thiophenes has been researched along with Diabetic Glomerulosclerosis in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.03) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (12.12) | 29.6817 |
| 2010's | 23 (69.70) | 24.3611 |
| 2020's | 5 (15.15) | 2.80 |
| Authors | Studies |
|---|---|
| Takakura, S; Takasu, T | 1 |
| Inoue, T; Kusakabe, T; Odori, S; Satoh-Asahara, N; Shimatsu, A; Tanaka, M; Yamakage, H | 1 |
| Amemiya, H; Asakura, T; Iemitsu, K; Ishikawa, M; Ito, S; Kanamori, A; Kaneshiro, M; Kawata, T; Kubota, A; Machimura, H; Matsuba, I; Matsuzawa, Y; Minagawa, F; Minami, N; Miyakawa, M; Mokubo, A; Shinoda, K; Takai, M; Takeda, H; Takihata, M; Takuma, T; Tanaka, K; Tanaka, Y; Terauchi, Y | 1 |
| Bian, M; Ding, L; Jiang, Z; Li, D; Wu, J; Zeng, Q | 1 |
| Hong, S; Ke, R; Wang, Y; Xiao, L | 1 |
| Mori, K; Nakamura, S; Ogawa, Y; Okuma, H; Sekine, T; Tsuchiya, K | 1 |
| Gaikwad, AB; Pandey, A | 1 |
| Ahad, A; Ahmad, A; Al-Jenoobi, FI; Al-Mohizea, AM; Raish, M | 1 |
| Tahara, A; Takasu, T | 2 |
| Chen, R; Cheng, O; Ding, S; Huang, B; Huang, J; Jiang, Q; Qiu, H; Zhang, J | 1 |
| Gilbert, RE | 1 |
| Scheen, AJ | 1 |
| Seufert, J | 1 |
| Bakris, G; Cariou, B; David-Neto, E; Figueroa, K; Jiang, J; Law, G; Meininger, G; Nieto, J; Usiskin, K; Wajs, E; Yale, JF; Yue, D | 1 |
| Bakris, G; Davies, M; de Zeeuw, D; Kline, I; Mayer, C; Meininger, G; Perkovic, V; Usiskin, K; Vijapurkar, U; Woo, V; Yamout, H | 1 |
| Bombardi, C; Carletti, R; Castoldi, G; Dahlöf, B; di Gioia, CR; Maestroni, S; Steckelings, UM; Stella, A; Unger, T; Zerbini, G | 1 |
| Hanefeld, M; Herz, M; Lincoff, AM; Malmberg, K; Meyer-Reigner, S; Mudie, N; Ruilope, L; Viberti, G; Wieczorek Kirk, D | 1 |
| Cherney, DZ; Škrtić, M | 1 |
| Heeba, GH; Mahmoud, ME; Morsy, MA | 1 |
| Bakris, GL; Majewski, C | 1 |
| Allen, TJ; Chow, BS; Cooper, ME; Jandeleit-Dahm, KA; Koulis, C; McKelvey, M; Steckelings, UM; Thallas-Bonke, V; Thomas, MC; Unger, T | 1 |
| Hayashizaki, Y; Takakura, S; Takasu, T; Toyoshi, T | 1 |
| Harada, M; Kawamura, T; Miyazaki, Y; Nakayama, I; Ogura, M; Okonogi, H; Sato, H; Tokoro, K; Tsuboi, N; Yokoo, T | 1 |
| Bledsoe, SL; Boulanger, L; Chen, S; Fraser, K; Wu, N; Zhao, Y | 1 |
| Awad, AS; Bolton, WK; Huang, L; Khutsishvili, K; Lynch, KR; Okusa, MD; Rouse, MD | 1 |
| Atzpodien, EA; Bénardeau, A; Funk, JM; Meyer, M; Mizrahi, J; Sebokova, E; Uhles, S; Verry, P; Winter, M; Wright, MB | 1 |
| Komala, MG; Mather, A; Panchapakesan, U; Pollock, C | 1 |
| Kohan, DE; Pollock, DM | 1 |
| Ivanova, NA; Preobrazhenskiĭ, DV; Sidorenko, BA; Soplevenko, AV; Stetsenko, TM | 1 |
| D'Arrigo, T | 1 |
| Aurell, M; Blohmé, G; Jagenburg, R; Larsson, O; Nyberg, G; Westberg, NG | 1 |
| Hollenberg, NK; Laffel, LM; Lansang, MC; Osei, SY; Price, DA | 1 |
8 review(s) available for thiophenes and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
AT
Topics: Diabetic Nephropathies; Humans; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes | 2017 |
Sodium-glucose linked transporter-2 inhibitors: potential for renoprotection beyond blood glucose lowering?
