thiophenes has been researched along with Anxiety in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (13.64) | 18.7374 |
| 1990's | 5 (11.36) | 18.2507 |
| 2000's | 9 (20.45) | 29.6817 |
| 2010's | 22 (50.00) | 24.3611 |
| 2020's | 2 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Cannavò, D; Caraci, F; Caruso, G; Drago, F; Leggio, GM; Salomone, S; Santagati, M | 1 |
| Ahn, KJ; Eisch, AJ; Spears, SL; Tran, FH; Yun, S | 1 |
| Geng, F; Lu, GF; Luo, Y; Peng, C; Tian, J; Wu, JL; Zou, WJ | 1 |
| Augustine, C; Brewer, C; Hefting, N; Hobart, M; McQuade, RD; Sanchez, R; Skuban, A; Zhang, P | 1 |
| Assié, MB; Auclair, AL; Bardin, L; Cussac, D; Depoortère, R; Heusler, P; Marien, M; Martel, JC; Newman-Tancredi, A; O'Connor, JA | 1 |
| Cohen, LS; Connors, S; Freeman, MP; Hirschberg, AM; Joffe, H; Petrillo, LF; Regan, S; Wang, B | 1 |
| Alain, B; Beatrix, R; Erich, S; Heinz, B; Holger, H; Lorenzo, P; Markus, R | 1 |
| DU, XN; Huang, F; Huang, ZF; Li, Y; Zhang, SL; Zhu, J | 1 |
| Assogna, F; Caltagirone, C; Fanciulli, A; Pontieri, FE; Spalletta, G | 1 |
| Alam, MY; Chen, Y; Jacobsen, PL; Mahableshwarkar, AR; Serenko, M | 1 |
| Berggren, L; Gilaberte, I; Lenox-Smith, A; Pérez, V; Quail, D; Romera, I | 1 |
| Skelly, MJ; Weiner, JL | 1 |
| Amador, A; Banerjee, S; Burris, TP; El-Gendy, BM; Griffett, K; Huitron-Resendiz, S; Kamenecka, TM; Kazantzis, M; Roberts, AJ; Shin, Y; Solt, LA; Wang, Y | 1 |
| Kingwell, K | 1 |
| Arulpragasam, AR; Chou, T; Corse, AK; Deckersbach, T; Dougherty, DD; Duffy, A; Jenike, MA; Keuthen, NJ | 1 |
| Hashimoto, S; Hattori, T; Kasahara, K; Kawakubo, H; Kawasaki, K; Nagatani, T; Nakazono, O; Takao, K; Tsujita, R | 1 |
| Baker, RA; Davis, LL; Ota, A; Perry, P; Tsuneyoshi, K; Weiller, E | 1 |
| Begley, A; Dew, MA; Karp, JF; Miller, MD; Reynolds, CF; Weiner, DK | 1 |
| Aung, GL; Kawamoto, LS; O'Brien, JG; Tien, PG | 1 |
| Chiesa, A; De Ronchi, D; Mencacci, C; Nasso, ED; Serretti, A | 1 |
| Kozumplik, O; Uzun, S | 1 |
| Ahl, J; Arnold, LM; Gaynor, PJ; Wang, F; Wohlreich, MM | 1 |
| Calabrese, F; Guidotti, G; Mancini, M; Molteni, R; Racagni, G; Riva, MA | 1 |
| Karaiskos, D; Paparrigopoulos, T; Spengos, K; Tzavellas, E; Vassilopoulou, S | 1 |
| Bourin, M; Hascoët, M; Nic Dhonnchadha, BA | 1 |
| Detke, MJ; Dunner, DL; Goldstein, DJ; Lu, Y; Mallinckrodt, C | 1 |
| Brocco, M; Dekeyne, A; Gobert, A; Millan, MJ | 1 |
| Bertaina-Anglade, V; La Rochelle, CD; Scheller, DK | 1 |
| Bourin, M; Hascoët, M; Massé, F; Nic Dhonnchadha, BA | 1 |
| Cohen, LS; Joffe, H; Koch, JK; Petrillo, LF; Soares, CN; Somley, BL; Viguera, AC | 1 |
| Bria, P; Catalano, V; Harnic, D; Janiri, L; Mazza, M | 1 |
| Möller, HJ; Müller, N; Riedel, M; Schennach, R | 1 |
| Bánki, CM; Vigváry, L | 1 |
| Andrews, N; File, SE; Gonzalez, LE; Hogg, S | 1 |
| File, SE; Gonzalez, LE | 1 |
| Baxter, GS; Blackburn, TP; Bright, F; Kennett, GA; Trail, B | 1 |
| Andrews, N; File, SE; Gonzalez, LE | 1 |
| Delagrange, P; Kopp, C; Lesieur, D; Misslin, R; Renard, P; Rettori, MC; Vogel, E | 1 |
| Klicpera, C; Strian, F | 1 |
| Banki, CM | 1 |
| Carroll, JD; Maclay, WP | 1 |
| Hussar, DA | 1 |
| Kasich, AM | 1 |
3 review(s) available for thiophenes and Anxiety
| Article | Year |
|---|---|
New antipsychotic drugs for the treatment of agitation and psychosis in Alzheimer's disease: focus on brexpiprazole and pimavanserin.
