thiophenes has been researched along with Diabetic Neuropathies in 97 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (1.03) | 18.7374 |
1990's | 6 (6.19) | 18.2507 |
2000's | 46 (47.42) | 29.6817 |
2010's | 44 (45.36) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Burgess, JR; Stochelski, MA; Walters, M; Wilmanski, T | 1 |
Bouhassira, D; Cruccu, G; Freynhagen, R; Lledo, A; Schacht, A; Skljarevski, V; Tesfaye, S; Tölle, T; Wilhelm, S | 1 |
Cai, N; Moore, RA; Skljarevski, V; Tölle, TR | 1 |
Finnerup, NB | 1 |
Itoh, M; Masuda, R; Suzuki, T | 1 |
Boulton, AJ; Dickenson, AH; Tesfaye, S | 1 |
Gupta, R; Koo, JY; Levin, E; Liao, W; Wu, JJ | 1 |
Anderson, SG; Dunn, G; Heald, AH; Malipatil, NS; Roberts, H | 1 |
Aoki, T; Hamakawa, N; Matsuoka, N; Murai, N; Tamura, S; Yamamoto, H | 1 |
Kato, F; Kinoshita, J; Takahashi, Y; Utsunomiya, K; Watabe, AM | 1 |
Cappelleri, JC; Chu, BC; Johnson, BH; Johnston, SS; Shrady, G; Silverman, SL; Udall, M | 1 |
Birklein, F; Boess, FG; Happich, M; Schacht, A; Schneider, E; Wilhelm, S; Ziegler, D | 1 |
Aldington, DJ; Kalso, E; Moore, RA | 1 |
Hughes, RA; Lunn, MP; Wiffen, PJ | 2 |
Engel, CC | 1 |
Callaghan, BC; Goutman, SA; Peltier, A | 1 |
Negi, G; Sharma, SS | 1 |
Hayashizaki, Y; Takakura, S; Takasu, T; Toyoshi, T | 1 |
Forde, G; Stanos, S | 1 |
Derry, S; Gaskell, H; Moore, RA; Sultan, A | 1 |
Culebras, A; Kelly, JJ | 1 |
Holloway, RG; Noyes, K; O'Connor, AB | 1 |
Edwards, SE; Hall, JA; Lipsius, S; McCarberg, BH; Meyers, AL; Ossanna, MJ; Raskin, J; Robinson, MJ; Wasan, AD; Wernicke, JF | 1 |
Chancellor, J; Garcia-Cebrian, A; Le, TK; Löthgren, M; Monz, B; Quilici, S; Said, G; Simon, D | 1 |
Bishnoi, M; Chopra, K; Kuhad, A | 1 |
Chappell, AS; Desaiah, D; Detke, MJ; Gross, JL; Skljarevski, V; Zhang, Q; Ziegler, D | 1 |
Kempler, P | 1 |
Ameri, AA | 1 |
Acharya, N; Crucitti, A; Hall, JA; Oakes, TM; Utterback, BG; Wang, F | 1 |
Hettinger, K; Lindsay, TJ; Rodgers, BC; Savath, V | 1 |
Boulanger, L; Chen, S; Fraser, K; Police, RL; Wu, N; Zhao, Y | 1 |
Brecht, S; Crucitti, A; Nilsson, M; Wernicke, J; Yang, CR; Zhang, Q | 1 |
Cao, Z; Fowler, R; Harnett, J; Mardekian, J; Margolis, J; Sanchez, RJ; Silverman, SL | 1 |
Cheng, LL; Desaiah, D; Gao, Y; Jia, WP; Li, Q; Liu, C; Liu, ZM; Ma, JH; Ning, G; Skljarevski, V; Wen, CY; Xu, ZR; Zhang, Q; Zhang, SY; Zhou, ZG | 1 |
Sun, P; Watson, P; Zhao, Y | 1 |
Duenas, H; Gaynor, P; McCarberg, B; Shoemaker, S; Zheng, W | 1 |
Bansal, D; Bhansali, A; Chakrabarti, A; Dutta, P; Hota, D; Kaur, H | 1 |
Jolivalt, CG; Mixcoatl-Zecuatl, T | 1 |
Boulanger, L; Chen, S; Fraser, K; Wu, N; Zhao, Y; Zhao, Z | 1 |
Burke, JP; Cappelleri, JC; Halpern, R; Joshi, AV; Kulakodlu, M; Sanchez, RJ | 1 |
Fleming, KF; Wu, JJ | 1 |
Ahl, J; Irving, GA; Malcolm, SK; Risser, RC; Robinson, MJ; Skljarevski, V; Tanenberg, RJ | 1 |
Fonseca, V; Liu, J; Shi, L; Thethi, T; Zhao, Y | 1 |
Emel'ianov, VV; Galkin, VV; Nesterova, MV | 1 |
Carlos, F; Dueñas, H; Galindo-Suárez, RM; Ramírez-Gámez, J; Ramos, E | 1 |
Bernauer, M; Sun, P; Watson, P; Zhao, Y; Zhao, Z | 1 |
Arslanian, A; Best, AE; Duan, RW; Nothaft, W; Pritchett, Y; Rowbotham, MC; Stacey, BR; Zhou, Q | 1 |