Topics: Animals; Benzhydryl Compounds; Blood Pressure; Canagliflozin; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glomerular Filtration Rate; Glucose; Glucosides; Humans; Hypoglycemic Agents; Kidney Glomerulus; Renal Insufficiency, Chronic; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Uric Acid | 2014 |
Evaluating SGLT2 inhibitors for type 2 diabetes: pharmacokinetic and toxicological considerations.
Topics: Benzhydryl Compounds; Canagliflozin; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Interactions; Glucosides; Hepatic Insufficiency; Humans; Hypoglycemic Agents; Membrane Transport Modulators; Renal Insufficiency; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2014 |
[SGLT-2 inhibition with canagliflozin: a new option for the treatment of type 2 diabetes].
Topics: Blood Glucose; Blood Pressure; Body Weight; Canagliflozin; Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Double-Blind Method; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Kidney; Kidney Concentrating Ability; Randomized Controlled Trials as Topic; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2014 |
Sodium-glucose cotransporter-2 inhibition and the potential for renal protection in diabetic nephropathy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzhydryl Compounds; Canagliflozin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glomerular Filtration Rate; Glucosides; Humans; Hypoglycemic Agents; Kidney Tubules, Proximal; Renal Reabsorption; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Sodium, Dietary; Thiophenes | 2015 |
Sodium glucose cotransporter 2 and the diabetic kidney.
Topics: Animals; Benzhydryl Compounds; Canagliflozin; Diabetes Mellitus; Diabetic Nephropathies; Glucose; Glucosides; Humans; Hypoglycemic Agents; Kidney Tubules, Proximal; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2013 |
Endothelin antagonists for diabetic and non-diabetic chronic kidney disease.
Topics: Animals; Clinical Trials as Topic; Diabetic Nephropathies; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Humans; Isoxazoles; Kidney Failure, Chronic; Pyridines; Pyrimidines; Renal Dialysis; Renal Insufficiency, Chronic; Thiophenes; Treatment Outcome | 2013 |
[Candesartan - a novel AT(1)-angiotensin receptor blocker: peculiarities of pharmacology and experience of use in arterial hypertension].
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetic Nephropathies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2004 |
3 trial(s) available for thiophenes and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Beneficial Effects of Ipragliflozin on the Renal Function and Serum Uric Acid Levels in Japanese Patients with Type 2 Diabetes: A Randomized, 12-week, Open-label, Active-controlled Trial.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Japan; Male; Middle Aged; Renal Insufficiency, Chronic; Risk Factors; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Treatment Outcome; Uric Acid; Young Adult | 2020 |
Efficacy and safety of canagliflozin over 52 weeks in patients with type 2 diabetes mellitus and chronic kidney disease.
Topics: Aged; Blood Glucose; Blood Pressure; Body Weight; Canagliflozin; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Double-Blind Method; Drug Administration Schedule; Female; Glomerular Filtration Rate; Glucosides; Humans; Hypoglycemic Agents; Male; Renal Insufficiency, Chronic; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Treatment Outcome | 2014 |
Effects of the dual peroxisome proliferator-activated receptor-α/γ agonist aleglitazar on renal function in patients with stage 3 chronic kidney disease and type 2 diabetes: a Phase IIb, randomized study.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Dyslipidemias; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kidney; Male; Middle Aged; Oxazoles; Pioglitazone; PPAR alpha; PPAR gamma; Renal Insufficiency, Chronic; Therapeutic Equivalency; Thiazolidinediones; Thiophenes | 2014 |
22 other study(ies) available for thiophenes and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Acute and Direct Effects of Sodium-Glucose Cotransporter 2 Inhibition on Glomerular Filtration Rate in Spontaneously Diabetic Torii Fatty Rats.
