Compounds > thiophenes
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thiophenes and Bone Neoplasms

thiophenes has been researched along with Bone Neoplasms in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (38.89)29.6817
2010's7 (38.89)24.3611
2020's4 (22.22)2.80

Authors

AuthorsStudies
Duvall, CL; Guelcher, SA; Gupta, MK; Johnson, RW; Kwakwa, KA; Merkel, AR; Rhoades, JA; Vanderburgh, JP; Werfel, TA1
Bedingfield, SK; d'Arcy, R; Duvall, CL; Guelcher, SA; Gupta, MK; Hill, JL; Kwakwa, KA; Merkel, AR; Moyer, K; Rhoades, JA; Vanderburgh, J; Wang, SK1
Bedoya, CAF; Buzbee, M; Harden, A; Marmonti, E; Morrell, MG; Savage, H; Schadler, K; Zhang, A1
Dean, DC; Duan, Z; Hornicek, FJ; Nelson, SD; Thanindratarn, P1
Dadwal, UC; Kessler, M; Kwakwa, KA; Merkel, AR; Page, JM; Rhoades, JA1
Cui, JH; Ju, J; Yoon, MH1
Bogado, RF; Brassesco, MS; de Oliveira, HF; Pezuk, JA; Tone, LG1
Baranski, Z; Booij, TH; Bovée, JV; Cleton-Jansen, AM; Danen, EH; Hogendoorn, PC; Price, LS; van de Water, B1
Chirgwin, JM; Suvannasankha, A1
Akram, MM; Bisht, K; Brogi, E; Camphausen, K; Degenhardt, YY; Edelman, DC; Hua, E; Killian, JK; Lampkin, TA; Laquerre, S; Liewehr, DJ; Meltzer, PS; Palmieri, D; Pineda, M; Qian, Y; Scurci, S; Skordos, KW; Steeg, PS; Steinberg, SM; Woditschka, S1
Guo, W; Tang, BQ; Tang, S; Tang, XD; Yan, TQ; Yang, RL1
Bjarnason, GA; Charpentier, D; Dent, S; Douglas, L; Goel, R; Matthews, S; Seymour, L; Walsh, W; Winquist, E; Wong, R1
Cooper, RD; Daniel-Issakani, S; Goff, D; Goldstein, E; Gururaja, TL; Hitoshi, Y; Huang, J; Kinoshita, T; McLaughlin, J; Pali, E; Payan, DG; Singh, R; Yung, S1
Cremers, S; Garnero, P1
Bone, E; Lee, J; Mejia, S; Orr, W; Watson, P; Weber, M1
Anderson, RL; Bissell, MJ; Le Beyec, J1
Bhagat, S; Che, M; Cher, ML; Fridman, R; Herzog, M; Mullins, C; Nemeth, JA; Shekarriz, B; Upadhyay, J; Yousif, R1
Andersen, TL; Brünner, N; Delaissé, JM; Foged, NT; Heegaard, AM; Holst-Hansen, C; Høegh-Andersen, P; Misander, H; NicAmhlaoibh, R; Winding, B1

Reviews

2 review(s) available for thiophenes and Bone Neoplasms

ArticleYear
Role of bone-anabolic agents in the treatment of breast cancer bone metastases.
    Breast cancer research : BCR, 2014, Volume: 16, Issue:6

    Topics: Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Boronic Acids; Bortezomib; Breast Neoplasms; Everolimus; Female; Humans; Oligopeptides; Osteoblasts; Parathyroid Hormone; Proteasome Inhibitors; Pyrazines; Recombinant Fusion Proteins; Sirolimus; Thiophenes; Transforming Growth Factor beta

2014
Biochemical markers of bone turnover in the clinical development of drugs for osteoporosis and metastatic bone disease: potential uses and pitfalls.
    Drugs, 2006, Volume: 66, Issue:16

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biomarkers; Bone Density; Bone Diseases, Metabolic; Bone Neoplasms; Bone Remodeling; Bone Resorption; Calcitonin; Cathepsin K; Cathepsins; Collagen Type I; Denosumab; Diphosphonates; Drug Administration Schedule; Drug Design; Female; Humans; Organometallic Compounds; Osteitis Deformans; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Parathyroid Hormone; Raloxifene Hydrochloride; RANK Ligand; Thiophenes

2006

Trials

2 trial(s) available for thiophenes and Bone Neoplasms

ArticleYear
[Evaluation of efficacy and safety of rivaroxaban in the prevention of postoperative venous thromboembolism in adult patients with primary bone tumor undergoing knee operation].
    Zhonghua yi xue za zhi, 2012, Oct-23, Volume: 92, Issue:39

    Topics: Adult; Anticoagulants; Bone Neoplasms; Female; Humans; Knee; Male; Middle Aged; Morpholines; Postoperative Complications; Prospective Studies; Rivaroxaban; Thiophenes; Treatment Outcome; Venous Thromboembolism; Young Adult

2012
Phase I study of Tomudex and Doxorubicin in patients with locally advanced, inoperable or metastatic cancer (IND.98).
    Investigational new drugs, 2005, Volume: 23, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Quinazolines; Salvage Therapy; Stomach Neoplasms; Thiophenes

2005

Other Studies

14 other study(ies) available for thiophenes and Bone Neoplasms

ArticleYear
Systemic delivery of a Gli inhibitor via polymeric nanocarriers inhibits tumor-induced bone disease.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, Volume: 311-312