Granot, M; Granovsky, Y; Khamaisi, M; Nahman-Averbuch, H; Yarnitsky, D | 1 |
Bellows, BK; Biskupiak, J; Dahal, A; Jiao, T | 1 |
Langley, P; Nalamachu, S; Pergolizzi, JV; Raffa, RB; Rodriguez, G; Taylor, R | 1 |
Aarons, L; Bueno-Burgos, L; Gueorguieva, I; Iyengar, S; Yuen, E | 1 |
Boyle, J; Coppini, DV; Eriksson, ME; Gouni, R; Gribble, L; Johnsen, S; Kerr, D | 1 |
Crowell, K; Deluca, J; Page, N | 1 |
Bae, SK; Kim, EJ; Kim, HJ; Kim, SO; Kim, YG; Lee, DH; Lee, MG; Lim, H | 1 |
Gonzales, JS; Watkin, JG; Wohlreich, MM | 1 |
Delgado, PL | 1 |
Detke, MJ; Goldstein, DJ; Iyengar, S; Lee, TC; Lu, Y | 1 |
Gahimer, J; Viktrup, L; Wernicke, JF; Wulster-Radcliffe, M; Yalcin, I | 1 |
Gayken, J; Haight, R; Westanmo, AD | 1 |
D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Smith, TR; Wernicke, JF; Wong, K | 1 |
Smith, TR | 1 |
Birnbaum, HG; Gelwicks, S; Le, TK; Mareva, MN; Robinson, RL; Rosen, A; Wu, EQ | 1 |
Russell, JW | 1 |
Desaiah, D; Perahia, DG; Pritchett, YL; Raskin, J | 1 |
D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Tran, P; Waninger, A; Wernicke, JF | 1 |
O'Connor, AB | 1 |
Ziegler, D | 1 |
Armbruster, M; Boulton, AJ; Hardy, T; Sachson, R; Shen, S | 1 |
Gahimer, J; Ossanna, MJ; Viktrup, L; Wernicke, J; Wulster-Radcliffe, M; Yalcin, I | 1 |
Chappell, AS; Desaiah, D; Hall, JA; Pritchett, YL; Robinson, MJ; Wang, F; Ziegler, D | 1 |
Terneus, W | 1 |
Kajdasz, DK; Lledó, A; Raskin, J; Wang, F; Wernicke, J | 1 |
Kempler, P; Várkonyi, T | 1 |
Kirby, M; Thor, KB; Viktrup, L | 1 |
Michel, MC | 1 |
Baglioni, P; Govindan, J; Khan, A | 1 |
Cole, BE | 1 |
Armstrong, DG; Wrobel, JS; Wu, SC | 1 |
Robinson-Papp, J; Simpson, DM | 1 |
Chappell, AS; D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Smith, TR; Wang, F; Wernicke, JF | 1 |
Beard, SM; Garcia-Cebrian, A; Le, TK; Malik, RA; McCrink, L; Monz, B | 1 |
Backonja, MM; Desaiah, D; Farrar, JT; Fishbain, DA; Iyengar, S; Jensen, TS; Kajdasz, DK; McQuay, HJ; Rowbotham, MC; Sang, CN; Ziegler, D | 1 |
Nicholson, RA; Smith, T | 1 |
Fishbain, DA; Gonzales, J; Hall, J; Mallinckrodt, C; Meyers, AL | 1 |
Mirouze, J | 1 |
Hamada, Y; Hara, T; Inukai, S; Koh, N; Nakamura, J; Nakashima, E; Naruse, K; Sakakibara, F; Sasaki, H; Takeuchi, N | 1 |
Fukasawa, H; Hamada, Y; Hara, T; Hotta, N; Kakuta, H; Koh, N; Mori, K; Nakamura, J; Sakakibara, F; Wakao, T | 1 |
Agata, M; Goto, M; Inukai, S; Matsukawa, H; Naitou, A; Sato, M | 1 |
Hamada, Y; Hara, T; Hotta, N; Koh, N; Mori, K; Nakamura, J; Nakashima, E; Naruse, K; Sakakibara, F; Sakamoto, N; Wakao, T | 1 |
Hamada, Y; Hotta, N; Koh, N; Mori, K; Nakamura, J; Nakashima, E; Naruse, K; Sakakibara, F; Sasaki, H; Wakao, T | 1 |
Chaya, S; Hamada, Y; Hara, T; Hotta, N; Kasuya, Y; Kato, K; Koh, N; Komori, T; Nakamura, J; Nakashima, E; Naruse, K; Sakakibara, F; Sasaki, H; Takeuchi, N | 1 |
Hamada, Y; Hara, T; Hotta, N; Kamijo, M; Koh, N; Mori, K; Nakamura, J; Nakashima, E; Naruse, K; Sakakibara, F; Wakao, T | 1 |
27 review(s) available for thiophenes and Diabetic Neuropathies
Article | Year |
---|---|
Mechanisms and management of diabetic painful distal symmetrical polyneuropathy.
