nausea; Pancreatic Neoplasms; Quinazolines; Thiophenes; Treatment Outcome; Vomiting

2003
A phase I and pharmacokinetic study of irinotecan given as a 7-day continuous infusion in metastatic colorectal cancer patients pretreated with 5-fluorouracil or raltitrexed.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-01, Volume: 10, Issue:5

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Diarrhea; Female; Fluorouracil; Glucuronides; Humans; Infusions, Intravenous; Irinotecan; Male; Middle Aged; Nausea; Neoplasm Metastasis; Patient Selection; Quinazolines; Thiophenes; Vomiting

2004
A phase II study of raltitrexed and gemcitabine in patients with advanced pancreatic carcinoma.
    British journal of cancer, 2005, Feb-14, Volume: 92, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Diarrhea; Drug Administration Schedule; Female; Gemcitabine; Humans; Male; Middle Aged; Neutropenia; Pancreatic Neoplasms; Quinazolines; Survival Rate; Thiophenes

2005
First-line treatment with irinotecan and raltitrexed in metastatic colorectal cancer. Mature results of a multicenter phase II study.
    Oncology, 2005, Volume: 68, Issue:1

    Topics: Adult; Aged; Anemia; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asthenia; Camptothecin; Colorectal Neoplasms; Diarrhea; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Incidence; Irinotecan; Male; Middle Aged; Neutropenia; Quinazolines; Survival Analysis; Thiophenes; Treatment Outcome; Vomiting

2005
Duloxetine for the treatment of stress urinary incontinence in women: an integrated analysis of safety.
    European journal of obstetrics, gynecology, and reproductive biology, 2006, Mar-01, Volume: 125, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Constipation; Diarrhea; Disorders of Excessive Somnolence; Dizziness; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Fatigue; Female; Headache; Humans; Liver; Middle Aged; Nausea; Sleep Initiation and Maintenance Disorders; Thiophenes; Urinary Incontinence, Stress; Xerostomia

2006
Uridine diphosphate glucuronosyl transferase 1A1 promoter polymorphism predicts the risk of gastrointestinal toxicity and fatigue induced by irinotecan-based chemotherapy.
    Cancer, 2006, Mar-01, Volume: 106, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carbon-Nitrogen Ligases; Carcinoma; Colorectal Neoplasms; Diarrhea; Fatigue; Female; Genotype; Glucuronosyltransferase; Humans; Infusions, Intravenous; Irinotecan; Male; Middle Aged; Neutropenia; Polymorphism, Genetic; Predictive Value of Tests; Promoter Regions, Genetic; Quinazolines; Thiophenes; Thymidylate Synthase; Vomiting

2006
Phase I clinical and pharmacogenetic trial of irinotecan and raltitrexed administered every 21 days to patients with cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Oct-15, Volume: 19, Issue:20

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Diarrhea; Dose-Response Relationship, Drug; Fatigue; Female; Genotype; Homocysteine; Humans; Irinotecan; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasms; Neutropenia; Oxidoreductases Acting on CH-NH Group Donors; Quinazolines; Thiophenes

2001

Other Studies

19 other study(ies) available for thiophenes and Diarrhea

ArticleYear
Calcium-activated chloride channel is involved in the onset of diarrhea triggered by EGFR tyrosine kinase inhibitor treatment in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 141

    Topics: Acrylamides; Afatinib; Aniline Compounds; Animals; Chloride Channels; Diarrhea; ErbB Receptors; Feces; HEK293 Cells; Humans; Male; Patch-Clamp Techniques; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Thiophenes; Water

2021
Collagenous colitis and ileitis under treatment with duloxetine.
    Acta gastro-enterologica Belgica, 2012, Volume: 75, Issue:4

    Topics: Aged; Antidepressive Agents; Biopsy; Chronic Disease; Colitis, Collagenous; Colon; Colonoscopy; Depressive Disorder, Major; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Ileitis; Ileum; Recurrence; Thiophenes; Treatment Outcome; Withholding Treatment

2012
The safety of osteoporosis medication.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2014, Volume: 104, Issue:4

    Topics: Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Calcitonin; Calcium; Cardiovascular Diseases; Constipation; Diarrhea; Diphosphonates; Esophagitis; Estrogen Replacement Therapy; Fractures, Bone; Humans; Osteoporosis; Osteoporosis, Postmenopausal; Teriparatide; Thiophenes; Vitamin D

2014
Effects of Small Molecule Calcium-Activated Chloride Channel Inhibitors on Structure and Function of Accessory Cholera Enterotoxin (Ace) of Vibrio cholerae.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Animals; Chloride Channels; Cholera; Cholera Toxin; Circular Dichroism; Depsides; Diarrhea; Gallic Acid; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Recombinant Proteins; Spectrometry, Fluorescence; Tannins; Thiophenes; Vibrio cholerae

2015
Cevimeline.
    Drugs, 2008, Volume: 68, Issue:12

    Topics: Animals; Area Under Curve; Diarrhea; Female; Half-Life; Humans; Molecular Structure; Muscarinic Agonists; Nausea; Quinuclidines; Randomized Controlled Trials as Topic; Rhinitis; Sjogren's Syndrome; Sweating; Thiophenes; Treatment Outcome

