Page last updated: 2024-08-18

thiophenes and Depressive Disorder, Major

thiophenes has been researched along with Depressive Disorder, Major in 325 studies

Research

Studies (325)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's134 (41.23)29.6817
2010's182 (56.00)24.3611
2020's9 (2.77)2.80

Authors

AuthorsStudies
Furukawa, Y; Hamza, T; Kasai, K; Obata, S; Oguro, S; Ostinelli, EG1
McIntire, GL; Mulder, HA; Poklis, JL; Wallace, FN1
Boucher, M; de Jong-Laird, A; Katzman, MA; MacKenzie, EM; Therrien, F; Wang, F1
Carpenter, JS; Crouse, JJ; Garland, A; Hickie, IB; Koethe, D; Leweke, FM; McHugh, C; Nichles, A; Rohleder, C; Scott, EM; Song, YJC; Wilson, C; Zmicerevska, N1
Eriksson, H; Meehan, SR; Newcomer, JW; Weiss, C; Zhang, P1
Carroll, KJ; Koch, G; Lee, J; Ouyang, J; Zhang, P1
Antoun Reyad, A; Girgis, E; Mishriky, R1
Baker, RA; Krystal, AD; Lindsten, A; Mittoux, A1
Futamura, T; Hirose, T; Kikuchi, T; Maeda, K; McQuade, RD; Suzuki, M1
Edinoff, AN; Girma, B; Kaye, AD; Kaye, AJ; Kaye, AM; Kaye, JS; Leethy, KN; Maxey, BS; Mychaskiw, G; Odisho, A; Ren, AL; Urits, I; Viswanath, O; Wu, NW1
Briones-Aranda, A; Espinosa-Raya, J; Picazo, O; Suárez-Santiago, JE1
Aftab, A; Gao, K1
Dong, C; Fujita, Y; Futamura, T; Hashimoto, K; Ma, M; Ohgi, Y; Ren, Q; Yang, C1
Higashi, K; Ishigooka, J; Iwashita, S; Liew, EL; Tadori, Y1
Hobart, M; Nelson, JC; Weiller, E; Weiss, C; Zhang, P1
Augustine, C; Carroll, K; Hobart, M; Koch, G; Zhang, P1
Augustine, C; Brewer, C; Hefting, N; Hobart, M; Josiassen, MK; McQuade, RD; Sanchez, R; Skuban, A; Zhang, P1
Aladeen, T; Capote, H; Lee, Y; McIntyre, RS; Rainka, M; Rong, C; Westphal, E1
Burudpakdee, C; Greene, M; Hartry, A; Seetasith, A1
Augustine, C; Brewer, C; Hefting, N; Hobart, M; McQuade, RD; Sanchez, R; Skuban, A; Zhang, P1
Baker, RA; Duffy, RA; Gwin, KK; McQuade, RD; Weiller, E; Weiss, C; Zhang, P1
Hefting, N; Hobart, M; Lepola, U; Zhang, D1
Bauer, M; Hefting, N; Hobart, M; Josiassen, MK; Lindsten, A1
Eriksson, H; Hobart, M; Meehan, SR; Weiss, C; Zhang, P1
Broder, MS; Chang, E; Greene, M; Hartry, A; Yan, T; Yermilov, I1
Brown, ES; Escalante, C; Holmes, T; Ivleva, E; Khaleghi, N; Mason, BL; Nakamura, A; Van Enkevort, E1
Citrome, LL; Manning, JS; McIntosh, D; McIntyre, RS1
Iwata, N; Kishi, T; Matsuda, Y; Mishima, K; Nomura, I; Sakuma, K1
Batur, S; Dobrucali, A; Sadri, S; Sisman, G1
Casas, M; Castells, X; Collazos, F; Eiroa-Orosa, FJ; Qureshi, A; Ramos, M; Ribases, M; Rodriguez, A; Valero, S1
Able, SL; Cui, Z; Faries, DE; Novick, D; Shen, W1
Štuhec, M1
Cheng, Y; Dowsett, SA; Elpers, J; Hoog, SL1
Amore, M; Colicchio, S; Contini, P; de Berardis, D; Escelsior, A; Fornaro, M; Fornaro, P; Martino, M; Rocchi, G1
Berk, M; Deberdt, W; Eriksson, E; Kelin, K; Nelson, JC; Zhang, Q1
Cohen, LS; Connors, S; Freeman, MP; Hirschberg, AM; Joffe, H; Petrillo, LF; Regan, S; Wang, B1
Berk, M; Dodd, S; Kelin, K; Mancini, M; Schacht, A1
Beekman, AT; Bet, PM; de Heer, EW; Dekker, J; Hakkaart-Van Roijen, L; Holwerda, TJ; Kat, F; Ringoir, L; Roth, J; van der Feltz-Cornelis, CM; van Eck van der Sluijs, JF; van Marwijk, HW1
Hida, E; Tango, T2
Amore, M; Colicchio, S; Contini, P; De Berardis, D; Escelsior, A; Fornaro, M; Fornaro, P; Ghio, M; Martino, M; Rocchi, G1
Gaynor, PJ; Lipsius, S; Marangell, LB; Namiki, C; Ohara, F; Robinson, MJ; Sheehan, D; Tanaka, Y1
Chen, Y; Faries, DE; Lipkovich, I; Liu, X; Obenchain, RL; Zagar, A1
Malcolm, SK; Risser, RC; Robinson, MJ; Vollmer, TL1
Arkoub, H; Augendre-Ferrante, B; Evans, D; Pamulapati, S; Perrot, S; Picard, H; Rouillon, F; Valensi, P1
Alam, MY; Chen, Y; Jacobsen, PL; Mahableshwarkar, AR; Serenko, M1
Boulenger, JP; Loft, H; Olsen, CK1
Liu, P; Nelson, JC; Oakes, TM; Raskin, J; Robinson, M; Shoemaker, S1
Lenox-Smith, A; Mancini, M; Perugi, G; Schacht, A; Wade, AG1
Beck, J; Bischof, R; Brand, S; Delini-Stula, A; Eckert, A; Hemmeter, U; Holsboer-Trachsler, E; Mikoteit, T1
Begley, A; Butters, MA; Koenig, AM; Ogbagaber, S; Reynolds, CF; Wahed, AS1
Bahk, WM; Woo, YS1
Chang, HA; Hsu, CC; Kao, YC; Ku, SC; Tzeng, NS1
Atkinson, SD; Bangs, ME; Emslie, GJ; March, JS; Pangallo, BA; Prakash, A; Zhang, Q1
Bangs, ME; Emslie, GJ; March, JS; Pangallo, BA; Prakash, A; Zhang, Q1
Gøtzsche, PC; Hróbjartsson, A; Jørgensen, KJ; Lundh, A; Maund, E; Schroll, J; Tendal, B1
Gøtzsche, PC; Hróbjartsson, A; Lundh, A; Maund, E; Tendal, B1
Doshi, P; dosReis, S; Zito, J1
Chen, M; Han, H; Huang, Z; Wang, J; Zhang, J; Zhang, Y; Zhong, Z1
Lobo, ED; Prakash, A; Quinlan, T1
Gu, S; Guo, J; Luo, H; Qu, W; Tang, Q1
Berggren, L; Gilaberte, I; Lenox-Smith, A; Pérez, V; Quail, D; Romera, I1
Brignone, M; Ereshefsky, L; Francois, C; Lançon, C; Llorca, PM; Rive, B; Salah, S1
Howland, RH1
Adams, TM; Costafreda, SG; Donati, R; Fu, CH; Horton, P; Liu, P; Maglanoc, LA; Marangell, LB; Rasenick, MM; Sankar, A1
Berk, M; Dodd, S; Dueñas, H; Kelin, K; Malhi, GS; Quirk, FH; Reed, VA; Schacht, A; Williams, LJ1
Citrome, L4
Augustine, C; Carson, WH; Eriksson, H; Hobart, M; McQuade, RD; Nyilas, M; Sanchez, R; Skuban, A; Thase, ME; Youakim, JM; Zhang, P1
Carson, WH; Eriksson, H; Hobart, M; McQuade, RD; Nyilas, M; Sanchez, R; Skuban, A; Thase, ME; Youakim, JM; Zhang, P1
McKeage, K1
Stahl, SM1
McIntyre, RS; Weiller, E; Weiss, C; Zhang, P1
Bruijnzeel, D; Tandon, R1
Baker, RA; Ota, A; Perry, P; Sheehan, DV; Tsuneyoshi, K; Weiller, E; Weisler, RH1
Baker, RA; Davidsen, CK; Fava, M; Ménard, F1
Aigbogun, MS; Duffy, R; Hartry, A; Kamat, SA; Legacy, S; Sussman, M; Yu, J1
Baker, RA; Davis, LL; Ota, A; Perry, P; Tsuneyoshi, K; Weiller, E1
Baker, RA; Fava, M; Matsushima, Y; Okame, T; Perry, P; Weiller, E1
Beyer, JL; Weisler, RH1
Baker, RA; Krystal, AD; Meisels, P; Mittoux, A1
Han, C; Jeon, SW; Ko, YH; Masand, PS; Pae, CU; Patkar, AA; Yoon, S1
Dong, C; Futamura, T; Hashimoto, K; Ma, M; Ohgi, Y; Ren, Q; Yang, C; Yao, W; Zhang, JC1
Fava, M; Weiller, E; Weiss, C; Zhang, P1
Gallipani, A; Markovic, M; Maroney, M; Patel, KH1
Gourion, D1
Andersen, HF; Lam, RW; Wade, AG1
Häring, HU; Mörike, K; Müssig, K1
Carvalho, LA; Gorenstein, C; Markus, RP; Moreno, R; Pariante, C1
Deuschle, M; Englisch, S; Knopf, U; Kuwilsky, A; Scharnholz, B; Zink, M1
Gozzi, BF; Menchetti, M; Mercolini, L; Petio, C; Raggi, MA; Saracino, MA1
Brecht, S; Chen, A; Fava, M; Perahia, D; Walker, D; Wiltse, C1
Griffith, JM; Hasley, JP; Severn, DG1
Desaiah, D; Montejo, AL; Perahia, DG; Quail, D; Schatzberg, AF1
Lin, CC1
Chappell, AS; Detke, MJ; Fishbain, DA; Kajdasz, DK; Wernicke, J1
Danchenko, N; Despiegel, N; Fernández, JL; François, C; Hansen, K; Wade, AG1
Ball, S; Brecht, S; Kajdasz, D; Thase, ME1
Deliyannides, DA; McGrath, PJ; Stewart, JW1
Andersen, HF; Kilts, CD; Schlaepfer, TE; Wade, AG1
Guico-Pabia, CJ; Helzner, EC; Nichols, AI; Patroneva, AL; Paul, J; Preskorn, SH1
Adams, DH; Fijal, B; Houston, JP; Perlis, RH; Sutton, VK; Trivedi, MH1
Guàrdia-Olmos, J; Gudayol-Ferré, E; Herrera-Abarca, JE; Herrera-Guzmán, D; Herrera-Guzmán, I; Hinojosa-Calvo, E1
Voznesenskaia, TG1
Detke, MJ; Dunner, DL; Greist, JH; Hollandbeck, MS; Kornstein, SG; Mallinckrodt, CH; Meyers, AL; Whitmyer, VG; Wohlreich, MM1
Volpe, FM1
Gaynor, PJ; Houston, JP; Katz, MM; Meyers, AL; Prakash, A1
Butters, MA; Dew, MA; Driscoll, HC; Lenze, EJ; Miller, MD; Mulsant, BH; Pollock, BG; Reynolds, CF; Sheffrin, M1
Baldessarini, RJ; Del Casale, A; Girardi, P; Innamorati, M; Mancini, M; Mazzarini, L; Pompili, M; Serafini, G; Tatarelli, R1
Alamo, C; Camarasa, X; García-García, P; López-Muñoz, F; Pardo, A; Seguí, J1
Amore, M; Gianni, W; Mancini, M; Rossi, A1
Aström, M; Brecher, M; Cutler, AJ; Feifel, D; Lazarus, A; Montgomery, SA1
Spadone, C1
Cerveri, G; Colasanti, A; De Gaspari, IF; Fiorentini, A; Mauri, MC; Mencacci, C; Papa, P; Valli, A; Volonteri, LS1
Hadikusumo, B; Ng, B1
Detke, MJ; Maina, G; Perahia, DG; Spann, ME; Thase, ME; Walker, DJ; Wang, F1
Bourgeois, JA; Davidson, CM; Harlow, MC1
Andersen, HF; Kornstein, SG; Larsson, S; Li, D; Mao, Y; Papakostas, GI1
Begley, A; Dew, MA; Karp, JF; Miller, MD; Reynolds, CF; Weiner, DK1
Corruble, E; Goldberger, C; Spann, M1
Lai, CH6
Guàrdia-Olmos, J; Gudayol-Ferré, E; Herrera-Abarca, JE; Herrera-Guzmán, D; Herrera-Guzmán, I; Montelongo-Pedraza, P; Padrós Blázquez, F; Peró-Cebollero, M1
Gartlehner, G; Gaynes, BN; Hansen, RA; Thaler, K1
Nelson, JC2
Biehn, TL; Sawrey, DL; Spielmans, GI1
Aikins, D; Kasserman, S; Neumeister, A; Nishimura, C; Vojvoda, D; Walderhaug, E1
Bitter, I; Karamustafalioglu, O; Koponen, H; Mohr, P; Sartorius, N; Seifritz, E; Svestka, J1
Berk, M; Kelin, K; Perahia, D; Raskin, J; Sagman, D; Spann, M; Walker, D1
Despiégel, N; Lam, RW; Lönn, SL1
Norman, TR; Olver, JS1
Gómez-Carbajal, L; Gudayol-Ferré, E; Herrera-Abarca, JE; Herrera-Guzmán, D; Herrera-Guzmán, I; Joan, GO; Peña-Olvira, M; Villuendas-González, E1
Mancini, M; Perna, G; Petralia, A; Rossi, A1
Bradley, L; Choy, E; Clauw, DJ; Marangell, LB; Mease, P; Shoemaker, S; Wang, F; Wohlreich, MM1
Dolder, C; Nelson, M; Stump, A1
Hsu, YY; Lai, CH1
Cardoner, N; Contreras-Rodríguez, O; Deus, J; Harrison, BJ; Hernández-Ribas, R; López-Solà, M; Menchón, JM; Ortiz, H; Pujol, J; Soriano-Mas, C; Vallejo, J1
Danchenko, N; Despiegel, N; Maman, K; Marteau, F; Nordström, G1
Able, SL; Faries, DE; Gelwicks, S; Liu, X1
Becker, T; Grouven, U; Kaiser, T; Kerekes, MF; Koesters, M; Kreis, J; Kromp, M; Schueler, YB; Weinmann, S; Wieseler, B1
Brecht, S; Desaiah, D; Guelfi, JD; Marechal, ES; Podhorna, J; Santini, AM1
Desaiah, D; Detke, MJ; Kennedy, SH; Pangallo, BA; Perahia, DG; Zhang, Q1
Bandelow, B; Wolff-Menzler, C1
Campbell, C; Liu, J; Shi, L; Zhao, Y1
Ansseau, M; Pitchot, W; Scantamburlo, G1
Granger, RE; Hussain, N; Lee, AC; Lee, MS; Li, H; McIntosh, D; Raskin, J; Ruschel, S; Sagman, D1
Detke, MJ; Montejo, AL; Perahia, DG; Spann, ME; Walker, DJ; Wang, F; Yang, CR1
Harnett-Sheehan, K; Prakash, A; Sheehan, DV; Spann, ME; Thompson, HF1
Chang, JP; Su, KP; Wu, CC1
Chang, CH; Chen, SJ; Chen, ST; Hsiao, YL; Shen, TW1
Ameri, AA1
Spingler, A1
Spielmans, GI1
Bär, KJ; Berger, S; Boettger, MK; Boettger, S; Terhaar, J; Weiss, T1
Able, SL; Liu, X; Tepper, PG1
Robinson, RL; Swindle, RW; Ye, W; Zhao, Y1
Arbuckle, M; Harding, KJ; Pincus, HA; Rush, AJ; Trivedi, MH1
Connemann, BJ; Gahr, M; Schönfeldt-Lecuona, CJ; Weydt, P1
Delbello, MP; Nandagopal, JJ; Strawn, JR; Whitsel, R1
Boyce, PM; Hackett, LP; Ilett, KF1
Chiesa, A; De Ronchi, D; Mencacci, C; Nasso, ED; Serretti, A1
Ben-Hamadi, R; Dworak, H; Erder, MH; Ramakrishnan, K; Signorovitch, J; Wu, EQ; Yu, AP1
Liu, X; Mullins, CD; Wang, J1
Fuchs, D; Galfalvy, HC; Grunebaum, MF; Lapidus, M; Mann, JJ; Oquendo, MA; Postolache, TT; Sublette, ME1
Chokka, PR; Granger, RE; Raskin, J; Sagman, D; Sheehan, DV; Walton, RJ1
Heinloth, A; Houston, JP; Kohler, J; Ostbye, KM; Perlis, RH1
Bandini, F; Cestari, L; Colicchio, S; Cordano, C; Escelsior, A; Fornaro, M; Martino, M; Ogliastro, C; Perugi, G; Rocchi, G1
Lai, CH; Wu, YT2
Gaynor, PJ; Gopal, M; Hann, D; Marangell, LB; Martinez, JM; Robinson, MJ; Zheng, W1
Gaynor, PJ; Gopal, M; Marangell, LB; Martinez, JM; Robinson, MJ; Zheng, W1
Bogetto, F; Maina, G; Rigardetto, S; Rosso, G1
Eraslan, D; Ergun, BM; Genc, Y; Odabasioglu, G; Ozturk, O1
Cui, Z; Faries, DE; Liu, X; Novick, D; Zhao, Y1
Liu, J; Shi, L; Zhao, Y1
Dersch, R; Voderholzer, U; Zwernemann, S1
Cui, Z; Faries, DE; Gelwicks, S; Liu, X; Novick, D1
Bochsler, L; Norman, TR; Olver, JS1
Ball, T; Cui, Z; Faries, DE; Johnstone, B; Liu, X; Niu, L1
Edwards, SE; Greist, JH; Katon, W; Kroenke, K; Marangell, LB; Martinez, JM; Meyers, AL; Shoemaker, S; Swindle, R; Thase, ME1
Badr, MG; Brnabic, AJ; Chung, KF; Dossenbach, M; Dueñas, H; Jian, H; Lai, CH; Lee, A; Ruiz, JR; Uy-Ponio, T; Varrey, P1
Brnabic, AJ; Casimiro-Querubin, ML; Dossenbach, M; Dueñas, H; Khaled, M; Lee, A; Montejo, AL; Prakash, S; Raskin, J1
Brecht, S; Croenlein, J; Demyttenaere, K; Desaiah, D; Petit, C1
Gueorguieva, R; Krystal, JH; Mallinckrodt, C1
Baldwin, DS; Dragheim, M; Loft, H1
Ahl, J; Kornstein, SG; Marangell, LB; Myers, AL; Oakes, TM; Prakash, A; Thase, ME1
Dharia, S; Fijal, B; Houston, JP; Perlis, RH1
Bullok, KE; Emslie, GJ; Kratochvil, CJ; Lobo, E; March, JS; Pangallo, BA; Prakash, A; Quinlan, T; Tamura, RN1
Hatzinger, M; Imboden, C1
Deberdt, W; Karamustafalioglu, O; Lipkovich, IA; Marangell, LB; Nelson, JC; Zhang, Q1
Balzarro, B; De Ronchi, D; Pellicciari, A; Porcelli, S; Scaramelli, A; Serretti, A1
Cao, Z; Durden, E; Happich, M; Schacht, A; Shi, N; Torres, A1
George, T; Granger, RE; Hussain, N; Marangell, LB; Raskin, J; Zhao, GW1
Hegerl, U; Hundemer, HP; Linden, M; Mergl, R; Quail, D; Schneider, E; Strauß, M1
Hansen, T; Katona, C; Olsen, CK1
Berrocoso, E; Elorza, J; Mico, JA; Perez-Caballero, L; Torres-Sanchez, S1
Chen, X; Huang, L; Jia, Y; Ling, X; Liu, S; Wang, Y; Xu, G1
Boess, FG; Hegerl, U; Linden, M; Mergl, R; Schacht, A; Schneider, E; Wilhelm, S1
Aris, V; Chen, P; Fijal, B; Heinloth, AN; Houston, JP; Martinez, J; Zou, W1
Alten, R; Bär, KJ; Häuser, W; Petzke, F; Sommer, C; Späth, M; Tölle, T; Uçeyler, N; Winkelmann, A; Winter, E1
Kieser, M; Stucke, K1
Binder, EB; Craighead, WE; Cubells, JF; Dunlop, BW; Goodman, MM; Kelley, ME; Kinkead, B; Kutner, M; Mayberg, HS; Nemeroff, CB; Newport, DJ; Owens, MJ; Pace, TW; Ritchie, JC; Rivera, VA; Westen, D1
Abbar, M; Gilaberte, I; Menchón, JM; Neuhauser, D; Papen, R; Pérez, V; Picard, H; Romera, I; Schacht, A1
Chang, JP; Wu, CC1
Amore, M; Deberdt, W; Demyttenaere, K; Mancini, M; Quail, D; Sagman, D; Sheehan, DV1
Contini, P; Escelsior, A; Fornaro, M; Martino, M; Rocchi, G1
Bech, P; Lindberg, L; Lund, V; Lunde, M; Martiny, K; Refsgaard, E; Sørensen, L; Thougaard, B1
Avanzino, L; Bonuccelli, U; Caltagirone, C; Ceravolo, R; Dell'Agnello, G; Fabbrini, G; Guadagna, M; Mancini, M; Meco, G; Morgante, F; Pierantozzi, M; Rossi, A; Ruggieri, S; Silvestrini, M; Spezia, R; Stocchi, F; Tessitore, A1
Li, RM; Liu, ZW; Wang, C; Zhao, B1
Greist, JH; Katona, C; Liu, P; Oakes, TM; Raskin, J; Robinson, M1
Avena-Woods, C; Hilas, O1
Gottlieb, B; Sacks, Z; Sharma, N; Vaidya, A1
Dhillon, S1
Ahl, J; Fijal, BA; Houston, JP; Kohler, J; Ostbye, K1
Chen, Y; Jacobsen, PL; Mahableshwarkar, AR1
Greenman, D; Kaufman, KR; Madraswala, R; Podolsky, D1
Detke, MJ; Goldstein, DJ; Lu, Y; Mallinckrodt, C; Nemeroff, CB; Schatzberg, AF; Tran, PV1
Ferguson, MB; Goldstein, DJ; Mallinckrodt, CH; Raskin, J1
Leo, RJ1
Demitrack, MA; Detke, MJ; Goldstein, DJ; Lu, Y; Mallinckrodt, C; Wiltse, C1
Preskorn, SH1
Detke, MJ; Mallinckrodt, CH; Raskin, J; Watkin, JG; Wohlreich, MM1
Arnold, LM; Crofford, LJ; Detke, MJ; Goldstein, DJ; Iyengar, S; Lu, Y; Wohlreich, M1
Brannan, SK; Brown, EB; Mallinckrodt, CH; Schatzberg, AF; Watkin, JG; Wohlreich, MM1
Dugan, SE; Fuller, MA1
Greist, J; Mallinckrodt, CH; McNamara, RK; Raskin, J; Rayamajhi, JN1
Kirkpatrick, P; Waitekus, AB1
Bitter, I; Demitrack, MA; Detke, MJ; Mallinckrodt, CH; McNamara, RK; Wiltse, CG1
Albano, D; Zajecka, JM1
Liu, C; Mallinckrodt, CH; Raskin, J; Watkin, JG; Wohlreich, MM1
Detke, MJ; Kennedy, JS; Mallinckrodt, CH; Nelson, JC; Watkin, JG; Wohlreich, MM1
Laustsen, G; Wimett, L1
Cowen, PJ; Gama, J; Ogilvie, AD1
Almási, J; Rihmer, Z1
Gören, JL; Kirwin, JL1
Bymaster, FP; Detke, MJ; Iyengar, S; Knadler, MP; Lee, TC1
Hudson, JI; Kajdasz, DK; Mallinckrodt, CH; Martynov, OV; Watkin, JG; Wohlreich, MM1
Konarski, JZ; McIntyre, RS1
Brannan, SK; Delgado, PL; Detke, MJ; Mallinckrodt, CH; McNamara, RK; Tran, PV; Wang, F; Watkin, JG1
D'Souza, DN; Detke, MJ; Dunner, DL; Kajdasz, DK; Russell, JM1
Detke, MJ; Hirschfeld, RM; Lee, TC; Mallinckrodt, C1
Einarson, TR; van Baardewijk, M; Vis, PM2
Briley, M; Grady, MM; Moret, C; Stahl, SM1
Cobb, C; Crichlow, R1
Bettinger, TL; Crismon, ML; Hunziker, ME; Suehs, BT1
Gahimer, J; Viktrup, L; Wernicke, JF; Wulster-Radcliffe, M; Yalcin, I1
Desaiah, D; Haddad, PM; Kajdasz, DK; Perahia, DG1
Andorn, AC; Mallinckrodt, CH; Prakash, A; Watkin, JG; Wohlreich, MM1
Fava, M; Mallinckrodt, CH; Martinez, JM; Prakash, A; Watkin, JG; Wohlreich, MM1
Arnold, LM; D'Souza, DN; Goldstein, DJ; Iyengar, S; Pritchett, YL; Rosen, A; Wernicke, JF1
Kozian, R1
Burns, AM; Fava, M; Fisher, LB; Homberger, CH; Iosifescu, DV; Kinrys, G; Mischoulon, D; Papakostas, GI; Worthington, JJ1
Bailey, RK; Mallinckrodt, CH; Plewes, JM; Watkin, JG; Wohlreich, MM1
Keltner, NL; Lee, SI1
Balestrieri, M; Detke, MJ; Fava, M; Perahia, D; Raskin, J; Wang, F1
Norman, TR1
Detke, MJ; Mallinckrodt, CH; Perahia, DG; Walker, DJ; Wang, F1
Kajdasz, DK; Perahia, DG; Raskin, J; Tylee, A; Walker, DJ1
Deuschle, M; Knopf, U; Kuwilsky, A; Mase, E; Zink, M1
Das, A; Desarkar, P; Sinha, VK1
Kornstein, SG; Mallinckrodt, CH; Stewart, DE; Watkin, JG; Wohlreich, MM2
Hanretta, AT; Malek-Ahmadi, P1
Carter, WP; Mallinckrodt, CH; Prakash, A; Watkin, JG; Wohlreich, MM1
Eckert, L; Lançon, C1
Cookson, J; Desaiah, D; Gilaberte, I; Kajdasz, DK1
Kajdasz, DK; Perahia, DG; Raskin, J; Royer, MG; Walker, DJ1
Blanco, C; Lewis-Fernández, R; Mallinckrodt, CH; Plewes, JM; Watkin, JG; Wohlreich, MM1
Acharya, N; Baldessarini, RJ; Cavazzoni, PA; D'Souza, DN; Perahia, DG; Polzer, JP; Rosen, AS1
Jimenez-Genchi, A1
Krüger, S; Lindstaedt, M1
Gahimer, J; Ossanna, MJ; Viktrup, L; Wernicke, J; Wulster-Radcliffe, M; Yalcin, I1
Kluge, M; Schüssler, P; Steiger, A1
Meighen, KG1
Ballesteros, J; Callado, LF; Gutiérrez, M1
Bauer, M; Froud, DM; Jain, R; Kajdasz, DK; Perahia, DG; Pritchett, YL; Raskin, J; Russell, JM; Spencer, KA; Thase, ME; Walker, DJ1
Kajdasz, DK; Lledó, A; Raskin, J; Wang, F; Wernicke, J1
Colman, SA; Harrison, GA; Hong, JP; Lee, MS; Lee, P; Liu, CY; Raskin, J; Ruschel, S; Shu, L; Wang, CY; Xu, X1
Aboujaoude, EN; Gamel, NN; Koran, LM1
Detke, MJ; Faries, DE; Mallinckrodt, CH; Meyers, AL; Prakash, A1
Dinkel, JJ; Mohs, RC; Raskin, J; Rotz, BT; Sheikh, J; Siegal, A; Wiltse, CG; Xu, J1
Aaronson, ST; Arnold, LM; Mallinckrodt, CH; Pigott, TA; Prakash, A; Wohlreich, MM1
Florea, I; Gembert, K; Wade, A1
Alexopoulos, GS; Bose, A; Gandhi, C; Gommoll, C; Khan, A; Li, D1
Frampton, JE; Plosker, GL1
Kajdasz, DK; Raskin, J; Xu, JY1
Iosifescu, DV; Raskin, J; Sheridan, M; Wiltse, CG; Wise, TN; Xu, JY1
Cohen, LS; Joffe, H; Koch, JK; Petrillo, LF; Soares, CN; Somley, BL; Viguera, AC1
de Dios, C; Ezquiaga, E1
Kirby, M; Thor, KB; Viktrup, L1
Dunner, DL; Fava, M; Kornstein, S; Munoz, R; O'Reardon, J; Trivedi, M; Wilson, M; Wohlreich, M1
Michel, MC1
Detke, MJ; Mallinckrodt, CH; Prakash, A; Raskin, J; Robinson, MJ; Shelton, RC; Wohlreich, MM1
Clayton, A; Kornstein, S; Mallinckrodt, C; Prakash, A; Wohlreich, M1
Detke, MJ; Gilaberte, I; Hudson, JI; Perahia, DG; Wang, F; Watkin, JG1
Hsiao, MC; Liu, CY1
Hara, C; Ramos, MG; Rocha, FL1
Gandhi, P; Perahia, DG; Peveler, RC; Quail, D; Walker, DJ1
Andorn, AC; Detke, MJ; Mallinckrodt, CH; Raskin, J; Shelton, RC; Watkin, JG; Wohlreich, MM1
Detke, MJ; Ossanna, MJ; Pritchett, YL; Swindle, RW; Thase, ME; Xu, J1
Detke, MJ; Fava, M; Houston, JP; Mallinckrodt, CH; Prakash, A; Swindle, R1
Brecht, S; Courtecuisse, C; Croenlein, J; Debieuvre, C; Demyttenaere, K; Desaiah, D; Petit, C; Raskin, J1
Dunner, DL; Gonzales, JS; Greist, JH; Kornstein, SG; Mallinckrodt, CH; Meyers, AL; Whitmyer, VG; Wohlreich, MM1
Desaiah, D; Dinkel, JJ; Katona, C; Raskin, J; Walker, DJ; Wiltse, CG1
Liskow, BI; Parikh, AR; Tamano, EA; Thatcher, BT1
Huguelet, P; Perroud, N; Relecom, C1
Karakatsanis, NA; Karapoulios, E; Kouzoupis, AV; Masdrakis, VG; Oulis, P; Soldatos, CR1
Eisfeld, BS; Kennedy, SH; Ravindran, LN1
Begley, A; Dew, MA; Karp, JF; Lenze, EJ; Miller, MD; Reynolds, CF; Whyte, EM1
Corruble, E; Desaiah, D; Fava, M; Perahia, DG; Quail, D1
Barzman, DH; Coffey, B; Delgado, SV; Saldaña, SN1
Armstrong, EP; Erder, MH; Malone, DC1
Möller, HJ; Müller, N; Riedel, M; Schennach, R1
Demitrack, MA; Goldstein, DJ; Lu, Y; Mallinckrodt, C1