Topics: Diabetic Neuropathies; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Pain; Peripheral Nervous System Diseases; Pregabalin; Thiophenes | 2013 |
Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia.
Topics: Adult; Analgesics; Chronic Pain; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Neuralgia; Randomized Controlled Trials as Topic; Thiophenes | 2014 |
Painful diabetic neuropathy.
Topics: Amines; Analgesics; Analgesics, Opioid; Biopsy; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoglycemic Agents; Pregabalin; Sensory Thresholds; Skin; Thiophenes; Touch Perception | 2014 |
Practical management strategies for the chronic pain patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Antidepressive Agents, Tricyclic; Carbamazepine; Chronic Disease; Clinical Protocols; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Monitoring; Drug Tolerance; Duloxetine Hydrochloride; Family Practice; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Middle Aged; Pain; Practice Guidelines as Topic; Pregabalin; Randomized Controlled Trials as Topic; Substance-Related Disorders; Thiophenes; Treatment Outcome | 2007 |
Duloxetine for painful diabetic neuropathy and fibromyalgia pain: systematic review of randomised trials.
Topics: Adrenergic Uptake Inhibitors; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2008 |
Meta-analysis of duloxetine vs. pregabalin and gabapentin in the treatment of diabetic peripheral neuropathic pain.
Topics: Amines; Analgesics; Analysis of Variance; Bayes Theorem; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Peripheral Nervous System; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2009 |
Duloxetine for treating painful neuropathy or chronic pain.
Topics: Analgesics; Chronic Disease; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Randomized Controlled Trials as Topic; Thiophenes | 2009 |
Safety and tolerability of duloxetine in the acute management of diabetic peripheral neuropathic pain: analysis of pooled data from three placebo-controlled clinical trials.
Topics: Adrenergic Uptake Inhibitors; Chronic Disease; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Polypharmacy; Randomized Controlled Trials as Topic; Thiophenes | 2010 |
Treating diabetic peripheral neuropathic pain.
Topics: Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Complementary Therapies; Diabetic Neuropathies; Drug Interactions; Drug Therapy, Combination; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Pain; Pain Measurement; Pregabalin; Recovery of Function; Thiophenes | 2010 |
Duloxetine treatment and glycemic controls in patients with diagnoses other than diabetic peripheral neuropathic pain: a meta-analysis.
Topics: Antidepressive Agents; Anxiety Disorders; Blood Glucose; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Glycemic Index; Humans; Hyperglycemia; Male; Middle Aged; Mood Disorders; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2010 |
Weight change with long-term duloxetine use in chronic painful conditions: an analysis of 16 clinical studies.
Topics: Aged; Analgesics; Arthralgia; Chronic Disease; Controlled Clinical Trials as Topic; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Knee Joint; Low Back Pain; Male; Middle Aged; Osteoarthritis, Knee; Pain; Thiophenes; Weight Gain; Weight Loss | 2011 |
A review of duloxetine 60 mg once-daily dosing for the management of diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain due to chronic osteoarthritis pain and low back pain.
Topics: Analgesics; Chronic Pain; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Low Back Pain; Musculoskeletal Pain; Osteoarthritis; Thiophenes | 2013 |
Clinical inquiry: what medications are best for diabetic neuropathic pain?
Topics: Amines; Analgesics; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Practice Guidelines as Topic; Thiophenes | 2012 |
Common pathways of depression and pain.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Brain; Chronic Disease; Cyclohexanols; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Norepinephrine; Pain; Recurrence; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Venlafaxine Hydrochloride | 2004 |
Safety and adverse event profile of duloxetine.
Topics: Cytochrome P-450 Enzyme System; Depressive Disorder, Major; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Half-Life; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2005 |
Duloxetine: a balanced and selective norepinephrine- and serotonin-reuptake inhibitor.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Area Under Curve; Depressive Disorder; Diabetic Neuropathies; Drug Interactions; Duloxetine Hydrochloride; Formularies as Topic; Humans; Liver Failure; Randomized Controlled Trials as Topic; Renal Insufficiency; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence | 2005 |
Duloxetine in diabetic neuropathy.
