Page last updated: 2024-08-18

thiophenes and Cancer of Stomach

thiophenes has been researched along with Cancer of Stomach in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's3 (13.04)18.2507
2000's9 (39.13)29.6817
2010's8 (34.78)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Chen, X; Dai, J; Hu, C; Lin, X; Yu, J1
Chen, X; Cheng, S; Dai, X; Ding, L; Guo, H; Guo, Q; Wang, J; Wang, T; Xu, X; Zhang, W1
Guo, F; Zhou, Y1
Chi, Y; Jiang, ZC1
Cao, H; Jiang, S; Liu, Y; Shao, C; Shao, S; Yuan, R; Zhang, W1
Chen, YX; Geng, HY; Qin, SK; Wang, L; Xu, HJ; Xue, S; Yang, AZ1
Ding, Z; Tang, L; Zhao, P; Zhou, X1
Ahn, SM; Chang, WJ; Cho, JH; Jung, KS; Kang, WK; Kim, HS; Kim, KM; Kim, ST; Kim, SY; Lee, I; Lee, J; Lee, JY; Lee, S; Lim, HY; Lim, SH; Park, JO; Park, SH; Park, YS; Song, HN; Yoo, KH1
Liu, Y; Shi, M; Wang, C; Wen, Z; Xie, J; Xue, Y; Zhang, S; Zhao, L; Zhao, Y1
Guan, W; Liu, B; Qian, X; Shen, J; Wang, H; Wei, J; Xie, L; Yu, L; Zou, Z1
Boige, V; Ducreux, M1
Depisch, D; Kornek, GV; Lang, F; Lenauer, A; Raderer, M; Scheithauer, W; Schmid, KE; Schüll, B1
Gao, H; Gu, B; Li, M; Lü, H; Wan, Y; Wu, D1
Bjarnason, GA; Charpentier, D; Dent, S; Douglas, L; Goel, R; Matthews, S; Seymour, L; Walsh, W; Winquist, E; Wong, R1
Amoroso, V; Ferrari, VD; Fusi, A; Mambrini, A; Marini, G; Marpicati, P; Montini, E; Rangoni, G; Simoncini, E; Valcamonico, F; Vasalli, L1
Douglass, HO; Kelsen, DP; Meropol, NJ; Pazdur, R; Vincent, M; Willson, JK1
Furukawa, F; Ikezaki, S; Kasahara, K; Lee, IS; Nishikawa, A; Takahashi, M; Tanakamura, Z1
Anthony, DA; Eatock, MM; El-Abassi, M; Evans, TR; Paul, J; Smith, M; Soukop, M; Wilson, P1
Gu, B; Li, M; Lü, H; Wu, D1
Dolan, PM; Itoh, K; Kensler, TW; Kwak, MK; Ramos-Gomez, M; Talalay, P; Yamamoto, M1
Evans, TR; Fullarton, GM; Garcia-Vargas, J; Harris, AL; Lofts, FJ; Mackay, HJ; McDonald, AC; McInnes, A; Paul, J; Raby, N; Soukop, M1
Lam, LK; Zheng, BL1
Bueding, E; Wattenberg, LW1

Trials

7 trial(s) available for thiophenes and Cancer of Stomach

ArticleYear
Preliminary investigation of intraperitoneal raltitrexed in patients with gastric cancer.
    World journal of surgical oncology, 2014, Dec-30, Volume: 12

    Topics: Adult; Antimetabolites, Antineoplastic; Double-Blind Method; Female; Humans; Injections, Intraperitoneal; Male; Middle Aged; Neoplasm Seeding; Prospective Studies; Quinazolines; Stomach Neoplasms; Thiophenes

2014
Second-line treatment of advanced gastric cancer with oxaliplatin plus raltitrexed.
    Onkologie, 2003, Volume: 26, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free Survival; Female; Humans; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Quinazolines; Retreatment; Salvage Therapy; Stomach Neoplasms; Survival Rate; Thiophenes

