thiophenes has been researched along with Carcinoma, Epidermoid in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (11.11) | 18.7374 |
| 1990's | 7 (25.93) | 18.2507 |
| 2000's | 8 (29.63) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Addeo, A; Alborelli, I; Calgua, B; Fernandez, E; Früh, M; Haefliger, S; Holer, L; Jermann, PM; Joerger, M; Mach, N; Mark, M; Mauti, L; Rothschild, SI; Savic-Prince, S; Schneider, M; Waibel, C | 1 |
| Bauer, RJ; Ehrenschwender, M; Hammer, KP; Heimer, S; Jantsch, J; Knoll, G; Neubert, P; Wagner, S | 1 |
| Han, G; Li, W; Li, X; Yang, B | 1 |
| Aguilar-Bonavides, C; Behrens, C; Çeliktas, M; Delgado, O; Dennison, JB; Dhillon, D; Do, KA; Fahrmann, JF; Gazdar, AF; Hanash, SM; Ostrin, EJ; Taguchi, A; Tanaka, I; Tripathi, SC; Villalobos, P; Wang, H | 1 |
| Chen, P; Dong, Z; Hu, T; Li, M; Li, P; Liu, X; Liu, Z; Sha, B; Wang, L; Zhang, J; Zhang, Y | 1 |
| Alves, MV; Fitzgerald, AL; Frederick, MJ; Gadhikar, MA; Myers, JN; Neskey, DM; Osman, AA; Pickering, CR; Sciuto, MR; Zhao, M | 1 |
| Bai, LY; Chiu, CF; Kapuriya, NP; Sargeant, AM; Shieh, TM; Tsai, YC; Weng, JR; Wu, CY | 1 |
| Frederick, M; Johnson, FM; Kalu, NN; Li, L; Mazumdar, T; Myers, JN; Peng, S; Pickering, CR; Sambandam, V; Shen, L; Singh, R; Tong, P; Wang, J; Zhang, M | 1 |
| Chambers, MS; Stinnett, S; Witsell, DL | 1 |
| Avallone, A; Caponigro, F; Comella, G; Comella, P; De Lucia, L; De Rosa, P; De Rosa, V; Rosati, G | 1 |
| Avallone, A; Bruzzese, F; Budillon, A; Caraglia, M; Comella, P; Delrio, P; Di Gennaro, E; Laus, G; Pepe, S | 1 |
| Peters, GJ; Pinedo, HM; Telleman, F; van der Wilt, CL; van Triest, B | 1 |
| Cheson, BD; Phillips, PH; Sorensen, JM | 1 |
| Ara, G; Chen, YN; Coleman, CN; Recht, A; Teicher, BA | 1 |
| Azrak, RG; Cao, S; Guo, B; Rustum, YM; Tóth, K; Yin, MB | 1 |
| Atarshi, Y; Balkir, L; Gastman, BR; Rabinowich, H; Reichert, TE; Saito, T; Whiteside, TL | 1 |
| Avallone, A; Blackie, R; Budillon, A; Caponigro, F; Cartenì, G; Casaretti, R; Catalano, G; Comella, G; Comella, P; De Lucia, L; De Vita, F; Gravina, A; McLeod, H; Morsman, J | 1 |
| Azrak, RG; Cao, S; Guo, B; Rustum, YM; Tóth, K | 1 |
| Clarke, SJ; Dalley, D; Davidson, YE; Green, M; Mitchell, PL; Olver, I; Rischin, D; Zalcberg, J | 1 |
| Avallone, A; Budillon, A; Caponigro, F; Comella, G; Comella, P; De Rosa, V; Di Gennaro, E; Ionna, F; Manzione, L; Mozzillo, N; Rivellini, F | 1 |
| Baatenburg de Jong, RJ; Keizer, HJ; ten Bokkel Huinink, D; Tesselaar, ME; Verschuur, HP | 1 |
| Ala-Aho, R; Baker, AH; Johansson, N; Kähäri, VM | 1 |
| Chatterjee, M; De Angelis, T; Mulholland, J; Noè, A | 1 |
| Bryan, GT; Cohen, SM; Ertürk, E | 1 |
| Brune, H; Germann, P; Grimmer, G; Timm, J; Wenzel-Hartung, R; Wosniok, W | 1 |
| Albers, R; Biggerstaff, WR; Sugisaka, N | 1 |
| Bell, GR; Shirley, DA | 1 |
7 trial(s) available for thiophenes and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Fibroblast growth factor receptor (FGFR) inhibitor rogaratinib in patients with advanced pretreated squamous-cell non-small cell lung cancer over-expressing FGFR mRNA: The SAKK 19/18 phase II study.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Piperazines; Protein Kinase Inhibitors; Pyrroles; RNA, Messenger; Thiophenes | 2022 |
Effectiveness of cevimeline to improve oral health in patients with postradiation xerostomia.