Topics: Diabetic Neuropathies; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2006 |
Efficacy of duloxetine in painful symptoms: an analgesic or antidepressant effect?
Topics: Analgesics; Antidepressive Agents; Chronic Disease; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Thiophenes; Treatment Outcome | 2006 |
[Duloxetine, a new therapeutic option for diabetic peripheral neuropathic pain].
Topics: Adrenergic Uptake Inhibitors; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Quality of Life; Risk Factors; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2006 |
Is there a place for duloxetine?
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder; Diabetic Neuropathies; Drug Costs; Drug Interactions; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2007 |
An evaluation of the cardiovascular safety profile of duloxetine: findings from 42 placebo-controlled studies.
Topics: Adrenergic Uptake Inhibitors; Anxiety Disorders; Cardiovascular Diseases; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Placebos; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence | 2007 |
Diabetic neuropathy: new strategies for treatment.
Topics: Aldehyde Reductase; Amines; Analgesics; Anticonvulsants; Antidepressive Agents; Antioxidants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Thiamine; Thioctic Acid; Thiophenes | 2008 |
Serotonin and noradrenaline involvement in urinary incontinence, depression and pain: scientific basis for overlapping clinical efficacy from a single drug, duloxetine.
Topics: Antidepressive Agents; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Humans; Male; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2007 |
Diabetic peripheral neuropathic pain: recognition and management.
Topics: Antidepressive Agents; Diabetic Foot; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Thiophenes | 2007 |
Assessing the impact of pharmacologic intervention on the quality of life in diabetic peripheral neuropathic pain and fibromyalgia.
Topics: Antidepressive Agents; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Pain; Pregabalin; Quality of Life; Randomized Controlled Trials as Topic; Thiophenes | 2007 |
Safety profile of treatment in diabetic peripheral neuropathic pain.
Topics: Administration, Topical; Analgesics; Anesthetics, Local; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Capsaicin; Cyclohexanols; Diabetic Neuropathies; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Pain; Pregabalin; Thiophenes; Venlafaxine Hydrochloride | 2007 |
Review of duloxetine in the management of diabetic peripheral neuropathic pain.
Topics: Clinical Trials as Topic; Diabetic Neuropathies; Drug Interactions; Duloxetine Hydrochloride; Humans; Molecular Structure; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
19 trial(s) available for thiophenes and Diabetic Neuropathies
Article | Year |
---|---|
Duloxetine and pregabalin: high-dose monotherapy or their combination? The "COMBO-DN study"--a multinational, randomized, double-blind, parallel-group study in patients with diabetic peripheral neuropathic pain.
Topics: Aged; Analgesics; Diabetic Neuropathies; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Internationality; Male; Middle Aged; Pain; Pregabalin; Thiophenes; Treatment Outcome | 2013 |
Duloxetine use in chronic painful conditions--individual patient data responder analysis.
Topics: Antidepressive Agents; Chronic Pain; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Fibromyalgia; Humans; Individuality; Low Back Pain; Osteoarthritis; Pain Measurement; Thiophenes; Treatment Outcome | 2014 |
Evaluating the maintenance of effect of duloxetine in patients with diabetic peripheral neuropathic pain.
Topics: Adrenergic Uptake Inhibitors; Aged; Confidence Intervals; Diabetic Neuropathies; Drug Monitoring; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Thiophenes; Time Factors; Treatment Outcome | 2009 |
Duloxetine versus placebo in the treatment of patients with diabetic neuropathic pain in China.
Topics: Adrenergic Uptake Inhibitors; Aged; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Placebos; Thiophenes; Treatment Outcome | 2010 |
A comparative evaluation of amitriptyline and duloxetine in painful diabetic neuropathy: a randomized, double-blind, cross-over clinical trial.
Topics: Adolescent; Adult; Aged; Amitriptyline; Cross-Over Studies; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Young Adult | 2011 |
Duloxetine, pregabalin, and duloxetine plus gabapentin for diabetic peripheral neuropathic pain management in patients with inadequate pain response to gabapentin: an open-label, randomized, noninferiority comparison.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Pregabalin; Thiophenes; Treatment Outcome | 2011 |
[Biological age and the pain syndrome at diabetic polyneuropathy].
Topics: Adult; Aging; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Selective Serotonin Reuptake Inhibitors; Syndrome; Thiophenes; Treatment Outcome | 2011 |
Efficacy and safety of the α4β2 neuronal nicotinic receptor agonist ABT-894 in patients with diabetic peripheral neuropathic pain.
Topics: Aged; Azabicyclo Compounds; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Nicotinic Agonists; Pain Measurement; Pyridines; Receptors, Nicotinic; Thiophenes; Treatment Outcome | 2012 |
Conditioned pain modulation predicts duloxetine efficacy in painful diabetic neuropathy.