2003
Phase I study of Tomudex and Doxorubicin in patients with locally advanced, inoperable or metastatic cancer (IND.98).
    Investigational new drugs, 2005, Volume: 23, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Quinazolines; Salvage Therapy; Stomach Neoplasms; Thiophenes

2005
Epirubicin, cisplatin, and raltitrexed in patients with advanced gastric and hepatobiliary carcinoma: a phase II study.
    American journal of clinical oncology, 2004, Volume: 27, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Cisplatin; Epirubicin; Female; Humans; Liver Neoplasms; Male; Middle Aged; Quinazolines; Stomach Neoplasms; Survival Analysis; Thiophenes

2004
Phase II study of ZD1694 in patients with advanced gastric cancer.
    American journal of clinical oncology, 1996, Volume: 19, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Alanine Transaminase; Antimetabolites, Antineoplastic; Aspartate Aminotransferases; Asthenia; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Leukopenia; Male; Middle Aged; Mucous Membrane; Nausea; Neoplasm Staging; Quinazolines; Remission Induction; Stomach Neoplasms; Thiophenes; Thrombocytopenia; Thymidylate Synthase; Vomiting

1996
A dose-finding study of raltitrexed (tomudex) with cisplatin and epirubicin in advanced gastro-oesophageal adenocarcinoma.
    British journal of cancer, 2000, Volume: 82, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Epirubicin; Esophageal Neoplasms; Female; Humans; Male; Middle Aged; Quinazolines; Stomach Neoplasms; Thiophenes; Treatment Outcome

2000
A phase II study of epirubicin, cisplatin and raltitrexed combination chemotherapy (ECT) in patients with advanced oesophageal and gastric adenocarcinoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Progression; Drug Hypersensitivity; Enteritis; Epirubicin; Esophageal Neoplasms; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neutropenia; Pulmonary Embolism; Quinazolines; Sepsis; Stomach Neoplasms; Survival Analysis; Thiophenes; Treatment Outcome

2001

Other Studies

16 other study(ies) available for thiophenes and Cancer of Stomach

ArticleYear
Raltitrexed regulates proliferation and apoptosis of HGC-27 cells by upregulating RSK4.
    BMC pharmacology & toxicology, 2022, 08-28, Volume: 23, Issue:1

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Quinazolines; Stomach Neoplasms; Thiophenes

2022
Ceritinib increases sensitivity of AKT inhibitors to gastric cancer.
    European journal of pharmacology, 2021, Apr-05, Volume: 896

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Glycogen Synthase Kinase 3 beta; Humans; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Pyrroles; Signal Transduction; Stomach Neoplasms; Sulfones; Thiophenes; Tumor Burden; Xenograft Model Antitumor Assays

2021
A selective sphingosine-1-phosphate receptor 1 agonist SEW-2871 aggravates gastric cancer by recruiting myeloid-derived suppressor cells.
    Journal of biochemistry, 2018, Jan-01, Volume: 163, Issue:1

    Topics: Animals; Cell Movement; Cell Proliferation; Cytokines; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Myeloid Cells; Neoplasms, Experimental; Oxadiazoles; Receptors, Lysosphingolipid; Sphingosine-1-Phosphate Receptors; Stomach Neoplasms; T-Lymphocytes, Cytotoxic; Thiophenes; Tumor Cells, Cultured; Tumor Microenvironment

2018
[Data review and analysis of 22 cases of gastric cancer associated with pregnancy].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2018, Aug-23, Volume: 40, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Signet Ring Cell; Cesarean Section; China; Female; Fluorouracil; Gastrectomy; Humans; Irinotecan; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Pregnancy; Pregnancy Complications, Neoplastic; Prognosis; Quinazolines; Stomach Neoplasms; Survival Rate; Thiophenes

2018
Inhibition of IκB Kinase 2 Attenuated the Proliferation and Induced Apoptosis of Gastric Cancer.
    Digestive diseases and sciences, 2019, Volume: 64, Issue:5

    Topics: Aged; Animals; Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Female; Humans; I-kappa B Kinase; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Random Allocation; Stomach Neoplasms; Thiophenes

2019
Raltitrexed induces mitochondrial‑mediated apoptosis in SGC7901 human gastric cancer cells.
    Molecular medicine reports, 2014, Volume: 10, Issue:4