Topics: Alzheimer Disease; Antipsychotic Agents; Anxiety; Humans; Piperidines; Psychotic Disorders; Quinolones; Thiophenes; Urea | 2020 |
Duloxetine in the treatment of major psychiatric and neuropathic disorders.
Topics: Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Peripheral Nervous System Diseases; Practice Patterns, Physicians'; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2008 |
New drugs of 1972.
Topics: Acetals; Administration, Topical; Anthelmintics; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Anxiety; Benzazepines; Carboxylic Acids; Clindamycin; Drug Therapy; Flucytosine; Fluorometholone; Fluphenazine; Humans; Hypnotics and Sedatives; Ketosteroids; Megestrol; Pancuronium; Phenyl Ethers; Phosphoric Acids; Prednisolone; Pyrimidines; Thiophenes; Tranquilizing Agents; Vinyl Compounds | 1973 |
16 trial(s) available for thiophenes and Anxiety
| Article | Year |
|---|---|
A Randomized, Placebo-Controlled Study of the Efficacy and Safety of Fixed-Dose Brexpiprazole 2 mg/d as Adjunctive Treatment of Adults With Major Depressive Disorder.
Topics: Adult; Antidepressive Agents; Anxiety; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Psychiatric Status Rating Scales; Quinolones; Thiophenes; Treatment Outcome; Young Adult | 2018 |
Duloxetine for major depressive disorder and daytime and nighttime hot flashes associated with the menopausal transition.
Topics: Antidepressive Agents; Anxiety; Anxiety Disorders; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hot Flashes; Humans; Menopause; Middle Aged; Patient Selection; Severity of Illness Index; Thiophenes | 2013 |
[Impact of duloxetine on depression and anxiety in patients with ankylosing spondylitis: a case-control study].
Topics: Adult; Analgesics; Antidepressive Agents; Anxiety; Depression; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Spondylitis, Ankylosing; Thiophenes; Young Adult | 2013 |
Safety, tolerability, and efficacy of vortioxetine (Lu AA21004) in major depressive disorder: results of an open-label, flexible-dose, 52-week extension study.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety; Depression; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Sexual Dysfunction, Physiological; Suicidal Ideation; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine; Weight Gain; Young Adult | 2014 |
Open-label study of duloxetine for the treatment of obsessive-compulsive disorder.
Topics: Adolescent; Adult; Anxiety; Depression; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Psychotropic Drugs; Quality of Life; Thiophenes; Treatment Outcome; Young Adult | 2015 |
Adjunctive brexpiprazole in patients with major depressive disorder and anxiety symptoms: an exploratory study.
Topics: Anxiety; Depressive Disorder, Major; Dopamine Agonists; Drug Therapy, Combination; Female; Humans; Least-Squares Analysis; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotropic Drugs; Quinolones; Serotonin Agents; Thiophenes; Treatment Outcome | 2016 |
Clinical and demographic predictors of improvement during duloxetine treatment in patients with major depression: an open-label study.