Topics: Aged; Analgesics; Conditioning, Psychological; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Pain Threshold; Predictive Value of Tests; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2012 |
Population pharmacokinetic/pharmacodynamic models for duloxetine in the treatment of diabetic peripheral neuropathic pain.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Analgesics; Diabetic Neuropathies; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Logistic Models; Male; Middle Aged; Models, Statistical; Nonlinear Dynamics; Pain Measurement; Patient Dropouts; Sex Factors; Socioeconomic Factors; Thiophenes; Young Adult | 2013 |
Randomized, placebo-controlled comparison of amitriptyline, duloxetine, and pregabalin in patients with chronic diabetic peripheral neuropathic pain: impact on pain, polysomnographic sleep, daytime functioning, and quality of life.
Topics: Aged; Amitriptyline; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pregabalin; Quality of Life; Sleep; Thiophenes; Treatment Outcome | 2012 |
Duloxetine vs. placebo in patients with painful diabetic neuropathy.
Topics: Aged; Demography; Depression; Diabetic Neuropathies; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain Measurement; Personality Inventory; Placebos; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2005 |
Duloxetine versus routine care in the long-term management of diabetic peripheral neuropathic pain.
Topics: Amines; Amitriptyline; Analysis of Variance; Cyclohexanecarboxylic Acids; Cyclohexanols; Diabetic Neuropathies; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2006 |
Cost-effectiveness of duloxetine versus routine treatment for U.S. patients with diabetic peripheral neuropathic pain.
Topics: Adrenergic Uptake Inhibitors; Aged; Amines; Amitriptyline; Analgesia; Analgesics; Brain; Cohort Studies; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Cyclohexanols; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Norepinephrine; Pain Measurement; Pain Threshold; Placebo Effect; Serotonin; Thiophenes; Treatment Outcome; United States; Venlafaxine Hydrochloride | 2006 |
A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain.
Topics: Acetaminophen; Adrenergic Uptake Inhibitors; Aged; Analgesics, Non-Narcotic; Diabetic Neuropathies; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Norepinephrine; Pain; Palliative Care; Peripheral Nervous System Diseases; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome | 2006 |
Impact of disease characteristics on the efficacy of duloxetine in diabetic peripheral neuropathic pain.
Topics: Adrenergic Uptake Inhibitors; Aged; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Humans; Least-Squares Analysis; Middle Aged; Neuritis; Pain Measurement; Placebos; Racial Groups; Safety; Thiophenes; Treatment Outcome | 2007 |
An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.
Topics: Acetaminophen; Amitriptyline; Analgesics; Carbamazepine; Diabetes Complications; Diabetic Neuropathies; Diclofenac; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Lipids; Male; Meloxicam; Middle Aged; Neuralgia; Pentoxifylline; Selective Serotonin Reuptake Inhibitors; Thiamine; Thiazines; Thiazoles; Thioctic Acid; Thiophenes; Time; Vitamin B 12 | 2007 |
Duloxetine for the management of diabetic peripheral neuropathic pain: evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Peripheral Nervous System Diseases; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
Ticlopidine in the secondary prevention of early diabetes-related microangiopathy: protocol of a multicenter therapeutic study (TIMAD study).
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Anticoagulants; Brain Ischemia; Clinical Trials as Topic; Diabetic Angiopathies; Diabetic Neuropathies; Diabetic Retinopathy; Electrocardiography; Fluorescein Angiography; Follow-Up Studies; Humans; Middle Aged; Patient Compliance; Platelet Aggregation; Thiophenes; Ticlopidine | 1984 |
51 other study(ies) available for thiophenes and Diabetic Neuropathies
Article | Year |
---|---|
D3T acts as a pro-oxidant in a cell culture model of diabetes-induced peripheral neuropathy.
Topics: Antioxidants; Cell Line, Tumor; Cell Survival; Dehydroepiandrosterone; Diabetic Neuropathies; Glutathione; Glutathione Transferase; Glycation End Products, Advanced; Humans; Models, Biological; Neurites; Oxidative Stress; Thiones; Thiophenes | 2019 |
Add-on therapy: when two are not better than one.
Topics: Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Male; Pain; Pregabalin; Thiophenes | 2013 |
[Duloxetine for chronic pain management: pharmacology and clinical use].
Topics: Adrenergic Uptake Inhibitors; Chronic Pain; Depression; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Thiophenes | 2013 |
Possible drug-drug interaction between adalimumab and duloxetine and/or pregabalin in a psoriasis patient.