Topics: Carcinoma, Squamous Cell; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Muscarinic Agonists; Oral Health; Quality of Life; Quinuclidines; Radiotherapy; Salivary Glands; Severity of Illness Index; Thiophenes; Xerostomia | 2012 |
Cisplatin, raltitrexed, levofolinic acid and 5-fluorouracil in locally advanced or metastatic squamous cell carcinoma of the head and neck: a phase II randomized study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Fluorouracil; Head and Neck Neoplasms; Hematologic Diseases; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Neutropenia; Quinazolines; Thiophenes; Treatment Outcome | 2002 |
Phase I and pharmacokinetic study of tomudex combined with 5-fluorouracil plus levofolinic acid in advanced head and neck cancer and colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Middle Aged; Quinazolines; Thiophenes | 1999 |
Open label, multi-centre phase II study of raltitrexed ('Tomudex') in patients with inoperable squamous-cell carcinoma of head and neck.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Quinazolines; Survival Analysis; Thiophenes; Treatment Outcome | 2000 |
Cisplatin, raltitrexed, levofolinic acid and 5-fluorouracil in locally advanced or metastatic squamous cell carcinoma of the head and neck: a phase I-II trial of the Southern Italy Cooperative Oncology Group (SICOG).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Middle Aged; Neutropenia; Quinazolines; Thiophenes; Treatment Outcome | 2000 |
A phase I study of a fixed dose of cisplatin with increasing doses of raltitrexed (Tomudex) in the treatment of patients with locally advanced or metastatic squamous cell carcinoma of the head and neck.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Quinazolines; Thiophenes; Treatment Outcome | 2001 |
20 other study(ies) available for thiophenes and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Hypertonicity counteracts MCL-1 and renders BCL-XL a synthetic lethal target in head and neck cancer.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Synergism; Head and Neck Neoplasms; Humans; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Osmotic Pressure; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; RNA Interference; Thiophenes; Tumor Microenvironment | 2021 |
The EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Proliferation; Dinoprostone; Humans; Mouth Neoplasms; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles; Tumor Cells, Cultured | 2017 |
Role of CPS1 in Cell Growth, Metabolism and Prognosis in LKB1-Inactivated Lung Adenocarcinoma.
Topics: Adenocarcinoma; Aged; AMP-Activated Protein Kinase Kinases; Carbamoyl-Phosphate Synthase (Ammonia); Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Female; Gemcitabine; Gene Knockdown Techniques; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Metabolic Networks and Pathways; Metabolome; Middle Aged; Pemetrexed; Prognosis; Proportional Hazards Models; Protein Serine-Threonine Kinases; Proteome; RNA, Messenger; Signal Transduction; Survival Rate; Thiophenes; Tissue Array Analysis; Urea | 2017 |
Targeting the overexpressed USP7 inhibits esophageal squamous cell carcinoma cell growth by inducing NOXA-mediated apoptosis.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Cell Proliferation; Esophageal Neoplasms; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Prognosis; Proto-Oncogene Proteins c-bcl-2; Thiophenes; Tumor Cells, Cultured; Ubiquitin-Specific Peptidase 7; Xenograft Model Antitumor Assays | 2019 |
Chk1/2 inhibition overcomes the cisplatin resistance of head and neck cancer cells secondary to the loss of functional p53.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Line, Tumor; Cellular Senescence; Checkpoint Kinase 1; Checkpoint Kinase 2; Cisplatin; DNA Damage; Drug Resistance, Neoplasm; Head and Neck Neoplasms; Humans; Mitosis; Molecular Targeted Therapy; Mutation; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Thiophenes; Tumor Suppressor Protein p53; Urea | 2013 |
BX795, a TBK1 inhibitor, exhibits antitumor activity in human oral squamous cell carcinoma through apoptosis induction and mitotic phase arrest.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; I-kappa B Kinase; Mitosis; Mouth Neoplasms; Phosphoproteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Signal Transduction; Thiophenes | 2015 |
Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Dose-Response Relationship, Drug; G2 Phase Cell Cycle Checkpoints; Genotype; Head and Neck Neoplasms; Humans; LIM Domain Proteins; Mice, Nude; Molecular Targeted Therapy; Mutation; Nuclear Proteins; Phenotype; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pteridines; Pyrazoles; Pyrimidines; Pyrimidinones; ras Proteins; RNA Interference; Signal Transduction; Smad4 Protein; Squamous Cell Carcinoma of Head and Neck; Thiophenes; Time Factors; Transfection; Tumor Burden; Urea; Xenograft Model Antitumor Assays | 2017 |