    Topics: Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cytochromes c; G1 Phase Cell Cycle Checkpoints; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oligopeptides; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Thiophenes; Thymidylate Synthase

2014
MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Female; Humans; Lactic Acid; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Monocarboxylic Acid Transporters; Muscle Proteins; Peritoneal Neoplasms; RNA Interference; RNA, Small Interfering; Stomach Neoplasms; Symporters; Thiophenes; Up-Regulation; Uracil; Xenograft Model Antitumor Assays

2016
MACC1 mediates chemotherapy sensitivity of 5-FU and cisplatin via regulating MCT1 expression in gastric cancer.
    Biochemical and biophysical research communications, 2017, 04-08, Volume: 485, Issue:3

    Topics: Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Survival; Cisplatin; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Monocarboxylic Acid Transporters; Multivariate Analysis; Prognosis; Pyrimidinones; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Stomach Neoplasms; Symporters; Thiophenes; Trans-Activators; Transcription Factors

2017
Thymidylate synthase mRNA levels in plasma and tumor as potential predictive biomarkers for raltitrexed sensitivity in gastric cancer.
    International journal of cancer, 2012, Sep-15, Volume: 131, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Female; Humans; Male; Middle Aged; Quinazolines; RNA, Messenger; Stomach Neoplasms; Thiophenes; Thymidylate Synthase

2012
Treatment of advanced gastric cancer: where we are in 2003.
    Onkologie, 2003, Volume: 26, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Disease Progression; Humans; Neoplasm Metastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Rate; Thiophenes; Treatment Outcome

2003
Potentiation of docetaxel antitumor activity by batimastat against mouse forestomach carcinoma.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2001, Volume: 16, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Synergism; Male; Mice; Neoplasm Transplantation; Phenylalanine; Stomach Neoplasms; Taxoids; Thiophenes; Tumor Cells, Cultured

2001
Chemopreventive activity of oltipraz against induction of glandular stomach carcinogenesis in rats by N-methyl-N'-nitro-N-nitrosoguanidine.
    Carcinogenesis, 1998, Volume: 19, Issue:2

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Hyperplasia; Male; Methylnitronitrosoguanidine; Pylorus; Pyrazines; Rats; Rats, Wistar; Stomach Neoplasms; Thiones; Thiophenes

1998
Potentiation of docetaxel antitumor activity by batimastat against mouse forestomach carcinoma.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2000, Volume: 19, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Dose-Response Relationship, Drug; Male; Mice; Paclitaxel; Phenylalanine; Stomach Neoplasms; Taxoids; Thiophenes

2000
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Mar-13, Volume: 98, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; Cell Nucleus; Disease Models, Animal; Disease Susceptibility; DNA-Binding Proteins; Epoxide Hydrolases; Female; FMN Reductase; Gene Expression; Genotype; Glucuronosyltransferase; Glutathione Transferase; Mice; Mice, Inbred ICR; Mice, Knockout; NADH, NADPH Oxidoreductases; NF-E2-Related Factor 2; Pyrazines; Stomach Neoplasms; Thiones; Thiophenes; Trans-Activators

2001
Inhibitory effects of 2-n-heptylfuran and 2-n-butylthiophene on benzo[a]pyrene-induced lung and forestomach tumorigenesis in A/J mice.
    Nutrition and cancer, 1992, Volume: 17, Issue:1

    Topics: Animals; Benzo(a)pyrene; Enzyme Induction; Female; Furans; Glutathione; Glutathione Transferase; Lung Neoplasms; Mice; Stomach Neoplasms; Thiophenes

1992
Inhibitory effects of 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (Oltipraz) on carcinogenesis induced by benzo[a]pyrene, diethylnitrosamine and uracil mustard.
    Carcinogenesis, 1986, Volume: 7, Issue:8

    Topics: Animals; Benzo(a)pyrene; Diethylnitrosamine; Female; Lung Neoplasms; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Pyrazines; Stomach Neoplasms; Thiones; Thiophenes; Uracil Mustard

1986