Topics: Adalimumab; Analgesics; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antidepressive Agents; Biological Products; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Drug Interactions; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Pregabalin; Psoriasis; Thiophenes; Young Adult | 2013 |
Socioeconomic deprivation independently predicts symptomatic painful diabetic neuropathy in type 1 diabetes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Biomarkers; Body Mass Index; Chi-Square Distribution; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Duloxetine Hydrochloride; England; Female; Glycated Hemoglobin; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Poverty; Prevalence; Risk Assessment; Risk Factors; Severity of Illness Index; Thiophenes; Young Adult | 2014 |
AS1069562, the (+)-isomer of indeloxazine, but not duloxetine has a curative-like analgesic effect in a rat model of streptozotocin-induced diabetic neuropathy.
Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibroblast Growth Factor 2; Ganglia, Spinal; Hyperalgesia; Insulin-Like Growth Factor I; Male; Morpholines; Neural Conduction; Neurotransmitter Uptake Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Streptozocin; Thiophenes; Time Factors | 2014 |
Impaired noradrenaline homeostasis in rats with painful diabetic neuropathy as a target of duloxetine analgesia.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochloride; Male; Norepinephrine; Rats; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2013 |
Cost comparison of drug-drug and drug-condition interactions in patients with painful diabetic peripheral neuropathy treated with pregabalin versus duloxetine.
Topics: Aged; Analgesics; Cohort Studies; Databases, Factual; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Health Care Costs; Humans; Male; Middle Aged; Pregabalin; Retrospective Studies; Thiophenes; United States | 2013 |
Effectiveness of duloxetine compared with pregabalin and gabapentin in diabetic peripheral neuropathic pain: results from a German observational study.
Topics: Aged; Amines; Analgesics; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Health Surveys; Humans; Male; Middle Aged; Pain Measurement; Pregabalin; Prospective Studies; Thiophenes; Treatment Outcome | 2014 |
Drugs for neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pregabalin; Thiophenes; Treatment Outcome | 2013 |
ACP Journal Club. Review: In neuropathy, fibromyalgia, or chronic pain, duloxetine reduces pain but increases adverse events.
Topics: Analgesics; Chronic Pain; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Neuralgia; Thiophenes | 2014 |
Inhibition of IκB kinase (IKK) protects against peripheral nerve dysfunction of experimental diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; I-kappa B Kinase; Male; Neural Conduction; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Thiophenes | 2015 |
Effect of ipragliflozin, an SGLT2 inhibitor, on progression of diabetic microvascular complications in spontaneously diabetic Torii fatty rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Progression; Glucosides; Hyperglycemia; Hypoglycemic Agents; Male; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2016 |
Sleep disorders and neuromuscular diseases.
Topics: Administration, Cutaneous; Brain Injuries; Continuous Positive Airway Pressure; Copper; Diabetic Neuropathies; Dopamine Agonists; Humans; Ischemic Attack, Transient; Myasthenia Gravis; Neuromuscular Diseases; Peripheral Nervous System Diseases; Restless Legs Syndrome; Sleep Apnea Syndromes; Sleep Wake Disorders; Stroke; Tetrahydronaphthalenes; Thiophenes | 2008 |
A cost-utility comparison of four first-line medications in painful diabetic neuropathy.
Topics: Amines; Analgesics; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Desipramine; Diabetic Neuropathies; Duloxetine Hydrochloride; Economics, Pharmaceutical; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pregabalin; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Thiophenes | 2008 |
Safety and efficacy of duloxetine in the treatment of diabetic peripheral neuropathic pain in older patients.
Topics: Age Factors; Aged; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2009 |
Anti-nociceptive effect of duloxetine in mouse model of diabetic neuropathic pain.
Topics: Adenosine; Animals; Cerebral Cortex; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Pain Measurement; Pain Threshold; Selective Serotonin Reuptake Inhibitors; Streptozocin; Thiophenes; Touch | 2009 |
[Treatment of neuropathies].
Topics: Adjuvants, Immunologic; Adrenergic Uptake Inhibitors; Amines; Analgesics; Antioxidants; Capsaicin; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Polyneuropathies; Pregabalin; Sensory System Agents; Thiamine; Thioctic Acid; Thiophenes | 2010 |
[Expel the fear of pain. Breaking of chronicity by re-learning].
Topics: Analgesics; Clinical Trials as Topic; Diabetic Neuropathies; Duloxetine Hydrochloride; Fear; Humans; Pain; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome | 2009 |
Changes in opioid use and healthcare costs among U.S. patients with diabetic peripheral neuropathic pain treated with duloxetine compared with other therapies.
Topics: Adolescent; Adult; Analgesics; Analgesics, Opioid; Diabetic Neuropathies; Drug Substitution; Duloxetine Hydrochloride; Female; Health Care Costs; Humans; Male; Middle Aged; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; United States; Young Adult | 2010 |
Evaluation of healthcare resource utilization and costs in employees with pain associated with diabetic peripheral neuropathy treated with pregabalin or duloxetine.