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Drug Liberation; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Animal; Mesenchymal Stem Cells; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Nanoparticles; Osteogenesis; Polymers; Pyridines; Thiophenes; Zinc Finger Protein Gli2

2019
Tuning Ligand Density To Optimize Pharmacokinetics of Targeted Nanoparticles for Dual Protection against Tumor-Induced Bone Destruction.
    ACS nano, 2020, 01-28, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Humans; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; Nanoparticles; Optical Imaging; Particle Size; Polymers; Pyridines; Surface Properties; Thiophenes; X-Ray Microtomography

2020
Modulating sphingosine-1-phosphate receptors to improve chemotherapy efficacy against Ewing sarcoma.
    International journal of cancer, 2020, 08-15, Volume: 147, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Bone Neoplasms; Capillary Permeability; Cell Line, Tumor; Doxorubicin; Endothelial Cells; Humans; Mice, Nude; Oxadiazoles; Pyrazoles; Pyridines; Sarcoma, Ewing; Sphingosine 1 Phosphate Receptor Modulators; Sphingosine-1-Phosphate Receptors; Thiophenes; Treatment Outcome; Xenograft Model Antitumor Assays

2020
T-LAK cell-originated protein kinase (TOPK) is a Novel Prognostic and Therapeutic Target in Chordoma.
    Cell proliferation, 2020, Volume: 53, Issue:10

    Topics: Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Chordoma; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Neoplasm Metastasis; Prognosis; Protein Kinase Inhibitors; Quinolones; RNA Interference; RNA, Small Interfering; Thiophenes

2020
3D Bone Morphology Alters Gene Expression, Motility, and Drug Responses in Bone Metastatic Tumor Cells.
    International journal of molecular sciences, 2020, Sep-21, Volume: 21, Issue:18

    Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Models, Biological; Neoplasm Metastasis; Neoplasm Proteins; Pyridines; Thiophenes; Tissue Scaffolds

2020
Pharmacology of cannabinoid receptor agonists and a cyclooxygenase-2 inhibitor in rat bone tumor pain.
    Pharmacology, 2013, Volume: 92, Issue:3-4

    Topics: Animals; Arachidonic Acids; Bone Neoplasms; Cannabinoid Receptor Agonists; Cannabinoids; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Hyperalgesia; Pain; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Messenger; Spinal Cord; Thiophenes; Tibia

2013
BI 6727 and GSK461364 suppress growth and radiosensitize osteosarcoma cells, but show limited cytotoxic effects when combined with conventional treatments.
    Anti-cancer drugs, 2015, Volume: 26, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Bone Neoplasms; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Osteosarcoma; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Radiation Tolerance; Radiation-Sensitizing Agents; Thiophenes

2015
Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.
    The Journal of pathology, 2015, Volume: 236, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Antibiotics, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Ataxia Telangiectasia Mutated Proteins; Bone Neoplasms; Cell Line, Tumor; Checkpoint Kinase 1; DNA Damage; Doxorubicin; G2 Phase Cell Cycle Checkpoints; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Oligonucleotide Array Sequence Analysis; Osteosarcoma; Phosphorylation; Protein Kinases; RNA Interference; Signal Transduction; Thiophenes; Urea

2015
Inhibition of Polo-like kinase 1 prevents the growth of metastatic breast cancer cells in the brain.
    Clinical & experimental metastasis, 2011, Volume: 28, Issue:8

    Topics: Animals; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cell Cycle Proteins; Cell Proliferation; Female; Humans; Immunoenzyme Techniques; Lung Neoplasms; Mice; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Radiation, Ionizing; Survival Rate; Thiophenes; Tissue Array Analysis; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2011
R-253 disrupts microtubule networks in multiple tumor cell lines.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jun-15, Volume: 12, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Flow Cytometry; HeLa Cells; Humans; Lung Neoplasms; Microtubules; Molecular Weight; Osteosarcoma; Pyrimidines; Thiophenes; Thiourea

2006
A matrix metalloproteinase inhibitor, batimastat, retards the development of osteolytic bone metastases by MDA-MB-231 human breast cancer cells in Balb C nu/nu mice.
    European journal of cancer (Oxford, England : 1990), 2001, Volume: 37, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Humans; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Phenylalanine; Thiophenes; Tumor Cells, Cultured

2001
Prostate cancer in bone: importance of context for inhibition of matrix metalloproteinases.
    Journal of the National Cancer Institute, 2002, Jan-02, Volume: 94, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Disease Models, Animal; Humans; Male; Matrix Metalloproteinase Inhibitors; Neoplasm Metastasis; Phenylalanine; Prostatic Neoplasms; Thiophenes

2002
Matrix metalloproteinase activity, bone matrix turnover, and tumor cell proliferation in prostate cancer bone metastasis.
    Journal of the National Cancer Institute, 2002, Jan-02, Volume: 94, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Bone Remodeling; Bone Transplantation; Calcium; Disease Models, Animal; Fetal Tissue Transplantation; Humans; Immunohistochemistry; In Situ Hybridization; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, SCID; Neoplasm Metastasis; Oligonucleotide Probes; Osteoclasts; Phenylalanine; Prostatic Neoplasms; RNA, Messenger; Thiophenes; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2002
Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cell Survival; Dipeptides; Female; Genetic Therapy; Humans; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Osteolysis; Phenylalanine; Protease Inhibitors; Thiophenes; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured

2002