Topics: Adult; Antidepressive Agents; Anxiety; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Treatment Outcome | 2011 |
Improvement in multiple dimensions of fatigue in patients with fibromyalgia treated with duloxetine: secondary analysis of a randomized, placebo-controlled trial.
Topics: Adult; Antidepressive Agents; Anxiety; Depression; Duloxetine Hydrochloride; Fatigue; Female; Fibromyalgia; Humans; Male; Middle Aged; Motor Activity; Musculoskeletal Pain; Pain Threshold; Patient Satisfaction; Placebos; Sleep Wake Disorders; Thiophenes; Treatment Outcome | 2011 |
Duloxetine versus citalopram and sertraline in the treatment of poststroke depression, anxiety, and fatigue.
Topics: Activities of Daily Living; Adult; Aged; Antidepressive Agents; Anxiety; Citalopram; Depression; Duloxetine Hydrochloride; Fatigue; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Sertraline; Stroke; Thiophenes; Time Factors; Treatment Outcome; Young Adult | 2012 |
Duloxetine in treatment of anxiety symptoms associated with depression.
Topics: Adult; Antidepressive Agents; Anxiety; Depression; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Severity of Illness Index; Surveys and Questionnaires; Thiophenes | 2003 |
Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine.
Topics: Adult; Anxiety; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hot Flashes; Humans; Middle Aged; Pain; Postmenopause; Selective Serotonin Reuptake Inhibitors; Single-Blind Method; Sleep Wake Disorders; Thiophenes; Treatment Outcome | 2007 |
Duloxetine for premenstrual dysphoric disorder: a pilot study.
Topics: Adrenergic Uptake Inhibitors; Adult; Affect; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Depression; Duloxetine Hydrochloride; Female; Humans; Pilot Projects; Premenstrual Syndrome; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Time Factors; Treatment Outcome | 2008 |
Anxiety, arousal, and autonomic habituation.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Arousal; Autonomic Nervous System; Azepines; Clinical Trials as Topic; Collateral Circulation; Double-Blind Method; Galvanic Skin Response; Habituation, Psychophysiologic; Heart Rate; Humans; Male; Respiration; Skin; Thiophenes | 1977 |
Clinical observations with pizotifene (Sandomigran) in the treatment of nonmigrainous depressed women.
Topics: Adult; Affective Disorders, Psychotic; Anxiety; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Humans; Middle Aged; Paranoid Disorders; Pizotyline; Thiophenes | 1978 |
Pizotifen (BC 105) in migraine prophylaxis.
Topics: Anxiety; Body Weight; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Depression; Hemiplegia; Humans; Migraine Disorders; Pizotyline; Thiophenes | 1975 |
A double-blind study of heteronium bromide and amobarbital in the management of gastrointestinal conditions associated with anxiety.
Topics: Adult; Aged; Amobarbital; Anxiety; Clinical Trials as Topic; Colonic Diseases, Functional; Duodenal Ulcer; Female; Gastrointestinal Motility; Humans; Male; Middle Aged; Peptic Ulcer; Phenobarbital; Placebos; Propantheline; Psychophysiologic Disorders; Pyrrolidines; Thiophenes | 1968 |
25 other study(ies) available for thiophenes and Anxiety
| Article | Year |
|---|---|
Does chronic systemic injection of the DREADD agonists clozapine-N-oxide or Compound 21 change behavior relevant to locomotion, exploration, anxiety, and depression in male non-DREADD-expressing mice?
Topics: Animals; Anxiety; Behavior, Animal; Clozapine; Depression; Designer Drugs; Exploratory Behavior; Imidazoles; Locomotion; Male; Mice, Inbred C57BL; Mice, Transgenic; Sulfonamides; Thiophenes | 2020 |
Dorsomedial prefrontal cortex 5-HT6 receptors regulate anxiety-like behavior.