Reviews

76 review(s) available for thiophenes and Depressive Disorder, Major

ArticleYear
Optimal dose of brexpiprazole for augmentation therapy of antidepressant-refractory depression: A systematic review and dose-effect meta-analysis.
    Psychiatry and clinical neurosciences, 2022, Volume: 76, Issue:9

    Topics: Adolescent; Adult; Antidepressive Agents; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Female; Humans; Male; Quinolones; Randomized Controlled Trials as Topic; Reproducibility of Results; Thiophenes

2022
Efficacy and safety of brexpiprazole in acute management of psychiatric disorders: a meta-analysis of randomized controlled trials.
    International clinical psychopharmacology, 2020, Volume: 35, Issue:3

    Topics: Antipsychotic Agents; Aripiprazole; Depressive Disorder, Major; Humans; Psychiatric Status Rating Scales; Quetiapine Fumarate; Quinolones; Schizophrenia; Thiophenes; Treatment Outcome

2020
Discovery research and development history of the dopamine D
    Neuropsychopharmacology reports, 2021, Volume: 41, Issue:2

    Topics: Aripiprazole; Depressive Disorder, Major; Dopamine; Dopamine Agonists; Humans; Quinolones; Research; Thiophenes; United States

2021
Brexpiprazole for the Treatment of Schizophrenia and Major Depressive Disorder: A Comprehensive Review of Pharmacological Considerations in Clinical Practice.
    Psychopharmacology bulletin, 2021, 03-16, Volume: 51, Issue:2

    Topics: Antipsychotic Agents; Depressive Disorder, Major; Humans; Quinolones; Schizophrenia; Thiophenes

2021
The preclinical discovery and development of brexpiprazole for the treatment of major depressive disorder.
    Expert opinion on drug discovery, 2017, Volume: 12, Issue:10

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Quinolones; Thiophenes

2017
Adjunctive Brexpiprazole and Functioning in Major Depressive Disorder: A Pooled Analysis of Six Randomized Studies Using the Sheehan Disability Scale.
    The international journal of neuropsychopharmacology, 2019, 03-01, Volume: 22, Issue:3

    Topics: Antidepressive Agents; Depressive Disorder, Major; Disability Evaluation; Double-Blind Method; Drug Therapy, Combination; Humans; Prospective Studies; Quinolones; Randomized Controlled Trials as Topic; Serotonin Agents; Single-Blind Method; Thiophenes

2019
Brexpiprazole as Adjunctive Treatment for Major Depressive Disorder Following Treatment Failure With at Least One Antidepressant in the Current Episode: a Systematic Review and Meta-Analysis.
    The international journal of neuropsychopharmacology, 2019, 11-01, Volume: 22, Issue:11

