thiophenes has been researched along with Cancer of Head in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.23) | 18.7374 |
| 1990's | 6 (19.35) | 18.2507 |
| 2000's | 15 (48.39) | 29.6817 |
| 2010's | 8 (25.81) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Bauer, RJ; Ehrenschwender, M; Hammer, KP; Heimer, S; Jantsch, J; Knoll, G; Neubert, P; Wagner, S | 1 |
| Barbe, AG | 1 |
| Forbes, B; Garcia, CMA; Malallah, OS; Proctor, GB; Royall, PG | 1 |
| Boyers, A; Chadwick, A; Critchlow, SE; Mehibel, M; Mueller-Klieser, W; Ortiz-Martinez, F; Stratford, IJ; Telfer, BA; Voelxen, N; West, CM; Williams, KJ | 1 |
| Brands, RC; El-Mesery, M; Hartmann, S; Kübler, AC; Müller-Richter, UDA; Scheurer, MJJ; Seher, A | 1 |
| Alves, MV; Fitzgerald, AL; Frederick, MJ; Gadhikar, MA; Myers, JN; Neskey, DM; Osman, AA; Pickering, CR; Sciuto, MR; Zhao, M | 1 |
| Frederick, M; Johnson, FM; Kalu, NN; Li, L; Mazumdar, T; Myers, JN; Peng, S; Pickering, CR; Sambandam, V; Shen, L; Singh, R; Tong, P; Wang, J; Zhang, M | 1 |
| Chambers, MS; Stinnett, S; Witsell, DL | 1 |
| Baldi, A; Citro, G; Fanciulli, M; Spugnini, EP | 1 |
| Avallone, A; Caponigro, F; Comella, G; Comella, P; De Lucia, L; De Rosa, P; De Rosa, V; Rosati, G | 1 |
| Bruce, SD | 1 |
| Aframian, DJ; Nahlieli, O; Palmon, A | 1 |
| Bjarnason, GA; Charpentier, D; Dent, S; Douglas, L; Goel, R; Matthews, S; Seymour, L; Walsh, W; Winquist, E; Wong, R | 1 |
| de Jong, M; Jansen, P; Kerrebijn, J; Planting, A; Smith, M; Verweij, J | 1 |
| Johnstone, PA; Kahn, ST | 1 |
| Armstrong, I; Biel, MA; Chambers, MS; Hodge, KM; Jones, CU; Posner, M; Vitti, R; Weber, RS; Yen, C | 1 |
| Avallone, A; Bruzzese, F; Budillon, A; Caraglia, M; Comella, P; Delrio, P; Di Gennaro, E; Laus, G; Pepe, S | 1 |
| Armstrong, I; Biel, MA; Chambers, MS; Chen, Y; Garden, AS; Haddad, R; Hodge, KM; Holland, JM; Jones, CU; Ship, JA; Vitti, R; Weber, RS | 1 |
| Cheson, BD; Phillips, PH; Sorensen, JM | 1 |
| Ara, G; Chen, YN; Coleman, CN; Recht, A; Teicher, BA | 1 |
| Cao, S; McGuire, JJ; Rustum, YM | 1 |
| Azrak, RG; Cao, S; Guo, B; Rustum, YM; Tóth, K; Yin, MB | 1 |
| Atarshi, Y; Balkir, L; Gastman, BR; Rabinowich, H; Reichert, TE; Saito, T; Whiteside, TL | 1 |
| Avallone, A; Blackie, R; Budillon, A; Caponigro, F; Cartenì, G; Casaretti, R; Catalano, G; Comella, G; Comella, P; De Lucia, L; De Vita, F; Gravina, A; McLeod, H; Morsman, J | 1 |
| Azrak, RG; Cao, S; Guo, B; Rustum, YM; Tóth, K | 1 |
| Clarke, SJ; Dalley, D; Davidson, YE; Green, M; Mitchell, PL; Olver, I; Rischin, D; Zalcberg, J | 1 |
| Avallone, A; Budillon, A; Caponigro, F; Comella, G; Comella, P; De Rosa, V; Di Gennaro, E; Ionna, F; Manzione, L; Mozzillo, N; Rivellini, F | 1 |
| Avallone, A; Caponigro, F; Comella, G; Comella, P; De Rosa, V; Ionna, F; Rivellini, F | 1 |
| Baatenburg de Jong, RJ; Keizer, HJ; ten Bokkel Huinink, D; Tesselaar, ME; Verschuur, HP | 1 |
| Avallone, A; Budillon, A; Caponigro, F; Comella, G; Comella, P | 1 |
| Gastpar, H | 1 |
5 review(s) available for thiophenes and Cancer of Head
| Article | Year |
|---|---|
Buccal drug delivery technologies for patient-centred treatment of radiation-induced xerostomia (dry mouth).
