thiophenes has been researched along with Cognitive Dysfunction in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 5 (35.71) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, YD; Li, WJ; Lu, J; Lu, Y; Meng, XR; Nie, RF; Ou-Yang, XN; Shen, X; Xu, R; Yan, QY; Yang, JZ; Zhang, YN; Zhao, T; Zhu, DY | 1 |
| Ahmed, HA; Devlin, P; Ishrat, T; Ismael, S; Liao, FF; McDonald, MP; Salman, M | 1 |
| Althomali, W; Baban, B; Dong, G; Eldahshan, W; Ergul, A; Fagan, SC; Filosa, J; Jackson, L; Johnson, MH; Sayed, MA | 1 |
| Beck, WD; Blake, DT; Callahan, PM; Plagenhoef, MR; Terry, AV | 1 |
| Huang, G; Li, W; Liu, H; Luo, S; Lv, X; Wang, Y; Zhou, D | 1 |
| Ahmed, HA; Arbab, AS; Bunting, KM; Ergul, A; Fagan, SC; Ishrat, T; Patel, A; Pillai, B; Vazdarjanova, A; Waller, JL | 1 |
| Ahmed, HA; Eldahshan, W; Ergul, A; Fagan, SC; Fouda, AY; Ishrat, T; Pillai, B; Sayed, MA; Waller, JL | 1 |
| Ahmed, HA; Bunting, KM; Ergul, A; Fagan, SC; Ishrat, T; Pillai, B; Vazdarjanova, A; Waller, JL | 1 |
| Burris, TP; Farr, SA; Kermath, BA; Morley, JE; Musiek, ES; Niehoff, M; Roby, DA; Ruiz, F; Voorhees, JR; Zhang, J | 1 |
| Begley, A; Butters, MA; Koenig, AM; Ogbagaber, S; Reynolds, CF; Wahed, AS | 1 |
| Blazquez-Llorca, L; Brandt Elvang, A; Filser, S; Herms, J; Jung, CK; Masana, M; Müller, MB; Ovsepian, SV; Volbracht, C | 1 |
| Bednar, MM; Cahill, J; D'Souza, DC; DeMartinis, N; Gaudreault, F; Gupta, S; Huguenel, B; Mancuso, J; Ranganathan, M; Shaffer, CL; Sherif, MA; Zumpano, L | 1 |
| Gallagher, M; Koh, MT; Rosenzweig-Lipson, S | 1 |
1 trial(s) available for thiophenes and Cognitive Dysfunction
| Article | Year |
|---|---|
RAS modulation prevents progressive cognitive impairment after experimental stroke: a randomized, blinded preclinical trial.
Topics: Amyloid beta-Peptides; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Hypoxia; Cells, Cultured; Cognitive Dysfunction; Disease Models, Animal; Double-Blind Method; Endothelial Cells; Epoetin Alfa; Hippocampus; Humans; Infarction, Middle Cerebral Artery; Locomotion; Male; Peptide Fragments; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sensory Gating; Sulfonamides; Tetrazoles; Thiophenes | 2018 |
13 other study(ies) available for thiophenes and Cognitive Dysfunction
| Article | Year |
|---|---|
FX5, a non-steroidal glucocorticoid receptor antagonist, ameliorates diabetic cognitive impairment in mice.
Topics: Animals; Brain-Derived Neurotrophic Factor; Caspases; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3 beta; Hippocampus; Lipopolysaccharides; Maze Learning; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptors, Glucocorticoid; Sulfonamides; Thiophenes | 2022 |
Direct AT2R Stimulation Slows Post-stroke Cognitive Decline in the 5XFAD Alzheimer's Disease Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Disease Models, Animal; Humans; Imidazoles; Mice; Mice, Transgenic; Neurodegenerative Diseases; Receptor, Angiotensin, Type 2; Stroke; Sulfonamides; Thiophenes | 2022 |
Delayed Administration of Angiotensin II Type 2 Receptor (AT2R) Agonist Compound 21 Prevents the Development of Post-stroke Cognitive Impairment in Diabetes Through the Modulation of Microglia Polarization.