    Topics: Antidepressive Agents; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Humans; Outcome Assessment, Health Care; Quinolones; Randomized Controlled Trials as Topic; Serotonin Agents; Thiophenes

2019
Treatment response for acute depression is not associated with number of previous episodes: lack of evidence for a clinical staging model for major depressive disorder.
    Journal of affective disorders, 2013, Sep-05, Volume: 150, Issue:2

    Topics: Acute Disease; Adult; Antidepressive Agents; Citalopram; Cyclohexanols; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Paroxetine; Recurrence; Thiophenes; Time Factors; Treatment Outcome; Venlafaxine Hydrochloride

2013
Benefits and harms in clinical trials of duloxetine for treatment of major depressive disorder: comparison of clinical study reports, trial registries, and publications.
    BMJ (Clinical research ed.), 2014, Jun-04, Volume: 348

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Clinical Protocols; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Registries; Selective Serotonin Reuptake Inhibitors; Thiophenes

2014
Relative efficacy and tolerability of vortioxetine versus selected antidepressants by indirect comparisons of similar clinical studies.
    Current medical research and opinion, 2014, Volume: 30, Issue:12

    Topics: Acetamides; Adult; Aged; Antidepressive Agents; Benzofurans; Citalopram; Cyclohexanols; Depressive Disorder, Major; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Female; Humans; Hypnotics and Sedatives; Indoles; Male; Middle Aged; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Sulfides; Thiophenes; Venlafaxine Hydrochloride; Vilazodone Hydrochloride; Vortioxetine

2014
Nocebo effects in the treatment of major depression: results from an individual study participant-level meta-analysis of the placebo arm of duloxetine clinical trials.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:6

    Topics: Antidepressive Agents; Controlled Clinical Trials as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Nocebo Effect; Thiophenes; Treatment Outcome

2015
Brexpiprazole for schizophrenia and as adjunct for major depressive disorder: a systematic review of the efficacy and safety profile for this newly approved antipsychotic - what is the number needed to treat, number needed to harm and likelihood to be hel
    International journal of clinical practice, 2015, Volume: 69, Issue:9

    Topics: Antidepressive Agents; Antipsychotic Agents; Chemotherapy, Adjuvant; Clinical Trials as Topic; Depressive Disorder, Major; Dopamine Agonists; Humans; Quinolones; Schizophrenia; Thiophenes

2015
Brexpiprazole: a new dopamine D₂receptor partial agonist for the treatment of schizophrenia and major depressive disorder.
    Drugs of today (Barcelona, Spain : 1998), 2015, Volume: 51, Issue:7

    Topics: Depressive Disorder, Major; Dopamine Agonists; Humans; Quinolones; Receptors, Dopamine D2; Schizophrenia; Thiophenes

2015
Brexpiprazole (Rexulti) for schizophrenia and depression.
    The Medical letter on drugs and therapeutics, 2015, Aug-17, Volume: 57, Issue:1475

    Topics: Animals; Depressive Disorder, Major; Dopamine Agonists; Humans; Quinolones; Randomized Controlled Trials as Topic; Schizophrenia; Serotonin Agents; Thiophenes

2015
Adjunctive Brexpiprazole: A Review in Major Depressive Disorder.
    CNS drugs, 2016, Volume: 30, Issue:2

    Topics: Antidepressive Agents; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Drug Therapy, Combination; Humans; Quinolones; Thiophenes

2016
Spotlight on brexpiprazole and its potential in the treatment of schizophrenia and as adjunctive therapy for the treatment of major depression.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Animals; Depressive Disorder, Major; Humans; Quinolones; Schizophrenia; Thiophenes

2016
Adjunctive Brexpiprazole as a Novel Effective Strategy for Treating Major Depressive Disorder: A Systematic Review and Meta-Analysis.
    Journal of clinical psychopharmacology, 2017, Volume: 37, Issue:1

    Topics: Depressive Disorder, Major; Humans; Quinolones; Serotonin Agents; Thiophenes

2017
Brexpiprazole.
    The Annals of pharmacotherapy, 2017, Volume: 51, Issue:4

    Topics: Antidepressive Agents; Antipsychotic Agents; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Drug Therapy, Combination; Humans; Quinolones; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Schizophrenia; Thiophenes; Weight Gain

2017
[Antidepressants and their onset of action: a major clinical, methodological and pronostical issue].
    L'Encephale, 2008, Volume: 34, Issue:1

    Topics: Affect; Antidepressive Agents; Citalopram; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Mianserin; Mirtazapine; Patient Satisfaction; Personality Inventory; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Suicide Prevention; Thiophenes; Time Factors; Treatment Refusal; Venlafaxine Hydrochloride

2008
Escitalopram and duloxetine in the treatment of major depressive disorder: a pooled analysis of two trials.
    International clinical psychopharmacology, 2008, Volume: 23, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes

2008
The relationship between antidepressant and analgesic responses: findings from six placebo-controlled trials assessing the efficacy of duloxetine in patients with major depressive disorder.
    Current medical research and opinion, 2008, Volume: 24, Issue:11

    Topics: Adult; Analgesia; Analgesics; Antidepressive Agents; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Placebos; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome

2008
Clinical impact of duloxetine treatment on sleep in patients with major depressive disorder.
    International clinical psychopharmacology, 2008, Volume: 23, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sleep; Sleep Wake Disorders; Thiophenes; Treatment Outcome

2008
Effect of desvenlafaxine on the cytochrome P450 2D6 enzyme system.
    Journal of psychiatric practice, 2008, Volume: 14, Issue:6

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanols; Cytochrome P-450 CYP2D6; Depressive Disorder, Major; Desipramine; Desvenlafaxine Succinate; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Health Status; Humans; Paroxetine; Thiophenes

2008
Duloxetine in acute major depression: review of comparisons to placebo and standard antidepressants using dissimilar methods.
    Human psychopharmacology, 2009, Volume: 24, Issue:3

    Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Placebos; Randomized Controlled Trials as Topic; Thiophenes

2009
Duloxetine in the management of elderly patients with major depressive disorder: an analysis of published data.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:5

    Topics: Age Factors; Aged; Animals; Controlled Clinical Trials as Topic; Depressive Disorder, Major; Disease Management; Duloxetine Hydrochloride; Humans; Thiophenes

2009
[Severe forms of depression: the efficacy of escitalopram].
    L'Encephale, 2009, Volume: 35, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Clinical Trials as Topic; Cyclohexanols; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Follow-Up Studies; Humans; Paroxetine; Personality Inventory; Psychometrics; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2009
Psychogenic tremor in a patient with a major depressive episode.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2009, Volume: 62, Issue:6

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Cognitive Behavioral Therapy; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Hospitalization; Humans; Olanzapine; Psychophysiologic Disorders; Thiophenes; Tremor

2009
Escitalopram versus SNRI antidepressants in the acute treatment of major depressive disorder: integrative analysis of four double-blind, randomized clinical trials.
    CNS spectrums, 2009, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Citalopram; Cyclohexanols; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Time Factors; Venlafaxine Hydrochloride; Young Adult

2009
The general and comparative efficacy and safety of duloxetine in major depressive disorder: a systematic review and meta-analysis.
    Drug safety, 2009, Volume: 32, Issue:12

    Topics: Antidepressive Agents; Body Weight; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Nausea; Randomized Controlled Trials as Topic; Serotonin Syndrome; Thiophenes

2009
Escitalopram versus serotonin noradrenaline reuptake inhibitors as second step treatment for patients with major depressive disorder: a pooled analysis.
    International clinical psychopharmacology, 2010, Volume: 25, Issue:4

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Citalopram; Cyclohexanols; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Norepinephrine; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride; Young Adult

2010
Continuation treatment of major depressive disorder: is there a case for duloxetine?
    Drug design, development and therapy, 2010, Feb-18, Volume: 4

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Thiophenes

2010
Use of duloxetine in patients with an anxiety disorder, or with comorbid anxiety and major depressive disorder: a review of the literature.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:7

    Topics: Animals; Antidepressive Agents; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Quality of Life; Thiophenes

2010
Comparative pain and mood effects in patients with comorbid fibromyalgia and major depressive disorder: secondary analyses of four pooled randomized controlled trials of duloxetine.
    Pain, 2011, Volume: 152, Issue:1

    Topics: Adult; Affect; Antidepressive Agents; Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Pain Measurement; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes

2011
Pharmacological and clinical profile of newer antidepressants: implications for the treatment of elderly patients.
    Drugs & aging, 2010, Aug-01, Volume: 27, Issue:8

    Topics: Aged; Antidepressive Agents; Citalopram; Clinical Trials as Topic; Cyclohexanols; Depressive Disorder, Major; Desvenlafaxine Succinate; Drug Interactions; Duloxetine Hydrochloride; Humans; Thiophenes

2010
A systematic review of duloxetine and venlafaxine in major depression, including unpublished data.
    Acta psychiatrica Scandinavica, 2011, Volume: 123, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Resistance; Duloxetine Hydrochloride; Humans; Pharmacological Phenomena; Randomized Controlled Trials as Topic; Remission Induction; Therapeutic Equivalency; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2011
Predictors of remission with placebo using an integrated study database from patients with major depressive disorder.
    Current medical research and opinion, 2012, Volume: 28, Issue:3

    Topics: Adult; Age of Onset; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Models, Theoretical; Placebo Effect; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Regression Analysis; Remission Induction; ROC Curve; Thiophenes; Treatment Outcome

2012
Preclinical discovery of duloxetine for the treatment of depression.
    Expert opinion on drug discovery, 2012, Volume: 7, Issue:8

    Topics: Animals; Antidepressive Agents; Depressive Disorder, Major; Drug Evaluation, Preclinical; Duloxetine Hydrochloride; Humans; Thiophenes

2012
[Drug therapy of fibromyalgia syndrome. Systematic review, meta-analysis and guideline].
    Schmerz (Berlin, Germany), 2012, Volume: 26, Issue:3

    Topics: Amitriptyline; Analgesics; Analgesics, Opioid; Antidepressive Agents; Anxiety Disorders; Combined Modality Therapy; Comorbidity; Cooperative Behavior; Depressive Disorder, Major; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Germany; Humans; Interdisciplinary Communication; Off-Label Use; Patient Care Team; Pregabalin; Somatoform Disorders; Thiophenes

2012
Evaluation of the effect of duloxetine treatment on functioning as measured by the Sheehan disability scale: pooled analysis of data from six randomized, double-blind, placebo-controlled clinical studies.
    International clinical psychopharmacology, 2012, Volume: 27, Issue:6

    Topics: Adult; Aged; Depressive Disorder, Major; Disability Evaluation; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Severity of Illness Index; Statistics as Topic; Thiophenes; Treatment Outcome

2012
Safety and tolerability of duloxetine in elderly patients with major depressive disorder: a pooled analysis of two placebo-controlled studies.
    International clinical psychopharmacology, 2013, Volume: 28, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Least-Squares Analysis; Male; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome

2013
Duloxetine: a review of its use in the management of major depressive disorder in older adults.
    Drugs & aging, 2013, Volume: 30, Issue:1

    Topics: Aged; Animals; Depressive Disorder, Major; Drug Dosage Calculations; Duloxetine Hydrochloride; Humans; Thiophenes

2013
Reboxetine: a norepinephrine selective reuptake pump inhibitor.
    Journal of psychiatric practice, 2004, Volume: 10, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Biological Availability; Clinical Trials as Topic; Cyclopropanes; Depressive Disorder, Major; Drug Approval; Duloxetine Hydrochloride; Humans; Metabolic Clearance Rate; Milnacipran; Morpholines; Reboxetine; Thiazepines; Thiophenes; United States

2004
Duloxetine: a dual reuptake inhibitor.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:12

    Topics: Adrenergic Uptake Inhibitors; Animals; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes

2004
SNRIs in the management of acute major depressive disorder.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 17

    Topics: Acute Disease; Adrenergic Uptake Inhibitors; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Placebos; Randomized Controlled Trials as Topic; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2004
Duloxetine in the treatment of Major Depressive Disorder: a comparison of efficacy in patients with and without melancholic features.
    BMC psychiatry, 2005, Jan-04, Volume: 5

    Topics: Adult; Cohort Studies; Comorbidity; Depressive Disorder; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Multicenter Studies as Topic; Placebos; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes; Treatment Outcome

2005
Efficacy, safety and tolerability of duloxetine 60 mg once daily in major depression.
    Current medical research and opinion, 2005, Volume: 21, Issue:3

    Topics: Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Humans; Placebos; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome

2005
[Review of antidepressants from the TCAs to the third generation drugs].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2004, Volume: 6, Issue:4

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Drug Combinations; Duloxetine Hydrochloride; Humans; Mianserin; Milnacipran; Mirtazapine; Monoamine Oxidase Inhibitors; Morpholines; Piperazines; Pyrimidines; Reboxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Trazodone; Triazoles; Venlafaxine Hydrochloride

2004
Duloxetine: a dual serotonin-norepinephrine reuptake inhibitor for treatment of major depressive disorder.
    Pharmacotherapy, 2005, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Drug Interactions; Duloxetine Hydrochloride; Humans; Middle Aged; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes

2005
The dual transporter inhibitor duloxetine: a review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression.
    Current pharmaceutical design, 2005, Volume: 11, Issue:12

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Microdialysis; Selective Serotonin Reuptake Inhibitors; Thiophenes

2005
Safety and tolerability of duloxetine in the treatment of major depressive disorder: analysis of pooled data from eight placebo-controlled clinical trials.
    Human psychopharmacology, 2005, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Body Weight; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic; Sexual Behavior; Thiophenes

2005
Duloxetine: pharmacoeconomic implications of an antidepressant that alleviates painful physical symptoms.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:5

    Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Economics, Pharmaceutical; Humans; Pain; Pain Measurement; Thiophenes

2005
Is treatment-associated hypomania rare with duloxetine: secondary analysis of controlled trials in non-bipolar depression.
    Journal of affective disorders, 2005, Volume: 87, Issue:1

    Topics: Adult; Bipolar Disorder; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Placebos; Randomized Controlled Trials as Topic; Reproducibility of Results; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2005
Time course of depression-symptom improvement during treatment with duloxetine.
    Depression and anxiety, 2005, Volume: 21, Issue:4

    Topics: Adult; Antidepressive Agents; Back Pain; Depressive Disorder, Major; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Follow-Up Studies; Gastrointestinal Diseases; Guilt; Humans; Hypochondriasis; Male; Pain Measurement; Randomized Controlled Trials as Topic; Remission Induction; Sexual Dysfunctions, Psychological; Shoulder Pain; Sleep Initiation and Maintenance Disorders; Somatoform Disorders; Surveys and Questionnaires; Thiophenes; Time Factors

2005
Cost effectiveness of duloxetine compared with venlafaxine-XR in the treatment of major depressive disorder.
    Current medical research and opinion, 2005, Volume: 21, Issue:8

    Topics: Adolescent; Adult; Cost of Illness; Cost-Benefit Analysis; Cyclohexanols; Decision Trees; Depressive Disorder, Major; Duloxetine Hydrochloride; Economics, Pharmaceutical; Health Care Costs; Humans; Middle Aged; Models, Econometric; Norepinephrine; Ontario; Outpatients; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2005
SNRIs: their pharmacology, clinical efficacy, and tolerability in comparison with other classes of antidepressants.
    CNS spectrums, 2005, Volume: 10, Issue:9

    Topics: Antidepressive Agents; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; In Vitro Techniques; Milnacipran; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride; Vesicular Monoamine Transport Proteins

2005
Duloxetine and venlafaxine-XR in the treatment of major depressive disorder: a meta-analysis of randomized clinical trials.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:11

    Topics: Adult; Cyclohexanols; Data Collection; Delayed-Action Preparations; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Patient Dropouts; Randomized Controlled Trials as Topic; Review Literature as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2005
Duloxetine hydrochloride: a new dual-acting medication for the treatment of major depressive disorder.
    Clinical therapeutics, 2005, Volume: 27, Issue:8

    Topics: Adult; Aged; Antidepressive Agents; Biological Availability; Depressive Disorder, Major; Drug Interactions; Duloxetine Hydrochloride; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Multicenter Studies as Topic; Nausea; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes

2005
Safety and adverse event profile of duloxetine.
    Expert opinion on drug safety, 2005, Volume: 4, Issue:6

    Topics: Cytochrome P-450 Enzyme System; Depressive Disorder, Major; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Half-Life; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress

2005
Symptoms following abrupt discontinuation of duloxetine treatment in patients with major depressive disorder.
    Journal of affective disorders, 2005, Volume: 89, Issue:1-3

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Long-Term Care; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Thiophenes

2005
Duloxetine for the treatment of major depressive disorder: a closer look at efficacy and safety data across the approved dose range.
    Journal of psychiatric research, 2006, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2006
Duloxetine in the treatment of major depressive disorder: comparisons of safety and efficacy.
    Journal of the National Medical Association, 2006, Volume: 98, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Black or African American; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Treatment Outcome; White People

2006
Prospects for the treatment of depression.
    The Australian and New Zealand journal of psychiatry, 2006, Volume: 40, Issue:5

    Topics: Acetamides; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Hypnotics and Sedatives; Nerve Growth Factors; Selective Serotonin Reuptake Inhibitors; Substance P; Thiophenes; Vasopressins

