thiophenes has been researched along with Cardiomegaly in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 9 (45.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carletti, R; Castoldi, G; di Gioia, CRT; Ippolito, S; Pelucchi, S; Stella, A; Zatti, G; Zerbini, G | 1 |
| Andrés, A; Fernández, A; Gallardo, N; López, V; Mazuecos, L; Mora, C; Pintado, C; Rubio, B | 1 |
| Bahtiar, A; Fujio, Y; Kametani, Y; Kobayashi, A; Maeda, M; Matsumoto, K; Miyake, Y; Mori, S; Obana, M; Tanaka, S; Tomimatsu, M; Wahyuni, T; Yamamoto, A | 1 |
| Fujiwara, S; Matsumoto, H; Miyagi, H; Nakamura, N; Ohta, T; Shiga, Y; Tsuzuki, M | 1 |
| Balligand, JL; Beauloye, C; Bertrand, L; Bouchard, B; Bultot, L; Daskalopoulos, EP; Demeulder, B; Des Rosiers, C; Dontaine, J; Dubois-Deruy, E; Esfahani, H; Gauthier, C; Gélinas, R; Ginion, A; Horman, S; Lauzier, B; Mailleux, F; Olson, AK; Sakamoto, K; Vanoverschelde, JL; Viollet, B | 1 |
| Chang, WT; Chen, ZC; Cheng, JT; Cheng, KC; Cheng, YZ; Li, Y | 1 |
| Carletti, R; Castoldi, G; di Gioia, CRT; Manzoni, G; Perseghin, G; Roma, F; Stella, A; Zerbini, G | 1 |
| Dopona, EPB; Furukawa, LNS; Heimann, JC; Oliveira, IB; Rocha, VF | 1 |
| Drummer, OH; Gerostamoulos, D; Pilgrim, JL | 1 |
| Lee, BH; Lee, JH; Lim, CJ; Oh, KS; Park, BK; Seo, HW; Yi, KY | 1 |
| Caruso-Neves, C; Costa, DG; da Silva, JS; de Lacerda Barreiro, EJ; Fraga, CA; Kümmerle, AE; Landgraf, SS; Sudo, RT; Zapata-Sudo, G | 1 |
| Al-Attas, OS; Arya, DS; Bharti, S; Chauhan, SS; Hussain, T; Singh, R | 1 |
| Abassi, Z; Abbasi, A; Golomb, E; Hochberg, I; Hoffman, A; Karram, T; Keidar, S; Winaver, J | 1 |
| Henry, SP; Knowlton, P; Loewen, G; Low, JE; Mertz, TE; Metz, AL; Olszewski, BJ; Robertson, DG; Schroeder, RL; Sommers, CS | 1 |
| Abassi, Z; Brodsky, S; Feuerstein, GZ; Gurbanov, K; Hoffman, A; Ruffolo, RR; Winaver, J | 1 |
| Block, N; Brock, TA; Chen, SJ; Chen, YF; Dixon, RA; Munsch, CL; Sherwood, SJ; Tilton, RG; Wu, C | 1 |
| Barone, FC; Brooks, DP; Campbell, WG; Chandra, S; Coatney, RW; Contino, LC; Nelson, AH; Ohlstein, EH; Sarkar, SK; Willette, RN | 1 |
| Betocchi, S; Condorelli, M; De Luca, N; Filardi, PP; Raponi, M; Ricciardelli, B; Rosiello, G; Trimarco, B | 1 |
| Condorelli, G; Condorelli, M; DeLuca, N; Marchegiano, R; Raponi, M; Ricciardelli, B; Rosiello, G; Trimarco, B | 1 |
| Condorelli, M; Cuocolo, A; de Luca, N; Lembo, G; Ricciardelli, B; Trimarco, B; Volpe, M | 1 |
20 other study(ies) available for thiophenes and Cardiomegaly
| Article | Year |
|---|---|
Angiotensin Type 2 and Mas Receptor Activation Prevents Myocardial Fibrosis and Hypertrophy through the Reduction of Inflammatory Cell Infiltration and Local Sympathetic Activity in Angiotensin II-Dependent Hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Hypertension; Imidazoles; Injections, Intraperitoneal; Losartan; Male; Peptide Fragments; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; Tyrosine 3-Monooxygenase | 2021 |
The nutrient sensing pathways FoxO1/3 and mTOR in the heart are coordinately regulated by central leptin through PPARβ/δ. Implications in cardiac remodeling.