Topics: Drug Delivery Systems; Head and Neck Neoplasms; Humans; Mouth Mucosa; Muscarinic Agonists; Pilocarpine; Quinuclidines; Radiation Injuries; Saliva; Thiophenes; Time Factors; Xerostomia | 2018 |
Preclinical models in electrochemotherapy: the role of veterinary patients.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Cat Diseases; Cats; Cisplatin; Dog Diseases; Dogs; Drug Evaluation, Preclinical; Electrochemotherapy; Epirubicin; Head and Neck Neoplasms; Melanoma; Mitoxantrone; Neoplasms; Quinazolines; Sarcoma; Thiophenes | 2012 |
Radiation-induced xerostomia: how dry is your patient?
Topics: Acupuncture Therapy; Head and Neck Neoplasms; Humans; Muscarinic Agonists; Nurse's Role; Nursing Assessment; Oncology Nursing; Oral Hygiene; Pilocarpine; Quality of Life; Quinuclidines; Radiotherapy; Radiotherapy Dosage; Salivation; Thiophenes; Xerostomia | 2004 |
Management of xerostomia related to radiotherapy for head and neck cancer.
Topics: Acupuncture Therapy; Amifostine; Clinical Trials as Topic; Head and Neck Neoplasms; Humans; Muscarinic Agonists; Palliative Care; Pilocarpine; Quinuclidines; Radiation-Protective Agents; Radiotherapy; Submandibular Gland; Thiophenes; Xerostomia | 2005 |
Raltitrexed/5-fluorouracil-based combination chemotherapy regimens in anticancer therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Neoplasm Metastasis; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Rectal Neoplasms; Thiophenes | 2001 |
10 trial(s) available for thiophenes and Cancer of Head
| Article | Year |
|---|---|
Effectiveness of cevimeline to improve oral health in patients with postradiation xerostomia.
Topics: Carcinoma, Squamous Cell; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Muscarinic Agonists; Oral Health; Quality of Life; Quinuclidines; Radiotherapy; Salivary Glands; Severity of Illness Index; Thiophenes; Xerostomia | 2012 |
Cisplatin, raltitrexed, levofolinic acid and 5-fluorouracil in locally advanced or metastatic squamous cell carcinoma of the head and neck: a phase II randomized study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Fluorouracil; Head and Neck Neoplasms; Hematologic Diseases; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Neutropenia; Quinazolines; Thiophenes; Treatment Outcome | 2002 |
Phase I study of Tomudex and Doxorubicin in patients with locally advanced, inoperable or metastatic cancer (IND.98).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Quinazolines; Salvage Therapy; Stomach Neoplasms; Thiophenes | 2005 |
Phase I study of concomitant chemoradiation with raltitrexed in locally advanced head and neck cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Quinazolines; Radiotherapy; Thiophenes | 2005 |
Cevimeline for the treatment of postirradiation xerostomia in patients with head and neck cancer.
Topics: Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Muscarinic Antagonists; Quinuclidines; Salivation; Thiophenes; Xerostomia | 2007 |
Phase I and pharmacokinetic study of tomudex combined with 5-fluorouracil plus levofolinic acid in advanced head and neck cancer and colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Middle Aged; Quinazolines; Thiophenes | 1999 |
Open label, multi-centre phase II study of raltitrexed ('Tomudex') in patients with inoperable squamous-cell carcinoma of head and neck.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Quinazolines; Survival Analysis; Thiophenes; Treatment Outcome | 2000 |
Cisplatin, raltitrexed, levofolinic acid and 5-fluorouracil in locally advanced or metastatic squamous cell carcinoma of the head and neck: a phase I-II trial of the Southern Italy Cooperative Oncology Group (SICOG).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Middle Aged; Neutropenia; Quinazolines; Thiophenes; Treatment Outcome | 2000 |
Phase I study of mitoxantrone, raltitrexed, levofolinic acid and 5-fluorouracil in advanced solid tumours.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Middle Aged; Mitoxantrone; Neoplasms; Quinazolines; Thiophenes | 2001 |
A phase I study of a fixed dose of cisplatin with increasing doses of raltitrexed (Tomudex) in the treatment of patients with locally advanced or metastatic squamous cell carcinoma of the head and neck.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Quinazolines; Thiophenes; Treatment Outcome | 2001 |
16 other study(ies) available for thiophenes and Cancer of Head
| Article | Year |
|---|---|
Hypertonicity counteracts MCL-1 and renders BCL-XL a synthetic lethal target in head and neck cancer.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Synergism; Head and Neck Neoplasms; Humans; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Osmotic Pressure; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; RNA Interference; Thiophenes; Tumor Microenvironment | 2021 |
Long-term Use of the Sialogogue Medications Pilocarpine and Cevimeline Can Reduce Xerostomia Symptoms and Increase Salivary Flow in Head and Neck Cancer Survivors After Radiotherapy.
Topics: Head and Neck Neoplasms; Humans; Pilocarpine; Quinuclidines; Survivors; Thiophenes; Xerostomia | 2017 |
Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters.
Topics: Animals; Biomarkers; Head and Neck Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactic Acid; Mice; Monocarboxylic Acid Transporters; Oxidative Phosphorylation; Precision Medicine; Prognosis; Pyrimidinones; Thiophenes | 2018 |
The Selection of NFκB Inhibitors to Block Inflammation and Induce Sensitisation to FasL-Induced Apoptosis in HNSCC Cell Lines Is Critical for Their Use as a Prospective Cancer Therapy.