2006
Duloxetine in the treatment of major depressive disorder: comparisons of safety and tolerability in male and female patients.
    Journal of affective disorders, 2006, Volume: 94, Issue:1-3

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Meta-Analysis as Topic; Middle Aged; Multicenter Studies as Topic; Patient Dropouts; Randomized Controlled Trials as Topic; Sex Factors; Thiophenes

2006
Duloxetine efficacy for major depressive disorder in male vs. female patients: data from 7 randomized, double-blind, placebo-controlled trials.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Health Status; Humans; Male; Middle Aged; Multicenter Studies as Topic; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Quality of Life; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Sex Factors; Surveys and Questionnaires; Thiophenes; Treatment Outcome

2006
Duloxetine compared with fluoxetine and venlafaxine: use of meta-regression analysis for indirect comparisons.
    BMC psychiatry, 2006, Jul-24, Volume: 6

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Fluoxetine; Humans; Randomized Controlled Trials as Topic; Regression Analysis; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2006
Duloxetine in the treatment of major depressive disorder: comparisons of safety and efficacy in U.S. Hispanic and majority Caucasian patients.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:9

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Hispanic or Latino; Humans; Multicenter Studies as Topic; Patient Dropouts; Placebos; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes; Treatment Outcome; White People

2006
Duloxetine: meta-analyses of suicidal behaviors and ideation in clinical trials for major depressive disorder.
    Journal of clinical psychopharmacology, 2006, Volume: 26, Issue:6

    Topics: Adult; Antidepressive Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Incidence; Male; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Suicide; Thinking; Thiophenes; Time Factors

2006
An independent meta-analysis using summary data for clinical response, remission, and discontinuation for any reason from the 6 pivotal phase III randomized clinical trials of duloxetine in major depressive disorder.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Paroxetine; Randomized Controlled Trials as Topic; Remission Induction; Thiophenes; Treatment Outcome; Withholding Treatment

2007
An evaluation of the cardiovascular safety profile of duloxetine: findings from 42 placebo-controlled studies.
    Drug safety, 2007, Volume: 30, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Anxiety Disorders; Cardiovascular Diseases; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Placebos; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence

2007
Duloxetine: a review of its use in the treatment of major depressive disorder.
    CNS drugs, 2007, Volume: 21, Issue:7

    Topics: Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Thiophenes

2007
Serotonin and noradrenaline involvement in urinary incontinence, depression and pain: scientific basis for overlapping clinical efficacy from a single drug, duloxetine.
    International journal of clinical practice, 2007, Volume: 61, Issue:8

    Topics: Antidepressive Agents; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Humans; Male; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress

2007
Patterns of depressive symptom response in duloxetine-treated outpatients with mild, moderate or more severe depression.
    International journal of clinical practice, 2007, Volume: 61, Issue:8

    Topics: Adult; Aged; Antidepressive Agents; Cohort Studies; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes; Treatment Outcome

2007
Evidence for the efficacy of duloxetine in treating mild, moderate, and severe depression.
    International clinical psychopharmacology, 2007, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index; Thiophenes; Treatment Outcome

2007
Efficacy of duloxetine and selective serotonin reuptake inhibitors: comparisons as assessed by remission rates in patients with major depressive disorder.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:6

    Topics: Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Fluoxetine; Humans; Paroxetine; Placebos; Randomized Controlled Trials as Topic; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2007
Duloxetine in the treatment of major psychiatric and neuropathic disorders.
    Expert review of neurotherapeutics, 2008, Volume: 8, Issue:4

    Topics: Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Peripheral Nervous System Diseases; Practice Patterns, Physicians'; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress

2008
Compelling or irrelevant? Using number needed to treat can help decide.
    Acta psychiatrica Scandinavica, 2008, Volume: 117, Issue:6

    Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Data Interpretation, Statistical; Depressive Disorder, Major; Dibenzothiazepines; Duloxetine Hydrochloride; Evidence-Based Medicine; Humans; Outcome Assessment, Health Care; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Schizophrenia; Secondary Prevention; Thiophenes; Treatment Outcome

2008

Trials

110 trial(s) available for thiophenes and Depressive Disorder, Major

ArticleYear
Efficacy of adjunctive brexpiprazole on symptom clusters of major depressive disorder: A post hoc analysis of four clinical studies.
    Journal of affective disorders, 2022, 11-01, Volume: 316

    Topics: Adult; Anhedonia; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Fatigue; Humans; Quinolones; Syndrome; Thiophenes; Treatment Outcome

2022
Changes in Metabolic Parameters and Body Weight in Patients With Major Depressive Disorder Treated With Adjunctive Brexpiprazole: Pooled Analysis of Phase 3 Clinical Studies.
    The Journal of clinical psychiatry, 2019, 10-01, Volume: 80, Issue:6

    Topics: Adult; Antidepressive Agents; Blood Glucose; Body Weight; Cholesterol; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Long-Term Care; Male; Middle Aged; Quinolones; Thiophenes; Triglycerides

2019
Pharmacokinetics and Safety of Brexpiprazole Following Multiple-Dose Administration to Japanese Patients With Schizophrenia.
    Journal of clinical pharmacology, 2018, Volume: 58, Issue:1

    Topics: Antipsychotic Agents; Area Under Curve; Asian People; Cytochrome P-450 CYP2D6; Depressive Disorder, Major; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Quinolones; Schizophrenia; Thiophenes

2018
Efficacy of adjunctive brexpiprazole on the core symptoms of major depressive disorder: A post hoc analysis of two pooled clinical studies.
    Journal of affective disorders, 2018, Volume: 227

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinolones; Serotonin Agents; Thiophenes; Treatment Outcome

2018
A case study in identifying targeted patients population in major depressive disorder by enhanced enrichment design.
    Pharmaceutical statistics, 2018, Volume: 17, Issue:2

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Delivery Systems; Humans; Patient Selection; Quinolones; Serotonin Agents; Thiophenes; Treatment Outcome

2018
Efficacy and safety of flexibly dosed brexpiprazole for the adjunctive treatment of major depressive disorder: a randomized, active-referenced, placebo-controlled study.
    Current medical research and opinion, 2018, Volume: 34, Issue:4

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Headache; Humans; Male; Middle Aged; Prospective Studies; Psychomotor Agitation; Quetiapine Fumarate; Quinolones; Thiophenes; Treatment Outcome

2018
A Randomized, Placebo-Controlled Study of the Efficacy and Safety of Fixed-Dose Brexpiprazole 2 mg/d as Adjunctive Treatment of Adults With Major Depressive Disorder.
    The Journal of clinical psychiatry, 2018, 05-22, Volume: 79, Issue:4

    Topics: Adult; Antidepressive Agents; Anxiety; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Psychiatric Status Rating Scales; Quinolones; Thiophenes; Treatment Outcome; Young Adult

2018
A randomised, placebo-controlled 24-week study evaluating adjunctive brexpiprazole in patients with major depressive disorder.
    Acta neuropsychiatrica, 2019, Volume: 31, Issue:1

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Prospective Studies; Quinolones; Serotonin Agents; Thiophenes; Young Adult

2019
NGF serum levels variations in major depressed patients receiving duloxetine.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:9

    Topics: Adaptation, Psychological; Adult; Biomarkers; Depressive Disorder, Major; Drug Resistance; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Nerve Growth Factor; Neuronal Plasticity; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Stress, Psychological; Sympathomimetics; Thiophenes; Time Factors; Treatment Outcome

2013
Baseline patient characteristics associated with placebo remission and their impact on remission with duloxetine and selected SSRI antidepressants.
    Current medical research and opinion, 2013, Volume: 29, Issue:7

    Topics: Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Placebo Effect; Placebos; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2013
Duloxetine for major depressive disorder and daytime and nighttime hot flashes associated with the menopausal transition.
    Maturitas, 2013, Volume: 75, Issue:2

    Topics: Antidepressive Agents; Anxiety; Anxiety Disorders; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hot Flashes; Humans; Menopause; Middle Aged; Patient Selection; Severity of Illness Index; Thiophenes

2013
Effectiveness and cost-effectiveness of transmural collaborative care with consultation letter (TCCCL) and duloxetine for major depressive disorder (MDD) and (sub)chronic pain in collaboration with primary care: design of a randomized placebo-controlled m
    BMC psychiatry, 2013, May-24, Volume: 13

    Topics: Adaptation, Psychological; Antidepressive Agents; Chronic Pain; Cost-Benefit Analysis; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Patient Care Team; Primary Health Care; Quality of Life; Referral and Consultation; Research Design; Self Care; Thiophenes

2013
Relationship between major depressive disorder and associated painful physical symptoms: analysis of data from two pooled placebo-controlled, randomized studies of duloxetine.
    International clinical psychopharmacology, 2013, Volume: 28, Issue:6

    Topics: Adult; Analgesics; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Statistics as Topic; Thiophenes

2013
A randomized, double-blind, placebo-controlled trial of duloxetine for the treatment of pain in patients with multiple sclerosis.
    Pain practice : the official journal of World Institute of Pain, 2014, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Analgesics; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Pain; Thiophenes; Treatment Outcome

2014
Prescribing patterns of duloxetine in France: a prescription assessment study in real-world conditions.
    International journal of clinical pharmacology and therapeutics, 2014, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Anxiety Disorders; Contraindications; Depressive Disorder, Major; Drug Utilization; Duloxetine Hydrochloride; Female; France; Humans; Male; Middle Aged; Thiophenes

2014
Safety, tolerability, and efficacy of vortioxetine (Lu AA21004) in major depressive disorder: results of an open-label, flexible-dose, 52-week extension study.
    International clinical psychopharmacology, 2014, Volume: 29, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety; Depression; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Sexual Dysfunction, Physiological; Suicidal Ideation; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine; Weight Gain; Young Adult

2014
Efficacy and safety of vortioxetine (Lu AA21004), 15 and 20 mg/day: a randomized, double-blind, placebo-controlled, duloxetine-referenced study in the acute treatment of adult patients with major depressive disorder.
    International clinical psychopharmacology, 2014, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Headache; Humans; Internationality; Male; Middle Aged; Nausea; Piperazines; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine; Young Adult

2014
Acute and long-term treatment of late-life major depressive disorder: duloxetine versus placebo.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2014, Volume: 22, Issue:1

    Topics: Age of Onset; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Psychiatric Status Rating Scales; Thiophenes

2014
High baseline BDNF serum levels and early psychopathological improvement are predictive of treatment outcome in major depression.
    Psychopharmacology, 2014, Volume: 231, Issue:15

    Topics: Adult; Antidepressive Agents; Blood Chemical Analysis; Brain-Derived Neurotrophic Factor; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Prognosis; Prospective Studies; Psychiatric Status Rating Scales; Switzerland; Thiophenes; Time Factors; Treatment Outcome

2014
A double-blind efficacy and safety study of duloxetine flexible dosing in children and adolescents with major depressive disorder.
    Journal of child and adolescent psychopharmacology, 2014, Volume: 24, Issue:4

    Topics: Adolescent; Antidepressive Agents; Child; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Suicidal Ideation; Suicide; Thiophenes; Treatment Outcome

2014
A double-blind efficacy and safety study of duloxetine fixed doses in children and adolescents with major depressive disorder.
    Journal of child and adolescent psychopharmacology, 2014, Volume: 24, Issue:4

    Topics: Adolescent; Antidepressive Agents; Child; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Suicidal Ideation; Suicide; Thiophenes; Treatment Outcome

2014
Effects of olanzapine-fluoxetine combination treatment of major depressive disorders on the quality of life during acute treatment period.
    Cell biochemistry and biophysics, 2014, Volume: 70, Issue:3

    Topics: Adult; Benzodiazepines; Depressive Disorder, Major; Drug Administration Schedule; Drug Combinations; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Quality of Life; Sleep Wake Disorders; Somatoform Disorders; Thiophenes

2014
Efficacy and safety of adjunctive brexpiprazole 2 mg in major depressive disorder: a phase 3, randomized, placebo-controlled study in patients with inadequate response to antidepressants.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:9

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinolones; Thiophenes; Treatment Outcome; Young Adult

2015
Adjunctive brexpiprazole 1 and 3 mg for patients with major depressive disorder following inadequate response to antidepressants: a phase 3, randomized, double-blind study.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:9

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinolones; Thiophenes; Treatment Outcome; Young Adult

2015
Brexpiprazole as adjunctive treatment of major depressive disorder with anxious distress: Results from a post-hoc analysis of two randomised controlled trials.
    Journal of affective disorders, 2016, Sep-01, Volume: 201

    Topics: Adult; Antidepressive Agents; Anxiety Disorders; Depression; Depressive Disorder, Major; Dopamine Agonists; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Psychomotor Agitation; Quinolones; Serotonin Agents; Thiophenes; Treatment Outcome

2016
Brexpiprazole as an adjunctive treatment in young adults with major depressive disorder who are in a school or work environment.
    Journal of affective disorders, 2016, Nov-01, Volume: 204

    Topics: Adolescent; Adult; Antidepressive Agents; Depressive Disorder, Major; Drug Administration Schedule; Drug Therapy, Combination; Employment; Female; Follow-Up Studies; Humans; Male; Psychiatric Status Rating Scales; Quinolones; Students; Thiophenes; Treatment Outcome; Young Adult

2016
Adjunctive Brexpiprazole in Patients With Major Depressive Disorder and Irritability: An Exploratory Study.
    The Journal of clinical psychiatry, 2016, Volume: 77, Issue:12

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Irritable Mood; Male; Middle Aged; Outcome Assessment, Health Care; Quinolones; Serotonin Agents; Thiophenes

2016
Adjunctive brexpiprazole in patients with major depressive disorder and anxiety symptoms: an exploratory study.
    Brain and behavior, 2016, Volume: 6, Issue:10

    Topics: Anxiety; Depressive Disorder, Major; Dopamine Agonists; Drug Therapy, Combination; Female; Humans; Least-Squares Analysis; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotropic Drugs; Quinolones; Serotonin Agents; Thiophenes; Treatment Outcome

2016
Switching from Inadequate Adjunctive or Combination Treatment Options to Brexpiprazole Adjunctive to Antidepressant: An Open-Label Study on the Effects on Depressive Symptoms and Cognitive and Physical Functioning.
    The international journal of neuropsychopharmacology, 2017, 01-01, Volume: 20, Issue:1

    Topics: Antidepressive Agents; Aripiprazole; Bupropion; Central Nervous System Stimulants; Cognition; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Female; Humans; Impulsive Behavior; Male; Middle Aged; Psychiatric Status Rating Scales; Quetiapine Fumarate; Quinolones; Sleep; Thiophenes; Treatment Outcome

2017
Effects of Adjunctive Brexpiprazole on Sleep Disturbances in Patients With Major Depressive Disorder: An Open-Label, Flexible-Dose, Exploratory Study.
    The primary care companion for CNS disorders, 2016, Sep-08, Volume: 18, Issue:5

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dopamine Agonists; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinolones; Serotonin Agents; Sleep Wake Disorders; Thiophenes; Treatment Outcome

2016
Effect of antidepressants on melatonin metabolite in depressed patients.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Hypericum; Male; Melatonin; Middle Aged; Plant Extracts; Severity of Illness Index; Thiophenes; Treatment Outcome

2009
Duloxetine for major depressive episodes in the course of psychotic disorders: an observational clinical trial.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:8

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Prospective Studies; Thiophenes

2009
Predictors of relapse in a study of duloxetine treatment in patients with major depressive disorder.
    Journal of affective disorders, 2009, Volume: 113, Issue:3

    Topics: Acute Disease; Adult; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Predictive Value of Tests; Prevalence; Prospective Studies; Recurrence; Severity of Illness Index; Thiophenes

2009
Switching to duloxetine in selective serotonin reuptake inhibitor non- and partial-responders: effects on painful physical symptoms of depression.
    Journal of psychiatric research, 2009, Volume: 43, Issue:5

    Topics: Activities of Daily Living; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Europe; Female; Health Surveys; Humans; Male; Middle Aged; Pain; Pain Measurement; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Surveys and Questionnaires; Thiophenes; Time Factors; Treatment Outcome

2009
Escitalopram and duloxetine in major depressive disorder: a pharmacoeconomic comparison using UK cost data.
    PharmacoEconomics, 2008, Volume: 26, Issue:11

    Topics: Absenteeism; Adolescent; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Cost-Benefit Analysis; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multivariate Analysis; Severity of Illness Index; Sick Leave; Surveys and Questionnaires; Thiophenes; United Kingdom; Young Adult

2008
Is duloxetine effective treatment for depression with atypical features?
    International clinical psychopharmacology, 2008, Volume: 23, Issue:6

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes; Time Factors; Treatment Outcome; Young Adult

2008
Clinical milestones predict symptom remission over 6-month and choice of treatment of patients with major depressive disorder (MDD).
    Journal of psychiatric research, 2009, Volume: 43, Issue:5

    Topics: Adult; Analysis of Variance; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Paroxetine; Patient Compliance; Predictive Value of Tests; Psychiatric Status Rating Scales; Remission Induction; Thiophenes; Treatment Outcome