Topics: Animals; Cell Polarity; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Diet, High-Fat; Imidazoles; Male; Microglia; Rats, Wistar; Receptor, Angiotensin, Type 2; Streptozocin; Stroke; Sulfonamides; Thiophenes | 2020 |
Aged rhesus monkeys: Cognitive performance categorizations and preclinical drug testing.
Topics: Aging; Animals; Cognition; Cognitive Dysfunction; Drug Evaluation, Preclinical; Female; Macaca mulatta; Male; Memory, Short-Term; Nootropic Agents; Quinuclidines; Thiophenes | 2021 |
Folic acid alleviates age-related cognitive decline and inhibits apoptosis of neurocytes in senescence-accelerated mouse prone 8: deoxythymidine triphosphate biosynthesis as a potential mechanism.
Topics: Aging; Animals; Apoptosis; Brain; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Male; Memory; Mice; Morris Water Maze Test; Neurons; Quinazolines; Telomere Shortening; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Uracil | 2021 |
Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cells, Cultured; Cognitive Dysfunction; Corpus Striatum; Epigenomics; Gene Expression; Gene Expression Profiling; Gene Knockdown Techniques; Histones; Humans; Huntingtin Protein; Huntington Disease; Induced Pluripotent Stem Cells; Isoxazoles; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurogenesis; Neurons; Peptides; Signal Transduction; Thiophenes | 2017 |
Role of angiotensin system modulation on progression of cognitive impairment and brain MRI changes in aged hypertensive animals - A randomized double- blind pre-clinical study.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Brain; Cognitive Dysfunction; Disease Progression; Double-Blind Method; Drug Evaluation, Preclinical; Hypertension; Magnetic Resonance Imaging; Male; Neuroprotective Agents; Nootropic Agents; Organ Size; Random Allocation; Rats, Inbred SHR; Renin-Angiotensin System; Sulfonamides; Tetrazoles; Thiophenes | 2018 |
Angiotensin receptor (AT2R) agonist C21 prevents cognitive decline after permanent stroke in aged animals-A randomized double- blind pre-clinical study.
Topics: Administration, Oral; Aging; Animals; Body Weight; Cognitive Dysfunction; Disease Models, Animal; Double-Blind Method; Drug Evaluation, Preclinical; Male; Motor Activity; Nootropic Agents; Random Allocation; Rats, Wistar; Receptor, Angiotensin, Type 2; Recovery of Function; Stroke; Sulfonamides; Thiophenes; Time Factors | 2019 |
Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Disease Models, Animal; Disks Large Homolog 4 Protein; Hippocampus; Male; Mice; Nuclear Receptor Subfamily 1, Group D, Member 1; Peptide Fragments; Pyrrolidines; Thiophenes | 2019 |
Response to antidepressant medications in late-life depression across the spectrum of cognitive functioning.
Topics: Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Aripiprazole; Citalopram; Cognitive Dysfunction; Cyclohexanols; Dementia; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Piperazines; Quinolones; Randomized Controlled Trials as Topic; Recurrence; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Venlafaxine Hydrochloride | 2014 |
Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Cognition; Cognitive Dysfunction; Dendritic Spines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptide Fragments; Pyramidal Cells; Pyrimidines; Pyrimidinones; Synaptic Potentials; Thiazines; Thiophenes; Time Factors | 2015 |
Attenuation of ketamine-induced impairment in verbal learning and memory in healthy volunteers by the AMPA receptor potentiator PF-04958242.
Topics: Adult; Cognitive Dysfunction; Double-Blind Method; Female; Healthy Volunteers; Humans; Ketamine; Male; Memory Disorders; Memory, Short-Term; Mental Recall; Neuronal Plasticity; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spatial Memory; Sulfonamides; Thiophenes; Verbal Learning | 2017 |
Selective GABA(A) α5 positive allosteric modulators improve cognitive function in aged rats with memory impairment.
Topics: Aging; Allosteric Regulation; Animals; Carboxylic Acids; Cognition; Cognitive Dysfunction; GABA-A Receptor Agonists; Hippocampus; Infusions, Intraventricular; Injections, Intraperitoneal; Male; Memory; Memory Disorders; Molecular Targeted Therapy; Neurons; Nootropic Agents; Pyridazines; Rats; Rats, Long-Evans; Receptors, GABA-A; Specific Pathogen-Free Organisms; Synaptic Transmission; Thiazoles; Thiophenes | 2013 |