Topics: Animals; Blood Glucose; Blood Pressure; Chlorides; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glomerular Filtration Rate; Glucosides; Heart Rate; Male; Rats, Sprague-Dawley; Sodium; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2019 |
Effects of ipragliflozin on the development and progression of kidney disease in patients with type 2 diabetes: An analysis from a multicenter prospective intervention study.
Topics: Aged; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Follow-Up Studies; Glomerular Filtration Rate; Glucosides; Glycated Hemoglobin; Humans; Male; Middle Aged; Prognosis; Prospective Studies; Renal Insufficiency, Chronic; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2020 |
Oltipraz Prevents High Glucose-Induced Oxidative Stress and Apoptosis in RSC96 Cells through the Nrf2/NQO1 Signalling Pathway.
Topics: Animals; Apoptosis; Cell Line; Diabetic Nephropathies; Glucose; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Pyrazines; Rats; Thiones; Thiophenes | 2020 |
Endoplasmic reticulum stress related factor IRE1α regulates TXNIP/NLRP3-mediated pyroptosis in diabetic nephropathy.
Topics: Animals; Cell Cycle Proteins; Cell Line; Diabetic Nephropathies; Disease Models, Animal; Down-Regulation; Endoplasmic Reticulum Stress; Endoribonucleases; Glucose; Kidney Tubules; Male; MicroRNAs; Models, Biological; Multienzyme Complexes; NLR Family, Pyrin Domain-Containing 3 Protein; Protein Serine-Threonine Kinases; Pyroptosis; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; Up-Regulation | 2020 |
Ipragliflozin Ameliorates Diabetic Nephropathy Associated with Perirenal Adipose Expansion in Mice.
Topics: Adipose Tissue; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glucosides; Kidney Glomerulus; Male; Mice; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2021 |
Eprosartan mesylate loaded bilosomes as potential nano-carriers against diabetic nephropathy in streptozotocin-induced diabetic rats.
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Bile Acids and Salts; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Carriers; Drug Delivery Systems; Drug Liberation; Imidazoles; Liposomes; Male; Nanostructures; Particle Size; Rats; Thiophenes | 2018 |
Effects of the SGLT2 inhibitor ipragliflozin on various diabetic symptoms and progression of overt nephropathy in type 2 diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glucose; Glucosides; Hypoglycemic Agents; Kidney; Male; Mice, Inbred ICR; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2018 |
Prevention of progression of diabetic nephropathy by the SGLT2 inhibitor ipragliflozin in uninephrectomized type 2 diabetic mice.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glucosides; Hypertension; Kidney; Losartan; Male; Mice, Inbred C57BL; Nephrectomy; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2018 |
Effects of PPARs/20-HETE on the renal impairment under diabetic conditions.
Topics: Amidines; Anilides; Animals; Cell Line; Cytochrome P-450 CYP4A; Diabetic Nephropathies; Down-Regulation; Epithelial Cells; Gene Expression Regulation; Glucose; Hydroxyeicosatetraenoic Acids; Indoles; Kidney Tubules; Male; Mice; PPAR alpha; PPAR gamma; PPAR-beta; Rats; Sulfones; Thiophenes | 2019 |
Efficacy and safety of canagliflozin in patients with type 2 diabetes and stage 3 nephropathy.
Topics: Aged; Blood Glucose; Blood Pressure; Body Weight; Canagliflozin; Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Glucosides; Glycated Hemoglobin; Humans; Hypertension; Hypoglycemic Agents; Male; Middle Aged; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Severity of Illness Index; Thiophenes; Treatment Outcome | 2014 |
Prevention of diabetic nephropathy by compound 21, selective agonist of angiotensin type 2 receptors, in Zucker diabetic fatty rats.