2009
Variation in catechol-O-methyltransferase is associated with duloxetine response in a clinical trial for major depressive disorder.
    Biological psychiatry, 2009, May-01, Volume: 65, Issue:9

    Topics: Adult; Catechol O-Methyltransferase; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Genome-Wide Association Study; Genotype; Humans; Male; Polymorphism, Single Nucleotide; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2009
Effects of selective serotonin reuptake and dual serotonergic-noradrenergic reuptake treatments on memory and mental processing speed in patients with major depressive disorder.
    Journal of psychiatric research, 2009, Volume: 43, Issue:9

    Topics: Adult; Analysis of Variance; Antidepressive Agents; Citalopram; Cognition; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Memory; Neuropsychological Tests; Neurotransmitter Uptake Inhibitors; Psychiatric Status Rating Scales; Psychomotor Performance; Reaction Time; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thinking; Thiophenes

2009
A randomized, double-blind study of increasing or maintaining duloxetine dose in patients without remission of major depressive disorder after initial duloxetine therapy.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:9

    Topics: Adolescent; Adult; Antidepressive Agents; Cohort Studies; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Personality Inventory; Prospective Studies; Psychometrics; Retreatment; Thiophenes; Treatment Outcome; Young Adult

2008
An 8-week, open-label trial of duloxetine for comorbid major depressive disorder and chronic headache.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:9

    Topics: Adolescent; Adult; Antidepressive Agents; Brazil; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Headache Disorders; Humans; Male; Middle Aged; Pain Measurement; Personality Inventory; Prognosis; Quality of Life; Thiophenes

2008
Early symptom change prediction of remission in depression treatment.
    Psychopharmacology bulletin, 2009, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Predictive Value of Tests; Psychiatric Status Rating Scales; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome; Young Adult

2009
Pilot study of augmentation with aripiprazole for incomplete response in late-life depression: getting to remission.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:2

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Citalopram; Cyclohexanols; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Therapy, Combination; Duloxetine Hydrochloride; Feasibility Studies; Female; Humans; Male; Personality Inventory; Pilot Projects; Piperazines; Quinolones; Thiophenes; Venlafaxine Hydrochloride

2009
Effects of adjunctive reboxetine in patients with duloxetine-resistant depression: a 12-week prospective study.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:8

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Morpholines; Psychiatric Status Rating Scales; Reboxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome; Young Adult

2010
Extended release quetiapine fumarate monotherapy in major depressive disorder: a placebo- and duloxetine-controlled study.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:4

    Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Depressive Disorder, Major; Dibenzothiazepines; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Quetiapine Fumarate; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes

2009
Duloxetine in the prevention of depressive recurrences: a randomized, double-blind, placebo-controlled trial.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:5

    Topics: Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Prevalence; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Sex Distribution; Thiophenes

2009
Effects of duloxetine in treatment-refractory men with posttraumatic stress disorder.
    Pharmacopsychiatry, 2010, Volume: 43, Issue:2

    Topics: Combat Disorders; Comorbidity; Depressive Disorder, Major; Dreams; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Psychiatric Status Rating Scales; Stress Disorders, Post-Traumatic; Thiophenes; Time Factors; Treatment Outcome; Veterans; Warfare

2010
Duloxetine 60 mg/day for the prevention of depressive recurrences: post hoc analyses from a recurrence prevention study.
    International journal of clinical practice, 2010, Volume: 64, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Secondary Prevention; Thiophenes; Treatment Outcome; Young Adult

2010
Efficacy and safety of duloxetine 60 mg and 120 mg daily in patients hospitalized for severe depression: a double-blind randomized trial.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:8

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Hospitalization; Humans; Male; Middle Aged; Personality Inventory; Psychometrics; Suicidal Ideation; Thiophenes

2011
Attributes of response in depressed patients switched to treatment with duloxetine.
    International journal of clinical practice, 2011, Volume: 65, Issue:1

    Topics: Adult; Affective Symptoms; Antidepressive Agents; Chronic Pain; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2011
Sexual function during long-term duloxetine treatment in patients with recurrent major depressive disorder.
    The journal of sexual medicine, 2011, Volume: 8, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Male; Psychiatric Status Rating Scales; Sexual Behavior; Sexual Dysfunction, Physiological; Surveys and Questionnaires; Thiophenes

2011
Assessing remission in major depressive disorder and generalized anxiety disorder clinical trials with the discan metric of the Sheehan disability scale.
    International clinical psychopharmacology, 2011, Volume: 26, Issue:2

    Topics: Antidepressive Agents; Anxiety Disorders; Comorbidity; Depression; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Outpatients; Placebos; Psychiatric Status Rating Scales; Psychometrics; Thiophenes; Time Factors; Treatment Outcome

2011
Pseudohypoalgesia on the skin: a novel view on the paradox of pain perception in depression.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:1

    Topics: Adult; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hot Temperature; Humans; Male; Middle Aged; Pain; Pain Measurement; Pain Perception; Pain Threshold; Skin Physiological Phenomena; Thiophenes

2011
Clinical and demographic predictors of improvement during duloxetine treatment in patients with major depression: an open-label study.
    Clinical drug investigation, 2011, Volume: 31, Issue:6

    Topics: Adult; Antidepressive Agents; Anxiety; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Treatment Outcome

2011
Remission of major depressive disorder without adverse events: a comparison of escitalopram versus serotonin norepinephrine reuptake inhibitors.
    Current medical research and opinion, 2011, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Citalopram; Cyclohexanols; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Norepinephrine; Remission Induction; Serotonin; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride; Young Adult

2011
Clinical and functional outcomes in patients with major depressive disorder and painful physical symptoms switched to treatment with duloxetine.
    Human psychopharmacology, 2011, Volume: 26, Issue:3

    Topics: Adult; Depressive Disorder, Major; Drug Substitution; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2011
Duloxetine's modest short-term influences in subcortical structures of first episode drug-naïve patients with major depressive disorder and panic disorder.
    Psychiatry research, 2011, Nov-30, Volume: 194, Issue:2

    Topics: Adult; Antidepressive Agents; Brain; Brain Mapping; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Middle Aged; Panic Disorder; Psychiatric Status Rating Scales; Statistics as Topic; Thiophenes

2011
Duloxetine versus placebo in the treatment of major depressive disorder and associated painful physical symptoms: a replication study.
    Current medical research and opinion, 2011, Volume: 27, Issue:10

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Pain; Puerto Rico; Remission Induction; Thiophenes; Time Factors; United States

2011
A randomized placebo-controlled trial of duloxetine in patients with major depressive disorder and associated painful physical symptoms.
    Current medical research and opinion, 2011, Volume: 27, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Remission Induction; Thiophenes; Time Factors

2011
A randomized, single-blind, comparison of duloxetine with bupropion in the treatment of SSRI-resistant major depression.
    Journal of affective disorders, 2012, Volume: 136, Issue:1-2

    Topics: Adult; Antidepressive Agents; Bupropion; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Single-Blind Method; Thiophenes

2012
A pragmatic 12-week, randomized trial of duloxetine versus generic selective serotonin-reuptake inhibitors in the treatment of adult outpatients in a moderate-to-severe depressive episode.
    International clinical psychopharmacology, 2012, Volume: 27, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Depressive Disorder, Major; Disability Evaluation; Drugs, Generic; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Outpatients; Prospective Studies; Psychiatric Status Rating Scales; Remission Induction; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Time Factors; Treatment Outcome; United States

2012
Trajectories of depression severity in clinical trials of duloxetine: insights into antidepressant and placebo responses.
    Archives of general psychiatry, 2011, Volume: 68, Issue:12

    Topics: Adult; Antidepressive Agents; Data Interpretation, Statistical; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Linear Models; Male; Patient Dropouts; Placebo Effect; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome

2011
A randomised, double-blind, placebo controlled, duloxetine-referenced, fixed-dose study of three dosages of Lu AA21004 in acute treatment of major depressive disorder (MDD).
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2012, Volume: 22, Issue:7

    Topics: Aged; Analysis of Variance; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Logistic Models; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Reference Values; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine

2012
Assessment of depressive symptoms and functional outcomes in patients with major depressive disorder treated with duloxetine versus placebo: primary outcomes from two trials conducted under the same protocol.
    Human psychopharmacology, 2012, Volume: 27, Issue:1

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Models, Statistical; Psychiatric Status Rating Scales; Recovery of Function; Thiophenes; Treatment Outcome

2012
An open-label safety and pharmacokinetics study of duloxetine in pediatric patients with major depression.
    Journal of child and adolescent psychopharmacology, 2012, Volume: 22, Issue:1

    Topics: Adolescent; Antidepressive Agents; Blood Pressure; Child; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Psychiatric Status Rating Scales; Severity of Illness Index; Suicidal Ideation; Thiophenes; Treatment Outcome

2012
Apathy in currently nondepressed patients treated with a SSRI for a major depressive episode: outcomes following randomized switch to either duloxetine or escitalopram.
    Journal of psychiatric research, 2012, Volume: 46, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Apathy; Citalopram; Cross-Sectional Studies; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Young Adult

2012
A randomized, double-blind, placebo-controlled, duloxetine-referenced, fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with major depressive disorder.
    International clinical psychopharmacology, 2012, Volume: 27, Issue:4

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Cognition Disorders; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Piperazines; Placebos; Psychiatric Status Rating Scales; Sulfides; Thiophenes; Vortioxetine

2012
Hippocampal N-acetylaspartate and morning cortisol levels in drug-naive, first-episode patients with major depressive disorder: effects of treatment.
    Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:11

    Topics: Adolescent; Adult; Antidepressive Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hippocampus; Humans; Hydrocortisone; Magnetic Resonance Spectroscopy; Male; Middle Aged; Thiophenes; Young Adult

2012
Evaluation of genetic models for response in a randomized clinical trial of duloxetine in major depressive disorder.
    Psychiatry research, 2012, Nov-30, Volume: 200, Issue:1

    Topics: Adult; Antidepressive Agents; Catechol O-Methyltransferase; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Models, Genetic; Norepinephrine Plasma Membrane Transport Proteins; Polymorphism, Single Nucleotide; Receptor, Serotonin, 5-HT1A; Surveys and Questionnaires; Thiophenes; Treatment Outcome

2012
Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial.
    Trials, 2012, Jul-09, Volume: 13

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Biomarkers; Brain; Citalopram; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Genetic Testing; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Personality; Predictive Value of Tests; Remission Induction; Research Design; Thiophenes; Treatment Outcome; Young Adult

2012
Early vs. conventional switching of antidepressants in patients with MDD and moderate to severe pain: a double-blind randomized study.
    Journal of affective disorders, 2012, Dec-20, Volume: 143, Issue:1-3

    Topics: Activities of Daily Living; Adult; Aged; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Double-Blind Method; Drug Substitution; Duloxetine Hydrochloride; Female; Humans; Induction Chemotherapy; Male; Middle Aged; Pain; Pain Measurement; Thiophenes; Treatment Outcome; Young Adult

2012
A 9-week randomized trial comparing a chronotherapeutic intervention (wake and light therapy) to exercise in major depressive disorder patients treated with duloxetine.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:9

    Topics: Adult; Aged; Antidepressive Agents; Combined Modality Therapy; Denmark; Depressive Disorder, Major; Duloxetine Hydrochloride; Exercise; Female; Humans; Logistic Models; Male; Middle Aged; Phototherapy; Prospective Studies; Seasons; Single-Blind Method; Sleep Phase Chronotherapy; Thiophenes

2012
A non-comparative assessment of tolerability and efficacy of duloxetine in the treatment of depressed patients with Parkinson's disease.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:16

    Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Parkinson Disease; Psychiatric Status Rating Scales; Quality of Life; Thiophenes; Treatment Outcome

2012
A randomized, double-blind trial of 2.5 mg and 5 mg vortioxetine (Lu AA21004) versus placebo for 8 weeks in adults with major depressive disorder.
    Current medical research and opinion, 2013, Volume: 29, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Piperazines; Placebos; Sexual Dysfunction, Physiological; Suicidal Ideation; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine

2013
Duloxetine in the long-term treatment of major depressive disorder.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:10

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antidepressive Agents; Chronic Disease; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Long-Term Care; Male; Middle Aged; Personality Inventory; Thiophenes; Treatment Outcome

2003
Duloxetine in the treatment of depression: a double-blind placebo-controlled comparison with paroxetine.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:4

    Topics: Adult; Analysis of Variance; Confidence Intervals; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Logistic Models; Male; Middle Aged; Paroxetine; Sleep Initiation and Maintenance Disorders; Thiophenes

2004
A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:9

    Topics: Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Sex Factors; Thiophenes; Treatment Outcome

2004
Duloxetine 60 mg once-daily in the treatment of painful physical symptoms in patients with major depressive disorder.
    Journal of psychiatric research, 2005, Volume: 39, Issue:1

    Topics: Administration, Oral; Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Placebos; Severity of Illness Index; Thiophenes; Treatment Outcome

2005
Incidence and duration of antidepressant-induced nausea: duloxetine compared with paroxetine and fluoxetine.
    Clinical therapeutics, 2004, Volume: 26, Issue:9

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Europe; Female; Fluoxetine; Humans; Male; Middle Aged; Nausea; Paroxetine; Prevalence; Severity of Illness Index; Sex Factors; Thiophenes; Time Factors; United States

2004
Duloxetine in the acute and long-term treatment of major depressive disorder: a placebo- and paroxetine-controlled trial.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2004, Volume: 14, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Body Weight; Cardiovascular Diseases; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Electrocardiography; Female; Hemodynamics; Humans; Longitudinal Studies; Male; Middle Aged; Paroxetine; Psychiatric Status Rating Scales; Sexual Dysfunction, Physiological; Thiophenes

2004
Sexual functioning assessed in 4 double-blind placebo- and paroxetine-controlled trials of duloxetine for major depressive disorder.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:6

    Topics: Adult; Antidepressive Agents; Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Incidence; Male; Middle Aged; Paroxetine; Placebos; Selective Serotonin Reuptake Inhibitors; Sexual Behavior; Sexual Dysfunctions, Psychological; Thiophenes; Treatment Outcome

2005
A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder.
    Pain, 2005, Dec-15, Volume: 119, Issue:1-3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Antidepressive Agents; Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Middle Aged; Pain Measurement; Placebo Effect; Quality of Life; Thiophenes; Treatment Outcome; United States; Women's Health

2005
Management of depression relapse: re-initiation of duloxetine treatment or dose increase.
    Journal of psychiatric research, 2006, Volume: 40, Issue:4

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Long-Term Care; Male; Middle Aged; Recurrence; Thiophenes; Treatment Outcome

2006
Duloxetine in the treatment of major depressive disorder: a placebo- and paroxetine-controlled trial.
    European psychiatry : the journal of the Association of European Psychiatrists, 2006, Volume: 21, Issue:6

    Topics: Adult; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Mass Screening; Middle Aged; Paroxetine; Placebo Effect; Prevalence; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes

2006
Duloxetine 60 mg once daily in the treatment of milder major depressive disorder.
    International journal of clinical practice, 2006, Volume: 60, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes; Treatment Outcome

2006
Duloxetine for the treatment of major depressive disorder: safety and tolerability associated with dose escalation.
    Depression and anxiety, 2007, Volume: 24, Issue:1

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Female; Humans; Long-Term Care; Male; Middle Aged; Personality Inventory; Thiophenes; Treatment Outcome

2007
Treatment benefits of duloxetine in major depressive disorder as assessed by number needed to treat.
    International clinical psychopharmacology, 2006, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2006
Duloxetine in the treatment of major depressive disorder: an assessment of the relationship between outcomes and episode characteristics.
    International clinical psychopharmacology, 2006, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes; Treatment Outcome

2006
Duloxetine increases stage 3 sleep and suppresses rapid eye movement (REM) sleep in patients with major depression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2007, Volume: 17, Issue:8

    Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Electroencephalography; Female; Humans; Male; Middle Aged; Polysomnography; Prospective Studies; Psychiatric Status Rating Scales; Sleep Stages; Sleep, REM; Thiophenes

2007
A randomized, double-blind comparison of duloxetine and venlafaxine in the treatment of patients with major depressive disorder.
    Journal of psychiatric research, 2008, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Antidepressive Agents; Cyclohexanols; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Severity of Illness Index; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2008
Once-daily duloxetine 60 mg in the treatment of major depressive disorder: multicenter, double-blind, randomized, paroxetine-controlled, non-inferiority trial in China, Korea, Taiwan and Brazil.
    Psychiatry and clinical neurosciences, 2007, Volume: 61, Issue:3

    Topics: Activities of Daily Living; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Blood Pressure; Brazil; China; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Heart Rate; Humans; Korea; Male; Middle Aged; Pain; Pain Measurement; Paroxetine; Psychiatric Status Rating Scales; Taiwan; Thiophenes; Weight Gain

2007
Duloxetine treatment of dysthymia and double depression: an open-label trial.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:5

    Topics: Adult; Depressive Disorder, Major; Duloxetine Hydrochloride; Dysthymic Disorder; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2007
Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder: an 8-week, double-blind, placebo-controlled trial.
    The American journal of psychiatry, 2007, Volume: 164, Issue:6

    Topics: Age Factors; Aged; Antidepressive Agents; Back Pain; Cognition Disorders; Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Geriatric Assessment; Humans; Male; Neuropsychological Tests; Pain; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Secondary Prevention; Thiophenes; Treatment Outcome