Topics: Animals; Cardiomegaly; Forkhead Box Protein O1; Forkhead Box Protein O3; Heart; Leptin; Male; Myocardium; PPAR delta; PPAR-beta; Rats; Rats, Wistar; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction; Sulfones; Thiophenes; TOR Serine-Threonine Kinases; Ventricular Remodeling | 2021 |
Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Disease Models, Animal; Docosahexaenoic Acids; Gene Expression Regulation; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocytes, Cardiac; Nuclear Receptor Subfamily 1, Group F, Member 1; Paracrine Communication; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Rats; Ribonucleosides; Signal Transduction; Sulfonamides; Thiophenes; Wortmannin | 2021 |
Carbonic Anhydrase Inhibitors Induce Developmental Toxicity During Zebrafish Embryogenesis, Especially in the Inner Ear.
Topics: Acetazolamide; Animal Fins; Animals; Apoptosis; Calcium; Carbonic Anhydrase Inhibitors; Cardiomegaly; Ear, Inner; Embryo, Nonmammalian; Embryonic Development; Ethoxzolamide; Hair Cells, Auditory; Otolithic Membrane; Sulfonamides; Swimming; Thiophenes; Zebrafish | 2017 |
AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation.
Topics: Acetylglucosamine; Acylation; AMP-Activated Protein Kinases; Animals; Animals, Newborn; Azaserine; Azo Compounds; Biphenyl Compounds; Cardiomegaly; Enzyme Activation; Enzyme Activators; Gene Expression Regulation; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Glycosylation; Heart Ventricles; Male; Mice; Mice, Knockout; Myocardium; Myocytes, Cardiac; Nitrogenous Group Transferases; Norleucine; Phosphorylation; Primary Cell Culture; Pyrones; Rats; Rats, Wistar; Signal Transduction; Thiophenes; Troponin T | 2018 |
GW0742 activates peroxisome proliferator-activated receptor δ to reduce free radicals and alleviate cardiac hypertrophy induced by hyperglycemia in cultured H9c2 cells.
Topics: Animals; Blotting, Western; Calcium; Cardiomegaly; Cell Line; Free Radicals; Hyperglycemia; Rats; Reactive Oxygen Species; Sulfones; Thiazoles; Thiophenes | 2018 |
Activation of angiotensin type 2 (AT2) receptors prevents myocardial hypertrophy in Zucker diabetic fatty rats.
Topics: Animals; Blood Glucose; Cardiomegaly; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Losartan; Male; Obesity; Oxidative Stress; Rats; Rats, Zucker; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes | 2019 |
Myocardial hypertrophy induced by high salt consumption is prevented by angiotensin II AT2 receptor agonist.
Topics: Animals; Blood Pressure; Cardiomegaly; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Hypertension; Male; Myocytes, Cardiac; Rats, Wistar; Receptor, Angiotensin, Type 2; Signal Transduction; Sodium Chloride, Dietary; Sulfonamides; Thiophenes; Ventricular Remodeling; Weight Gain | 2019 |
The prevalence of duloxetine in medico-legal death investigations in Victoria, Australia (2009-2012).
Topics: Adult; Aged; Antidepressive Agents; Australia; Cardiomegaly; Cause of Death; Chromatography, Liquid; Cohort Studies; Coronary Artery Disease; Coroners and Medical Examiners; Drug Interactions; Duloxetine Hydrochloride; Female; Forensic Toxicology; Humans; Male; Middle Aged; Pharmaceutical Preparations; Prevalence; Pulmonary Edema; Tandem Mass Spectrometry; Thiophenes | 2014 |
A novel urotensin II receptor antagonist, KR-36996, improved cardiac function and attenuated cardiac hypertrophy in experimental heart failure.
