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thiophenes and Degenerative Diseases, Central Nervous System

thiophenes has been researched along with Degenerative Diseases, Central Nervous System in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's5 (41.67)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Busra Azizoglu, Z; Canatan, H; Eken, A; Zehra Okus, F1
Choe, HK; Choe, Y; Choi, JW; Choi, M; Jang, S; Kim, D; Kim, J; Kim, K; Moon, C; Park, I; Park, SH; Sun, W1
Ahmed, HA; Devlin, P; Ishrat, T; Ismael, S; Liao, FF; McDonald, MP; Salman, M1
Hort, J; Klimova, B; Kuca, K; Nepovimova, E; Novotny, M; Oleksak, P; Patocka, J; Pavlik, J; Valis, M1
Abate, C; Capparelli, E; Colabufo, NA; Contino, M; Spinelli, F1
Jiang, D; Koong, AC; Niwa, M1
Goedert, M; Jucker, M; Klingstedt, T; Mahler, J; Nilsson, KP; Nyström, S; Shirani, H; Wegenast-Braun, BM1
Hekmatimoghaddam, S; Pourrajab, F; Zare-Khormizi, MR1
Aguzzi, A; Aslund, A; Bolmont, T; Dickstein, DL; Gandy, S; Glimsdal, E; Grathwohl, S; Hammarström, P; Heppner, FL; Hof, PR; Holtzman, DM; Jucker, M; Klingstedt, T; Konradsson, P; Lindgren, M; Nilsson, KP; Prokop, S; Sigurdson, CJ1
Cho, YS; Kwon, HJ1
Delgado, PL1
Gharibzadeh, S; Hoseini, SS; Mahdavi, S1

Reviews

6 review(s) available for thiophenes and Degenerative Diseases, Central Nervous System

ArticleYear
Neuropharmacology of Cevimeline and Muscarinic Drugs-Focus on Cognition and Neurodegeneration.
    International journal of molecular sciences, 2021, Aug-18, Volume: 22, Issue:16

    Topics: Animals; Cognition Disorders; Humans; Muscarinic Agonists; Neurodegenerative Diseases; Neuropharmacology; Pharmaceutical Preparations; Quinuclidines; Thiophenes

2021
Perspectives of Cannabinoid Type 2 Receptor (CB2R) Ligands in Neurodegenerative Disorders: Structure-Affinity Relationship (SAfiR) and Structure-Activity Relationship (SAR) Studies.
    Journal of medicinal chemistry, 2017, 12-28, Volume: 60, Issue:24

    Topics: Humans; Indoles; Ligands; Molecular Docking Simulation; Neurodegenerative Diseases; Neuroprotective Agents; Positron-Emission Tomography; Purines; Quinolones; Receptor, Cannabinoid, CB2; Structure-Activity Relationship; Thiophenes

2017
Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases.
    Seminars in cancer biology, 2015, Volume: 33

    Topics: Aldehydes; Animals; Apoptosis; Cell Survival; Coumarins; Disease Models, Animal; Disease Progression; DNA-Binding Proteins; Drug Design; Drug Discovery; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Endoribonucleases; Homeostasis; Humans; Mice; Neoplasms; Neurodegenerative Diseases; Prognosis; Protein Folding; Protein Serine-Threonine Kinases; Quercetin; Regulatory Factor X Transcription Factors; Signal Transduction; Sulfonamides; Thiophenes; Toyocamycin; Transcription Factors; Unfolded Protein Response; X-Box Binding Protein 1

2015
Underlying mechanisms and chemical/biochemical therapeutic approaches to ameliorate protein misfolding neurodegenerative diseases.
    BioFactors (Oxford, England), 2017, Volume: 43, Issue:6

    Topics: Amyloidogenic Proteins; Animals; Chalcones; Endoplasmic Reticulum; Gene Expression Regulation; Heat-Shock Response; Humans; Hydrazones; Molecular Chaperones; Neurodegenerative Diseases; Neuroprotective Agents; Protein Aggregation, Pathological; Protein Folding; Proteostasis; Proteostasis Deficiencies; Pyrimidinones; Thiophenes; Unfolded Protein Response

2017
Control of autophagy with small molecules.
    Archives of pharmacal research, 2010, Volume: 33, Issue:12

    Topics: Alzheimer Disease; Autophagy; Cell Death; Humans; Neurodegenerative Diseases; Parkinson Disease; Proteins; Pyrimidinones; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Thiophenes

2010
Common pathways of depression and pain.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 12

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Brain; Chronic Disease; Cyclohexanols; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Norepinephrine; Pain; Recurrence; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Venlafaxine Hydrochloride

2004

Other Studies

6 other study(ies) available for thiophenes and Degenerative Diseases, Central Nervous System

ArticleYear
S1P analogues SEW2871, BAF312 and FTY720 affect human Th17 and Treg generation ex vivo.
    International immunopharmacology, 2022, Volume: 107

    Topics: Animals; Azetidines; Benzyl Compounds; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Interleukin-23; Lysophospholipids; Mice; Neurodegenerative Diseases; Oxadiazoles; Propylene Glycols; Receptors, Lysosphingolipid; Sphingosine; T-Lymphocytes, Regulatory; Th17 Cells; Thiophenes

2022
Pharmacological Rescue with SR8278, a Circadian Nuclear Receptor REV-ERBα Antagonist as a Therapy for Mood Disorders in Parkinson's Disease.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2022, Volume: 19, Issue:2

    Topics: Animals; Humans; Isoquinolines; Mice; Mood Disorders; Neurodegenerative Diseases; Nuclear Receptor Subfamily 1, Group D, Member 1; Oxidopamine; Parkinson Disease; Quality of Life; Thiophenes; Tyrosine 3-Monooxygenase

2022
Direct AT2R Stimulation Slows Post-stroke Cognitive Decline in the 5XFAD Alzheimer's Disease Mice.
    Molecular neurobiology, 2022, Volume: 59, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Disease Models, Animal; Humans; Imidazoles; Mice; Mice, Transgenic; Neurodegenerative Diseases; Receptor, Angiotensin, Type 2; Stroke; Sulfonamides; Thiophenes

2022
Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic Aggregates.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2015, Jun-15, Volume: 21, Issue:25

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anions; Brain; Fluorescent Dyes; Humans; Ligands; Luminescent Agents; Mice; Molecular Probes; Neurodegenerative Diseases; Proteins; Thiophenes

2015
Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses.
    ACS chemical biology, 2009, Aug-21, Volume: 4, Issue:8

    Topics: Acetates; Amyloid beta-Peptides; Amyloidosis; Animals; Brain Diseases; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Molecular Structure; Neurodegenerative Diseases; Thiophenes

2009
Oltipraz may be useful in the prevention or treatment of Alzheimer's disease.
    Medical hypotheses, 2007, Volume: 68, Issue:4

    Topics: Alzheimer Disease; Animals; Humans; Mice; Neurodegenerative Diseases; Oxidative Stress; Pyrazines; Schistosomicides; Thiones; Thiophenes

2007