2007
Duloxetine versus escitalopram and placebo: an 8-month, double-blind trial in patients with major depressive disorder.
    Current medical research and opinion, 2007, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Aged; Algorithms; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Placebos; Remission Induction; Thiophenes; Treatment Outcome

2007
A comparative study of the efficacy of acute and continuation treatment with escitalopram versus duloxetine in patients with major depressive disorder.
    Current medical research and opinion, 2007, Volume: 23, Issue:7

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder, Major; Double-Blind Method; Drug Tolerance; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes

2007
Double-blind comparison of escitalopram and duloxetine in the acute treatment of major depressive disorder.
    Clinical drug investigation, 2007, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes

2007
Time to response for duloxetine 60 mg once daily versus placebo in elderly patients with major depressive disorder.
    International psychogeriatrics, 2008, Volume: 20, Issue:2

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Thiophenes; Time Factors

2008
The safety and tolerability of duloxetine in depressed elderly patients with and without medical comorbidity.
    International journal of clinical practice, 2007, Volume: 61, Issue:8

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Arthritis; Cardiovascular Diseases; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Pain Measurement; Severity of Illness Index; Thiophenes; Treatment Outcome

2007
Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:6

    Topics: Adult; Anxiety; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hot Flashes; Humans; Middle Aged; Pain; Postmenopause; Selective Serotonin Reuptake Inhibitors; Single-Blind Method; Sleep Wake Disorders; Thiophenes; Treatment Outcome

2007
Long-term tolerability and effectiveness of duloxetine in the treatment of major depressive disorder.
    Depression and anxiety, 2008, Volume: 25, Issue:5

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Long-Term Care; Male; Middle Aged; Patient Dropouts; Personality Inventory; Psychometrics; Recurrence; Substance Withdrawal Syndrome; Thiophenes; Treatment Outcome

2008
Changes in sexual functioning associated with duloxetine, escitalopram, and placebo in the treatment of patients with major depressive disorder.
    The journal of sexual medicine, 2007, Volume: 4, Issue:4 Pt 1

    Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Sexual Behavior; Sexual Dysfunctions, Psychological; Surveys and Questionnaires; Thiophenes

2007
Duloxetine in the treatment of major depressive disorder: an open-label study.
    BMC psychiatry, 2007, Aug-28, Volume: 7

    Topics: Chronic Disease; Depressive Disorder, Major; Disability Evaluation; Duloxetine Hydrochloride; Humans; Quality of Life; Remission Induction; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Sexual Dysfunction, Physiological; Surveys and Questionnaires; Thiophenes; Treatment Outcome

2007
A randomized, controlled trial of duloxetine alone vs. duloxetine plus a telephone intervention in the treatment of depression.
    Journal of affective disorders, 2008, Volume: 108, Issue:1-2

    Topics: Adult; Ambulatory Care; Antidepressive Agents; Combined Modality Therapy; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Patient Compliance; Personality Inventory; Referral and Consultation; Telephone; Thiophenes; Treatment Outcome

2008
Differential antidepressant symptom efficacy: placebo-controlled comparisons of duloxetine and SSRIs (fluoxetine, paroxetine, escitalopram).
    Neuropsychobiology, 2007, Volume: 56, Issue:2-3

    Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome

2007
Efficacy and safety of duloxetine 60 mg once daily in the treatment of pain in patients with major depressive disorder and at least moderate pain of unknown etiology: a randomized controlled trial.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Severity of Illness Index; Thiophenes

2007
A comparison of initial duloxetine dosing strategies in patients with major depressive disorder.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Food-Drug Interactions; Humans; Male; Middle Aged; Outpatients; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2007
Safety and tolerability of duloxetine at 60 mg once daily in elderly patients with major depressive disorder.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:1

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Thiophenes

2008
Rescue pharmacotherapy with duloxetine for selective serotonin reuptake inhibitor nonresponders in late-life depression: outcome and tolerability.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:3

    Topics: Age of Onset; Aged; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Duloxetine Hydrochloride; Female; Humans; Male; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Surveys and Questionnaires; Thiophenes; Treatment Outcome

2008
Switching to duloxetine from selective serotonin reuptake inhibitor antidepressants: a multicenter trial comparing 2 switching techniques.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:1

    Topics: Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes

2008
Duloxetine in the treatment of major depressive disorder: a double-blind clinical trial.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Blood Pressure; Body Weight; Depressive Disorder, Major; Dopamine Uptake Inhibitors; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2002

Other Studies

139 other study(ies) available for thiophenes and Depressive Disorder, Major

ArticleYear
Determination of Patient Adherence for Duloxetine in Urine.
    Journal of analytical toxicology, 2022, Oct-14, Volume: 46, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Creatinine; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Norepinephrine; Patient Compliance; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Young Adult

2022
Effects of adjunctive brexpiprazole on sleep-wake and circadian parameters in youth with depressive disorders: study protocol for a clinical trial.
    BMJ open, 2022, 09-06, Volume: 12, Issue:9

    Topics: Adolescent; Depressive Disorder, Major; Humans; Quinolones; Sleep; Sleep Wake Disorders; Thiophenes; Young Adult

2022
Comparisons of global tests on intersection hypotheses and their application in matched parallel gatekeeping procedures.
    Journal of biopharmaceutical statistics, 2020, 07-03, Volume: 30, Issue:4

    Topics: Antidepressive Agents; Clinical Trials, Phase III as Topic; Computer Simulation; Data Interpretation, Statistical; Depressive Disorder, Major; Dose-Response Relationship, Drug; Endpoint Determination; Humans; Models, Statistical; Quinolones; Randomized Controlled Trials as Topic; Research Design; Thiophenes; Treatment Outcome

2020
Chronobiologic parameter changes in patients with major depressive disorder and sleep disturbance treated with adjunctive brexpiprazole: An open-label, flexible-dose, exploratory substudy.
    Journal of affective disorders, 2021, 01-01, Volume: 278

    Topics: Circadian Rhythm; Depressive Disorder, Major; Drug Therapy, Combination; Humans; Melatonin; Quinolones; Sleep; Thiophenes; Treatment Outcome

2021
Agonist E-6837 and antagonist SB-271046 of 5-HT6 receptors both reverse the depressive-like effect induced in mice by subchronic ketamine administration.
    Behavioural pharmacology, 2017, Volume: 28, Issue:7

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Depression; Depressive Disorder, Major; Disease Models, Animal; Hindlimb Suspension; Indoles; Ketamine; Male; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Schizophrenia; Sulfonamides; Swimming; Thiophenes

2017
Alterations in amino acid levels in mouse brain regions after adjunctive treatment of brexpiprazole with fluoxetine: comparison with (R)-ketamine.
    Psychopharmacology, 2017, Volume: 234, Issue:21

    Topics: Administration, Oral; Amino Acids; Animals; Antidepressive Agents; Brain; Depressive Disorder, Major; Fluoxetine; Ketamine; Male; Mice; Mice, Inbred C57BL; Quinolones; Receptors, N-Methyl-D-Aspartate; Thiophenes

2017
The use of brexpiprazole amongst individuals with insufficient outcomes with aripiprazole or bupropion: A case series.
    Perspectives in psychiatric care, 2018, Volume: 54, Issue:4

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Bupropion; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; New York; Psychiatric Status Rating Scales; Quinolones; Retrospective Studies; Thiophenes; Treatment Outcome; Young Adult

2018
Changes in healthcare resource use and costs associated with early versus delayed initiation of atypical antipsychotic adjunctive treatment in major depressive disorder.
    Journal of medical economics, 2018, Volume: 21, Issue:9

    Topics: Adult; Age Factors; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Comorbidity; Depressive Disorder, Major; Drug Administration Schedule; Drug Therapy, Combination; Female; Health Expenditures; Health Resources; Health Services; Humans; Insurance Claim Review; Lurasidone Hydrochloride; Male; Middle Aged; Models, Econometric; Quetiapine Fumarate; Quinolones; Residence Characteristics; Retrospective Studies; Sex Factors; Socioeconomic Factors; Thiophenes; Time-to-Treatment

2018
The effects of brexpiprazole and aripiprazole on body weight as monotherapy in patients with schizophrenia and as adjunctive treatment in patients with major depressive disorder: an analysis of short-term and long-term studies.
    International clinical psychopharmacology, 2018, Volume: 33, Issue:5

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Depressive Disorder, Major; Female; Humans; Longitudinal Studies; Male; Meta-Analysis as Topic; Middle Aged; Quinolones; Randomized Controlled Trials as Topic; Schizophrenia; Thiophenes; Weight Gain

2018
Adjunctive brexpiprazole for elderly patients with major depressive disorder: An open-label, long-term safety and tolerability study.
    International journal of geriatric psychiatry, 2018, Volume: 33, Issue:10

    Topics: Aged; Aged, 80 and over; Akathisia, Drug-Induced; Antidepressive Agents; Chemotherapy, Adjuvant; Depressive Disorder, Major; Europe; Fatigue; Female; Humans; Male; Quality of Life; Quinolones; Social Participation; Thiophenes; United States

2018
Medication Adherence, Health Care Utilization, and Costs in Patients With Major Depressive Disorder Initiating Adjunctive Atypical Antipsychotic Treatment.
    Clinical therapeutics, 2019, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Depressive Disorder, Major; Emergency Service, Hospital; Female; Health Care Costs; Hospitalization; Humans; Lurasidone Hydrochloride; Male; Medicaid; Medicare; Medication Adherence; Middle Aged; Patient Acceptance of Health Care; Quetiapine Fumarate; Quinolones; Thiophenes; United States; Young Adult

2019
A pilot study of brexpiprazole for bipolar depression.
    Journal of affective disorders, 2019, Apr-15, Volume: 249

    Topics: Adult; Antidepressive Agents; Bipolar Disorder; Cognition; Depressive Disorder, Major; Female; Humans; Irritable Mood; Male; Middle Aged; Pilot Projects; Psychiatric Status Rating Scales; Quality of Life; Quinolones; Thiophenes; Treatment Outcome; Young Adult

2019
Activating and Sedating Properties of Medications Used for the Treatment of Major Depressive Disorder and Their Effect on Patient Functioning.
    The Journal of clinical psychiatry, 2019, 04-30, Volume: 80, Issue:3

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Anxiety Disorders; Aripiprazole; Arousal; Comorbidity; Delayed-Action Preparations; Depressive Disorder, Major; Drug Approval; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Practice Patterns, Physicians'; Quality of Life; Quetiapine Fumarate; Quinolones; Sleep Initiation and Maintenance Disorders; Thiophenes

2019
Collagenous colitis and ileitis under treatment with duloxetine.
    Acta gastro-enterologica Belgica, 2012, Volume: 75, Issue:4

    Topics: Aged; Antidepressive Agents; Biopsy; Chronic Disease; Colitis, Collagenous; Colon; Colonoscopy; Depressive Disorder, Major; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Ileitis; Ileum; Recurrence; Thiophenes; Treatment Outcome; Withholding Treatment

2012
Effectiveness and tolerability of duloxetine in 2 different ethnic samples: a prospective observational cohort study.
    Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:2

    Topics: Adult; American Indian or Alaska Native; Antidepressive Agents; Cohort Studies; Depressive Disorder, Major; Duloxetine Hydrochloride; Ethnicity; Female; Humans; Male; Middle Aged; Prospective Studies; Spain; Thiophenes; Treatment Outcome; White People

2013
Longitudinal analysis of healthcare costs: a case study of patients with major depressive disorder treated with duloxetine.
    Journal of medical economics, 2013, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Age Factors; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Health Expenditures; Humans; Insurance, Health; Longitudinal Studies; Male; Middle Aged; Residence Characteristics; Retrospective Studies; Sex Factors; Thiophenes; Young Adult

2013
Duloxetine-induced life-threatening long QT syndrome.
    Wiener klinische Wochenschrift, 2013, Volume: 125, Issue:5-6

    Topics: Antidepressive Agents; Arrhythmia, Sinus; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Long QT Syndrome; Middle Aged; Thiophenes

2013
Duloxetine and pregnancy outcomes: safety surveillance findings.
    International journal of medical sciences, 2013, Volume: 10, Issue:4

    Topics: Abortion, Spontaneous; Adult; Adverse Drug Reaction Reporting Systems; Antidepressive Agents; Depressive Disorder, Major; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Female; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Thiophenes; United States; United States Food and Drug Administration

2013
Three-arm noninferiority trials with a prespecified margin for inference of the difference in the proportions of binary endpoints.
    Journal of biopharmaceutical statistics, 2013, Volume: 23, Issue:4

    Topics: Antidepressive Agents; Confidence Intervals; Data Interpretation, Statistical; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Endpoint Determination; Humans; Models, Statistical; Monte Carlo Method; Placebos; Randomized Controlled Trials as Topic; Research Design; Sample Size; Thiophenes; Treatment Outcome

2013
VEGF plasma level variations in duloxetine-treated patients with major depression.
    Journal of affective disorders, 2013, Volume: 151, Issue:2

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Vascular Endothelial Growth Factor A

2013
Local control for identifying subgroups of interest in observational research: persistence of treatment for major depressive disorder.
    International journal of methods in psychiatric research, 2013, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Age Factors; Caregivers; Cluster Analysis; Cyclohexanols; Data Mining; Decision Making; Delayed-Action Preparations; Depressive Disorder, Major; Drug Costs; Duloxetine Hydrochloride; Female; Health Education; Humans; Insurance Claim Reporting; Male; Middle Aged; Observational Studies as Topic; Outcome and Process Assessment, Health Care; Statistics as Topic; Statistics, Nonparametric; Thiophenes; Venlafaxine Hydrochloride; Young Adult

2013
Impact of patient selection and study characteristics on signal detection in placebo-controlled trials with antidepressants.
    Journal of psychiatric research, 2014, Volume: 51

    Topics: Adult; Analysis of Variance; Antidepressive Agents; Databases, Factual; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Patient Selection; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Research Design; Signal Detection, Psychological; Thiophenes; Young Adult

2014
Response to antidepressant medications in late-life depression across the spectrum of cognitive functioning.
    The Journal of clinical psychiatry, 2014, Volume: 75, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Aripiprazole; Citalopram; Cognitive Dysfunction; Cyclohexanols; Dementia; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Piperazines; Quinolones; Randomized Controlled Trials as Topic; Recurrence; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Venlafaxine Hydrochloride

2014
Burning paresthesia related to duloxetine therapy.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Paresthesia; Selective Serotonin Reuptake Inhibitors; Thiophenes

2014
Duloxetine may enhance control of pain related to bladder trauma.
    The Australian and New Zealand journal of psychiatry, 2014, Volume: 48, Issue:9

    Topics: Analgesics; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Pelvic Pain; Thiophenes; Treatment Outcome; Young Adult

2014
Coding of adverse events of suicidality in clinical study reports of duloxetine for the treatment of major depressive disorder: descriptive study.
    BMJ (Clinical research ed.), 2014, Jun-04, Volume: 348

    Topics: Adrenergic Uptake Inhibitors; Adverse Drug Reaction Reporting Systems; Antidepressive Agents; Clinical Coding; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Suicide; Thiophenes

2014
Digging for data on harms in duloxetine trials.
    BMJ (Clinical research ed.), 2014, Jun-04, Volume: 348

    Topics: Adrenergic Uptake Inhibitors; Adverse Drug Reaction Reporting Systems; Antidepressive Agents; Clinical Coding; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Suicide; Thiophenes

2014
Effects of low-dose olanzapine on duloxetine-related nausea and vomiting for the treatment of major depressive disorder.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:4

    Topics: Adolescent; Adult; Antidepressive Agents; Antiemetics; Benzodiazepines; Depressive Disorder, Major; Drug Administration Schedule; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Nausea; Olanzapine; Thiophenes; Treatment Outcome; Vomiting; Young Adult

2014
Pharmacokinetics of orally administered duloxetine in children and adolescents with major depressive disorder.
    Clinical pharmacokinetics, 2014, Volume: 53, Issue:8

    Topics: Administration, Oral; Adolescent; Age Factors; Antidepressive Agents; Child; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Models, Biological; Randomized Controlled Trials as Topic; Thiophenes

2014
Individual residual symptoms and functional impairment in patients with depression.
    Psychiatry research, 2014, Dec-15, Volume: 220, Issue:1-2

    Topics: Adult; Antidepressive Agents; Anxiety; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Sleep Wake Disorders; Thiophenes

2014
Brexpiprazole: another multipurpose antipsychotic drug?
    Journal of psychosocial nursing and mental health services, 2015, Volume: 53, Issue:4

    Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Depressive Disorder, Major; Humans; Psychomotor Agitation; Quinolones; Schizophrenia; Stress Disorders, Post-Traumatic; Thiophenes

2015
Multimodal functional and structural neuroimaging investigation of major depressive disorder following treatment with duloxetine.
    BMC psychiatry, 2015, Apr-14, Volume: 15

    Topics: Adult; Brain; Brain Mapping; Depressive Disorder, Major; Duloxetine Hydrochloride; Echo-Planar Imaging; Emotions; Facial Expression; Female; Functional Neuroimaging; Humans; Imaging, Three-Dimensional; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Multimodal Imaging; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Stroop Test; Thiophenes