Topics: Adolescent; Adult; Age Factors; Analgesics; Comorbidity; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Health Services; Humans; Insurance Claim Review; Male; Middle Aged; Pain; Pregabalin; Sex Factors; Socioeconomic Factors; Thiophenes; Young Adult | 2010 |
Medication adherence and healthcare costs among patients with diabetic peripheral neuropathic pain initiating duloxetine versus pregabalin.
Topics: Adolescent; Adult; Analgesics; Cohort Studies; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Health Care Costs; Humans; Male; Medication Adherence; Middle Aged; Neuralgia; Pregabalin; Retrospective Studies; Thiophenes; Young Adult | 2011 |
A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy.
Topics: Amphetamines; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Hyperalgesia; Ketanserin; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Thiophenes | 2011 |
Factors associated with pain medication selection among patients diagnosed with diabetic peripheral neuropathic pain: a retrospective study.
Topics: Analgesics; Comorbidity; Costs and Cost Analysis; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Health Services; Humans; Insurance Claim Review; Male; Middle Aged; Pain; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Socioeconomic Factors; Thiophenes; United States | 2011 |
Health care costs in patients with painful diabetic peripheral neuropathy prescribed pregabalin or duloxetine.
Topics: Adolescent; Adult; Aged; Analgesics; Cohort Studies; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Health Care Costs; Health Services; Humans; Male; Managed Care Programs; Middle Aged; Pregabalin; Thiophenes; United States | 2012 |
Interaction between adalimumab with concurrent pregabalin and duloxetine administration in a psoriasis patient with diabetic peripheral neuropathy.
Topics: Adalimumab; Analgesics; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Drug Interactions; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Pregabalin; Psoriasis; Selective Serotonin Reuptake Inhibitors; Thiophenes; Young Adult | 2011 |
Predictors of duloxetine versus other treatments among veterans with diabetic peripheral neuropathic pain: a retrospective study.
Topics: Aged; Analgesics; Antidepressive Agents; Cohort Studies; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Retrospective Studies; Thiophenes; Veterans | 2012 |
Economic evaluation of duloxetine as a first-line treatment for painful diabetic peripheral neuropathy in Mexico.
Topics: Amines; Analgesics; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dopamine Uptake Inhibitors; Drug Costs; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Mexico; Pregabalin; Thiophenes | 2012 |
Dosing pattern comparison between duloxetine and pregabalin among patients with diabetic peripheral neuropathic pain.
Topics: Analgesics; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Practice Patterns, Physicians'; Pregabalin; Thiophenes | 2012 |
A cost-utility analysis of pregabalin versus duloxetine for the treatment of painful diabetic neuropathy.
Topics: Analgesics; Antidepressive Agents; Clinical Trials as Topic; Cost-Benefit Analysis; Decision Trees; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Approval; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Models, Economic; Pregabalin; Quality-Adjusted Life Years; Thiophenes; United States; United States Food and Drug Administration | 2012 |
Dose-independent pharmacokinetics of a candidate for diabetic neuropathy, SR-4668, after intravenous and oral administration to rats: Intestinal first-pass effect.
Topics: Administration, Oral; Animals; Area Under Curve; Bile; Chromatography, High Pressure Liquid; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Stability; Gastric Juice; Gastric Mucosa; Half-Life; Injections, Intravenous; Intestinal Mucosa; Liver; Male; Peripheral Nervous System Agents; Rats; Rats, Sprague-Dawley; Thiophenes; Time Factors; Tissue Distribution | 2003 |
Duloxetine's role in the treatment of depression and associated painful physical symptoms.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Thiophenes; Treatment Outcome | 2004 |
Molecule of the month. Duloxetine hydrochloride.
Topics: Adult; Diabetic Neuropathies; Drug Administration Schedule; Duloxetine Hydrochloride; Fibromyalgia; Humans; Multicenter Studies as Topic; Thiophenes; Time Factors | 2004 |
[Duloxetine receives positive recommendation by the Scientific Committee of EMEA for treatment of depression].
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder, Major; Diabetic Neuropathies; Drug Approval; Duloxetine Hydrochloride; Europe; Humans; Pharmacy and Therapeutics Committee; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2004 |
Does duloxetine safely and effectively reduce the severity of diabetic peripheral neuropathic pain?
Topics: Antidepressive Agents; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Humans; Multicenter Studies as Topic; Pain; Pain Measurement; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2006 |
Cost-effectiveness of duloxetine versus routine treatment for U.S. patients with diabetic peripheral neuropathic pain.
Topics: Antidepressive Agents; Cost-Benefit Analysis; Diabetic Neuropathies; Drug Costs; Duloxetine Hydrochloride; Humans; Pain; Thiophenes | 2006 |
Duloxetine: new indication. Depression and diabetic neuropathy: too many adverse effects.