Topics: Amides; Anti-Inflammatory Agents; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Fas Ligand Protein; Head and Neck Neoplasms; Humans; Hydrocortisone; Interleukin-8; NF-kappa B; Phenyl Ethers; Pyrimidines; Quinazolines; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Thiophenes; Tumor Necrosis Factor-alpha | 2019 |
Chk1/2 inhibition overcomes the cisplatin resistance of head and neck cancer cells secondary to the loss of functional p53.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Line, Tumor; Cellular Senescence; Checkpoint Kinase 1; Checkpoint Kinase 2; Cisplatin; DNA Damage; Drug Resistance, Neoplasm; Head and Neck Neoplasms; Humans; Mitosis; Molecular Targeted Therapy; Mutation; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Thiophenes; Tumor Suppressor Protein p53; Urea | 2013 |
Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Dose-Response Relationship, Drug; G2 Phase Cell Cycle Checkpoints; Genotype; Head and Neck Neoplasms; Humans; LIM Domain Proteins; Mice, Nude; Molecular Targeted Therapy; Mutation; Nuclear Proteins; Phenotype; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pteridines; Pyrazoles; Pyrimidines; Pyrimidinones; ras Proteins; RNA Interference; Signal Transduction; Smad4 Protein; Squamous Cell Carcinoma of Head and Neck; Thiophenes; Time Factors; Transfection; Tumor Burden; Urea; Xenograft Model Antitumor Assays | 2017 |
[Future therapy strategies for salivary gland impairment].
Topics: Amifostine; Cranial Irradiation; Head and Neck Neoplasms; Humans; Muscarinic Agonists; Pilocarpine; Quinuclidines; Radiation Injuries; Radiation-Protective Agents; Regeneration; Saliva; Salivary Glands; Thiophenes | 2004 |
Synergistic antitumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Leucovorin; Quinazolines; Thiophenes | 2007 |
Open-label, long-term safety study of cevimeline in the treatment of postirradiation xerostomia.
Topics: Adult; Aged; Aged, 80 and over; Diarrhea; Dyspepsia; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Muscarinic Agonists; Nausea; Quinuclidines; Radiotherapy Dosage; Sweat; Thiophenes; Xerostomia | 2007 |
Clinical trials referral resource. Clinical trials with tomudex.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Colorectal Neoplasms; Enzyme Inhibitors; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leukemia; Male; Prostatic Neoplasms; Quinazolines; Thiophenes; Thymidylate Synthase | 1996 |
Interaction of tomudex with radiation in vitro and in vivo.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Lewis Lung; Carcinoma, Squamous Cell; Cell Survival; Combined Modality Therapy; Drug Interactions; Enzyme Inhibitors; Fluorouracil; Head and Neck Neoplasms; HT29 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms; Quinazolines; Radiation Tolerance; Thiophenes; Thymidylate Synthase; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
Antitumor activity of ZD1694 (tomudex) against human head and neck cancer in nude mouse models: role of dosing schedule and plasma thymidine.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Quinazolines; Thiophenes; Thymidine; Transplantation, Heterologous; Tumor Cells, Cultured | 1999 |
Dimerization of mitochondrial Bax is associated with increased drug response in Bax-transfected A253 cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Carcinoma, Squamous Cell; Cytochrome c Group; Dimerization; Dose-Response Relationship, Drug; Enzyme Activation; Head and Neck Neoplasms; Humans; Mitochondria; Neoplasm Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Thiophenes; Thymidylate Synthase; Transfection; Tumor Cells, Cultured | 1999 |
Fas ligand is expressed on human squamous cell carcinomas of the head and neck, and it promotes apoptosis of T lymphocytes.
Topics: Apoptosis; Carcinoma, Squamous Cell; Fas Ligand Protein; fas Receptor; Head and Neck Neoplasms; Humans; Immunoblotting; Jurkat Cells; Lymphocytes, Tumor-Infiltrating; Membrane Glycoproteins; Phenylalanine; RNA, Messenger; Thiophenes; Tumor Cells, Cultured | 1999 |
Overexpression of Bax enhances antitumor activity of chemotherapeutic agents in human head and neck squamous cell carcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Camptothecin; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Enzyme Inhibitors; Female; Head and Neck Neoplasms; Humans; Irinotecan; Mice; Mice, Nude; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Thiophenes; Thymidylate Synthase; Topoisomerase I Inhibitors; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Inhibition of cancer cell stickiness by the blocking of platelet aggregation.
Topics: Adhesiveness; Animals; Antineoplastic Agents; Blood Cell Count; Blood Platelets; Capillaries; Carcinoma 256, Walker; Dipyridamole; Embolism; Endothelium; Head; Head and Neck Neoplasms; Humans; Lung Neoplasms; Morpholines; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Cells, Circulating; Piperidines; Platelet Adhesiveness; Pulmonary Embolism; Pyrimidines; Rats; Sarcoma; Thiophenes; Transplantation, Homologous; Vasodilator Agents | 1974 |