2015
The ABC's of dopamine receptor partial agonists - aripiprazole, brexpiprazole and cariprazine: the 15-min challenge to sort these agents out.
    International journal of clinical practice, 2015, Volume: 69, Issue:11

    Topics: Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Depressive Disorder, Major; Dopamine Agonists; Drug Administration Schedule; Drug Interactions; Humans; Piperazines; Quinolones; Schizophrenia; Thiophenes

2015
Mechanism of action of brexpiprazole: comparison with aripiprazole.
    CNS spectrums, 2016, Volume: 21, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Antipsychotic Agents; Aripiprazole; Depressive Disorder, Major; Dopamine Agonists; Humans; Quinolones; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D2; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Agents; Thiophenes

2016
Cost-effectiveness of brexpiprazole adjunctive treatment for major depressive disorder.
    Journal of affective disorders, 2017, Jan-01, Volume: 207

    Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Cost-Benefit Analysis; Depressive Disorder, Major; Disorders of Excessive Somnolence; Drug Costs; Drug Therapy, Combination; Fatigue; Female; Health Care Costs; Humans; Male; Middle Aged; Models, Economic; Olanzapine; Patient Selection; Quetiapine Fumarate; Quinolones; Serotonin Agents; Thiophenes; Weight Gain; Young Adult

2017
Adjunctive brexpiprazole for the treatment of major depressive disorder.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:17

    Topics: Antidepressive Agents; Antipsychotic Agents; Chemotherapy, Adjuvant; Depressive Disorder, Major; Dopamine; Humans; Quinolones; Randomized Controlled Trials as Topic; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT1; Serotonin 5-HT1 Receptor Agonists; Thiophenes; Treatment Outcome

2016
Adjunctive treatment of brexpiprazole with fluoxetine shows a rapid antidepressant effect in social defeat stress model: Role of BDNF-TrkB signaling.
    Scientific reports, 2016, 12-19, Volume: 6

    Topics: Animals; Antidepressive Agents; Azepines; Behavior, Animal; Benzamides; Brain-Derived Neurotrophic Factor; Dendritic Spines; Depressive Disorder, Major; Disease Models, Animal; Drug Therapy, Combination; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Phenotype; Quinolones; Receptor, trkB; Selective Serotonin Reuptake Inhibitors; Signal Transduction; Thiophenes

2016
Efficacy of Brexpiprazole as Adjunctive Treatment in Major Depressive Disorder With Irritability: Post Hoc Analysis of 2 Pivotal Clinical Studies.
    Journal of clinical psychopharmacology, 2017, Volume: 37, Issue:2

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Drug Therapy, Combination; Humans; Irritable Mood; Middle Aged; Quinolones; Thiophenes

2017
Severe and symptomatic hyponatremia following duloxetine treatment.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:3

    Topics: Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Hyponatremia; Severity of Illness Index; Thiophenes

2009
Non-fatal overdose of duloxetine in combination with other antidepressants and benzodiazepines.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 2

    Topics: Affect; Aged; Antidepressive Agents; Chromatography, High Pressure Liquid; Confusion; Depressive Disorder, Major; Drug Interactions; Drug Overdose; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gastric Lavage; Humans; Life Change Events; Metabolic Clearance Rate; Suicide, Attempted; Thiophenes

2009
Measurement of pain and medication effect in a study of duloxetine.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:6

    Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Prevalence; Severity of Illness Index; Thiophenes

2008
Duloxetine treatment of social anxiety disorder with comorbid major depression.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Anxiety Disorders; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes

2008
[Chronic pain and depression].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2008, Volume: 108, Issue:11

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Chronic Disease; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Prevalence; Thiophenes

2008
Clinical outcome and tolerability of duloxetine in the treatment of major depressive disorder: a 12-week study with plasma levels.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:8

    Topics: Adrenergic Uptake Inhibitors; Aged; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome

2010
Serotonin syndrome induced by duloxetine.
    The Australian and New Zealand journal of psychiatry, 2009, Volume: 43, Issue:6

    Topics: Aged; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Thiophenes

2009
Duloxetine and care management treatment of older adults with comorbid major depressive disorder and chronic low back pain: results of an open-label pilot study.
    International journal of geriatric psychiatry, 2010, Volume: 25, Issue:6

    Topics: Aged; Anxiety; Chronic Disease; Comorbidity; Depressive Disorder, Major; Disability Evaluation; Disease Management; Duloxetine Hydrochloride; Female; Health Status; Humans; Low Back Pain; Male; Pain Measurement; Pilot Projects; Psychiatric Status Rating Scales; Quality of Life; Selective Serotonin Reuptake Inhibitors; Self Efficacy; Sleep; Surveys and Questionnaires; Thiophenes

2010
Relationship between TSH levels in the normal range and short-term duloxetine efficacy.
    Journal of affective disorders, 2010, Volume: 123, Issue:1-3

    Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Meta-Analysis as Topic; Middle Aged; Personality Inventory; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Thyrotropin; Treatment Outcome

2010
Duloxetine related effects of brain structure on a patient of major depressive disorder with panic disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Feb-01, Volume: 34, Issue:1

    Topics: Adult; Antidepressive Agents; Brain; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Panic Disorder; Thiophenes

2010
Major Depressive Disorder in recovery and neuropsychological functioning: effects of selective serotonin reuptake inhibitor and dual inhibitor depression treatments on residual cognitive deficits in patients with Major Depressive Disorder in recovery.
    Journal of affective disorders, 2010, Volume: 123, Issue:1-3

    Topics: Adult; Antidepressive Agents; Citalopram; Cognition Disorders; Controlled Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Personality Inventory; Reference Values; Selective Serotonin Reuptake Inhibitors; Thiophenes; Wechsler Scales

2010
Anxiety does not predict response to duloxetine in major depression: results of a pooled analysis of individual patient data from 11 placebo-controlled trials.
    Depression and anxiety, 2010, Volume: 27, Issue:1

    Topics: Adult; Antidepressive Agents; Anxiety Disorders; Comorbidity; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Meta-Analysis as Topic; Middle Aged; Personality Inventory; Prognosis; Psychometrics; Randomized Controlled Trials as Topic; Retrospective Studies; Thiophenes; Treatment Outcome

2010
A case study of salami slicing: pooled analyses of duloxetine for depression.
    Psychotherapy and psychosomatics, 2010, Volume: 79, Issue:2

    Topics: Advertising; Antidepressive Agents; Clinical Trials as Topic; Conflict of Interest; Depressive Disorder, Major; Drug Industry; Duloxetine Hydrochloride; Humans; Meta-Analysis as Topic; Publishing; Thiophenes; Treatment Outcome

2010
Duloxetine-modulating effects of brain structure in major depressive disorder with panic disorder.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Adult; Brain; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Magnetic Resonance Imaging; Male; Panic Disorder; Selective Serotonin Reuptake Inhibitors; Thiophenes

2010
Management of depression in the presence of pain symptoms.
    Psychiatria Danubina, 2010, Volume: 22, Issue:1

    Topics: Antidepressive Agents; Brain; Chronic Disease; Clinical Trials as Topic; Combined Modality Therapy; Comorbidity; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Fibromyalgia; Humans; Milnacipran; Mind-Body Relations, Metaphysical; Norepinephrine; Pain; Psychotherapy; Serotonin; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2010
Effects of selective serotonin reuptake and dual serotonergic-noradrenergic reuptake treatments on attention and executive functions in patients with major depressive disorder.
    Psychiatry research, 2010, May-30, Volume: 177, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Adult; Attention Deficit Disorder with Hyperactivity; Citalopram; Cognition Disorders; Depressive Disorder, Major; Duloxetine Hydrochloride; Executive Function; Female; Humans; Male; Neuropsychological Tests; Psychometrics; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Young Adult

2010
A subtle grey-matter increase in first-episode, drug-naive major depressive disorder with panic disorder after 6 weeks' duloxetine therapy.
    The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:2

    Topics: Antidepressive Agents; Brain; Cerebellum; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Male; Panic Disorder; Psychiatric Status Rating Scales; Temporal Lobe; Thiophenes; Time Factors; Treatment Outcome

2011
Effects of duloxetine treatment on brain response to painful stimulation in major depressive disorder.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:11

    Topics: Adult; Brain; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Pain; Pain Measurement; Thiophenes; Treatment Outcome

2010
Cost effectiveness of escitalopram versus SNRIs in second-step treatment of major depressive disorder in Sweden.
    Journal of medical economics, 2010, Volume: 13, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Citalopram; Cyclohexanols; Decision Support Techniques; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Markov Chains; Outcome Assessment, Health Care; Quality-Adjusted Life Years; Recurrence; Remission Induction; Selective Serotonin Reuptake Inhibitors; Sweden; Thiophenes; Venlafaxine Hydrochloride

2010
Initial duloxetine prescription dose and treatment adherence and persistence in patients with major depressive disorder.
    International clinical psychopharmacology, 2010, Volume: 25, Issue:6

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Depressive Disorder, Major; Drug Prescriptions; Duloxetine Hydrochloride; Female; Humans; Male; Managed Care Programs; Medical Records; Medication Adherence; Middle Aged; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Young Adult

2010
Long-term safety of duloxetine during open-label compassionate use treatment of patients who completed previous duloxetine clinical trials.
    Current medical research and opinion, 2010, Volume: 26, Issue:11

    Topics: Adult; Antidepressive Agents; Compassionate Use Trials; Depressive Disorder, Major; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Female; Humans; Male; Medication Adherence; Middle Aged; Outcome Assessment, Health Care; Thiophenes; Time

2010
[The weeping patient].
    MMW Fortschritte der Medizin, 2010, Sep-23, Volume: 152, Issue:38

    Topics: Antidepressive Agents; Crying; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Physician-Patient Relations; Primary Health Care; Thiophenes

2010
Factors associated with duloxetine treatment among patients with major depressive disorder in Veterans Health Administration: a retrospective study.
    Current medical research and opinion, 2010, Volume: 26, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors; Socioeconomic Factors; Thiophenes; United States; United States Department of Veterans Affairs; Veterans Health; Young Adult

2010
Duloxetine in major depressed patients resistant to SSRIs and/or venlafaxine.
    Psychiatria Danubina, 2010, Volume: 22 Suppl 1

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder, Major; Drug Resistance; Duloxetine Hydrochloride; Humans; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes

2010
A case of venlafaxine-induced bruxism alleviated by duloxetine substitution.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jan-15, Volume: 35, Issue:1

    Topics: Aged; Antidepressive Agents; Bruxism; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Thiophenes; Venlafaxine Hydrochloride

2011
Aripiprazole augmentation induced hypertension in major depressive disorder: a case report.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jan-15, Volume: 35, Issue:1

    Topics: Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Depressive Disorder, Major; Drug Synergism; Duloxetine Hydrochloride; Female; Humans; Hypertension; Middle Aged; Piperazines; Quinolones; Thiophenes

2011
[Effective treatment of depression. Early reduction of painful concomitant symptoms increases the probability of remission].
    MMW Fortschritte der Medizin, 2010, Nov-04, Volume: 152, Issue:44

    Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Early Diagnosis; General Practice; Humans; Pain; Quality of Life; Somatoform Disorders; Thiophenes

2010
[Interview with Dr. Armin Spingler. Management of depression in family practice].
    MMW Fortschritte der Medizin, 2010, Nov-04, Volume: 152, Issue:44

    Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; General Practice; Humans; Medication Adherence; Pain; Somatoform Disorders; Thiophenes

2010
False conclusions regarding duloxetine's purported efficacy in pain among depressed patients.
    Psychiatria Danubina, 2010, Volume: 22, Issue:4

    Topics: Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2010
On the three-arm non-inferiority trial including a placebo with a prespecified margin.
    Statistics in medicine, 2011, Feb-10, Volume: 30, Issue:3

    Topics: Algorithms; Antidepressive Agents; Computer Simulation; Confidence Intervals; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Models, Statistical; Monte Carlo Method; Multicenter Studies as Topic; Normal Distribution; Paroxetine; Placebos; Randomized Controlled Trials as Topic; Sample Size; Thiophenes; Treatment Outcome

2011
Adherence and persistence with duloxetine and hospital utilization in patients with major depressive disorder.
    International clinical psychopharmacology, 2011, Volume: 26, Issue:3

    Topics: Adult; Antidepressive Agents; Databases, Factual; Depressive Disorder, Major; Duloxetine Hydrochloride; Hospitalization; Humans; Medication Adherence; Middle Aged; Thiophenes; Time Factors; Young Adult

2011
Treatment patterns associated with Duloxetine and Venlafaxine use for Major Depressive Disorder.
    BMC psychiatry, 2011, Jan-31, Volume: 11

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Cyclohexanols; Depressive Disorder, Major; Drug Costs; Duloxetine Hydrochloride; Female; Health Care Costs; Humans; Male; Middle Aged; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2011
Measurement-based care in psychiatric practice: a policy framework for implementation.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:8

    Topics: Adult; Antidepressive Agents; Cooperative Behavior; Depressive Disorder, Major; Disease Management; Duloxetine Hydrochloride; Female; Health Plan Implementation; Humans; Interdisciplinary Communication; Medication Adherence; Outcome and Process Assessment, Health Care; Standard of Care; Surveys and Questionnaires; Thiophenes

2011
Hypogonadism and gynecomastia with duloxetine.
    Pharmacopsychiatry, 2011, Volume: 44, Issue:2

    Topics: Bulimia Nervosa; Depressive Disorder, Major; Duloxetine Hydrochloride; Gynecomastia; Humans; Hypogonadism; Male; Mastectomy; Selective Serotonin Reuptake Inhibitors; Thiophenes; Young Adult

2011
Atypical Stevens-Johnson syndrome in an adolescent treated with duloxetine.
    Journal of child and adolescent psychopharmacology, 2011, Volume: 21, Issue:1

    Topics: Adolescent; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Stevens-Johnson Syndrome; Thiophenes

2011
Duloxetine transfer across the placenta during pregnancy and into milk during lactation.
    Archives of women's mental health, 2011, Volume: 14, Issue:2

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Lactation; Milk, Human; Placenta; Pregnancy; Thiophenes

2011
Treatment adherence and persistence with duloxetine, venlafaxine XR, and escitalopram among patients with major depressive disorder and chronic pain-related diseases.
    Current medical research and opinion, 2011, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Algorithms; Antidepressive Agents; Chronic Disease; Citalopram; Cyclohexanols; Depressive Disorder, Major; Dosage Forms; Duloxetine Hydrochloride; Female; Humans; Male; Medication Adherence; Middle Aged; Pain; Retrospective Studies; Somatoform Disorders; Thiophenes; Venlafaxine Hydrochloride; Young Adult

2011
Plasma kynurenine levels are elevated in suicide attempters with major depressive disorder.
    Brain, behavior, and immunity, 2011, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Cytokines; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Hypericum; Impulsive Behavior; Inflammation; Kynurenine; Male; Middle Aged; Neopterin; Phytotherapy; Recurrence; Serotonin; Smoking; Suicide, Attempted; Thiophenes; Tryptophan; Young Adult

2011
Duloxetine-related growth of putamen and brainstem in first-onset drug-naive major depressive disorder with panic disorder: a case series.
    The Journal of neuropsychiatry and clinical neurosciences, 2011,Spring, Volume: 23, Issue:2

    Topics: Adult; Antidepressive Agents; Brain Stem; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Magnetic Resonance Imaging; Male; Organ Size; Panic Disorder; Putamen; Thiophenes

2011
Duloxetine-induced subcortical growth in a patient with major depressive disorder and panic disorder.
    The Journal of neuropsychiatry and clinical neurosciences, 2011,Spring, Volume: 23, Issue:2

    Topics: Adult; Antidepressive Agents; Brain Stem; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Organ Size; Panic Disorder; Putamen; Thiophenes

2011
Association of catechol-O-methyltransferase variants with duloxetine response in major depressive disorder.
    Psychiatry research, 2011, Oct-30, Volume: 189, Issue:3

    Topics: Adult; Antidepressive Agents; Catechol O-Methyltransferase; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Genome-Wide Association Study; Humans; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Sex Factors; Thiophenes

2011
Electroretinographic assessment in major depressed patients receiving duloxetine: might differences between responders and non-responders indicate a differential biological background?
    Journal of affective disorders, 2011, Volume: 135, Issue:1-3

    Topics: Adult; Antidepressive Agents; Case-Control Studies; Depression; Depressive Disorder; Depressive Disorder, Major; Dopamine; Duloxetine Hydrochloride; Electroretinography; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Sample Size; Thiophenes; Treatment Outcome

2011
Safety of electroconvulsive therapy-duloxetine combination.
    The journal of ECT, 2011, Volume: 27, Issue:3

    Topics: Antidepressive Agents; Antipsychotic Agents; Combined Modality Therapy; Depressive Disorder, Major; Dibenzothiazepines; Duloxetine Hydrochloride; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Quetiapine Fumarate; Suicidal Ideation; Thiophenes; Treatment Outcome

2011
Effects of baseline depression severity on remission rates with duloxetine and placebo in anxious and nonanxious patients with major depression.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:5