Topics: Adult; Depression; Diabetic Neuropathies; European Union; Female; Fibromyalgia; Humans; Male; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2006 |
Does treatment with duloxetine for neuropathic pain impact glycemic control?
Topics: Adult; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Glycated Hemoglobin; Humans; Lipids; Male; Middle Aged; Neuritis; Placebos; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
A retrospective pooled analysis of duloxetine safety in 23,983 subjects.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anxiety Disorders; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Prevalence; Retrospective Studies; Thiophenes; United States; Urinary Incontinence, Stress | 2007 |
Pregabalin and duloxetine for the treatment of neuropathic pain disorders.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes | 2007 |
Duloxetine--three birds with one stone?
Topics: Antidepressive Agents; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2007 |
Career lifetime advances and key developments: diabetes.
Topics: Amines; Amitriptyline; Analgesics; Antidepressive Agents; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Thiophenes | 2007 |
Cost effectiveness of duloxetine in the treatment of diabetic peripheral neuropathic pain in the UK.
Topics: Amines; Amitriptyline; Antidepressive Agents; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Econometric; Paclitaxel; Pain Measurement; Prospective Studies; Quality-Adjusted Life Years; Sickness Impact Profile; Thiophenes; Treatment Outcome; United Kingdom | 2008 |
Does pain mediate the pain interference with sleep problem in chronic pain? Findings from studies for management of diabetic peripheral neuropathic pain with duloxetine.
Topics: Antidepressive Agents; Chronic Disease; Comorbidity; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Incidence; Male; Middle Aged; Pain; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Thiophenes; Treatment Outcome; United States | 2008 |
An aldose reductase inhibitor, TAT, reduces ADP-induced platelet hyperaggregation in streptozotocin-induced diabetic rats with neuropathy.
Topics: Adenosine Diphosphate; Aldehyde Reductase; Ampholyte Mixtures; Animals; Blood Glucose; Blood Platelets; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Enzyme Inhibitors; Male; Neural Conduction; Platelet Aggregation; Polymers; Rats; Rats, Wistar; Sciatic Nerve; Streptozocin; Tetrazoles; Thiophenes | 1995 |
Effect of a potent new aldose reductase inhibitor, (5-(3-thienyltetrazol-1-yl)acetic acid (TAT), on diabetic neuropathy in rats.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Erythrocytes; Fructose; Glucose; Inositol; Male; Motor Neurons; Neural Conduction; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Reference Values; Regional Blood Flow; Regression Analysis; Sciatic Nerve; Sorbitol; Tail; Tetrazoles; Thiophenes; Time Factors | 1995 |
Characterization of a novel aldose reductase inhibitor, TAT, and its effects on streptozotocin-induced diabetic neuropathy in rats.
Topics: Aldehyde Reductase; Animals; Diabetic Neuropathies; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Neural Conduction; Rabbits; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sorbitol; Sugar Alcohols; Tetrazoles; Thiophenes | 1993 |
Effect of propionyl-L-carnitine on motor nerve conduction, autonomic cardiac function, and nerve blood flow in rats with streptozotocin-induced diabetes: comparison with an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Carbohydrate Metabolism; Cardiotonic Agents; Carnitine; Cauda Equina; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Electrocardiography; Enzyme Inhibitors; Heart Conduction System; Lipids; Male; Motor Neurons; Neural Conduction; Rats; Rats, Wistar; Sciatic Nerve; Tetrazoles; Thiophenes | 1996 |
Diabetic neuropathy in sucrose-fed Otsuka Long-Evans Tokushima fatty rats: effect of an aldose reductase inhibitor, TAT.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Models, Animal; Enzyme Inhibitors; Insulin; Lipids; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymers; Rats; Regional Blood Flow; Sciatic Nerve; Sucrose; Tetrazoles; Thiophenes | 1997 |
Polyol pathway hyperactivity is closely related to carnitine deficiency in the pathogenesis of diabetic neuropathy of streptozotocin-diabetic rats.
Topics: Acetylcarnitine; Aldehyde Reductase; Animals; Body Weight; Carnitine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Enzyme Inhibitors; Hemodynamics; Male; Neural Conduction; Polymers; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Tetrazoles; Thiophenes | 1998 |
Physiological and morphometric analyses of neuropathy in sucrose-fed OLETF rats.
Topics: 2,3-Diphosphoglycerate; Aldehyde Reductase; Animals; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Dietary Sucrose; Enzyme Inhibitors; Erythrocytes; Humans; Hyperglycemia; Male; Neural Conduction; Platelet Aggregation; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Regional Blood Flow; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Tetrazoles; Thiophenes | 2001 |