Topics: Animals; Body Weight; Cardiomegaly; Cell Line; Chronic Disease; Electrocardiography; Heart; Heart Failure; Hemodynamics; Humans; Male; Mice; Myocardium; Organ Size; Piperidines; Pressure; Rats; Receptors, G-Protein-Coupled; Substrate Specificity; Thiophenes | 2017 |
LASSBio-294, A compound with inotropic and lusitropic activity, decreases cardiac remodeling and improves Ca²(+) influx into sarcoplasmic reticulum after myocardial infarction.
Topics: Animals; Blood Pressure; Calcium; Cardiomegaly; Cardiotonic Agents; Disease Models, Animal; Hydrazones; Male; Myocardial Contraction; Myocardial Infarction; Myocytes, Cardiac; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thiophenes; Ventricular Remodeling | 2010 |
Phosphorylation of Akt/GSK-3β/eNOS amplifies 5-HT2B receptor blockade mediated anti-hypertrophic effect in rats.
Topics: Animals; Cardiomegaly; Drug Evaluation, Preclinical; Drug Synergism; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Isoproterenol; Male; Maleimides; Myocardium; Nitric Oxide Synthase Type III; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Thiophenes | 2012 |
Effects of spironolactone and eprosartan on cardiac remodeling and angiotensin-converting enzyme isoforms in rats with experimental heart failure.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Arteriovenous Fistula; Carboxypeptidases; Cardiomegaly; Disease Models, Animal; Heart Failure; Imidazoles; Male; Mineralocorticoid Receptor Antagonists; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Spironolactone; Thiophenes; Ventricular Remodeling | 2005 |
Cardiac hypertrophy in rats after intravenous administration of CI-959, a novel antiinflammatory compound: morphologic features and pharmacokinetic and pharmacodynamic mechanisms.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cardiomegaly; Catecholamines; Cells, Cultured; Creatine Kinase; Disease Models, Animal; Glycogen; Heart; Heart Rate; Infusion Pumps, Implantable; Infusions, Intravenous; L-Lactate Dehydrogenase; Microscopy, Electron; Myocardium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tetrazoles; Thiophenes | 1995 |
Effects of eprosartan on renal function and cardiac hypertrophy in rats with experimental heart failure.
Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Heart Failure; Hemodynamics; Imidazoles; Kidney; Male; Rats; Rats, Wistar; Renal Circulation; Sodium; Thiophenes | 1998 |
Attenuation of pulmonary vascular hypertension and cardiac hypertrophy with sitaxsentan sodium, an orally active ET(A) receptor antagonist.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertension, Pulmonary; Hypertrophy; Hypoxia; Isoxazoles; Male; Monocrotaline; Oxygen; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Thiophenes; Vasoconstriction; Weight Gain | 2000 |
Eprosartan reduces cardiac hypertrophy, protects heart and kidney, and prevents early mortality in severely hypertensive stroke-prone rats.
Topics: Acrylates; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Hypertension; Imidazoles; Kidney; Magnetic Resonance Imaging; Male; Myocardium; Natriuresis; Organ Size; Peptide Fragments; Protein Precursors; Proteinuria; Rats; Rats, Inbred SHR; Stroke; Survival Rate; Thiophenes; Ventricular Remodeling | 2001 |
Improvement of diastolic function after reversal of left ventricular hypertrophy induced by long-term antihypertensive treatment with tertatolol.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Cardiomegaly; Echocardiography; Heart Rate; Humans; Hypertension; Myocardial Contraction; Propanolamines; Radionuclide Angiography; Stroke Volume; Thiophenes; Time Factors | 1989 |
Effects of long-term antihypertensive treatment with tertatolol on diastolic function in hypertensive patients with and without left ventricular hypertrophy.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Cardiomegaly; Diastole; Echocardiography, Doppler; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Propanolamines; Thiophenes; Time Factors | 1989 |
Reversal of left ventricular hypertrophy following treatment with beta-blockers: experience with tertatolol.
Topics: Adrenergic beta-Antagonists; Animals; Cardiomegaly; Echocardiography; Humans; Hypertension; Middle Aged; Propanolamines; Thiophenes | 1986 |