    Topics: Adult; Antidepressive Agents; Anxiety Disorders; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Logistic Models; Male; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Severity of Illness Index; Thiophenes; Treatment Outcome

2011
Trajectory analysis of healthcare costs for patients with major depressive disorder treated with high doses of duloxetine.
    Journal of medical economics, 2011, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Follow-Up Studies; Health Care Costs; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Regression Analysis; Retrospective Studies; Thiophenes; United States; Young Adult

2011
Duloxetine's effects in resting functional magnetic resonance imaging of first-episode, drug-naive major depressive disorder with panic disorder patients.
    The Journal of neuropsychiatry and clinical neurosciences, 2011,Summer, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Antidepressive Agents; Brain; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Magnetic Resonance Imaging; Male; Panic Disorder; Rest; Thiophenes

2011
Comparative effectiveness in pain-related outcomes and health care utilizations between veterans with major depressive disorder treated with duloxetine and other antidepressants: a retrospective propensity score-matched comparison.
    Pain practice : the official journal of World Institute of Pain, 2012, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Aged; Analgesics; Antidepressive Agents; Chronic Pain; Cohort Studies; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain Measurement; Retrospective Studies; Thiophenes; Veterans; Young Adult

2012
Partial status epilepticus after electroconvulsive therapy and medical treatment with bupropion.
    Pharmacopsychiatry, 2011, Volume: 44, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bupropion; Depressive Disorder, Major; Duloxetine Hydrochloride; Electroconvulsive Therapy; Electroencephalography; Humans; Male; Seizures; Status Epilepticus; Thiophenes

2011
Early discontinuation and suboptimal dosing of duloxetine treatment in patients with major depressive disorder: analysis from a US third-party payer perspective.
    Journal of medical economics, 2012, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Insurance, Health, Reimbursement; Logistic Models; Male; Middle Aged; Thiophenes; United States; Withholding Treatment; Young Adult

2012
Duloxetine in the acute and continuation treatment of major depressive disorder.
    Expert review of neurotherapeutics, 2011, Volume: 11, Issue:11

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Thiophenes

2011
Dosing patterns for duloxetine and predictors of high-dose prescriptions in patients with major depressive disorder: analysis from a United States third-party payer perspective.
    Clinical therapeutics, 2011, Volume: 33, Issue:11

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multivariate Analysis; Thiophenes; United States

2011
Frequency of treatment-emergent sexual dysfunction and treatment effectiveness during SSRI or duloxetine therapy: 8-week data from a 6-month observational study.
    International journal of psychiatry in clinical practice, 2011, Volume: 15, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Adult; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Quality of Life; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunctions, Psychological; Thiophenes

2011
Treatment-emergent sexual dysfunction with SSRIs and duloxetine: effectiveness and functional outcomes over a 6-month observational period.
    International journal of psychiatry in clinical practice, 2011, Volume: 15, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Adult; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Prospective Studies; Quality of Life; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunctions, Psychological; Thiophenes

2011
Time course of improvement of different symptom clusters in patients with major depression and pain treated with duloxetine or placebo.
    Current medical research and opinion, 2012, Volume: 28, Issue:1

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Multicenter Studies as Topic; Pain; Pain Measurement; Placebos; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index; Thiophenes; Time Factors; Treatment Outcome

2012
Frontal regional homogeneity increased and temporal regional homogeneity decreased after remission of first-episode drug-naïve major depressive disorder with panic disorder patients under duloxetine therapy for 6 weeks.
    Journal of affective disorders, 2012, Volume: 136, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Panic Disorder; Remission Induction; Temporal Lobe; Thiophenes

2012
Pharmacogenetic investigation of response to duloxetine treatment in generalized anxiety disorder.
    The pharmacogenomics journal, 2013, Volume: 13, Issue:3

    Topics: Adult; Anxiety Disorders; Biomarkers, Pharmacological; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Genetic Association Studies; Humans; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Receptors, Corticotropin-Releasing Hormone; Thiophenes

2013
Agomelatine-induced akathisia with concomitant duloxetine medication: a case report.
    Pharmacopsychiatry, 2012, Volume: 45, Issue:4

    Topics: Acetamides; Adult; Akathisia, Drug-Induced; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Hypnotics and Sedatives; Thiophenes

2012
Generalized tonic-clonic seizure secondary to duloxetine poisoning: a short report with favorable out come.
    Neurotoxicology, 2012, Volume: 33, Issue:2

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Electroencephalography; Humans; Male; Status Epilepticus; Thiophenes

2012
Healthcare utilization among patients with depression before and after initiating duloxetine in the United Kingdom.
    Journal of medical economics, 2012, Volume: 15, Issue:4

    Topics: Adult; Aged; Analgesics; Antidepressive Agents; Databases, Factual; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Health Services Needs and Demand; Hospitalization; Humans; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Thiophenes; United Kingdom

2012
Fast versus slow onset of depressive episodes: a clinical criterion for subtyping patients with major depression.
    European psychiatry : the journal of the Association of European Psychiatrists, 2013, Volume: 28, Issue:5

    Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Life Change Events; Male; Middle Aged; Suicide, Attempted; Thiophenes; Time Factors

2013
Tolerability aspects in duloxetine-treated patients with depression: Should one use a lower starting dose in clinical practice?
    Expert opinion on drug safety, 2012, Volume: 11, Issue:5

    Topics: Adult; Aged; Analgesics; Antidepressive Agents; Depression; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Tolerance; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Precision Medicine; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes

2012
A general approach for sample size calculation for the three-arm 'gold standard' non-inferiority design.
    Statistics in medicine, 2012, Dec-10, Volume: 31, Issue:28

    Topics: Antidepressive Agents; Citalopram; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Likelihood Functions; Multiple Sclerosis, Relapsing-Remitting; Placebos; Poisson Distribution; Randomized Controlled Trials as Topic; Research Design; Sample Size; Therapeutic Equivalency; Thiophenes; Time Factors; Treatment Outcome

2012
Serotonin-norepinephrine reuptake inhibitor treatment for tinnitus and depression.
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Aged; Depressive Disorder, Major; Duloxetine Hydrochloride; Follow-Up Studies; Humans; Male; Selective Serotonin Reuptake Inhibitors; Thiophenes; Tinnitus; Treatment Outcome

2012
Might different cytokine trends in depressed patients receiving duloxetine indicate differential biological backgrounds.
    Journal of affective disorders, 2013, Mar-05, Volume: 145, Issue:3

    Topics: Adult; Antidepressive Agents; Biomarkers; Case-Control Studies; Cytokines; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Interferon-gamma; Interleukin-10; Interleukin-12; Interleukin-1beta; Interleukin-2; Interleukin-4; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes; Treatment Outcome; Tumor Necrosis Factor-alpha

2013
Increases in amplitude of low-frequency fluctuations in left fronto-parietal area after duloxetine therapy in first-episode, drug-naïve, major depressive disorder with panic disorder patients.
    The Journal of neuropsychiatry and clinical neurosciences, 2012,Summer, Volume: 24, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Frontal Lobe; Functional Laterality; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Oxygen; Panic Disorder; Parietal Lobe; Thiophenes; Young Adult

2012
A case of severe hyponatremia induced by duloxetine and ziprasidone.
    Chinese medical journal, 2012, Volume: 125, Issue:20

    Topics: Antidepressive Agents; Antipsychotic Agents; Creatine Kinase; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Hyponatremia; Middle Aged; Piperazines; Thiazoles; Thiophenes

2012
Antidepressant use in underweight older adults.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2012, Volume: 27, Issue:12

    Topics: Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Appetite; Body Mass Index; Body Weight; Depressive Disorder, Major; Duloxetine Hydrochloride; Hospitals, University; Humans; Inservice Training; Mianserin; Mirtazapine; Practice Patterns, Physicians'; Retrospective Studies; Thinness; Thiophenes

2012
Interactive medical case. A patient found unresponsive.
    The New England journal of medicine, 2012, Dec-13, Volume: 367, Issue:24

    Topics: Adolescent; Anorexia Nervosa; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Diagnosis, Differential; Dibenzothiazepines; Duloxetine Hydrochloride; Electrocardiography; Female; Humans; Hypokalemia; Quetiapine Fumarate; Suicide, Attempted; Thiophenes; Unconsciousness

2012
Association of candidate gene polymorphisms with diastolic blood pressure change in patients treated with duloxetine.
    Psychiatry research, 2013, Apr-30, Volume: 206, Issue:2-3

    Topics: Adrenergic Uptake Inhibitors; Blood Pressure; Catechol O-Methyltransferase; Depressive Disorder, Major; Diastole; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Norepinephrine Plasma Membrane Transport Proteins; Pain; Polymorphism, Single Nucleotide; Receptors, Adrenergic, beta-2; Receptors, Dopamine; Receptors, Serotonin; Thiophenes

2013
Antidepressant-selective gynecomastia.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:1

    Topics: Aged; Amlodipine; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluorobenzenes; Gynecomastia; Humans; Male; Pyrimidines; Rosuvastatin Calcium; Sertraline; Sulfonamides; Thiophenes

2013
Duloxetine for the treatment of major depressive disorder.
    Psychopharmacology bulletin, 2002,Autumn, Volume: 36, Issue:4

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Thiophenes; Treatment Outcome

2002
A word of caution about the implied role for duloxetine in pain management.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:10

    Topics: Antidepressive Agents; Comorbidity; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Somatoform Disorders; Thiophenes; Treatment Outcome

2003
[Physical recovery is part of remission].
    Krankenpflege Journal, 2004, Volume: 42, Issue:3-4

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Nursing Assessment; Personality Inventory; Selective Serotonin Reuptake Inhibitors; Somatoform Disorders; Thiophenes; Treatment Outcome

2004
The efficacy of duloxetine: a comprehensive summary of results from MMRM and LOCF_ANCOVA in eight clinical trials.
    BMC psychiatry, 2004, Sep-08, Volume: 4

    Topics: Analysis of Variance; Antidepressive Agents; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Data Interpretation, Statistical; Depressive Disorder, Major; Drug Approval; Duloxetine Hydrochloride; Endpoint Determination; Humans; Longitudinal Studies; Models, Statistical; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Thiophenes; Treatment Outcome

2004
Duloxetine hydrochloride.
    Nature reviews. Drug discovery, 2004, Volume: 3, Issue:11

    Topics: Animals; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Marketing; Molecular Structure; Selective Serotonin Reuptake Inhibitors; Thiophenes

2004
[Duloxetine receives positive recommendation by the Scientific Committee of EMEA for treatment of depression].
    Krankenpflege Journal, 2004, Volume: 42, Issue:7-10

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder, Major; Diabetic Neuropathies; Drug Approval; Duloxetine Hydrochloride; Europe; Humans; Pharmacy and Therapeutics Committee; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress

2004
Duloxetine for the treatment of major depressive disorder in older patients.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005, Volume: 13, Issue:3

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2005
Duloxetine fights major depressive disorder.
    The Nurse practitioner, 2005, Volume: 30, Issue:3

    Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Thiophenes

2005
Duloexetine (Cymbalta) for treatment of major depressive disorder.
    American family physician, 2005, Sep-15, Volume: 72, Issue:6

    Topics: Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2005
An open-label study of duloxetine for the treatment of major depressive disorder: comparison of switching versus initiating treatment approaches.
    Journal of clinical psychopharmacology, 2005, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Citalopram; Cyclohexanols; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Fluvoxamine; Humans; Male; Middle Aged; Paroxetine; Sertraline; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2005
[Brief case report. Duloxetine in Cotard syndrome].
    Psychiatrische Praxis, 2005, Volume: 32, Issue:8

    Topics: Affective Disorders, Psychotic; Aged; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Citalopram; Delusions; Depersonalization; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Long-Term Care; Olanzapine; Risperidone; Syndrome; Thiophenes

2005
The combination of duloxetine and bupropion for treatment-resistant major depressive disorder.
    Depression and anxiety, 2006, Volume: 23, Issue:3

    Topics: Adult; Antidepressive Agents; Bupropion; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Retrospective Studies; Thiophenes; Treatment Outcome

2006
Biological perspectives. Serotonin and norepinephrine reuptake inhibitors (SNRIs): venlafaxine and duloxetine.
    Perspectives in psychiatric care, 2006, Volume: 42, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Adult; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride

2006
Duloxetine treatment of major depressive episodes in the course of psychotic disorders.
    Pharmacopsychiatry, 2006, Volume: 39, Issue:3

    Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Personality Inventory; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Thiophenes; Treatment Outcome

2006
Duloxetine for childhood depression with pain and dissociative symptoms.
    European child & adolescent psychiatry, 2006, Volume: 15, Issue:8

    Topics: Antidepressive Agents; Benzodiazepines; Child; Depressive Disorder, Major; Dissociative Disorders; Duloxetine Hydrochloride; Female; Humans; Olanzapine; Pain; Thiophenes

2006
Combined use of ECT with duloxetine and olanzapine: a case report.
    The journal of ECT, 2006, Volume: 22, Issue:2

    Topics: Adult; Benzodiazepines; Combined Modality Therapy; Depressive Disorder, Major; Duloxetine Hydrochloride; Electroconvulsive Therapy; Female; Humans; Olanzapine; Selective Serotonin Reuptake Inhibitors; Stress Disorders, Post-Traumatic; Thiophenes

2006
Immediate switching from moclobemide to duloxetine may induce serotonin syndrome.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:11

    Topics: Antidepressive Agents; Depressive Disorder, Major; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Thiophenes

2006
Duloxetine and hyponatremia: a report of 5 cases.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:1

    Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Hyponatremia; Male; Middle Aged; Thiophenes

2007
A retrospective pooled analysis of duloxetine safety in 23,983 subjects.
    Current medical research and opinion, 2007, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anxiety Disorders; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Prevalence; Retrospective Studies; Thiophenes; United States; Urinary Incontinence, Stress

2007
Duloxetine treatment of pediatric chronic pain and co-morbid major depressive disorder.
    Journal of child and adolescent psychopharmacology, 2007, Volume: 17, Issue:1

    Topics: Abdominal Pain; Adolescent; Antidepressive Agents; Chronic Disease; Comorbidity; Crohn Disease; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Low Back Pain; Pain; Sick Role; Thiophenes

2007
Simple options for improving signal detection in antidepressant clinical trials.
    Psychopharmacology bulletin, 2007, Volume: 40, Issue:2

    Topics: Antidepressive Agents; Citalopram; Clinical Trials as Topic; Databases, Factual; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Fluoxetine; Likelihood Functions; Models, Statistical; Paroxetine; Personality Inventory; Placebo Effect; Psychometrics; Reproducibility of Results; Research Design; Signal Detection, Psychological; Thiophenes; Treatment Outcome

2007
Manic switching in patients receiving duloxetine.
    The American journal of psychiatry, 2007, Volume: 164, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Adult; Bipolar Disorder; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychotic Disorders; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes

2007
Duloxetine--three birds with one stone?
    International journal of clinical practice, 2007, Volume: 61, Issue:8

    Topics: Antidepressive Agents; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress

2007
Successful duloxetine use to prevent venlafaxine withdrawal symptoms.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Feb-15, Volume: 32, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Adult; Cyclohexanols; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Neurotransmitter Uptake Inhibitors; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome; Thiophenes; Venlafaxine Hydrochloride

2008
Duloxetine treatment of Premenstrual Dysphoric Disorder: case reports.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Feb-15, Volume: 32, Issue:2

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Neurotransmitter Uptake Inhibitors; Premenstrual Syndrome; Selective Serotonin Reuptake Inhibitors; Thiophenes

2008
Suicidal ideation associated with duloxetine use: a case series.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:1

    Topics: Adult; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Risk Factors; Selective Serotonin Reuptake Inhibitors; Suicide; Thinking; Thiophenes

2008
Successful treatment of nicotine withdrawal with duloxetine: a case report.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:1

    Topics: Adult; Alcohol Drinking; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Smoking; Substance Withdrawal Syndrome; Thiophenes; Tobacco Use Disorder

2008
Duloxetine-induced cutaneous adverse reaction.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Depressive Disorder, Major; Duloxetine Hydrochloride; Exanthema; Female; Humans; Middle Aged; Pruritus; Selective Serotonin Reuptake Inhibitors; Thiophenes

2008
Combining mirtazapine and duloxetine in treatment-resistant depression improves outcomes and sexual function.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Adult; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Histamine H1 Antagonists; Humans; Male; Mianserin; Mirtazapine; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunctions, Psychological; Thiophenes; Treatment Outcome

2008
Response to duloxetine in a depressed, treatment-resistant adolescent female.
    Journal of child and adolescent psychopharmacology, 2007, Volume: 17, Issue:6

    Topics: Adolescent; Antidepressive Agents; Combined Modality Therapy; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Phototherapy; Seasons; Thiophenes; Treatment Outcome

2007
A Markov cost-utility analysis of escitalopram and duloxetine for the treatment of major depressive disorder.
    Current medical research and opinion, 2008, Volume: 24, Issue:4

    Topics: Antidepressive Agents; Citalopram; Cost-Benefit Analysis; Depressive Disorder, Major; Drug Costs; Duloxetine Hydrochloride; Humans; Markov Chains; Models, Economic; Monte Carlo Method; Quality-Adjusted Life Years; Thiophenes; Treatment Outcome; United States

2008