Topics: Animals; Anxiety; Behavior; Indoles; Male; Mice, Inbred C57BL; Prefrontal Cortex; Pyridines; Receptors, Serotonin; Sulfonamides; Synaptic Transmission; Thiophenes | 2018 |
Levomilnacipran (F2695), a norepinephrine-preferring SNRI: profile in vitro and in models of depression and anxiety.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Cerebral Cortex; Cyclohexanols; Cyclopropanes; Depression; Dopamine; Duloxetine Hydrochloride; Humans; Male; Mice; Milnacipran; Motor Activity; Neurotransmitter Transport Proteins; Norepinephrine; Rats; Serotonin; Synaptosomes; Thiophenes; Venlafaxine Hydrochloride | 2013 |
Postictal ventricular tachycardia after electroconvulsive therapy treatment associated with a lithium-duloxetine combination.
Topics: Androstanols; Anesthesia; Antidepressive Agents; Antimanic Agents; Anxiety; Bipolar Disorder; Duloxetine Hydrochloride; Electrocardiography; Electroconvulsive Therapy; Female; Humans; Lithium Carbonate; Middle Aged; Neuromuscular Depolarizing Agents; Neuromuscular Nondepolarizing Agents; Psychomotor Agitation; Recurrence; Rocuronium; Succinylcholine; Tachycardia, Ventricular; Thiophenes | 2013 |
Rotigotine for anxiety during wearing-off in Parkinson's disease with dementia.
Topics: Aged; Anxiety; Dementia; Dopamine Agonists; Female; Humans; Parkinson Disease; Tetrahydronaphthalenes; Thiophenes | 2013 |
Individual residual symptoms and functional impairment in patients with depression.
Topics: Adult; Antidepressive Agents; Anxiety; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Sleep Wake Disorders; Thiophenes | 2014 |
Chronic treatment with prazosin or duloxetine lessens concurrent anxiety-like behavior and alcohol intake: evidence of disrupted noradrenergic signaling in anxiety-related alcohol use.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic Uptake Inhibitors; Alcohol Drinking; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Duloxetine Hydrochloride; Ethanol; Male; Prazosin; Rats; Rats, Long-Evans; Self Administration; Thiophenes | 2014 |
Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour.
Topics: Animals; Anxiety; ARNTL Transcription Factors; Behavior, Animal; Circadian Clocks; Circadian Rhythm; CLOCK Proteins; Cryptochromes; Feedback, Physiological; Gene Expression Regulation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nuclear Receptor Subfamily 1, Group D, Member 1; Period Circadian Proteins; Pyrrolidines; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Reward; Signal Transduction; Sleep, REM; Thiophenes | 2014 |
Sleep-related disorders: Expanding the applications of clock-gene modulation.
Topics: Animals; Anxiety; Behavior, Animal; Circadian Clocks; Male; Pyrrolidines; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Sleep, REM; Thiophenes | 2015 |
The effects of AP521, a novel anxiolytic drug, in three anxiety models and on serotonergic neural transmission in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Cells, Cultured; Citalopram; Diazepam; Disease Models, Animal; Drug Synergism; Humans; Isoindoles; Male; Piperazines; Prefrontal Cortex; Pyridines; Pyrimidines; Rats; Receptors, Serotonin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Synaptic Transmission; Thiophenes | 2015 |
Duloxetine: new indication. In generalised anxiety too? No thanks! No tangible efficacy but numerous and sometimes severe adverse effects.
Topics: Anxiety; Drug Approval; Europe; Humans; Randomized Controlled Trials as Topic; Thiophenes | 2009 |
Duloxetine and care management treatment of older adults with comorbid major depressive disorder and chronic low back pain: results of an open-label pilot study.
Topics: Aged; Anxiety; Chronic Disease; Comorbidity; Depressive Disorder, Major; Disability Evaluation; Disease Management; Duloxetine Hydrochloride; Female; Health Status; Humans; Low Back Pain; Male; Pain Measurement; Pilot Projects; Psychiatric Status Rating Scales; Quality of Life; Selective Serotonin Reuptake Inhibitors; Self Efficacy; Sleep; Surveys and Questionnaires; Thiophenes | 2010 |
Increased aripiprazole concentrations in an HIV-positive male concurrently taking duloxetine, darunavir, and ritonavir.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Anxiety; Aripiprazole; Cytochrome P-450 Enzyme Inhibitors; Darunavir; Depression; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; HIV Infections; HIV Protease Inhibitors; Humans; Male; Piperazines; Quinolones; Ritonavir; Sulfonamides; Thiophenes | 2010 |
Reinforcement of irritability during therapy with benzodiazepines.