Synergistic antitumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Leucovorin; Quinazolines; Thiophenes | 2007 |
Cross-resistance to thymidylate synthase inhibitors in P-glycoprotein and non-P-glycoprotein cell lines.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Squamous Cell; Cell Cycle; Cell Line; Clone Cells; Doxorubicin; Drug Resistance, Multiple; Fluorodeoxyuridylate; Fluorouracil; Humans; Lung Neoplasms; Quinazolines; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 1994 |
Clinical trials referral resource. Clinical trials with tomudex.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Colorectal Neoplasms; Enzyme Inhibitors; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leukemia; Male; Prostatic Neoplasms; Quinazolines; Thiophenes; Thymidylate Synthase | 1996 |
Interaction of tomudex with radiation in vitro and in vivo.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Lewis Lung; Carcinoma, Squamous Cell; Cell Survival; Combined Modality Therapy; Drug Interactions; Enzyme Inhibitors; Fluorouracil; Head and Neck Neoplasms; HT29 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms; Quinazolines; Radiation Tolerance; Thiophenes; Thymidylate Synthase; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
Dimerization of mitochondrial Bax is associated with increased drug response in Bax-transfected A253 cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Carcinoma, Squamous Cell; Cytochrome c Group; Dimerization; Dose-Response Relationship, Drug; Enzyme Activation; Head and Neck Neoplasms; Humans; Mitochondria; Neoplasm Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Thiophenes; Thymidylate Synthase; Transfection; Tumor Cells, Cultured | 1999 |
Fas ligand is expressed on human squamous cell carcinomas of the head and neck, and it promotes apoptosis of T lymphocytes.
Topics: Apoptosis; Carcinoma, Squamous Cell; Fas Ligand Protein; fas Receptor; Head and Neck Neoplasms; Humans; Immunoblotting; Jurkat Cells; Lymphocytes, Tumor-Infiltrating; Membrane Glycoproteins; Phenylalanine; RNA, Messenger; Thiophenes; Tumor Cells, Cultured | 1999 |
Overexpression of Bax enhances antitumor activity of chemotherapeutic agents in human head and neck squamous cell carcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Camptothecin; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Enzyme Inhibitors; Female; Head and Neck Neoplasms; Humans; Irinotecan; Mice; Mice, Nude; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Thiophenes; Thymidylate Synthase; Topoisomerase I Inhibitors; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Expression of collagenase-3 (MMP-13) enhances invasion of human fibrosarcoma HT-1080 cells.
Topics: Adenoviridae; Basement Membrane; Carcinoma, Squamous Cell; Collagen; Collagen Type I; Collagenases; DNA, Complementary; Drug Combinations; Fibrosarcoma; Genetic Vectors; Humans; Laminin; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Genetic; Neoplasm Invasiveness; Neoplasm Metastasis; Phenylalanine; Proteoglycans; Thiophenes; Tissue Inhibitor of Metalloproteinase-3; Transfection; Tumor Cells, Cultured | 2002 |
Stromelysin-1 activation correlates with invasiveness in squamous cell carcinoma.
Topics: Biocompatible Materials; Carcinoma, Squamous Cell; Cell Movement; Collagen; Drug Combinations; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Keratinocytes; Laminin; Matrix Metalloproteinase 3; Neoplasm Invasiveness; Phenylalanine; Protease Inhibitors; Proteoglycans; Skin Neoplasms; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured | 2002 |
Comparative carcinogenicity of 5-nitrothiophenes and 5-nitrofurans in rats.
Topics: Adenocarcinoma; Adenofibroma; Animals; Carcinogens; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Female; Hemangioendothelioma; Intestinal Neoplasms; Leiomyosarcoma; Male; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Nitrofurans; Rats; Sarcoma, Experimental; Thiophenes | 1976 |
Evaluation of the carcinogenic potency of 4 environmental polycyclic aromatic compounds following intrapulmonary application in rats.
Topics: Animals; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Chrysenes; Dose-Response Relationship, Drug; Female; Injections; Lung Neoplasms; Phenanthrenes; Polycyclic Compounds; Rats; Thiophenes | 1990 |
17-(5-Substituted 2-thienyl) and 17-(5-substituted 2-thienylidene) derivatives of selected 17-keto steroids.
Topics: 17-Ketosteroids; Androstanes; Androsterone; Animals; Carcinoma, Squamous Cell; Cell Division; Culture Techniques; Dogs; Estrogens; Estrone; Female; Heart; Heart Atria; Humans; Ketones; Lithium; Magnetic Resonance Spectroscopy; Mice; Muscle Contraction; Rabbits; Stimulation, Chemical; Thiophenes; Uterus | 1969 |
Nitrogen mustard type derivatives of thiophene and benzo[b]thiophene.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Chemistry, Organic; Culture Techniques; Humans; Nasopharyngeal Neoplasms; Nitrogen Mustard Compounds; Organic Chemistry Phenomena; Rats; Thiophenes | 1966 |