Topics: Albuminuria; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Evaluation, Preclinical; Fibrosis; Interleukin-10; Kidney; Losartan; Male; Membrane Proteins; Rats, Zucker; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes; Tumor Necrosis Factor-alpha | 2014 |
Ameliorative effect of eprosartan on high-fat diet/streptozotocin-induced early diabetic nephropathy in rats.
Topics: Acrylates; Angiotensin II; Animals; Blood Glucose; Catalase; Cholesterol; Collagen Type IV; Diabetic Nephropathies; Diet, High-Fat; Gene Expression Regulation, Enzymologic; Glutathione; Imidazoles; Kidney; Male; Malondialdehyde; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; RNA, Messenger; Streptozocin; Thiophenes; Transforming Growth Factor beta1; Triglycerides | 2015 |
Blood pressure reduction: an added benefit of sodium-glucose cotransporter 2 inhibitors in patients with type 2 diabetes.
Topics: Benzhydryl Compounds; Blood Pressure; Canagliflozin; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glucosides; Humans; Hypertension; Hypoglycemic Agents; Middle Aged; Randomized Controlled Trials as Topic; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2015 |
AT2R agonist, compound 21, is reno-protective against type 1 diabetic nephropathy.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Immunohistochemistry; Mesangial Cells; Mice; Oxidative Stress; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes | 2015 |
Effect of ipragliflozin, an SGLT2 inhibitor, on progression of diabetic microvascular complications in spontaneously diabetic Torii fatty rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Progression; Glucosides; Hyperglycemia; Hypoglycemic Agents; Male; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2016 |
Fluctuation in Serum Sodium Levels Related to Ipragliflozin Administration in a Patient with Diabetic Nephropathy and Sequela of Traumatic Brain Injury.
Topics: Brain Injuries, Traumatic; Diabetes Mellitus; Diabetic Nephropathies; Fludrocortisone; Glucosides; Humans; Hyponatremia; Insulin; Male; Middle Aged; Sodium; Thiophenes | 2016 |
Duloxetine compliance and its association with healthcare costs among patients with diabetic peripheral neuropathic pain.
Topics: Aged; Aged, 80 and over; Cost-Benefit Analysis; Diabetic Nephropathies; Drug Costs; Duloxetine Hydrochloride; Female; Health Care Costs; Humans; Insurance Claim Review; Male; Medication Adherence; Middle Aged; Retrospective Studies; Thiophenes; United States | 2009 |
Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fingolimod Hydrochloride; Kidney; Lymphocytes; Mice; Mice, Inbred C57BL; Oxadiazoles; Phosphotransferases (Alcohol Group Acceptor); Podocytes; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine; Thiophenes; Tumor Necrosis Factor-alpha | 2011 |
Effects of the dual PPAR-α/γ agonist aleglitazar on glycaemic control and organ protection in the Zucker diabetic fatty rat.
Topics: Animals; Blood Glucose; Cataract; Diabetic Nephropathies; Glucose Tolerance Test; Glycated Hemoglobin; Hypoglycemic Agents; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Oxazoles; PPAR alpha; PPAR gamma; Rats; Rats, Zucker; Thiophenes | 2013 |
Cymbalta and your blood glucose.
Topics: Antidepressive Agents; Blood Glucose; Diabetic Nephropathies; Duloxetine Hydrochloride; Humans; Thiophenes | 2007 |
A platelet aggregation inhibitor--ticlopidine--in diabetic nephropathy: a randomized double blind study.
Topics: Adult; Creatinine; Diabetic Nephropathies; Double-Blind Method; Drug Evaluation; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Platelet Aggregation; Random Allocation; Thiophenes; Ticlopidine | 1984 |
Effect of angiotensin II antagonist eprosartan on hyperglycemia-induced activation of intrarenal renin-angiotensin system in healthy humans.
Topics: Acrylates; Adult; Angiotensin II; Diabetic Nephropathies; Glomerular Filtration Rate; Hemodynamics; Humans; Hyperglycemia; Imidazoles; Kidney; Male; Middle Aged; Renal Circulation; Renin; Renin-Angiotensin System; Thiophenes | 2000 |