Topics: Adult; Antidepressive Agents; Anxiety; Benzodiazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Duloxetine Hydrochloride; Humans; Hypnotics and Sedatives; Irritable Mood; Life Change Events; Male; Oxazepam; Pyridines; Self Medication; Thiophenes; Zolpidem | 2011 |
Stress-induced changes of hippocampal NMDA receptors: modulation by duloxetine treatment.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Duloxetine Hydrochloride; Gene Expression Regulation; Hippocampus; Male; Memory; Phosphorylation; Prefrontal Cortex; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spatial Behavior; Stress, Psychological; Thiophenes | 2012 |
Anxiolytic-like effects of 5-HT2 ligands on three mouse models of anxiety.
Topics: Amphetamines; Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylamines; Indoles; Ketanserin; Male; Maze Learning; Mice; Motor Activity; Naphthyridines; Piperazine; Piperazines; Psychomotor Performance; Pyridines; Reaction Time; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Thiophenes | 2003 |
Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade.
Topics: Acetamides; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain Chemistry; Clorazepate Dipotassium; Conflict, Psychological; Dose-Response Relationship, Drug; Hippocampus; Indoles; Interpersonal Relations; Male; Melatonin; Mice; Microdialysis; Motor Activity; Norepinephrine; Pyridines; Rats; Receptor, Serotonin, 5-HT2C; Receptors, GABA-A; Serotonin; Serotonin Antagonists; Synaptic Transmission; Thiophenes; Vocalization, Animal | 2005 |
Antidepressant properties of rotigotine in experimental models of depression.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Disease Models, Animal; Dopamine Agonists; Helplessness, Learned; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thiophenes | 2006 |
Anxiolytic-like effect of 5-HT(2) ligands and benzodiazepines co-administration: comparison of two animal models of anxiety (the four-plate test and the elevated plus maze).
Topics: Amphetamines; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Benzodiazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Indoles; Male; Maze Learning; Mice; Serotonin Receptor Agonists; Thiophenes | 2007 |
Sandomigran in the treatment of migrainous patients.
Topics: Anxiety; Body Weight; Female; Humans; Migraine Disorders; Pizotyline; Thiophenes | 1981 |
5-HT1A receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours respectively.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Anxiety; Autoreceptors; Dendrites; Grooming; Hippocampus; Male; Motor Activity; Propanolamines; Raphe Nuclei; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Social Behavior; Thiophenes | 1994 |
Anxiolytic effects in the plus-maze of 5-HT1A-receptor ligands in dorsal raphé and ventral hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anxiety; Hippocampus; Ligands; Male; Propanolamines; Raphe Nuclei; Rats; Receptors, Serotonin; Serotonin Receptor Agonists; Stereotaxic Techniques; Thiophenes | 1996 |
Effects of the 5-HT2B receptor agonist, BW 723C86, on three rat models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Chlordiazepoxide; Disease Models, Animal; Indoles; Male; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Thiophenes; Urea | 1996 |
5-HT1A and benzodiazepine receptors in the basolateral amygdala modulate anxiety in the social interaction test, but not in the elevated plus-maze.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholinesterase; Adrenergic beta-Antagonists; Amygdala; Analysis of Variance; Animals; Anxiety; GABA Modulators; Infusions, Parenteral; Male; Maze Learning; Midazolam; Motor Activity; Neurons; Propanolamines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Social Behavior; Thiophenes | 1996 |
Antagonistic effects of S 22153, a new mt1 and MT2 receptor ligand, on the neophobia-reducing properties of melatonin in BALB/c mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Dose-Response Relationship, Drug; Exploratory Behavior; Ligands; Male; Melatonin; Mice; Mice, Inbred BALB C; Motor Activity; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Thiophenes; Time Factors | 1999 |