2008
Oxaliplatin plus dual inhibition of thymidilate synthase during preoperative pelvic radiotherapy for locally advanced rectal carcinoma: long-term outcome.
    International journal of radiation oncology, biology, physics, 2011, Mar-01, Volume: 79, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Diarrhea; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Proteins; Neoplasm Staging; Neutropenia; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Preoperative Care; Prognosis; Quinazolines; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction; Thiophenes; Thymidylate Synthase; Treatment Outcome; Vitamin B Complex

2011
Duloxetine-induced lymphocytic colitis.
    Journal of clinical gastroenterology, 2012, Volume: 46, Issue:8

    Topics: Antidepressive Agents; Colitis, Lymphocytic; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Thiophenes

2012
Effects of combined polycarbophil-thihexinol and neomycin in acute diarrheas: experimental and clinical observations.
    Current therapeutic research, clinical and experimental, 1963, Volume: 5

    Topics: Acrylic Resins; Cyclohexanes; Diarrhea; Humans; Neomycin; Polymers; Thiophenes

1963
Etiology and treatment of diarrheas.
    Le Journal medical libanais. The Lebanese medical journal, 1962, Volume: 15

    Topics: Cyclohexanes; Diarrhea; Humans; Neomycin; Resins, Synthetic; Thiophenes

1962
DRUGS USED IN THE SYMPTOMATIC TREATMENT OF DIARRHEA.
    Canadian Medical Association journal, 1964, Oct-31, Volume: 91

    Topics: Cyclohexanes; Diarrhea; Drug Therapy; Humans; Kaolin; Opium; Parasympatholytics; Pectins; Piperidines; Psyllium; Thiophenes; Toxicology

1964
[TREATMENT OF ACUTE DIARRHEAS OF EARLY INFANCY WITH A COMBINATION OF THIOPHENICOL AND NEOMYCIN].
    Pediatria pratica, 1965, Volume: 36

    Topics: Diarrhea; Diarrhea, Infantile; Drug Therapy; Humans; Infant; Neomycin; Thiamphenicol; Thiophenes

1965
Open-label, long-term safety study of cevimeline in the treatment of postirradiation xerostomia.
    International journal of radiation oncology, biology, physics, 2007, Dec-01, Volume: 69, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Diarrhea; Dyspepsia; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Muscarinic Agonists; Nausea; Quinuclidines; Radiotherapy Dosage; Sweat; Thiophenes; Xerostomia

2007
Ticlopidine can cause chronic diarrhoea.
    Lancet (London, England), 1984, Feb-18, Volume: 1, Issue:8373

    Topics: Aged; Anticoagulants; Chronic Disease; Diarrhea; Humans; Male; Thiophenes; Ticlopidine

1984
Ticlopidine: quo vadis? Adverse reactions in man.
    Agents and actions. Supplements, 1984, Volume: 15

    Topics: Anticoagulants; Aspirin; Diarrhea; Humans; Neutropenia; Product Surveillance, Postmarketing; Thiophenes; Ticlopidine

1984
A comparison of ticlopidine and heparin on hemodialysis in dogs.
    The Journal of laboratory and clinical medicine, 1982, Volume: 100, Issue:6

    Topics: Animals; Anorexia; Diarrhea; Dogs; Heparin; Renal Dialysis; Thiophenes; Ticlopidine; Uremia

1982
Balb/c mice as a preclinical model for raltitrexed-induced gastrointestinal toxicity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Deoxyuridine; Diarrhea; Digestive System; Dose-Response Relationship, Drug; Folic Acid; Intestinal Mucosa; Intestine, Large; Intestine, Small; Male; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Weight Loss

2000
[Therapeutic trial of a drug combination (I.F.M.) in the treatment of non-specific diarrheas].
    Hospital (Rio de Janeiro, Brazil), 1970, Volume: 77, Issue:1

    Topics: Acetates; Adolescent; Adult; Amebicides; Amides; Clioquinol; Diarrhea; Female; Glycolates; Humans; Male; Middle Aged; Quaternary Ammonium Compounds; Thiophenes

1970
[New drug combination for the treatment of nonspecific acute diarrhea].
    Hospital (Rio de Janeiro, Brazil), 1970, Volume: 77, Issue:1

    Topics: Acetates; Adolescent; Adult; Amebicides; Child; Clioquinol; Diarrhea; Drug Synergism; Female; Gastrointestinal Agents; Glycolates; Humans; Male; Middle Aged; Quaternary Ammonium Compounds; Thiophenes

1970
Some indole and benzo[b]thiophene derivatives. Synthesis and pharmacology.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:6

    Topics: Analgesics; Animals; Behavior, Animal; Chemistry, Organic; Diarrhea; Ethylamines; In Vitro Techniques; Indoles; Liver; Mice; Monoamine Oxidase Inhibitors; Neoplasm Transplantation; Organic Chemistry Phenomena; Oxidation-Reduction; Quinones; Sarcoma 180; Serotonin; Thiophenes; Tremor

1966